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Systems Analysis of Human Innate Immunity in COVID-19
Recent developments in sequencing technologies, the computer and data sciences, as well as increasingly high-throughput im...
From Amish farm dust to bacterial lysates: The long and winding road to protection from allergic disease
Volume 68, July 2023, 101779Author links open overlay panelHighlights•Protective mechanisms from natural microbe-rich envi...
Targeting dendritic cells to advance cross-presentation and vaccination outcomes
Volume 68, July 2023, 101762Author links open overlay panel, , , AbstractDendritic cells (DCs) are a complex network of sp...
The biogenesis of the immunopeptidome
AbbreviationsAPPAntigen processing and presentationAPCAntigen-presenting cellsLC-MS/MSLiquid chromatography and tandem mas...
Introduction to the Special Issue: Nutrition, microbiota and immunity
Volume 67, May 2023, 101767Author links open overlay panelLaurence Zitvogel a b c, Guido Kroemer d e f g hShow morePreviou...
Mechanisms of climate change and related air pollution on the immune system leading to allergic disease and asthma
Available online 25 April 2023, 101765Author links open overlay panel, , , Highlights•Fossil fuels are increasing greenhou...
Innate immune effectors in cancer
Volume 67, May 2023, 101760Author links open overlay panelLorenzo Moretta, Paola VaccaShow morePrevious article in issueNe...
Cross-presentation by the others
AbbreviationsAPCAntigen Presenting CellAtgAutophagy Related GenesBatf3Basic Leucine Zipper ATF-Like Transcription Factor 3...
Genetics of Inborn Errors of Immunity in highly consanguineous Middle Eastern and North African populations
Consanguineous marriages in Middle Eastern and North African (MENA) countries are deeply-rooted tradition and highly preva...
Immunity to pathogenic fungi in the eye
Volume 67, May 2023, 101753Author links open overlay panel, , , , , , AbstractFusarium, Aspergillus and Candida are import...
Somatic mosaicism in inborn errors of immunity: Current knowledge, challenges, and future perspectives
Inborn errors of immunity (IEI) are a diverse group of monogenic disorders of the immune system due to germline variants i...
Chitinases and chitinase-like proteins in asthma
Volume 67, May 2023, 101759Author links open overlay panel, , , AbstractDespite the lack of endogenous chitin synthesis, m...
The peptide woods are lovely, dark and deep: Hunting for novel cancer antigens
Volume 67, May 2023, 101758Author links open overlay panel, , , Highlights•Review of novel antigen types in cancer that ca...
Western diet influences on microbiome and carcinogenesis
The intestinal microbiota composition and associated bioactivities are sensitive to various modifier cues such as stress, ...
Integrating immunopeptidome analysis for the design and development of cancer vaccines
The repertoire of naturally presented peptides within the MHC (major histocompatibility complex) or HLA (human leukocyte a...
Exploiting antifungal immunity in the clinical context
PJPPneumocystis jirovecii pneumoniaHSCThematopoietic stem cell transplantationSOTsolid organ transplantationSNPsingle nucl...
Immunoglobulins at the interface of the gut mycobiota and anti-fungal immunity
Volume 67, May 2023, 101757Author links open overlay panel, , AbstractThe dynamic and complex community of microbes that c...
Future indications and clinical management for fecal microbiota transplantation (FMT) in immuno-oncology
The gut microbiota has rapidly emerged as one of the “hallmarks of cancers” and a key contributor to cancer immunotherapy....
TREM2: A new player in the tumor microenvironment
Volume 67, May 2023, 101739Author links open overlay panel, , , AbstractTREM2 is a myeloid cell receptor that has been ext...
What fungal CNS infections can teach us about neuroimmunology and CNS-specific immunity
Volume 67, May 2023, 101751Author links open overlay panelAbstractImmunity to fungal infections of the central nervous sys...
Microbial metabolites and immunotherapy: Basic rationale and clinical indications
Volume 67, May 2023, 101755Author links open overlay panel, AbstractOur microbiota has a critical role in shaping host imm...
Viral- and tumor-reactive natural killer cells
Volume 67, May 2023, 101749Author links open overlay panel, AbstractWhen we can understand what natural killer (NK) cells ...
“Under Pressure” – How fungi evade, exploit, and modulate cells of the innate immune system
The human immune system uses an arsenal of effector mechanisms to prevent and counteract infections. Yet, some fungal spec...
Human thymus in health and disease: Recent advances in diagnosis and biology
The thymus is the crucial tissue where thymocytes develop from hematopoietic precursors that originate from the bone marro...
Correcting inborn errors of immunity: From viral mediated gene addition to gene editing
AbbreviationsγRVγ-Retroviral Vector;AAVAdeno-associated viral vectorAAVS1Adeno-associated virus site 1ADAAdenosine deamina...
Seminars in immunology special issue: Nutrition, microbiota and immunity The unexplored microbes in health and disease
Volume 66, March 2023, 101735Author links open overlay panel, AbstractFunctional characterization of the microbiome’s infl...
Impact of dietary carbohydrate restriction on the pathobiology of Hepatocellular Carcinoma: The gut-liver axis and beyond
Despite decades of fiercely competitive research and colossal financial investments, the majority of patients with advance...
A major mechanism for immunomodulation: Dietary fibres and acid metabolites
AbbreviationsSCFAsShort-chain fatty acidsDPDegree of polymerizationIBDInflammatory bowel diseaseDSSDextran sulfate sodiumC...
Immunity to fungi: Editorial overview
Volume 66, March 2023, 101734Author links open overlay panelJanet A. Willment, Gordon D. BrownShow morePrevious article in...
Immunity to fungi in the lung
Volume 66, March 2023, 101728Author links open overlay panel, , , , Highlights•Lifelong human exposure to inhaled fungi an...