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Mucormycosis in 2023: an update on pathogenesis and management
Mucormycosis in 2023: an update on pathogenesis and management
Mucormycosis (MCR) is an emerging and frequently lethal fungal infection caused by the Mucorales family, with Rhizopus, Mu...
Characterization of gut microbiota profile in Iranian patients with bipolar disorder compared to healthy controls
Characterization of gut microbiota profile in Iranian patients with bipolar disorder compared to healthy controls
IntroductionThe human gut microbiota plays a crucial role in mental health through the gut-brain axis, impacting central n...
Cure of mycobacterium avium keratitis caused by trauma in elderly: case report
Cure of mycobacterium avium keratitis caused by trauma in elderly: case report
We report a case of Mycobacterium avium keratitis, first detected in the laboratory, which is from an 81-year-old female p...
Solved the enigma of pediatric severe acute hepatitis of unknown origin?
Solved the enigma of pediatric severe acute hepatitis of unknown origin?
Hepatitis is an inflammation of the liver whose etiology is very heterogeneous. The most common cause of hepatitis is vira...
The effect of temperature on dengue virus transmission by Aedes mosquitoes
The effect of temperature on dengue virus transmission by Aedes mosquitoes
Dengue is prevalent in tropical and subtropical regions. As an arbovirus disease, it is mainly transmitted by Aedes aegypt...
Malaria Vaccines: Progress to Date
Malaria Vaccines: Progress to Date
Malaria is a mosquito-borne disease caused by protozoan parasites of the genus Plasmodium. Despite significant declines in...
Mesenchymal Stem Cell-Derived Exosomes: A Novel Approach to Diabetes-Associated Cognitive Impairment
Mesenchymal Stem Cell-Derived Exosomes: A Novel Approach to Diabetes-Associated Cognitive Impairment
This article summarizes the positive influence of MSC-Exos on neuronal and synaptic regeneration in diabetes-related cogni...
Prognostic Value of Combined LMR and CEA Dynamic Monitoring in Postoperative Colorectal Cancer Patients
Prognostic Value of Combined LMR and CEA Dynamic Monitoring in Postoperative Colorectal Cancer Patients
Investigating the clinical significance of dynamic changes in the lymphocyte-to-monocyte ratio and neutrophil-lymphocyte r...
Vancomycin-Induced Liver Injury, DRESS, and HLA-A*32:01
Vancomycin-Induced Liver Injury, DRESS, and HLA-A*32:01
Available online 20 September 2023Author links open overlay panel, , , , , , , , , , , AbstractBackgroundIntravenous vanco...
Author Correction: The immunology of long COVID
Authors and AffiliationsDepartment of Immunology and Inflammation, Imperial College London, Hammersmith Hospital, London, ...
Characterization of pre-existing anti-PEG and anti-AGAL antibodies towards PRX-102 in patients with Fabry disease
Characterization of pre-existing anti-PEG and anti-AGAL antibodies towards PRX-102 in patients with Fabry disease
Polyethylene glycol (PEG)ylated drugs are used for medical treatment, since PEGylation either decreases drug clearance or/...
New insight into the role of fibroblasts in the epithelial immune microenvironment in the single-cell era
New insight into the role of fibroblasts in the epithelial immune microenvironment in the single-cell era
The skin is exposed to environmental challenges and contains heterogeneous cell populations such as epithelial cells, stro...
Extracellular vesicles as biomarkers for AIDS-associated non-Hodgkin lymphoma risk
Extracellular vesicles as biomarkers for AIDS-associated non-Hodgkin lymphoma risk
IntroductionExtracellular vesicles are membrane-bound structures secreted into the extracellular milieu by cells and can c...
Mitochondrial dysfunctions in T cells: focus on inflammatory bowel disease
Mitochondrial dysfunctions in T cells: focus on inflammatory bowel disease
Mitochondria has emerged as a critical ruler of metabolic reprogramming in immune responses and inflammation. In the conte...
Oxidation is an underappreciated post-translational modification in the regulation of immune responses associated with changes in phosphorylation
Oxidation is an underappreciated post-translational modification in the regulation of immune responses associated with changes in phosphorylation
Although macrophages are known to be affected by their redox status, oxidation is not yet a well-recognized post-translati...
Epigenetic targeting to enhance acute myeloid leukemia-directed immunotherapy
Epigenetic targeting to enhance acute myeloid leukemia-directed immunotherapy
AML is a malignant disease of hematopoietic progenitor cells with unsatisfactory treatment outcome, especially in patients...
