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Hernias of the Cerebellum
Hernias of the Cerebellum
The present Cerebellar Classic highlights a paper published in 1908 by the American pathologist Simeon Burt Wolbach (1880&...
Noradrenergic Pathway to the Cerebellum: the Study Must Go On
Noradrenergic Pathway to the Cerebellum: the Study Must Go On
In 1967, Andén, Fuxe, and Ungerstedt demonstrated the presence of monoamine-containing fibers in the rat cerebellum. ...
The Discovery of the Monoaminergic Innervation of the Cerebellum: Convergence of Divergent and Point-to-Point Systems
The Discovery of the Monoaminergic Innervation of the Cerebellum: Convergence of Divergent and Point-to-Point Systems
This Cerebellar Classic highlights the landmark discovery of the innervation of the cerebellar cortex and cerebellar nucle...
Cerebellar Prediction and Feeding Behaviour
Cerebellar Prediction and Feeding Behaviour
Given the importance of the cerebellum in controlling movements, it might be expected that its main role in eating would b...
Does Head Tremor Predict Postural Instability After Bilateral Thalamic Stimulation in Essential Tremor?
Does Head Tremor Predict Postural Instability After Bilateral Thalamic Stimulation in Essential Tremor?
Essential tremor (ET) may present with head tremor (HT), of presumed cerebellar nature. Deep brain stimulation (DBS) targe...
Analysis of the Clinical Features and Imaging Findings of Pontocerebellar Hypoplasia Type 2D Caused by Mutations in SEPSECS Gene
Analysis of the Clinical Features and Imaging Findings of Pontocerebellar Hypoplasia Type 2D Caused by Mutations in SEPSECS Gene
Pontocerebellar hypoplasia type 2D (PCH2D) caused by SEPSECS gene mutations is very rare and only described in a few case ...
Visuomotor Adaptation Deficits in Patients with Essential Tremor
Visuomotor Adaptation Deficits in Patients with Essential Tremor
Essential tremor (ET) is a progressive movement disorder whose pathophysiology is not fully understood. Current evidence s...
Clinical and Genetic Features of Multiplex Families with Multiple System Atrophy and Parkinson’s Disease
Clinical and Genetic Features of Multiplex Families with Multiple System Atrophy and Parkinson’s Disease
While multiple system atrophy (MSA) has been considered a sporadic disease, there were previously reported multiplex famil...
The C-Terminal Cross-linked Telopeptide of Type I Collagen (CTX-I) as a Potential Cardiomyopathy Biomarker in Friedreich Ataxia Patients
The C-Terminal Cross-linked Telopeptide of Type I Collagen (CTX-I) as a Potential Cardiomyopathy Biomarker in Friedreich Ataxia Patients
Friedreich’s ataxia (FRDA) is the most common inherited recessive ataxia. Cardiomyopathy (CM) with myocardial hypert...
Physiological Recordings of the Cerebellum in Movement Disorders
Physiological Recordings of the Cerebellum in Movement Disorders
The cerebellum plays an important role in movement disorders, specifically in symptoms of ataxia, tremor, and dystonia. Un...
Clinical Features and Neuroimaging Findings of Neuropil Antibody–Positive Idiopathic Sporadic Ataxia of Unknown Etiology
Clinical Features and Neuroimaging Findings of Neuropil Antibody–Positive Idiopathic Sporadic Ataxia of Unknown Etiology
Idiopathic sporadic ataxia (ISA) is the clinical term for nonfamilial ataxia with adult-onset and a slowly progressive cou...
Changes in Corticospinal Excitability and Motor Control During Cerebellar Transcranial Direct Current Stimulation in Healthy Individuals
Changes in Corticospinal Excitability and Motor Control During Cerebellar Transcranial Direct Current Stimulation in Healthy Individuals
Cerebellar transcranial direct current stimulation (ctDCS) modulates the primary motor cortex (M1) via cerebellar brain in...
Oxytocin Receptor in Cerebellar Purkinje Cells Does Not Engage in Autism-Related Behaviors
Oxytocin Receptor in Cerebellar Purkinje Cells Does Not Engage in Autism-Related Behaviors
The classical motor center cerebellum is one of the most consistent structures of abnormality in autism spectrum disorders...
The Effect of Cerebellar rTMS on Modulating Motor Dysfunction in Neurological Disorders: a Systematic Review
The Effect of Cerebellar rTMS on Modulating Motor Dysfunction in Neurological Disorders: a Systematic Review
The effectiveness of cerebellar repetitive transcranial magnetic stimulation (rTMS) on motor dysfunction in patients with ...
