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Rosacea in Older Adults and Pharmacologic Treatments
Rosacea in Older Adults and Pharmacologic Treatments
Rosacea is a chronic inflammatory skin condition that is often more severe in older patients. The main clinical features a...
Association of Tumor Necrosis Factor-α Inhibitors with Incident Dementia: Analysis Based on Population-Based Cohort Studies
Association of Tumor Necrosis Factor-α Inhibitors with Incident Dementia: Analysis Based on Population-Based Cohort Studies
Preliminary evidence suggests a possible preventive effect of tumor necrosis factor-α inhibitors (TNFi) on incident d...
Lipid-Lowering Medications are Associated with Reduced Sarcopenia-Related Quality of Life in Older Adults with Hyperlipidemia
Lipid-Lowering Medications are Associated with Reduced Sarcopenia-Related Quality of Life in Older Adults with Hyperlipidemia
Statins medications negatively affect age-associated loss of muscle mass and strength, termed sarcopenia, and neuromuscula...
Patterns of Comorbidities and Prescribing and Dispensing of Non-steroidal Anti-inflammatory Drugs (NSAIDs) Among Patients with Osteoarthritis in the USA: Real-World Study
Patterns of Comorbidities and Prescribing and Dispensing of Non-steroidal Anti-inflammatory Drugs (NSAIDs) Among Patients with Osteoarthritis in the USA: Real-World Study
Osteoarthritis (OA) is a major cause of chronic pain. Non-steroidal anti-inflammatory drugs (NSAIDs) are analgesics common...
Older Canadians’ Perceptions of the Safety, Effectiveness and Accessibility of Cannabis for Medicinal Purposes: A Cross-Sectional Analysis
Older Canadians’ Perceptions of the Safety, Effectiveness and Accessibility of Cannabis for Medicinal Purposes: A Cross-Sectional Analysis
Cannabis use is increasing among older adults, with use primarily for medicinal purposes. Much of the evidence on percepti...
Cumulative Anticholinergic Burden and its Predictors among Older Adults with Alzheimer’s Disease Initiating Cholinesterase Inhibitors
Cumulative Anticholinergic Burden and its Predictors among Older Adults with Alzheimer’s Disease Initiating Cholinesterase Inhibitors
Cumulative anticholinergic burden refers to the cumulative effect of multiple medications with anticholinergic properties....
Management of Scleritis in Older Adults
Management of Scleritis in Older Adults
Scleritis, an inflammatory disease of the eye affecting scleral tissue, presents unique challenges in the older adult popu...
Safety and Efficacy of Cenobamate for the Treatment of Focal Seizures in Older Patients: Post Hoc Analysis of a Phase III, Multicenter, Open-Label Study
Safety and Efficacy of Cenobamate for the Treatment of Focal Seizures in Older Patients: Post Hoc Analysis of a Phase III, Multicenter, Open-Label Study
Cenobamate is an antiseizure medication (ASM) approved in the US and Europe for the treatment of uncontrolled focal seizur...
Real-World Experience of Immune-Checkpoint Inhibitors in Older Patients with Advanced Cutaneous Squamous Cell Carcinoma
Real-World Experience of Immune-Checkpoint Inhibitors in Older Patients with Advanced Cutaneous Squamous Cell Carcinoma
Older patients are often underrepresented in clinical trials owing to exclusionary comorbidities, which are more common wi...
Post-Stroke Depression in Older Adults: An Overview
Post-Stroke Depression in Older Adults: An Overview
Detailed data on post-stroke depression (PSD) in older adults are limited in spite of the high vulnerability of this popul...
The Difficulties of Managing Pain in People Living with Frailty: The Potential for Digital Phenotyping
The Difficulties of Managing Pain in People Living with Frailty: The Potential for Digital Phenotyping
Pain and frailty are closely linked. Chronic pain is a risk factor for frailty, and frailty is a risk factor for pain. Peo...
Impact of Immunosenescence in Older Kidney Transplant Recipients: Associated Clinical Outcomes and Possible Risk Stratification for Immunosuppression Reduction
Impact of Immunosenescence in Older Kidney Transplant Recipients: Associated Clinical Outcomes and Possible Risk Stratification for Immunosuppression Reduction
The number of older individuals receiving a kidney transplant as replacement therapy has significantly increased in the pa...
Proton Pump Inhibitor Use and the Risk of Cardiovascular Complications and Death in Older Adults with Diabetes: A Population-Based Cohort Study
Proton Pump Inhibitor Use and the Risk of Cardiovascular Complications and Death in Older Adults with Diabetes: A Population-Based Cohort Study
The unfavorable effect of proton pump inhibitors (PPIs) on cardiovascular (CV) outcomes and mortality was reported in the ...
Helicobacter pylori Eradication Treatment in Older Patients
Helicobacter pylori Eradication Treatment in Older Patients
Helicobacter pylori is the main etiopathogenetic factor of chronic gastritis, peptic ulcer disease and gastric cancer. The...
Development and Pilot Testing of an Algorithm-Based Approach to Anticholinergic Deprescribing in Older Patients
Development and Pilot Testing of an Algorithm-Based Approach to Anticholinergic Deprescribing in Older Patients
Adverse anticholinergic drug reactions are common, yet evidence on how to reduce exposure to anticholinergic activity and ...
