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Omalizumab Implementation in Practice: Lessons Learned from the OUtMATCH Study
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Neuropsychiatric events related to montelukast and pranlukast in adults with asthma and rhinitis: A 10-year nationwide population-based study
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Striking a balance: new perspectives on homeostatic dendritic cell maturation
Striking a balance: new perspectives on homeostatic dendritic cell maturation
Dendritic cells (DCs) are crucial gatekeepers of the balance between immunity and tolerance. They exist in two functional ...
A B cell receptor variant confers evolutionary protection against pathogens
A B cell receptor variant confers evolutionary protection against pathogens
The G396R coding variant in IGHG1, which encodes membrane-bound IgG1 heavy chain, might have arisen within the Southeast A...
Author Correction: Type I IFNs promote cancer cell stemness by triggering the epigenetic regulator KDM1B
These authors jointly supervised this work: Ruggero De Maria, Ilio Vitale, Antonella Sistigu.Dipartimento di Medicina e Ch...
Genomic map of the cellular composition of the tumor microenvironment
Genomic map of the cellular composition of the tumor microenvironment
We integrated single-cell RNA-sequencing data to provide comprehensive profiles of the cellular composition of the tumor m...
Epigenetic tuning of PD-1 expression improves exhausted T cell function and viral control
Epigenetic tuning of PD-1 expression improves exhausted T cell function and viral control
PD-1 is a key negative regulator of CD8+ T cell activation and is highly expressed by exhausted T cells in cancer and chro...
Exploration and Validation of Immune and Therapeutic-Related Hub Genes in Aortic Valve Calcification and Carotid Atherosclerosis
Exploration and Validation of Immune and Therapeutic-Related Hub Genes in Aortic Valve Calcification and Carotid Atherosclerosis
Exploring and Validating of Immune and therapeutic-Related Hub Genes in Aortic Valve Calcification (AVC) and Carotid Ather...
Traditional Chinese Manual Therapy (Tuina) Improves Knee Osteoarthritis by Regulating Chondrocyte Autophagy and Apoptosis via the PI3K/AKT/mTOR Pathway: An in vivo Rat Experiment and Machine Learning Study
Traditional Chinese Manual Therapy (Tuina) Improves Knee Osteoarthritis by Regulating Chondrocyte Autophagy and Apoptosis via the PI3K/AKT/mTOR Pathway: An in vivo Rat Experiment and Machine Learning Study
To determine the effects of Tuina on a rat KOA model, focusing on the role of chondrocyte apoptosis and autophagy mechanisms
Inflammatory indices—Systemic Immune-Inflammation Index (SII) and Systemic Inflammatory Response Index (SIRI)—during Pregnancy and Associations with Gestational Diabetes Mellitus
Inflammatory indices—Systemic Immune-Inflammation Index (SII) and Systemic Inflammatory Response Index (SIRI)—during Pregnancy and Associations with Gestational Diabetes Mellitus
Exploring the associations between inflammatory indices during pregnancy and the development of gestational diabetes melli...
Corrigendum: Distribution characteristics of human herpes viruses in the lower respiratory tract and their impact on 30-day mortality in community-acquired pneumonia patients
Yadi Ding1†‡Guiming Liu1†Qiujing Li1†‡Lingqing Zou1‡Jingyi Dai1,2*‡Virasakdi Chongsuvivatwong3*‡1Department of Public Labo...
RfaH contributes to maximal colonization and full virulence of hypervirulent Klebsiella pneumoniae
1 IntroductionKlebsiella pneumoniae is a Gram-negative strain that frequently causes pulmonary infection, urinary tract in...
Intratumoral and fecal microbiota reveals microbial markers associated with gastric carcinogenesis
1 IntroductionGastric cancer (GC) ranks as the fifth most common cancer and the fourth leading cause of cancer deaths glob...
Editorial: Invasive fungal diseases: pathogen detection and diagnosis development
Advancement of medical care, such as the exponential expansion of the use of biologics, has resulted in an unprecedented n...
Case report: Personalized triple phage-antibiotic combination therapy to rescue necrotizing fasciitis caused by Panton-Valentine leukocidin-producing MRSA in a 12-year-old boy
IntroductionS. aureus is an important pathogen of necrotizing fasciitis, and MRSA isolates in particular have been reporte...
