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Cribriform Morular Thyroid Carcinoma – Ultimobranchial Pouch-Related? Deep Molecular Insights of a Unique Case
Cribriform Morular Thyroid Carcinoma – Ultimobranchial Pouch-Related? Deep Molecular Insights of a Unique Case
A 44-year-old female patient with a familial adenomatous polyposis (FAP) was diagnosed with a cribriform morular thyroid c...
Gastric Amphicrine Carcinoma Showing Neuroendocrine and Pancreatic Acinar Cell Differentiation. Lesson from a Challenging Case Opening New Perspectives in the Diagnostic Work-Up of Gastric Neuroendocrine Neoplasms
Gastric Amphicrine Carcinoma Showing Neuroendocrine and Pancreatic Acinar Cell Differentiation. Lesson from a Challenging Case Opening New Perspectives in the Diagnostic Work-Up of Gastric Neuroendocrine Neoplasms
Amphicrine carcinomas are epithelial neoplasms composed of cells with co-existing exocrine-neuroendocrine phenotype and ar...
Progress in Adrenal Cortical Neoplasms: From Predictive Histomorphology to FLCN-Driven Germline Pathogenesis and the Prognostic Performance of Multiparameter Scoring Systems in Pediatric Adrenal Cortical Neoplasms
Progress in Adrenal Cortical Neoplasms: From Predictive Histomorphology to FLCN-Driven Germline Pathogenesis and the Prognostic Performance of Multiparameter Scoring Systems in Pediatric Adrenal Cortical Neoplasms
Juhlin CC, Bertherat J, Giordano TJ, Hammer GD, Sasano H, Mete O. What Did We Learn from the Molecular Biology of Adrenal ...
3rd Edition of Diagnostic Pathology: Endocrine by Vania Nosé
3rd Edition of Diagnostic Pathology: Endocrine by Vania Nosé
Share this articleAnyone you share the following link with will be able to read this content:Get shareable linkSorry, a sh...
Inflammatory and Infectious Disorders in Endocrine Pathology
Inflammatory and Infectious Disorders in Endocrine Pathology
A variety of inflammatory conditions may directly involve the endocrine glands, leading to endocrine dysfunction that can ...
Clinical and Pathological Features and Gene Expression Profiles of Clinically Aggressive Papillary Thyroid Carcinomas
Clinical and Pathological Features and Gene Expression Profiles of Clinically Aggressive Papillary Thyroid Carcinomas
Papillary thyroid carcinoma (PTC) is considered an indolent neoplasm but it may demonstrate aggressive behavior. We aimed ...
High Grade Differentiated Follicular Cell-Derived Thyroid Carcinoma Versus Poorly Differentiated Thyroid Carcinoma: A Clinicopathologic Analysis of 41 Cases
High Grade Differentiated Follicular Cell-Derived Thyroid Carcinoma Versus Poorly Differentiated Thyroid Carcinoma: A Clinicopathologic Analysis of 41 Cases
Criteria overlap for separating between malignant follicular epithelial cell-derived thyroid gland neoplasms with high gra...
Thyroid Nodules and Follicular Cell-Derived Thyroid Carcinomas in Children
Thyroid Nodules and Follicular Cell-Derived Thyroid Carcinomas in Children
Although pediatric thyroid tumors have many similarities to those occurring in adults, significant differences are also re...
The Driver Role of Pathologists in Endocrine Oncology: What Clinicians Seek in Pathology Reports
The Driver Role of Pathologists in Endocrine Oncology: What Clinicians Seek in Pathology Reports
Endocrine neoplasia represents an increasingly broad spectrum of disorders. Endocrine neoplasms range from incidental find...
Pediatric Adrenocortical Neoplasms: A Study Comparing Three Histopathological Scoring Systems
Pediatric Adrenocortical Neoplasms: A Study Comparing Three Histopathological Scoring Systems
Adrenocortical neoplasms are rare in childhood. Their histopathological categorization into benign and malignant is often ...