The Current Landscape of Pharmacotherapies for Sarcopenia
The Current Landscape of Pharmacotherapies for Sarcopenia
Sarcopenia is a skeletal muscle disorder characterized by progressive and generalized decline in muscle mass and function....
Are Lists of Potentially Inappropriate Medications Associated with Hospital Readmissions? A Systematic Review
Are Lists of Potentially Inappropriate Medications Associated with Hospital Readmissions? A Systematic Review
Suboptimal prescribing, including the prescription of potentially inappropriate medications (PIM), is frequent in patients...
Evaluating Provider and Pharmacy Discordance in Potential Calcium Channel Blocker–Loop Diuretic Prescribing Cascade
Evaluating Provider and Pharmacy Discordance in Potential Calcium Channel Blocker–Loop Diuretic Prescribing Cascade
Prescribing cascades occur when a drug-induced adverse event is treated with a new medication. Identifying clinical scenar...
Diagnosis and Pharmacological Management of Microscopic Colitis in Geriatric Care
Diagnosis and Pharmacological Management of Microscopic Colitis in Geriatric Care
Microscopic colitis, a diagnosis under the umbrella term of inflammatory bowel disease, is a prevalent cause of watery dia...
Comment on: “Patient Perceptions of Opioids and Benzodiazepines and Attitudes Toward Deprescribing”
Comment on: “Patient Perceptions of Opioids and Benzodiazepines and Attitudes Toward Deprescribing”
Funding Dr E Reeve is funded by a National Health and Medical Resea...
Authors’ Reply to Langford et al.: “Patient Perceptions of Opioids and Benzodiazepines and Attitudes Toward Deprescribing”
Authors’ Reply to Langford et al.: “Patient Perceptions of Opioids and Benzodiazepines and Attitudes Toward Deprescribing”
Funding This work was funded by the Centers for Disease Control and...
Correction to: Prevalence and factors associated with inappropriate dosing of apixaban and rivaroxaban in hospitalized older adults with atrial fibrillation: a cross‑sectional study
Correction to: Prevalence and factors associated with inappropriate dosing of apixaban and rivaroxaban in hospitalized older adults with atrial fibrillation: a cross‑sectional study
Authors and AffiliationsAcute Geriatrics Unit, Charles Foix Hospital, APHP Sorbonne University, Ivry-sur-Seine, FranceThéo...
Do Proton Pump Inhibitors Reduce Upper Gastrointestinal Bleeding in Older Patients with Atrial Fibrillation Treated with Oral Anticoagulants? A Nationwide Cohort Study in France
Do Proton Pump Inhibitors Reduce Upper Gastrointestinal Bleeding in Older Patients with Atrial Fibrillation Treated with Oral Anticoagulants? A Nationwide Cohort Study in France
Proton pump inhibitors (PPIs) are largely used in older adults and data are needed in off-label indications, such as the p...
Individualized Dosing Patterns in the Treatment of Older Patients with Gastrointestinal Stromal Tumors: Results of a Registry-Based Observational National Cohort Study Including 871 Patients
Individualized Dosing Patterns in the Treatment of Older Patients with Gastrointestinal Stromal Tumors: Results of a Registry-Based Observational National Cohort Study Including 871 Patients
While the effectiveness of tyrosine kinase inhibitors (TKIs) seems similar in older patients with gastrointestinal stromal...
Potentially Inappropriate Psychotropic Drugs in Nursing Homes: An Italian Observational Study
Potentially Inappropriate Psychotropic Drugs in Nursing Homes: An Italian Observational Study
Physicians often face difficulties in selecting appropriate medications for older adults with multiple comorbidities. As p...
Cutaneous Lupus Erythematosus: Review and Considerations for Older Populations
Cutaneous Lupus Erythematosus: Review and Considerations for Older Populations
Though more common earlier in life, increasing attention is being focused on the development of cutaneous lupus erythemato...
A Trial-Based Cost-Utility Analysis of a Medication Optimization Intervention Versus Standard Care in Older Adults
A Trial-Based Cost-Utility Analysis of a Medication Optimization Intervention Versus Standard Care in Older Adults
Older adults are at greater risk of medication-related harm than younger adults. The Integrated Medication Management mode...
Evaluating the Safety of an Educational Deprescribing Intervention: Lessons from the Optimize Trial
Evaluating the Safety of an Educational Deprescribing Intervention: Lessons from the Optimize Trial
Patients, family members, and clinicians express concerns about potential adverse drug withdrawal events (ADWEs) following...
Potentially inappropriate prescribing in multimorbid and polymedicated older adults with AF: A Systematic Review and Meta-Analysis
Potentially inappropriate prescribing in multimorbid and polymedicated older adults with AF: A Systematic Review and Meta-Analysis
Polypharmacy in multimorbid older patients with atrial fibrillation (AF) is a risk factor for potentially inappropriate pr...
Current Pharmacological Therapies for the Management of Spondyloarthritis: Special Considerations in Older Patients
Current Pharmacological Therapies for the Management of Spondyloarthritis: Special Considerations in Older Patients
Spondylarthritis (SpA) is generally observed in young male patients but can be diagnosed in older patients. These cases co...
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