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Correction: Indobufen versus aspirin in acute ischaemic stroke (INSURE): rationale and design of a multicentre randomised trial
Correction: Indobufen versus aspirin in acute ischaemic stroke (INSURE): rationale and design of a multicentre randomised trial
Pan Y, Meng X, Chen W, et al. Indobufen versus aspirin in acute ischaemic stroke (INSURE): rationale and design of a multi...
Antithrombotic therapy in patients with COVID-19: indications, pharmacotherapy and controversy
Antithrombotic therapy in patients with COVID-19: indications, pharmacotherapy and controversy
Hypercoagulability associated with COVID-19 infection increases risks for either venous or arterial thrombotic events (ATE...
Arteriolosclerosis differs from venular collagenosis in relation to cerebrovascular parenchymal damages: an autopsy-based study
Arteriolosclerosis differs from venular collagenosis in relation to cerebrovascular parenchymal damages: an autopsy-based study
WHAT IS ALREADY KNOWN ON THIS TOPICHOW THIS STUDY MIGHT AFFECT RESEARCH, PRACTICE OR POLICYIntroductionCerebrovascular par...
Association between statin therapy and the risk of stroke in patients with moyamoya disease: a nationwide cohort study
Association between statin therapy and the risk of stroke in patients with moyamoya disease: a nationwide cohort study
IntroductionMoyamoya disease (MMD) is a rare cerebrovascular disease characterised by progressive non-atherosclerotic sten...
Differences in left and right carotid plaque vulnerability in patients with bilateral carotid plaques: a CARE-II study
Differences in left and right carotid plaque vulnerability in patients with bilateral carotid plaques: a CARE-II study
WHAT IS ALREADY KNOWN ON THIS TOPICHOW THIS STUDY MIGHT AFFECT RESEARCH, PRACTICE OR POLICYBackgroundAtherosclerosis occur...
Acute right insular ischaemic lesions and poststroke left ventricular dysfunction
Acute right insular ischaemic lesions and poststroke left ventricular dysfunction
WHAT IS ALREADY KNOWN ON THIS TOPICMyocardial injury is related to acute ischaemic stroke even without prior cardiac disea...
Angioarchitecture and prognosis of pediatric intracranial pial arteriovenous fistula
Angioarchitecture and prognosis of pediatric intracranial pial arteriovenous fistula
IntroductionPial arteriovenous fistula (PAVF) is a rare intracranial vascular disease defined as a direct pathological con...
Mechanical thrombectomy with combined stent retriever and contact aspiration versus stent retriever alone for acute large vessel occlusion: data from ANGEL-ACT registry
Mechanical thrombectomy with combined stent retriever and contact aspiration versus stent retriever alone for acute large vessel occlusion: data from ANGEL-ACT registry
MethodsStudy populationFrom November 2017 to March 2019, the Endovascular Treatment Key Technique and Emergency Work Flow ...
Haemorrhage risk of brain arteriovenous malformation during pregnancy and puerperium
Haemorrhage risk of brain arteriovenous malformation during pregnancy and puerperium
IntroductionBrain arteriovenous malformation (bAVM) is a relatively rare disease with an estimated incidence of approximat...
Homocysteine impedes neurite outgrowth recovery after intracerebral haemorrhage by downregulating pCAMK2A
Homocysteine impedes neurite outgrowth recovery after intracerebral haemorrhage by downregulating pCAMK2A
IntroductionAffecting 2 million people worldwide each year, intracerebral haemorrhage (ICH) is a serious type of stroke, a...
Roles of light transmission aggregometry and CYP2C19 genotype in predicting ischaemic complications during interventional therapy for intracranial aneurysms
Roles of light transmission aggregometry and CYP2C19 genotype in predicting ischaemic complications during interventional therapy for intracranial aneurysms
IntroductionEndovascular therapy is currently one of the most commonly used methods of treating unruptured intracranial an...
Editorial: minor stroke is not minor
Editorial: minor stroke is not minor
Defining minor stroke can be complicated. A minor stroke can be called a mini or small stroke. It is often defined by the ...
MALAT1 promotes platelet activity and thrombus formation through PI3k/Akt/GSK-3{beta} signalling pathway
MALAT1 promotes platelet activity and thrombus formation through PI3k/Akt/GSK-3{beta} signalling pathway
IntroductionPlatelets are blood cells involved in a wide variety of both healthy and diseased processes. Platelets are vit...
Aetiology of extracranial carotid free-floating thrombus in a prospective multicentre cohort
Aetiology of extracranial carotid free-floating thrombus in a prospective multicentre cohort
WHAT IS ALREADY KNOWN ON THIS TOPICHOW THIS STUDY MIGHT AFFECT RESEARCH, PRACTICE OR POLICYIntroductionCarotid free-floati...
KRAS mutation-induced EndMT of brain arteriovenous malformation is mediated through the TGF-{beta}/BMP-SMAD4 pathway
KRAS mutation-induced EndMT of brain arteriovenous malformation is mediated through the TGF-{beta}/BMP-SMAD4 pathway
IntroductionBrain arteriovenous malformations (bAVMs) constitute a congenital cerebrovascular disease caused by abnormally...
Oestrogen ameliorates blood-brain barrier damage after experimental subarachnoid haemorrhage via the SHH pathway in male rats
Oestrogen ameliorates blood-brain barrier damage after experimental subarachnoid haemorrhage via the SHH pathway in male rats
IntroductionSubarachnoid haemorrhage (SAH), caused mainly by ruptured aneurysms, has remarkably high mortality and disabil...