Revealing the association between East Asian oral microbiome and colorectal cancer through Mendelian randomization and multi-omics analysis
1 IntroductionColorectal cancer (CRC) remains one of the most prevalent cancer types globally. According to the 2020 GLOBO...
Gut microbiota and metabolomic profile changes play critical roles in tacrolimus-induced diabetes in rats
1 IntroductionTacrolimus (TAC) is a macrolide antibiotic produced by the soil fungus Streptomyces tsukubaensis. It is the ...
Recent advancement of novel marine fungi derived secondary metabolite fibrinolytic compound FGFC in biomedical applications: a review
1 IntroductionMarine sources have been continuously explored for biomedical approaches due to their richness of diverse na...
Emerging fatal gout disease in Chinese goslings linked to acute kidney injury induced by novel goose astrovirus infection
IntroductionA novel goose astrovirus (GAstV), which has caused substantial economic losses in the major goose-producing re...
SNX27:Retromer:ESCPE-1-mediated early endosomal tubulation impacts cytomegalovirus replication
1 IntroductionCytomegaloviruses (CMVs), large DNA viruses that belong to the beta-herpesvirus subfamily, cause asymptomati...
Circ_001653 alleviates sepsis associated-acute kidney injury by recruiting BUD13 to regulate KEAP1/NRF2/HO-1 signaling pathway
Circ_001653 alleviates sepsis associated-acute kidney injury by recruiting BUD13 to regulate KEAP1/NRF2/HO-1 signaling pathway
The kidney is exceptionally vulnerable during sepsis, often resulting in sepsis-associated acute kidney injury (SA-AKI), a...
ASIA syndrome after BNT162b2 vaccination: Is it a distinct rheumatoid arthritis phenotype?
ASIA syndrome after BNT162b2 vaccination: Is it a distinct rheumatoid arthritis phenotype?
Vaccines are an identified cause of autoimmune/inflammatory syndrome induced by adjuvants (ASIA syndrome). In this researc...
DMRT3-mediated lncRNA OIP5-AS1 promotes the pyroptosis of bronchial epithelial cells by binding with EIF4A3 to enhance YAP mRNA stability
DMRT3-mediated lncRNA OIP5-AS1 promotes the pyroptosis of bronchial epithelial cells by binding with EIF4A3 to enhance YAP mRNA stability
Asthma is featured by persistent airway inflammation. Long noncoding RNAs (lncRNAs) are reported to play critical roles in...
Improving adherence through collaboration and care coordination in the management of food allergies and asthma.
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A Streamlined Strategy for Basophil Activation Testing in a Multicenter Phase III Clinical Trial
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Mast cell BH4–serotonin metabolic network implicated in postoperative pain
Starkl et al. show that mast cells have a key role in the metabolic network that underlies postoperative pain and demonstr...
Using art and history to communicate immunology to a broad audience
Using art and history to communicate immunology to a broad audience
Francesca Di Rosa works on T cells and is committed to science outreach. Together with Adrian Hayday, she recently concept...
The complexity of immune evasion mechanisms throughout the metastatic cascade
The complexity of immune evasion mechanisms throughout the metastatic cascade
Metastasis, the spread of cancer from a primary site to distant organs, is an important challenge in oncology. This Review...
Exploration of Potential Therapeutic Targets of Shentong Zhuyu Decoction for Ankylosing Spondylitis Based on Network Pharmacology and Molecular Docking
Exploration of Potential Therapeutic Targets of Shentong Zhuyu Decoction for Ankylosing Spondylitis Based on Network Pharmacology and Molecular Docking
Exploring the potential active components and therapeutic targets of Shentong Zhuyu Decoction (SZD) in the treatment of an...
Unraveling Shared Diagnostic Biomarkers of Fibromyalgia in Ankylosing Spondylitis: Evidence from Comprehensive Bioinformatic Analysis and Experimental Validation
Unraveling Shared Diagnostic Biomarkers of Fibromyalgia in Ankylosing Spondylitis: Evidence from Comprehensive Bioinformatic Analysis and Experimental Validation
The shared hub genes in AS & FM; CETN3 & CACNA1E may become potential diagnostic biomarkers & therapeutic targ...
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