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Mild elevation of pulmonary vascular resistance predicts mortality regardless of mean pulmonary artery pressure in mild interstitial lung disease
Mild elevation of pulmonary vascular resistance predicts mortality regardless of mean pulmonary artery pressure in mild interstitial lung disease
WHAT IS ALREADY KNOWN ON THIS TOPICPulmonary hypertension (PH) is defined by elevated mean pulmonary arterial pressure (MP...
Development of respiratory care guidelines for Duchenne muscular dystrophy in the UK: key recommendations for clinical practice
Development of respiratory care guidelines for Duchenne muscular dystrophy in the UK: key recommendations for clinical practice
Introduction and scopeThis is a consensus summary from an expert respiratory working group (WG) of UK adult and paediatric...
Does ICS treatment increase the risk of pneumonia in asthma?
Does ICS treatment increase the risk of pneumonia in asthma?
Patients with asthma have an increased risk of being hospitalised for pneumonia. For example, in a study based on the Resp...
Impacts of sex and gender on severe asthma
Impacts of sex and gender on severe asthma
For decades, the unwritten rule for asthma management was ‘Keep it Simple’, with clinicians largely trying to apply a one-...
Unravelling the obesity-asthma connection in childhood and adolescence: does body shape matter?
Unravelling the obesity-asthma connection in childhood and adolescence: does body shape matter?
Given the concurrent worldwide epidemics of childhood obesity and asthma, it is perhaps not surprising that the two have b...
Use of inhaled corticosteroids and the risk of hospitalisation for pneumonia in children with asthma: a nationwide cohort study
Use of inhaled corticosteroids and the risk of hospitalisation for pneumonia in children with asthma: a nationwide cohort study
IntroductionInhaled corticosteroids (ICS) are the cornerstone of asthma pharmacotherapy and a common first-line treatment....
Impact of sex on severe asthma: a cross-sectional retrospective analysis of UK primary and specialist care
Impact of sex on severe asthma: a cross-sectional retrospective analysis of UK primary and specialist care
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Greenhouse gas emissions associated with suboptimal asthma care in the UK: the SABINA healthCARe-Based envirONmental cost of treatment (CARBON) study
Greenhouse gas emissions associated with suboptimal asthma care in the UK: the SABINA healthCARe-Based envirONmental cost of treatment (CARBON) study
IntroductionIn an effort to combat climate change, countries are seeking to decarbonise their economies, and the healthcar...
Mildly elevated pulmonary vascular resistance and worsened survival in PH-ILD: an opportunity for earlier diagnosis and intervention?
Mildly elevated pulmonary vascular resistance and worsened survival in PH-ILD: an opportunity for earlier diagnosis and intervention?
Pulmonary hypertension (PH) is a feared complication of interstitial lung disease (ILD) owing to increased risk for hospit...
Prognostic factors for survival in unresectable stage III EGFR mutation-positive lung adenocarcinoma: impact of pre-CCRT PET-CT
Prognostic factors for survival in unresectable stage III EGFR mutation-positive lung adenocarcinoma: impact of pre-CCRT PET-CT
AbstractPurpose To assess the survival impact of pre-concurrent chemoradiotherapy (CCRT) staging with positron emission to...
Body composition and respiratory outcomes in children: a population-based prospective cohort study
Body composition and respiratory outcomes in children: a population-based prospective cohort study
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Impact of post-COVID-19 condition on health status and activities of daily living: the PRIME post-COVID study
Impact of post-COVID-19 condition on health status and activities of daily living: the PRIME post-COVID study
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Serum cytokine biosignatures for identification of tuberculosis among HIV-positive inpatients
Serum cytokine biosignatures for identification of tuberculosis among HIV-positive inpatients
WHAT IS ALREADY KNOWN ON THIS TOPICDiagnosing tuberculosis (TB) among HIV-positive inpatients remains challenging, mainly ...