Mucinous Amphicrine Carcinoma of the Pancreas: A Diagnostic Pitfall
Mucinous Amphicrine Carcinoma of the Pancreas: A Diagnostic Pitfall
We appreciate the laboratory technicians at Tohoku University Hospital for helping with the in preparation of the histolog...
Typical “BRAFV600E-Like” Atypia in Papillary Thyroid Carcinoma: A Morphologic Sign of a Driver Mutation
Typical “BRAFV600E-Like” Atypia in Papillary Thyroid Carcinoma: A Morphologic Sign of a Driver Mutation
Turchini J, Sioson L, Clarkson A, Sheen A, Delbridge L, Glover A, Sywak M, Sidhu S, Gill AJ. Endocr Pathol. 2023; 34(1):11...
Preoperative Risk Stratification of Follicular-patterned Thyroid Lesions on Core Needle Biopsy by Histologic Subtyping and RAS Variant-specific Immunohistochemistry
Preoperative Risk Stratification of Follicular-patterned Thyroid Lesions on Core Needle Biopsy by Histologic Subtyping and RAS Variant-specific Immunohistochemistry
Follicular-patterned lesions often have indeterminate results (diagnostic category III or IV) by core needle biopsy (CNB) ...
Morphological Harbingers of ARMC5-Pathogenic Variant-Related Bilateral Macronodular Adrenocortical Disease
Morphological Harbingers of ARMC5-Pathogenic Variant-Related Bilateral Macronodular Adrenocortical Disease
Bilateral macronodular adrenocortical disease (BMAD) is a neoplastic disease associated with a high frequency of germline ...
The Unique Importance of Differentiation and Function in Endocrine Neoplasia
The Unique Importance of Differentiation and Function in Endocrine Neoplasia
The assessment of cell differentiation in endocrine neoplasms involves not only the identification of a cell’s struc...
Insights Obtained from the Nontumorous Glandular Tissue in Patients with Endocrine Tumors
Insights Obtained from the Nontumorous Glandular Tissue in Patients with Endocrine Tumors
The pathology of neoplasia tends to focus on the tumor that requires characterization, grading, and staging. However, nont...
Prognostic Value of Microscopic Tumor Necrosis in Adrenal Cortical Carcinoma
Prognostic Value of Microscopic Tumor Necrosis in Adrenal Cortical Carcinoma
Adrenal cortical carcinoma (ACC) is an uncommon neoplasm with variable prognosis. Several histologic criteria have been id...
The Spectrum of Endocrine Pathology
The Spectrum of Endocrine Pathology
Endocrine pathology comprises a spectrum of disorders originating in various sites throughout the body. Some disorders aff...
Update on C-Cell Neuroendocrine Neoplasm: Prognostic and Predictive Histopathologic and Molecular Features of Medullary Thyroid Carcinoma
Update on C-Cell Neuroendocrine Neoplasm: Prognostic and Predictive Histopathologic and Molecular Features of Medullary Thyroid Carcinoma
Medullary thyroid carcinoma (MTC) is a C-cell-derived epithelial neuroendocrine neoplasm. With the exception of rare examp...
Impact of Morphology in the Genotype and Phenotype Correlation of Bilateral Macronodular Adrenocortical Disease (BMAD): A Series of Clinicopathologically Well-Characterized 35 Cases
Impact of Morphology in the Genotype and Phenotype Correlation of Bilateral Macronodular Adrenocortical Disease (BMAD): A Series of Clinicopathologically Well-Characterized 35 Cases
Bilateral macronodular adrenocortical disease (BMAD) is characterized by the development of adrenal macronodules resulting...
Sarcomatous Transformation of a Medically Treated Lactotroph Pituitary Neuroendocrine Tumor?
Sarcomatous Transformation of a Medically Treated Lactotroph Pituitary Neuroendocrine Tumor?