Ataxia Rating Scales Reveal Increased Scores in Very Preterm Born 5–6-Year-Old Preschool Children and Young Adults
Ataxia Rating Scales Reveal Increased Scores in Very Preterm Born 5–6-Year-Old Preschool Children and Young Adults
The aim of this study is to investigate whether scores in ataxia rating scales (ARS) are different in very preterm (VP) pr...
Effects of Cerebellar Transcranial Direct Current Stimulation in Patients with Stroke: a Systematic Review
Effects of Cerebellar Transcranial Direct Current Stimulation in Patients with Stroke: a Systematic Review
The cerebellum is involved in regulating motor, affective, and cognitive processes. It is a promising target for transcran...
ClearSpeechTogether: a Rater Blinded, Single, Controlled Feasibility Study of Speech Intervention for People with Progressive Ataxia
ClearSpeechTogether: a Rater Blinded, Single, Controlled Feasibility Study of Speech Intervention for People with Progressive Ataxia
Progressive ataxias frequently lead to speech disorders and consequently impact on communication participation and psychos...
Voxel-Based Morphometry and Relaxometry Demonstrate Macro- and Microstructural Damages in Spinocerebellar Ataxia Type 3
Voxel-Based Morphometry and Relaxometry Demonstrate Macro- and Microstructural Damages in Spinocerebellar Ataxia Type 3
Spinocerebellar ataxia type 3/Machado-Joseph disease (SCA3/MJD) is the most common SCA worldwide and comprises about 70% o...
Magnetic Resonance T1w/T2w Ratio in the Putamen and Cerebellum as a Marker of Cognitive Impairment in MSA: a Longitudinal Study
Magnetic Resonance T1w/T2w Ratio in the Putamen and Cerebellum as a Marker of Cognitive Impairment in MSA: a Longitudinal Study
The exact pathophysiology of cognitive impairment in multiple system atrophy (MSA) is unclear. In our longitudinal study, ...
A Review on the Clinical Diagnosis of Multiple System Atrophy
A Review on the Clinical Diagnosis of Multiple System Atrophy
Multiple system atrophy (MSA) is a rare, adult-onset, progressive neurodegenerative disorder with major diagnostic challen...
A De Novo HECW2 Variant in a Patient with Acetazolamide-Responsive Episodic Ataxia
A De Novo HECW2 Variant in a Patient with Acetazolamide-Responsive Episodic Ataxia
To the best of our knowledge, this is the first case to address episodic ataxia (EA) as a possible phenotypic feature of H...
Ataxia Myoclonus Syndrome in Mild Acute COVID-19 Infection
Ataxia Myoclonus Syndrome in Mild Acute COVID-19 Infection
Ethics Approval The authors confirm that we have read the Journal’s...
TSEN54 Gene-Related Pontocerebellar-Hypoplasia and Role of Prenatal MR Imaging: Besides the Common Posterior Fossa Cystic Malformations
TSEN54 Gene-Related Pontocerebellar-Hypoplasia and Role of Prenatal MR Imaging: Besides the Common Posterior Fossa Cystic Malformations
Pontocerebellar-hypoplasia (PCH) related to TSEN54-gene mutation, a rare autosomal recessive disorder, can be associated w...
The S-Factor, a New Measure of Disease Severity in Spinocerebellar Ataxia: Findings and Implications
The S-Factor, a New Measure of Disease Severity in Spinocerebellar Ataxia: Findings and Implications
Spinocerebellar ataxias (SCAs) are progressive neurodegenerative disorders, but there is no metric that predicts disease s...
Ferdinando Rossi Lecture: the Cerebellar Cognitive Affective Syndrome—Implications and Future Directions
Ferdinando Rossi Lecture: the Cerebellar Cognitive Affective Syndrome—Implications and Future Directions
The notion that the cerebellum is devoted exclusively to motor control has been replaced by a more sophisticated understan...
Altered Effective Connectivity Among the Cerebellum and Cerebrum in Patients with Major Depressive Disorder Using Multisite Resting-State fMRI
Altered Effective Connectivity Among the Cerebellum and Cerebrum in Patients with Major Depressive Disorder Using Multisite Resting-State fMRI
Major depressive disorder (MDD) is a serious and widespread psychiatric disorder. Previous studies mainly focused on cereb...