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Immune Response to SARS-CoV-2 Infections in Children with Secondary Immunodeficiencies
Immune Response to SARS-CoV-2 Infections in Children with Secondary Immunodeficiencies
It is a matter of research, whether children with immunodeficiencies are able to generate an effective immune response to ...
Lymphoma as an Exclusion Criteria for CVID Diagnosis Revisited
Lymphoma as an Exclusion Criteria for CVID Diagnosis Revisited
Hypogammaglobulinemia in a context of lymphoma is usually considered as secondary and prior lymphoma remains an exclusion ...
Platelet-to-lymphocyte ratio at 24h after thrombolysis is a prognostic marker in acute ischemic stroke patients
Platelet-to-lymphocyte ratio at 24h after thrombolysis is a prognostic marker in acute ischemic stroke patients
BackgroundThe changes in the platelet-to-lymphocyte ratio (PLR) before and after recombinant tissue plasminogen activator ...
POP1 inhibits MSU-induced inflammasome activation and ameliorates gout
POP1 inhibits MSU-induced inflammasome activation and ameliorates gout
Canonical inflammasomes are innate immune protein scaffolds that enable the activation of inflammatory caspase-1, and subs...
Severity of SARS-CoV-2 infection is associated with high numbers of alveolar mast cells and their degranulation
Severity of SARS-CoV-2 infection is associated with high numbers of alveolar mast cells and their degranulation
BackgroundThe systemic inflammatory response post-SARS-CoV-2 infection increases pro-inflammatory cytokine production, mul...
Construction of a nomogram to predict the survival of metastatic gastric cancer patients that received immunotherapy
Construction of a nomogram to predict the survival of metastatic gastric cancer patients that received immunotherapy
BackgroundImmunotherapy has shown promising results for metastatic gastric cancer (MGC) patients. Nevertheless, not all pa...
Organoids and microphysiological systems: Promising models for accelerating AAV gene therapy studies
Organoids and microphysiological systems: Promising models for accelerating AAV gene therapy studies
The FDA has predicted that at least 10-20 gene therapy products will be approved by 2025. The surge in the development of ...
Teleost fish IgM+ plasma-like cells possess IgM-secreting, phagocytic, and antigen-presenting capacities
Teleost fish IgM+ plasma-like cells possess IgM-secreting, phagocytic, and antigen-presenting capacities
Plasma cells are terminally differentiated antibody-secreting B lymphocytes that contribute to humoral immunity by produci...
Low baseline IFN-γ response could predict hospitalization in COVID-19 patients
Low baseline IFN-γ response could predict hospitalization in COVID-19 patients
The SARS-CoV-2 infection has spread rapidly around the world causing millions of deaths. Several treatments can reduce mor...
Communication is key: Innate immune cells regulate host protection to helminths
Communication is key: Innate immune cells regulate host protection to helminths
Parasitic helminth infections remain a significant global health issue and are responsible for devastating morbidity and e...
Synthetic MRI in the detection and quantitative evaluation of sacroiliac joint lesions in axial spondyloarthritis
Synthetic MRI in the detection and quantitative evaluation of sacroiliac joint lesions in axial spondyloarthritis
ObjectiveOur primary objective was to verify the hypothesis that synthetic magnetic resonance imaging (MRI) is similar to ...
Immunological characterization and function analysis of L-type lectin from spotted knifejaw, Oplegnathus punctatus
Immunological characterization and function analysis of L-type lectin from spotted knifejaw, Oplegnathus punctatus
Lily-type lectin (LTL) plays significant roles in innate immune response against pathogen infection. LTL in animals and pl...
CAR-T manufactured from frozen PBMC yield efficient function with prolonged in vitro production
CAR-T manufactured from frozen PBMC yield efficient function with prolonged in vitro production
Chimeric antigen receptor (CAR)-T cells are engineered to identify and eliminate cells expressing a target antigen. Curren...
Immunogenic cell death related risk model to delineate ferroptosis pathway and predict immunotherapy response of patients with GBM
Immunogenic cell death related risk model to delineate ferroptosis pathway and predict immunotherapy response of patients with GBM
Immunogenic cell death (ICD) is a type of cell death that leads to the regulation and activation of the immune response, w...
The potential risk factors of early-onset post-stroke depression from immuno-inflammatory perspective
The potential risk factors of early-onset post-stroke depression from immuno-inflammatory perspective
BackgroundMounting evidence strongly uncovered that peripheral immuno-inflammatory response induced by acute stroke is ass...
Clinical validation of visual LAMP and qLAMP assays for the rapid detection of Toxoplasma gondii
Clinical validation of visual LAMP and qLAMP assays for the rapid detection of Toxoplasma gondii
Humans are exposed to Toxoplasma gondii infection as pet cats gradually become family members and represent an increasing ...
Non-capsular based immunization approaches to prevent Streptococcus pneumoniae infection
Non-capsular based immunization approaches to prevent Streptococcus pneumoniae infection
Streptococcus pneumoniae is a Gram-positive bacterium and the leading cause of bacterial pneumonia in children and the eld...
The IL-20RB receptor and the IL-20 signaling pathway in regulating host defense in oral mucosal candidiasis
The IL-20RB receptor and the IL-20 signaling pathway in regulating host defense in oral mucosal candidiasis
Pseudomembranous candidiasis (thrush), erythematous candidiasis, and fungal esophagitis are infections of the barrier muco...
Vaccines, Vol. 10, Pages 1603: The Deletion of US3 Gene of Pseudorabies Virus (PRV) ΔgE/TK Strain Induces Increased Immunogenicity in Mice
Vaccines, Vol. 10, Pages 1603: The Deletion of US3 Gene of Pseudorabies Virus (PRV) ΔgE/TK Strain Induces Increased Immunogenicity in Mice
Re-emerging pseudorabies (PR) caused by pseudorabies virus (PRV) variant has been prevailing among immunized herds in Chin...
Vaccines, Vol. 10, Pages 1608: Association between Adverse Reactions and Humoral Immune Response No Longer Detectable after BNT162b2 Booster Vaccination
Vaccines, Vol. 10, Pages 1608: Association between Adverse Reactions and Humoral Immune Response No Longer Detectable after BNT162b2 Booster Vaccination
In a previous study, we described a highly significant association between reactogenicity and SARS-CoV-2 RBD IgG titers an...
Vaccines, Vol. 10, Pages 1610: Influenza Vaccine Uptake in the United States before and during the COVID-19 Pandemic
Vaccines, Vol. 10, Pages 1610: Influenza Vaccine Uptake in the United States before and during the COVID-19 Pandemic
The COVID-19 pandemic, along with disruptions to routine medical care, brought renewed urgency to public health messaging ...