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NGS data analysis for molecular diagnosis of Inborn Errors of Immunity
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The role of sialoglycans in modulating dendritic cell function and tumour immunity
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Sialic acid and Siglec receptors in tumor immunity and immunotherapy
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ABO blood groups and galectins: Implications in transfusion medicine and innate immunity
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Shaping hematopoietic cell ecosystems through galectin-glycan interactions
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The role of glycans in health and disease: Regulators of the interaction between gut microbiota and host immune system
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High-throughput N-glycan analysis in aging and inflammaging: State of the art and future directions
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Siglecs as modulators of macrophage phenotype and function
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The world’s largest experiment in human immunology
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The origins, manifestations, and potential treatments of allergic disorders
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Durability of immune responses to SARS-CoV-2 infection and vaccination
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Early life microbiome influences on development of the mucosal innate immune system
Early life microbiome influences on development of the mucosal innate immune system
The gut microbiota is well known to possess immunomodulatory capacities, influencing a multitude of cellular signalling pa...
Introduction to the Special Issue: Pyroptosis in Immunity and Inflammation
Introduction to the Special Issue: Pyroptosis in Immunity and Inflammation
Cookies are used by this site. Cookie SettingsAll content on this site: Copyright © 2024 Elsevier B.V., its licensors, an...
B cell clonality in cancer
B cell clonality in cancer
Mechanically, adaptive immunity is well positioned to recognize and destroy tumor cells. It is the successful antigen-spec...
Systems biology of B cells in COVID-19
Systems biology of B cells in COVID-19
Since the beginning of the COVID-19 pandemic the elicitation and persistence of antibody-mediated protection has been a pr...
Systems analysis of innate and adaptive immunity in Long COVID
Systems analysis of innate and adaptive immunity in Long COVID
Long COVID (LC), also referred to as post-acute sequelae of SARS-CoV-2 infection (PASC) or post-COVID condition (PCC), is ...
Introduction to the special issue: B cells in cancer immunosurveillance
Introduction to the special issue: B cells in cancer immunosurveillance
Cookies are used by this site. Cookie SettingsAll content on this site: Copyright © 2024 Elsevier B.V., its licensors, an...
Toolkit for mapping the clonal landscape of tumor-infiltrating B cells
Toolkit for mapping the clonal landscape of tumor-infiltrating B cells
Resolving intratumoral B cells and IG-producing plasma cell content is critical for our understanding of tumor-immunity in...
Type I and type III interferons: From basic biology and genetics to clinical development for COVID-19 and beyond
Type I and type III interferons: From basic biology and genetics to clinical development for COVID-19 and beyond
Type I interferons (IFNs) constitute a major antiviral defense system of the body. They were discovered over 60 years ago ...
To die or not to die: Gasdermins in intestinal health and disease
To die or not to die: Gasdermins in intestinal health and disease
The first member of the gasdermin family was identified in the upper gastrointestinal tract in 2000 [1]. Up until now, the...
Gut-liver axis: Pathophysiological concepts and medical perspective in chronic liver diseases
Gut-liver axis: Pathophysiological concepts and medical perspective in chronic liver diseases
AhRAryl hydrocarbon receptorASHalcoholic steatohepatitisACLFacute-on-chronic-liver-failureASBTApical Sodium-dependent BA T...
Antigen cross-presentation by dendritic cells: A critical axis in cancer immunotherapy
Antigen cross-presentation by dendritic cells: A critical axis in cancer immunotherapy
Volume 71, February 2024, 101848Author links open overlay panel, AbstractDendritic cells (DCs) are professional antigen-pr...
Regulated cell death in neutrophils: From apoptosis to NETosis and pyroptosis
Regulated cell death in neutrophils: From apoptosis to NETosis and pyroptosis
Volume 70, November 2023, 101849Author links open overlay panel, , , AbstractNeutrophils are among the most abundant immun...
Regulatory T cells in allergic inflammation
Regulatory T cells in allergic inflammation
APCsAntigen-presenting cellsAT2Type II alveolar cellsαVβ8alpha-V:beta-8 integrinα4β7Alpha 4 beta 7 integrinCCR6C-C Motif C...
Chemical modulation of gasdermin D activity: Therapeutic implications and consequences
Chemical modulation of gasdermin D activity: Therapeutic implications and consequences
Volume 70, November 2023, 101845Author links open overlay panel, Highlights•The gasdermin family of proteins are terminal ...
The epithelial barrier: The gateway to allergic, autoimmune, and metabolic diseases and chronic neuropsychiatric conditions
The epithelial barrier: The gateway to allergic, autoimmune, and metabolic diseases and chronic neuropsychiatric conditions
KeywordsAllergyAutoimmune diseasesBarrier dysfunctionEpithelitisEpithelial barrier theoryLungsMetabolic diseasesMicrobiota...
The noncanonical inflammasome-induced pyroptosis and septic shock
The noncanonical inflammasome-induced pyroptosis and septic shock
AbbreviationAAK1AP2 Associated Kinase 1AOAHAcyloxyacyl hydrolaseCARDCaspase recruitment and activation domaincGASCyclic GM...
The immunology and cell biology of T cell aging
The immunology and cell biology of T cell aging
Volume 70, November 2023, 101843Author links open overlay panelJörg J. Goronzy, Nan-ping WengShow morePrevious article in ...
Beyond youth: Understanding CAR T cell fitness in the context of immunological aging
Beyond youth: Understanding CAR T cell fitness in the context of immunological aging
Volume 70, November 2023, 101840Author links open overlay panel, , , AbstractPopulation aging, a pervasive global demograp...
Baseline immune states (BIS) associated with vaccine responsiveness and factors that shape the BIS
Baseline immune states (BIS) associated with vaccine responsiveness and factors that shape the BIS
Vaccines are among the greatest inventions in medicine, leading to the elimination or control of numerous diseases, includ...
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