SCI时时刷

search
+
ALLTogether recommendations for biobanking samples from patients with acute lymphoblastic leukaemia: a modified Delphi study
ALLTogether recommendations for biobanking samples from patients with acute lymphoblastic leukaemia: a modified Delphi study
Acute lymphoblastic leukaemia (ALL) is a rare and heterogeneous disease. The ALLTogether consortium has implemented a trea...
Enhanced CXCL10 expression in mast cells for cutaneous neurofibroma presenting with pain and itch
Enhanced CXCL10 expression in mast cells for cutaneous neurofibroma presenting with pain and itch
Cutaneous neurofibroma (cNF) presenting with pain and itch substantially affects the quality of life. The CXCL10/CXCR3 axi...
GDP-bound Rab37 modulates M2-like tumor-associated macrophage polarization by attenuating STAT1 translocation to downregulate the type I IFN pathway
GDP-bound Rab37 modulates M2-like tumor-associated macrophage polarization by attenuating STAT1 translocation to downregulate the type I IFN pathway
Tumor-associated macrophages (TAMs) in the tumor microenvironment (TME) primarily polarize into the M2-phenotype. Our prev...
Hot beverage intake and oesophageal cancer in the UK Biobank: prospective cohort study
Drinking maté, a type of tea consumed at a very hot temperature in South America has been considered as a risk factor...
The long noncoding RNA lncZBTB10 facilitates AR function via S-palmitoylation to promote prostate cancer progression and abiraterone resistance
The long noncoding RNA lncZBTB10 facilitates AR function via S-palmitoylation to promote prostate cancer progression and abiraterone resistance
Activation of androgen receptor (AR) by androgen binding to its ligand-binding domain (LBD) has led to the development of ...
Correction: Impact of lymph node metastasis on immune microenvironment and prognosis in colorectal cancer liver metastasis: insights from multiomics profiling
Correction: Impact of lymph node metastasis on immune microenvironment and prognosis in colorectal cancer liver metastasis: insights from multiomics profiling
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which...
Apolipoprotein D is crucial for promoting perineural invasion in salivary adenoid cystic carcinoma
Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To ...
Associations of mucinous differentiation and mucin expression with immune cell infiltration and prognosis in colorectal adenocarcinoma
Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To ...
Treating tobacco dependency in cancer care: essential, cost-effective, and feasible, yet overlooked
Treating tobacco dependency in patients diagnosed with cancer delivers substantial benefits; improved overall survival, re...
Lymph node yield as a surrogate marker for tumour biology and prognosis in colon cancer
Lymph node yield as a surrogate marker for tumour biology and prognosis in colon cancer
We interrogated two large national databases to explore the underlying mechanisms and institutional effects of the known a...
Retraction Note: Expression of E-cadherin repressors SNAIL, ZEB1 and ZEB2 by tumour and stromal cells influences tumour-budding phenotype and suggests heterogeneity of stromal cells in pancreatic cancer
Authors and AffiliationsTranslational Research Unit, Institute of Pathology, University of Bern, Murtenstrasse 31, Bern, C...
Feasibility and efficacy of therapeutic drug monitoring of abiraterone in metastatic castration resistant prostate cancer patients
Feasibility and efficacy of therapeutic drug monitoring of abiraterone in metastatic castration resistant prostate cancer patients
Previous studies demonstrated better outcomes for mCRPC (metastatic castration resistant prostate cancer) patients with hi...
Significance of homologous recombinant deficiency as a biomarker for drug sensitivity in colorectal cancer
Significance of homologous recombinant deficiency as a biomarker for drug sensitivity in colorectal cancer
Colorectal cancer (CRC) is a substantial global health concern due to its limited treatment options, especially for oxalip...
Intratumoral and peritumoral PET/CT-based radiomics for non-invasively and dynamically predicting immunotherapy response in NSCLC
Intratumoral and peritumoral PET/CT-based radiomics for non-invasively and dynamically predicting immunotherapy response in NSCLC
We aimed to develop a machine learning model based on intratumoral and peritumoral 18F-FDG PET/CT radiomics to non-invasiv...
Pseudo acute kidney injury in patients receiving CDK4/6 inhibitors
Pseudo acute kidney injury in patients receiving CDK4/6 inhibitors
CDK4/6 inhibitors (CDK4/6i) improve progression-free survival in patients with advanced oestrogen-receptor-positive breast...
Identification of increased dedifferentiation along the Prom1+ cancer cells in Müllerian adenosarcoma with sarcomatous overgrowth
Identification of increased dedifferentiation along the Prom1+ cancer cells in Müllerian adenosarcoma with sarcomatous overgrowth
Müllerian adenosarcoma (MA) is a rare tumour accounts for 5–7% of uterine sarcomas. Tumours with sarcomatous ov...