Improved pulmonary function and exercise tolerance despite persistent pulmonary fibrosis over 1 year after severe COVID-19 infection
Improved pulmonary function and exercise tolerance despite persistent pulmonary fibrosis over 1 year after severe COVID-19 infection
We conducted a prospective single-centre cohort study of 104 multi-ethnic severe COVID-19 survivors from the first wave of...
Correction: RAGE-induced ILC2 expansion in acute lung injury due to haemorrhagic shock
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Genetic and T2 biomarkers linked to the efficacy of HDM sublingual immunotherapy in asthma
Genetic and T2 biomarkers linked to the efficacy of HDM sublingual immunotherapy in asthma
WHAT IS ALREADY KNOWN ON THIS TOPICHOW THIS STUDY MIGHT AFFECT RESEARCH, PRACTICE OR POLICYIntroductionAsthma is a global ...
Massive thymoma mimicking a pleural mass
Massive thymoma mimicking a pleural mass
A 37-year-old man presented with months of weight loss, dysphagia and fatigue. He was an infrequent smoker, had no medical...
Not all wheeze is asthma
Not all wheeze is asthma
A 41-year-old man previously diagnosed with asthma presented with an influenza-like illness and breathlessness. He was tre...
Protective effect of height on long-term survival of resectable lung cancer: a new feature of the lung cancer paradox
Protective effect of height on long-term survival of resectable lung cancer: a new feature of the lung cancer paradox
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Diagnosis of cystic lung diseases: a position statement from the UK Cystic Lung Disease Rare Disease Collaborative Network
Diagnosis of cystic lung diseases: a position statement from the UK Cystic Lung Disease Rare Disease Collaborative Network
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Decoding pulmonary nodules: can machine learning enhance malignancy risk stratification?
Decoding pulmonary nodules: can machine learning enhance malignancy risk stratification?
Randomised controlled trials, with the National Lung Screening Trial and Dutch-Belgian NELSON trial being the two largest,...
Blood eosinophils take centre stage in predicting the response to sublingual immunotherapy (SLIT): a familiar twist
Blood eosinophils take centre stage in predicting the response to sublingual immunotherapy (SLIT): a familiar twist
Sublingual immunotherapy (SLIT) represents a safer, more comfortable and more convenient allergen immunotherapy than its s...
Survival analysis from the INCREASE study in PH-ILD: evaluating the impact of treatment crossover on overall mortality
Survival analysis from the INCREASE study in PH-ILD: evaluating the impact of treatment crossover on overall mortality
WHAT IS ALREADY KNOWN ON THIS TOPICIn the INCREASE trial, inhaled treprostinil was evaluated in patients with pulmonary hy...
Post-pandemic tuberculosis incidence: potential success of active case finding?
Post-pandemic tuberculosis incidence: potential success of active case finding?
Until 2020, tuberculosis (TB) was annually the number one infectious killer disease globally. When the COVID-19 pandemic s...
Well-differentiated papillary mesothelial tumour: a rare finding on the pleura
Well-differentiated papillary mesothelial tumour: a rare finding on the pleura
A 72-year-old woman presented to the emergency department with a history of non-specific intermittent abdominal pain. The ...
Type-2 inflammation: a key treatable trait associated with lung function decline in chronic airways disease
Type-2 inflammation: a key treatable trait associated with lung function decline in chronic airways disease
The chronic airways diseases, asthma and Chronic Obstructive Pulmonary Disease (COPD), are highly prevalent conditions cau...
Twenty-year-old patient with polyarthritis since childhood showing cysts and ground glass attenuation on HRCT
Twenty-year-old patient with polyarthritis since childhood showing cysts and ground glass attenuation on HRCT
We present a case of a 20-year-old woman reporting polyarthritis, muscle weakness, dyspnoea and multiple intensive care un...
Type-2 inflammation and lung function decline in chronic airway disease in the general population
Type-2 inflammation and lung function decline in chronic airway disease in the general population
WHAT IS ALREADY KNOWN ON THIS TOPICType-2 inflammation is increasingly recognised as an important clinical feature in pati...