Clinical features and mutational analysis of X-linked agammaglobulinemia patients in Malaysia
Clinical features and mutational analysis of X-linked agammaglobulinemia patients in Malaysia
BackgroundBruton’s tyrosine kinase (BTK) is a cytoplasmic protein involved in the B cell development. X-linked agammaglobu...
Human inborn errors of immunity associated with IRF4
Human inborn errors of immunity associated with IRF4
The transcription factor interferon regulatory factor 4 (IRF4) belongs to the IRF family and has several important functio...
Control of maternal Zika virus infection during pregnancy is associated with lower antibody titers in a macaque model
Control of maternal Zika virus infection during pregnancy is associated with lower antibody titers in a macaque model
IntroductionZika virus (ZIKV) infection during pregnancy results in a spectrum of birth defects and neurodevelopmental def...
Stilbenoid compounds inhibit NF-κB-mediated inflammatory responses in the Drosophila intestine
Stilbenoid compounds inhibit NF-κB-mediated inflammatory responses in the Drosophila intestine
IntroductionStilbenoid compounds have been described to have anti-inflammatory properties in animal models in vivo, and ha...
Attenuated IL-2 muteins leverage the TCR signal to enhance regulatory T cell homeostasis and response in vivo
Attenuated IL-2 muteins leverage the TCR signal to enhance regulatory T cell homeostasis and response in vivo
Interleukin-2 (IL-2), along with T-cell receptor (TCR) signaling, are required to control regulatory T cell (Treg) homeost...
Homologs of bacterial heat-labile enterotoxin subunit A contribute to development, stress response, and virulence in filamentous entomopathogenic fungus Beauveria bassiana
Homologs of bacterial heat-labile enterotoxin subunit A contribute to development, stress response, and virulence in filamentous entomopathogenic fungus Beauveria bassiana
IntroductionEnterotoxigenic bacteria commonly excrete heat-labile enterotoxins (LT) as virulence factors that consist of o...
Cardiovascular impairment in Shiga-toxin-2-induced experimental hemolytic–uremic syndrome: a pilot study
Cardiovascular impairment in Shiga-toxin-2-induced experimental hemolytic–uremic syndrome: a pilot study
IntroductionHemolytic–uremic syndrome (HUS) can occur as a systemic complication of infection with Shiga toxin (Stx)-produ...
ß1-adrenergic blockers preserve neuromuscular function by inhibiting the production of extracellular traps during systemic inflammation in mice
ß1-adrenergic blockers preserve neuromuscular function by inhibiting the production of extracellular traps during systemic inflammation in mice
Severe inflammation via innate immune system activation causes organ dysfunction. Among these, the central nervous system ...
Flow cytometric analysis of innate lymphoid cells: challenges and solutions
Flow cytometric analysis of innate lymphoid cells: challenges and solutions
IntroductionThe three groups of helper innate lymphoid cells (ILCs), namely ILC1, ILC2 and ILC3, have been identified by f...
M2 macrophage inhibits the antitumor effects of Lenvatinib on intrahepatic cholangiocarcinoma
M2 macrophage inhibits the antitumor effects of Lenvatinib on intrahepatic cholangiocarcinoma
Background and objectivesThe relationship between the tumor microenvironment and the network of key signaling pathways in ...
Case Report: High-dose steroid and IVIG successful treatment in a case of COVID-19-associated autoimmune encephalitis: a literature review
Case Report: High-dose steroid and IVIG successful treatment in a case of COVID-19-associated autoimmune encephalitis: a literature review
Autoimmune encephalitis is a rare but critical complication of COVID-19. The management of COVID-19-associated autoimmune ...
The role of DC-SIGN as a trans-receptor in infection by MERS-CoV
The role of DC-SIGN as a trans-receptor in infection by MERS-CoV
DC-SIGN is a C-type lectin expressed in myeloid cells such as immature dendritic cells and macrophages. Through glycan rec...
Evolutionary, comparative, and functional analyses of STATs and regulation of the JAK-STAT pathway in lumpfish upon bacterial and poly(I:C) exposure
Evolutionary, comparative, and functional analyses of STATs and regulation of the JAK-STAT pathway in lumpfish upon bacterial and poly(I:C) exposure
BackgroundThe Janus kinase/signal transducers and activators of transcription (JAK-STAT) system regulates several biologic...
Staphylococcus cohnii infection diagnosed by metagenomic next generation sequencing in a patient on hemodialysis with cirrhotic ascites: a case report
Staphylococcus cohnii infection diagnosed by metagenomic next generation sequencing in a patient on hemodialysis with cirrhotic ascites: a case report
BackgroundPatients with spontaneous bacterial peritonitis (SBP) often just receive empirical antibiotic therapy, as pathog...
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