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The role of mitophagy-related genes in prognosis and immunotherapy of cutaneous melanoma: a comprehensive analysis based on single-cell RNA sequencing and machine learning
The role of mitophagy-related genes in prognosis and immunotherapy of cutaneous melanoma: a comprehensive analysis based on single-cell RNA sequencing and machine learning
Mitophagy, the selective degradation of mitochondria by autophagy, plays a crucial role in cancer progression and therapy ...
LAMP3-mediated epithelial-mesenchymal transition promotes the invasion and excessive proliferation of fibroblast-like synoviocytes in rheumatoid arthritis
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Impact of smoking on biological treatment response in patients from the German Severe Asthma (GAN) Registry
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Impact of parent-reported antibiotic allergies on paediatric Antimicrobial Stewardship Programs
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Relationships between Chronic Cough and Asthma Control and Quality-of-Life in Patients with Severe Asthma: A 6-Month Longitudinal Analysis
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Hazelnut oral immunotherapy desensitizes hazelnut but not other tree nut allergies (Nut CRACKER Study)
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Serum and urine eosinophil-derived neurotoxin (EDN) levels predict biologic response in severe asthma
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Comparative transcriptome analysis reveals a serotype-specific immune response in Nile tilapia (Oreochromis niloticus) infected with Streptococcus agalactiae
1 IntroductionThe aquaculture industry is continuously evolving towards more intensive cultivation systems. Although this ...
Genomic analysis of the main epidemiological lineages of Acinetobacter baumannii in Mexico
IntroductionAcinetobacter baumannii is a non-motile, aerobic Gram-negative bacterium that has become a major cause of heal...
Investigating the biological significance of the TCM principle “promoting urination to regulate bowel movements” through the influence of the intestinal microbiota and their metabolites on the renal-intestinal axis
Treatment methods in traditional Chinese medicine (TCM) are foundational to their theoretical, methodological, formulaic, ...
Insights and Considerations for “Higher Intraocular Levels of Inflammatory Factors are Related to Retinal Vascular and Neurodegeneration in Myopic Retinopathy” [Letter]
Insights and Considerations for “Higher Intraocular Levels of Inflammatory Factors are Related to Retinal Vascular and Neurodegeneration in Myopic Retinopathy” [Letter]
Letter for the article Higher Intraocular Levels of Inflammatory Factors are Related to Retinal Vascular and Neurodegenera...
IINS Vs CALLY Index: A Battle of Prognostic Value in NSCLC Patients Following Surgery
IINS Vs CALLY Index: A Battle of Prognostic Value in NSCLC Patients Following Surgery
assessing the inflammation-immunity-nutrition score and the high-sensitivity C-reactive protein-albumin-lymphocyte index i...
Chemerin-9 is neuroprotective in APP/PS1 transgenic mice by inhibiting NLRP3 inflammasome and promoting microglial clearance of Aβ
Chemerin-9 is neuroprotective in APP/PS1 transgenic mice by inhibiting NLRP3 inflammasome and promoting microglial clearance of Aβ
Alzheimer’s disease (AD) is a prevalent neurodegenerative disorder worldwide, and microglia are thought to play a ce...
Prognostic Value of the Preoperative Lymphocyte‐to‐Monocyte Ratio for Postoperative Adverse Events in Patients with Acute Type a Aortic Dissection
Prognostic Value of the Preoperative Lymphocyte‐to‐Monocyte Ratio for Postoperative Adverse Events in Patients with Acute Type a Aortic Dissection
Investigating prognostic value of preoperative lymphocyte‐to‐monocyte ratio for postoperative adverse events in patients w...
Skin Metabolic Signatures of Psoriasis and Psoriasis Concurrent with Metabolic Syndrome
Skin Metabolic Signatures of Psoriasis and Psoriasis Concurrent with Metabolic Syndrome
To provide new insights into the link between skin metabolism & psoriatic inflammation & the mechanism underlying ...
