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Both prolonged high-fat diet consumption and calorie restriction boost hepatic NAD+ metabolism in mice
Caloric intake dramatically influences the health and diseases in humans and animals. Excess energy intake often leads to ...
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Targeted Tumor Killing by Pomegranate Polyphenols: Pro-oxidant Role of a Classical Antioxidant
The most challenging task during the development of successful anti-cancer drugs lies in maintaining selective toxicity to...
DSS-induced acute colitis causes dysregulated tryptophan metabolism in brain: an involvement of gut microbiota
Inflammatory bowel disease (IBD) includes ulcerative colitis (UC) and Crohn's disease, characterized by intestinal structu...
Selenomethionine promotes ANXA2 phosphorylation for proliferation and protein synthesis of myoblasts and skeletal muscle growth
Selenium (Se) is an essential trace element for many living organisms. Plants and microorganisms take up several inorganic...
Sesamol promotes browning of white adipocytes through liver-adipose crosstalk signal of hepatic fibroblast growth factor 21
Obesity has been one of the major public health problems limiting life expectancy and is closely correlated with an increa...
Short-term flaxseed oil, rich in omega 3, protects mice against metabolic damage caused by high-fat diet, but not inflammation.
Available online 25 January 2023, 109270Author links open overlay panelAbstractIt is known that long-term high-fat diet (H...
Millet shell polyphenols ameliorate atherosclerosis development by suppressing foam cell formation
Grain polyphenols play an important role in the prevention and treatment of atherosclerosis. Phenolic components such as p...
Brown adipose tissue transcriptome unveils an important role of the Beta-alanine/alamandine receptor, MrgD, in metabolism
The renin-angiotensin system (RAS) is an endocrine system that provides a powerful mechanism for blood pressure control an...
Lycopene ameliorates DEHP exposure-induced renal pyroptosis through the Nrf2/Keap-1/NLRP3/Caspase-1 axis
Polymer materials are used to make food packaging, children's toys, feminine goods, and medical equipment [1] because of t...
Iron-frataxin involved in the protective effect of quercetin against alcohol-induced liver mitochondrial dysfunction
Data reported by the World Health Organization in 2018 showed that 5.1% of the global burden of diseases and 5.3% of death...
Hydroxytyrosol attenuates diquat-induced oxidative stress by activating Nrf2 pathway and modulating colonic microbiota in mice
Oxidative stress is characterized by a state where oxidation exceeds the antioxidant defenses due to the imbalance between...