A biphasic neoplasm was found, with a well-defined but focally intermingled PitNET and a high-grade sarcoma, not otherwise...
The Impact of the 2022 WHO Classification of Thyroid Neoplasms on Everyday Practice of Cytopathology
The Impact of the 2022 WHO Classification of Thyroid Neoplasms on Everyday Practice of Cytopathology
This review outlines how the alterations in the 5th edition of the WHO Classification of Endocrine and Neuroendocrine Tumo...
Diagnostic, Prognostic, and Predictive Role of Ki67 Proliferative Index in Neuroendocrine and Endocrine Neoplasms: Past, Present, and Future
Diagnostic, Prognostic, and Predictive Role of Ki67 Proliferative Index in Neuroendocrine and Endocrine Neoplasms: Past, Present, and Future
The introduction of Ki67 immunohistochemistry in the work-up of neuroendocrine neoplasms (NENs) has opened a new approach ...
Thyroblastoma—a Primitive Multilineage Thyroid Neoplasm with Somatic DICER1 Alteration
Thyroblastoma—a Primitive Multilineage Thyroid Neoplasm with Somatic DICER1 Alteration
Agaimy A, Nose V, Sobrinho-Simoes M. WHO Classification of Tumours Editorial Board. Thyroblastoma. WHO Classification of E...
Sclerosing Mucoepidermoid Carcinoma with Eosinophilia of the Thyroid and Mucoepidermoid Carcinoma of the Thyroid: What’s in a Name?
Sclerosing Mucoepidermoid Carcinoma with Eosinophilia of the Thyroid and Mucoepidermoid Carcinoma of the Thyroid: What’s in a Name?
Le HT, Nguyen TPX, Hirokawa M, et al., Primary thyroid mucoepidermoid carcinoma (MEC) is clinically, prognostically and mo...
The Thyroid Pathologist Meets Therapeutic Pharmacology
The Thyroid Pathologist Meets Therapeutic Pharmacology
The effects of many pharmacological agents on thyroid function are well known. Direct influences on measurements of thyroi...
The Presence of Typical “BRAFV600E-Like” Atypia in Papillary Thyroid Carcinoma is Highly Specific for the Presence of the BRAFV600E Mutation
The Presence of Typical “BRAFV600E-Like” Atypia in Papillary Thyroid Carcinoma is Highly Specific for the Presence of the BRAFV600E Mutation
Papillary thyroid carcinomas (PTCs) are driven by a variety of molecular abnormalities including BRAF, RAS, ALK, RET, and ...
High-Grade Non-Anaplastic Thyroid Carcinomas of Follicular Cell Origin: A Review of Poorly Differentiated and High-Grade Differentiated Carcinomas
High-Grade Non-Anaplastic Thyroid Carcinomas of Follicular Cell Origin: A Review of Poorly Differentiated and High-Grade Differentiated Carcinomas
Poorly differentiated thyroid carcinoma (PDTC) and high-grade differentiated thyroid carcinoma (HGDTC) are considered high...
FLCN-Driven Functional Adrenal Cortical Carcinoma with High Mitotic Tumor Grade: Extending the Endocrine Manifestations of Birt-Hogg-Dubé Syndrome
FLCN-Driven Functional Adrenal Cortical Carcinoma with High Mitotic Tumor Grade: Extending the Endocrine Manifestations of Birt-Hogg-Dubé Syndrome
Adrenal cortical carcinoma is an aggressive and rare malignancy of steroidogenic cells of the adrenal gland. Most adult ad...
TOP2A Expression in Pheochromocytoma and Abdominal Paraganglioma: a Marker of Poor Clinical Outcome?
TOP2A Expression in Pheochromocytoma and Abdominal Paraganglioma: a Marker of Poor Clinical Outcome?
Pheochromocytoma and abdominal paraganglioma (PPGL) are rare neuroendocrine tumors originating from chromaffin cells. Even...
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