Development and Validation of a Diagnostic Model for Stanford Type B Aortic Dissection Based on Proteomic Profiling
Development and Validation of a Diagnostic Model for Stanford Type B Aortic Dissection Based on Proteomic Profiling
Validation of a diagnostic model for stanford type B aortic dissection based on proteomic profiling. Read more
Predicting Time to First Rejection Episode in Lung Transplant Patients Using a Comprehensive Multi-Indicator Model
Predicting Time to First Rejection Episode in Lung Transplant Patients Using a Comprehensive Multi-Indicator Model
The riskScore model effectively predicts time to first rejection episode in lung transplant recipients.
Shift work schedules alter immune cell regulation and accelerate cognitive impairment during aging
Shift work schedules alter immune cell regulation and accelerate cognitive impairment during aging
Disturbances of the sleep-wake cycle and other circadian rhythms typically precede the age-related deficits in learning an...
Association of the Monocyte to High-Density Lipoprotein Cholesterol Ratio and Neutrophil to High-Density Lipoprotein Cholesterol Ratio With the Severity of New-Onset Coronary Artery Disease
Association of the Monocyte to High-Density Lipoprotein Cholesterol Ratio and Neutrophil to High-Density Lipoprotein Cholesterol Ratio With the Severity of New-Onset Coronary Artery Disease
Exploring the correlation between MHR, NHR, and the severity of newly diagnosed coronary artery disease gauged by the Gens...
Explore Alteration of Lung and Gut Microbiota in a Murine Model of OVA-Induced Asthma Treated by CpG Oligodeoxynucleotides
Explore Alteration of Lung and Gut Microbiota in a Murine Model of OVA-Induced Asthma Treated by CpG Oligodeoxynucleotides
Mechanisms underlying the therapeutic effects of CpG-ODN in asthma treatment and identify potential beneficial symbiotic b...
Beyond the Norm: The emerging interplay of complement system and extracellular matrix in the tumor microenvironment
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Celiac disease, non-celiac wheat sensitivity, wheat allergy – clinical and diagnostic aspects
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Age-standardized incidence, prevalence, mortality rates and future projections of autoimmune diseases in China: a systematic analysis based on GBD 2021
Age-standardized incidence, prevalence, mortality rates and future projections of autoimmune diseases in China: a systematic analysis based on GBD 2021
This study assessed trends in age-standardized incidence (ASIR), prevalence (ASPR), and mortality rates (ASMR) per 100,000...
Effect of Epstein-Barr Virus infection on gene regulation in immune cells of patients with Immune-Mediated Diseases
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Maternal autoimmune systemic connective tissue disease and vasculitis and electrocardiographic findings in the offspring
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In perennial allergic rhinitis, RQLQ is improved similarly by Azelastine 0.15 and mometasone furoate
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Low-avidity T cells drive endogenous tumor immunity in mice and humans
Low-avidity T cells drive endogenous tumor immunity in mice and humans
T cells recognize neoepitope peptide-major histocompatibility complex class I on cancer cells. The strength (or avidity) o...
IRE1α–XBP1 safeguards hematopoietic stem and progenitor cells by restricting pro-leukemogenic gene programs
IRE1α–XBP1 safeguards hematopoietic stem and progenitor cells by restricting pro-leukemogenic gene programs
Hematopoietic stem cells must mitigate myriad stressors throughout their lifetime to ensure normal blood cell generation. ...
Interferon activation in bone marrow long-lived plasma cells in systemic lupus erythematosus
Highlights● ANA are found in lupus bone marrow.● SLE BM PC express a type I IFN gene signature.● BM PC subset distribution...
Interaction with IGF1 overrides ANXA2-mediated anti-inflammatory functions of IGFBP5 in vivo
1 IntroductionThe innate immune system is rapidly activated after infection, leading to elimination of pathogens and provi...
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