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Opposing roles by KRAS and BRAF mutation on immune cell infiltration in colorectal cancer – possible implications for immunotherapy
Opposing roles by KRAS and BRAF mutation on immune cell infiltration in colorectal cancer – possible implications for immunotherapy
The immune response has important clinical value in colorectal cancer (CRC) in both prognosis and response to immunotherap...
Risk-reducing mastectomy and breast cancer mortality in women with a BRCA1 or BRCA2 pathogenic variant: an international analysis
Risk-reducing mastectomy and breast cancer mortality in women with a BRCA1 or BRCA2 pathogenic variant: an international analysis
Risk-reducing mastectomy (RRM) is offered to women with a BRCA1 or BRCA2 pathogenic variant, however, there are limited da...
Aspirin and cancer treatment: systematic reviews and meta-analyses of evidence: for and against
Aspirin as a possible treatment of cancer has been of increasing interest for over 50 years, but the balance of the risks ...
Health benefits and harms of mammography screening in older women (75+ years)—a systematic review
Health benefits and harms of mammography screening in older women (75+ years)—a systematic review
There is little evidence on the balance between potential benefits and harms of mammography screening in women 75 years an...
Low-dose metronomic cisplatin as an antiangiogenic and anti-inflammatory strategy for cancer
Low-dose metronomic cisplatin as an antiangiogenic and anti-inflammatory strategy for cancer
Conventional chemotherapy is based on the maximum tolerated dose (MTD) and requires treatment-free intervals to restore no...
Multivitamin use and all-cause and cause-specific mortality in cancer survivors
Multivitamin use and all-cause and cause-specific mortality in cancer survivors
Despite no sufficient evidence on benefits and harms of multivitamin use, cancer survivors use multivitamins as a self-car...
Educational attainment in survivors of childhood cancer in Denmark, Finland, and Sweden
Educational attainment in survivors of childhood cancer in Denmark, Finland, and Sweden
Survivors of childhood cancer may face difficulties at school. We investigated whether childhood cancer affects attainment...
Unlocking hidden potential: advancements, approaches, and obstacles in repurposing drugs for cancer therapy
Unlocking hidden potential: advancements, approaches, and obstacles in repurposing drugs for cancer therapy
High rates of failure, exorbitant costs, and the sluggish pace of new drug discovery and development have led to a growing...
Accuracy of HPV E6/E7 oncoprotein tests to detect high-grade cervical lesions: a systematic literature review and meta-analysis
Accuracy of HPV E6/E7 oncoprotein tests to detect high-grade cervical lesions: a systematic literature review and meta-analysis
Cervical carcinogenesis is mediated by the HPV-E6 and E7 oncoproteins, considered as biomarkers usable in managing screen-...
Resistance to osimertinib in advanced EGFR-mutated NSCLC: a prospective study of molecular genotyping on tissue and liquid biopsies
Resistance to osimertinib in advanced EGFR-mutated NSCLC: a prospective study of molecular genotyping on tissue and liquid biopsies
Resistance to osimertinib in advanced EGFR-mutated non-small cell lung cancer (NSCLC) constitutes a significant challenge ...
Progress of immune checkpoint inhibitors therapy for non-small cell lung cancer with liver metastases
Nearly one-fifth of patients with non-small cell Lung Cancer (NSCLC) will develop liver metastases (LMs), and the overall ...
Enlarged tumour-draining lymph node with immune-activated profile predict favourable survival in non-metastatic colorectal cancer
Enlarged tumour-draining lymph node with immune-activated profile predict favourable survival in non-metastatic colorectal cancer
The tumour-draining lymph node (TDLN) plays a pivotal role in the suppression of malignant tumour, however, the immunologi...
Fascin-1 expression is associated with neuroendocrine prostate cancer and directly suppressed by androgen receptor
Fascin-1 expression is associated with neuroendocrine prostate cancer and directly suppressed by androgen receptor
Neuroendocrine prostate cancer (NEPC) is an aggressive form of prostate cancer, arising from resistance to androgen-depriv...
Supporting gut health with medicinal cannabis in people with advanced cancer: potential benefits and challenges
Supporting gut health with medicinal cannabis in people with advanced cancer: potential benefits and challenges
The side effects of cancer therapy continue to cause significant health and cost burden to the patient, their friends and ...
Body composition and cancer survival: a narrative review
Body composition and cancer survival: a narrative review
Interest in understanding the relationship between body composition and cancer survival has remained strong for decades, w...