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Disease phenotypic and outcome of very-early onset inflammatory bowel disease in Asian children: an understudied population
Introduction Worldwide between 8% and 10% of all inflammatory bowel disease (IBD) are diagnosed in childhood (<18 year...
Caregiver determinants and capacity for participation in constraint-induced movement therapy
1 Introduction Cerebral palsy (CP) is a group of neurological disorders that appear in infancy or early childhood that pe...
Perioperative comparison of whether the liver was lifted out of the abdominal cavity in Kasai surgery
1 Introduction Biliary atresia (BA) is an occlusive lesion affecting the intrahepatic and external bile ducts, leading to...
Case Report: White–Sutton syndrome and cannabidiol, an update on a reported patient with a successful response to off--label therapy
1 Introduction White–Sutton syndrome (WSS), also known as POGZ-Related Intellectual Disability Syndrome, represents a rar...
Guidance for shared decision-making regarding orchiectomy in individuals with differences of sex development due to 17-β-hydroxysteroid dehydrogenase type 3 deficiency
1 Introduction 17β-Hydroxysteroid dehydrogenase type 3 (17βHSD3) deficiency is a 46,XY difference/disorder of sex develop...
Tandem mass spectrometry in screening for inborn errors of metabolism: comprehensive bibliometric analysis
1 Introduction Tandem mass spectrometry (MS/MS) as a tool for detection of inborn errors of metabolism (IEM) was introduc...
Efficacy and safety of endoscopic fenestration for treating giant middle cranial fossa arachnoid cysts in pediatrics
Introduction Intracranial arachnoid cysts are predominantly congenital, benign, space-occupying lesions originating from ...
The clinical value of α-hydroxybutyrate dehydrogenase, cardiac troponin I, and B-type natriuretic peptide in perioperative diagnosis of heart failure in children with congenital heart disease
1 Introduction Congenital heart disease (CHD) is one of the most prevalent congenital anomalies in childhood and a leadin...
Use of CatBoost algorithm to identify the need for surgery in infants with necrotizing enterocolitis
1 Introduction Necrotizing enterocolitis (NEC) is an acute critical bowel disease commonly occurring in preterm infants. ...
Trend analysis of pediatric urolithiasis prevalence from 1990 to 2021 in the BRICS
The increasing epidemiological trend of pediatric urolithiasis over the past three decades has brought it to the forefront...
Case Report: Damaged external limb of montgomery T-tube in a child: a rare complication
Introduction Montgomery T-tubes (MT) enable patients with laryngotracheal stenosis to maintain airway patency and restore...
Plasma NMDAR autoantibody: a new biomarker for the diagnosis of Hirschsprung disease
Introduction Hirschsprung Disease (HSCR) is a congenital disorder due to lack of enteric neurons in the distal colon (1–3...
Outcomes of liver transplantation of hepatoblastoma: single-center data in mainland China
Introduction Hepatoblastoma (HB) is the most common primary liver cancer in infancy and childhood (1, 2), accounting for ...
Imaging characteristics of pediatric primary thymic lymphoepithelioma-like carcinoma: case reports of four children with a literature review
1 Introduction Thymic carcinoma can be divided into 12 subtypes, among which lymphoepithelioma-like carcinoma (LELC) is o...
Early caffeine therapy decreases bronchopulmonary dysplasia but might increase mortality in preterm infants? a systematic review and meta-analysis
1 Introduction Bronchopulmonary dysplasia (BPD) is a common respiratory complication in premature infants, particularly t...
Vitamin D status in children with COVID-19: does it affect the development of long COVID and its symptoms?
Introduction COVID-19, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), primarily affects the resp...
Extracellular vesicles and preterm infant diseases
1 Introduction Globally, approximately 15 million premature births occur annually, representing an estimated 11% of all d...
Research on the height of primary school students in Zhuzhou and analysis of influencing factors of short stature
1 Background Height serves as a primary indicator of physical growth in children, playing a crucial role in assessing the...
Correlation analysis between the severity of respiratory syncytial virus pneumonia and the expression levels of inflammatory cytokines in bronchoalveolar lavage fluid among infants and young children
1 Introduction Respiratory syncytial virus (RSV) is a single-stranded, negative-sense RNA virus and the predominant viral...
Curative effect of laparoscopic ureteral end-to-side anastomosis at the pelvic level for a duplex kidney in children
1 Introduction A “duplex kidney” (DK) is a congenital condition in which one kidney divides into an upper part and a lowe...
Monitoring lung recruitability during recruitment maneuvers in children with respiratory failure on ECMO using electrical impedance tomography: case report
Introduction Severe respiratory failure is associated with high morbidity and mortality especially when extracorporeal me...
Pleuropulmonary blastoma in a 3-year-old child with persistent fever: a case report
Highlights • This study highlights the diagnosis and treatment of PPB in a 3-year-old girl initially misdiagnosed with br...
Correlation and predictive value of oxygenation and oxygen saturation indices in extremely preterm infants: a prospective study
Introduction Neonatal Respiratory Distress Syndrome (RDS) is a common and significant cause of respiratory distress in ne...
Risk factors and incidence of unplanned re-operation after transumbilical single-hole laparoscopic appendectomy in children
1 Introduction Acute appendicitis (AA) is one of the most common emergency abdominal diseases in children, and surgical r...
Trametinib as a targeted treatment in cardiac and lymphatic presentations of Noonan syndrome
Introduction Noonan syndrome (NS) is a common autosomal dominant genetic disorder with multisystemic manifestations, incl...
Similarities and differences in the clinical features and management of primary lymphedema and kaposiform hemangioendothelioma associated with lymphedema in children
1 Introduction Lymphedema, an uncommon childhood vascular anomaly (VA), manifests as localized tissue swelling due to lym...
Association of preoperative cerebral oxygenation with concurrent neurobehavioral scores in term neonates with congenital heart disease compared to healthy controls
1 Introduction Children with congenital heart disease (CHD) are more susceptible to developmental delays (i.e., poorer ne...
The vicious spiral in Sudden Infant Death Syndrome
1 SIDS definition The first definition of Sudden Infant Death Syndrome (SIDS) was established during “The Second internat...
Treatment efficacy for infantile epileptic spasms syndrome in children with trisomy 21
Highlights • Epileptic spasms were the first recognized seizure type in all children with trisomy 21. • Children with tri...
Clinical characteristics and risk factors of Clostridioides difficile infection in children with diarrhoea
Introduction Clostridioides difficile (CD) is a specialized anaerobic, grossly gram-positive bacterium transmitted mainly...
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