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Recent Insights into the Environmental Determinants of Childhood Asthma
Recent Insights into the Environmental Determinants of Childhood Asthma
Ubiquitous environmental exposures, including ambient air pollutants, are linked to the development and severity of childh...
Alpha-Tryptase as a Risk-Modifying Factor for Mast Cell–Mediated Reactions
Alpha-Tryptase as a Risk-Modifying Factor for Mast Cell–Mediated Reactions
To provide an overview on the current understanding of genetic variability in human tryptases and summarize the literature...
The Natural History and Risk Factors for the Development of Food Allergies in Children and Adults
The Natural History and Risk Factors for the Development of Food Allergies in Children and Adults
This narrative review explores food allergy prevalence and natural history stratified by life stages, especially in contex...
Predictors of Clonality and Underlying Mastocytosis in Mast Cell Activation Syndromes
Predictors of Clonality and Underlying Mastocytosis in Mast Cell Activation Syndromes
Mast cell (MC) activation can present with a wide range of symptoms. The mechanisms that cause such activation are varied....
Precautionary Allergen Labeling: Avoidance for All?
Precautionary Allergen Labeling: Avoidance for All?
Precautionary allergen labeling (PAL) suggests the risk of unintended allergen presence (UAP) in food but is unregulated i...
Psychosocial Impact of Food Allergy on Children and Adults and Practical Interventions
Psychosocial Impact of Food Allergy on Children and Adults and Practical Interventions
IgE- and non-IgE-mediated food allergies are increasing in prevalence in children and adults worldwide. A food allergy dia...
Using the Right Criteria for MCAS
Using the Right Criteria for MCAS
The current article aims to provide a comprehensive update on diagnostic criteria for mast cell activation syndrome (MCAS)...
Urine Mast Cell Mediators in the Evaluation and Diagnosis of Mast Cell Activation Syndrome
Urine Mast Cell Mediators in the Evaluation and Diagnosis of Mast Cell Activation Syndrome
Mast cell activation syndrome is defined by severe, episodic, and recurrent symptoms induced by mast cell mediators with o...
Mast Cell–Targeting Therapies in Mast Cell Activation Syndromes
Mast Cell–Targeting Therapies in Mast Cell Activation Syndromes
Provide an overview of the expanding landscape of mast cell (MC)–targeting treatments in mast cell activation syndro...
Mast Cells in Aspirin-Exacerbated Respiratory Disease
Mast Cells in Aspirin-Exacerbated Respiratory Disease
Aspirin-exacerbated respiratory disease (AERD) is a syndrome of high type 2 inflammation and is known to critically involv...
Epidemiology and the Growing Epidemic of Food Allergy in Children and Adults Across the Globe
Epidemiology and the Growing Epidemic of Food Allergy in Children and Adults Across the Globe
Food allergies are immune-mediated, complex disorders, which are the source of increasing health concern worldwide. The go...
A Review of Pollen Counting Networks: From the Nineteenth Century into the Twenty-first Century
A Review of Pollen Counting Networks: From the Nineteenth Century into the Twenty-first Century
Pollen is enormously important to the human experience. As pollen became germane to human health in the late nineteenth ce...
Biomarkers of Autoimmune Chronic Spontaneous Urticaria
Biomarkers of Autoimmune Chronic Spontaneous Urticaria
Chronic spontaneous urticaria and chronic inducible urticaria (CSU/CindU) are caused by mast cell and basophil activation ...
The Impact of Ambient and Wildfire Air Pollution on Rhinosinusitis and Olfactory Dysfunction
The Impact of Ambient and Wildfire Air Pollution on Rhinosinusitis and Olfactory Dysfunction
With increasing industrialization, exposure to ambient and wildfire air pollution is projected to increase, necessitating ...
Effects of Endoscopic Sinus Surgery on Olfactory Function
Effects of Endoscopic Sinus Surgery on Olfactory Function
To review the effects of endoscopic sinus surgery and endonasal approaches to the skull base on olfaction. Advancements in...
Type 2 Biomarkers for the Indication and Response to Biologics in CRSwNP
Type 2 Biomarkers for the Indication and Response to Biologics in CRSwNP
Three biologics targeting type 2 inflammation have been approved for the treatment of severe and uncontrolled chronic rhin...
Expert Consensus on SABA Use for Asthma Clinical Decision-Making: A Delphi Approach
Expert Consensus on SABA Use for Asthma Clinical Decision-Making: A Delphi Approach
A modified Delphi process was undertaken to provide a US expert-led consensus to guide clinical action on short-acting bet...
Treatments of Epistaxis in Hereditary Hemorrhagic Telangiectasia: Systematic Review and Network Meta-Analysis
Treatments of Epistaxis in Hereditary Hemorrhagic Telangiectasia: Systematic Review and Network Meta-Analysis
To analyze and compare the effects of epistaxis treatments for Hereditary Hemorrhagic Telangiectasia (HHT) patients. Of to...
Neuromyelitis Optica: Pathogenesis Overlap with Other Autoimmune Diseases
Neuromyelitis Optica: Pathogenesis Overlap with Other Autoimmune Diseases
Neuromyelitis optica (NMO) is an auto-immune disease essentially depicted by optic neuritis and transverse myelitis. Per s...
An Emerging Role of Extracellular Traps in Chronic Rhinosinusitis
An Emerging Role of Extracellular Traps in Chronic Rhinosinusitis
Chronic rhinosinusitis (CRS) is a complicated, heterogeneous disease likely caused by inflammatory and infectious factors....
Overview and Current Advances in Dapsone Hypersensitivity Syndrome
Overview and Current Advances in Dapsone Hypersensitivity Syndrome
As a sulfone antibacterial agent, dapsone has been widely used to treat leprosy. Moreover, dapsone is also used in many im...
Allergen Stability in Food Allergy: A Clinician’s Perspective
Allergen Stability in Food Allergy: A Clinician’s Perspective
The globally rising food allergy prevalence is associated with the urgent need for new disease prevention methods, efficie...
Effects of Allergen Exposure and Environmental Risk Factors in Schools on Childhood Asthma
Effects of Allergen Exposure and Environmental Risk Factors in Schools on Childhood Asthma
This review aims to assess the prevalence of common allergen exposures and environmental risk factors for asthma in school...
The Role of IgA in the Manifestation and Prevention of Allergic Immune Responses
The Role of IgA in the Manifestation and Prevention of Allergic Immune Responses
Immunoglobulin A (IgA) mediates immune exclusion of antigens in the gut. Notably, IgA plays also a role in the prevention ...