Correction: Machine learning-based decision support model for selecting intra-arterial therapies for unresectable hepatocellular carcinoma: A national real-world evidence-based study
These authors contributed equally: Chao An, Ran Wei.Beijing Luhe Hospital Affiliated to Capital Medical University, Beijin...
RNA methylation of CD47 mediates tumor immunosuppression in EGFR-TKI resistant NSCLC
RNA methylation of CD47 mediates tumor immunosuppression in EGFR-TKI resistant NSCLC
Although immune checkpoint inhibitors (ICIs) have been successfully utilized in patients with non-small cell lung cancer (...
Elevated serum levels of GPX4, NDUFS4, PRDX5, and TXNRD2 as predictive biomarkers for castration resistance in prostate cancer patients: an exploratory study
Elevated serum levels of GPX4, NDUFS4, PRDX5, and TXNRD2 as predictive biomarkers for castration resistance in prostate cancer patients: an exploratory study
Prostate cancer (PCa) is a heterogeneous disease affecting over 14% of the male population worldwide. Although patients of...
Loss of ARID1A accelerates prostate tumourigenesis with a proliferative collagen-poor phenotype through co-operation with AP1 subunit cFos
Loss of ARID1A accelerates prostate tumourigenesis with a proliferative collagen-poor phenotype through co-operation with AP1 subunit cFos
Prostate cancer (PC) is the commonest male visceral cancer, and second leading cause of cancer mortality in men in the Wes...
Semi-mechanistic efficacy model for PARP + ATR inhibitors—application to rucaparib and talazoparib in combination with gartisertib in breast cancer PDXs
Semi-mechanistic efficacy model for PARP + ATR inhibitors—application to rucaparib and talazoparib in combination with gartisertib in breast cancer PDXs
Promising cancer treatments, such as DDR inhibitors, are often challenged by the heterogeneity of responses in clinical tr...
Extracellular vesicles from pancreatic cancer and its tumour microenvironment promote increased Schwann cell migration
Extracellular vesicles from pancreatic cancer and its tumour microenvironment promote increased Schwann cell migration
Pancreatic ductal adenocarcinoma (PDAC) exhibits a high frequency of neural invasion (NI). Schwann cells (SCs) have been s...
Regulatory non-coding somatic mutations as drivers of neuroblastoma
Regulatory non-coding somatic mutations as drivers of neuroblastoma
Emerging evidence suggests that non-coding somatic single nucleotide variants (SNVs) in cis-regulatory elements (CREs) con...
Sodium nitrite orchestrates macrophage mimicry of tongue squamous carcinoma cells to drive lymphatic metastasis
Sodium nitrite orchestrates macrophage mimicry of tongue squamous carcinoma cells to drive lymphatic metastasis
Tongue squamous cell carcinoma (TSCC) is a malignant oral cancer with unclear pathogenesis that shows a tendency for early...
A UK population-based case-control study of blood tests before cancer diagnosis in patients with non-specific abdominal symptoms
A UK population-based case-control study of blood tests before cancer diagnosis in patients with non-specific abdominal symptoms
Abnormal results in commonly used primary care blood tests could be early markers of cancer in patients presenting with no...
Alkaline phosphatase decline and pain response as predictors of overall survival benefit in patients treated with radium-223: a post hoc analysis of the REASSURE study
Alkaline phosphatase decline and pain response as predictors of overall survival benefit in patients treated with radium-223: a post hoc analysis of the REASSURE study
Alkaline phosphatase (ALP) declines and pain responses can occur during radium-223 (223Ra) treatment, but their associatio...
Correction: Cardiotoxicity following thoracic radiotherapy for lung cancer
Schytte T, Hansen O, Stolberg-Rohr T, Brink C. Cardiac toxicity and radiation dose to the heart in definitive treated non-...
Oxaliplatin induces pyroptosis in hepatoma cells and enhances antitumor immunity against hepatocellular carcinoma
Oxaliplatin induces pyroptosis in hepatoma cells and enhances antitumor immunity against hepatocellular carcinoma
Pyroptosis is closely associated with chemotherapeutic drugs and immune response. Here, we investigated whether oxaliplati...
Impact of lymph node metastasis on immune microenvironment and prognosis in colorectal cancer liver metastasis: insights from multiomics profiling
Impact of lymph node metastasis on immune microenvironment and prognosis in colorectal cancer liver metastasis: insights from multiomics profiling
This study aimed to investigate the prognostic impact of lymph node metastasis (LNM) on patients with colorectal cancer li...
Pro-survival roles for p21(Cip1/Waf1) in non-small cell lung cancer
Pro-survival roles for p21(Cip1/Waf1) in non-small cell lung cancer
Quiescence is reversible proliferative arrest. Multiple mechanisms regulate quiescence that are not fully understood. High...
阅读更多
format_indent_increase