Prospective, multicentre study of screening, investigation and management of hyponatraemia after subarachnoid haemorrhage in the UK and Ireland
Prospective, multicentre study of screening, investigation and management of hyponatraemia after subarachnoid haemorrhage in the UK and Ireland
WHAT IS ALREADY KNOWN ON THIS TOPICPatients with subarachnoid haemorrhage (SAH) commonly develop hyponatraemia. However, a...
Prevalence and risk factors of stroke in China: a national serial cross-sectional study from 2003 to 2018
Prevalence and risk factors of stroke in China: a national serial cross-sectional study from 2003 to 2018
IntroductionStroke is a leading cause of disability and mortality worldwide and imposes a severe global burden.1 2 The Glo...
Management of extracranial carotid artery stenosis during endovascular treatment for acute ischaemic stroke: results from the MR CLEAN Registry
Management of extracranial carotid artery stenosis during endovascular treatment for acute ischaemic stroke: results from the MR CLEAN Registry
IntroductionIn general, 10–20% of the patients with an acute ischaemic stroke due to a proximal intracranial occlusion of ...
Venous thromboembolism among Medicare acute ischaemic stroke patients with and without COVID-19
Venous thromboembolism among Medicare acute ischaemic stroke patients with and without COVID-19
INTRODUCTIONSeveral studies have suggested that infection with SARS-CoV-2, the virus that causes COVID-19 may predispose p...
Rationale and design of a randomised double-blind 2x2 factorial trial comparing the effect of a 3-month intensive statin and antiplatelet therapy for patients with acute mild ischaemic stroke or high-risk TIA with intracranial or extracranial atherosclerosis (INSPIRES)
Rationale and design of a randomised double-blind 2x2 factorial trial comparing the effect of a 3-month intensive statin and antiplatelet therapy for patients with acute mild ischaemic stroke or high-risk TIA with intracranial or extracranial atherosclerosis (INSPIRES)
IntroductionThe high risk of stroke recurrence within 90 days was reported in patients with acute mild ischaemic stroke or...
Correction: Cilostazol and isosorbide mononitrate for the prevention of progression of : baseline data and statistical analysis plan for the Lacunar Intervention Trial-2 (LACI-2) (ISRCTN14911850)
Correction: Cilostazol and isosorbide mononitrate for the prevention of progression of : baseline data and statistical analysis plan for the Lacunar Intervention Trial-2 (LACI-2) (ISRCTN14911850)
Bath PM, Mhlanga I, Woodhouse LJ, et al. Cilostazol and isosorbide mononitrate for the prevention of progression of : base...
Circulating endothelial microvesicles and their carried miR-125a-5p: potential biomarkers for ischaemic stroke
Circulating endothelial microvesicles and their carried miR-125a-5p: potential biomarkers for ischaemic stroke
IntroductionStroke is a major reason for death and disability worldwide, of which ischaemic stroke (IS) accounts for about...
Somatic mutation contributing to clonal haematopoiesis is a risk factor of recurrent stroke in first-ever acute ischaemic stroke: a prospective cohort study
Somatic mutation contributing to clonal haematopoiesis is a risk factor of recurrent stroke in first-ever acute ischaemic stroke: a prospective cohort study
WHAT IS ALREADY KNOWN ON THIS TOPICClonal haematopoiesis of indeterminate potential (CHIP) describes individuals with soma...
ADVISING score: a reliable grading scale based on injury and response for intracerebral haemorrhage
ADVISING score: a reliable grading scale based on injury and response for intracerebral haemorrhage
IntroductionIntracerebral haemorrhage (ICH) is the second most common stroke subtype and accounts for 15%–30% of stroke ca...
Associations of HDL-C/LDL-C with myocardial infarction, all-cause mortality, haemorrhagic stroke and ischaemic stroke: a longitudinal study based on 384 093 participants from the UK Biobank
Associations of HDL-C/LDL-C with myocardial infarction, all-cause mortality, haemorrhagic stroke and ischaemic stroke: a longitudinal study based on 384 093 participants from the UK Biobank
WHAT IS ALREADY KNOWN ON THIS TOPICThe high-density lipoprotein cholesterol (HDL-C)/low-density lipoprotein cholesterol (L...
Low LDL-C level and intracranial haemorrhage risk after ischaemic stroke: a prospective cohort study
Low LDL-C level and intracranial haemorrhage risk after ischaemic stroke: a prospective cohort study
IntroductionFor secondary prevention, patients who had an ischaemic stroke (IS) have been recommended to receive lipid-low...
Measures of intracranial compartments in acute intracerebral haemorrhage: data from the Rapid Intervention with Glyceryl Trinitrate in Hypertensive Stroke-2 Trial (RIGHT-2)
Measures of intracranial compartments in acute intracerebral haemorrhage: data from the Rapid Intervention with Glyceryl Trinitrate in Hypertensive Stroke-2 Trial (RIGHT-2)
Background and purposeNon-contrast CT scanning is the mainstay for diagnosing intracerebral haemorrhage (ICH) and is cost-...
Deep white matter hyperintensity is spatially correlated to MRI-visible perivascular spaces in cerebral small vessel disease on 7 Tesla MRI
Deep white matter hyperintensity is spatially correlated to MRI-visible perivascular spaces in cerebral small vessel disease on 7 Tesla MRI
IntroductionWhite matter hyperintensity (WMH), which has been frequently observed in older people, is one radiological fea...
Endovascular therapy in acute anterior circulation large vessel occlusive patients with a large infarct core (ANGEL-ASPECT): protocol of a multicentre randomised trial
Endovascular therapy in acute anterior circulation large vessel occlusive patients with a large infarct core (ANGEL-ASPECT): protocol of a multicentre randomised trial
ANGEL-ASPECT study is a multicentred, prospective, randomised, open-label, blinded End-point (PROBE) trial. Patients with ...
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