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Initial antihypertensive agent effects on acute blood pressure after intracerebral haemorrhage
Initial antihypertensive agent effects on acute blood pressure after intracerebral haemorrhage
Key messageWhat is already known on this topicFor patients suffering from acute intracerebral haemorrhage (ICH) with initi...
Functional status at 30 and 90 days after mild ischaemic stroke
Functional status at 30 and 90 days after mild ischaemic stroke
Key messagesWhat is already known on this topicFunctional status at 30 days poststroke has been shown to be a reliable pre...
Long-term modification of gut microbiota by broad-spectrum antibiotics improves stroke outcome in rats
Long-term modification of gut microbiota by broad-spectrum antibiotics improves stroke outcome in rats
IntroductionFaecal microbiota transplantation, treatments with broad-spectrum antibiotics and the provision of probiotics ...
Grading scale based on arcuate fasciculus segmentation to predict postoperative language outcomes of brain arteriovenous malformations
Grading scale based on arcuate fasciculus segmentation to predict postoperative language outcomes of brain arteriovenous malformations
IntroductionWith fibres scattered in the Broca’s, Wernicke’s and Geschwind’s area, the arcuate fasciculus (AF) is consider...
Geometric features of middle cerebral artery are associated with spontaneous basal ganglia intracerebral haemorrhage
Geometric features of middle cerebral artery are associated with spontaneous basal ganglia intracerebral haemorrhage
IntroductionAlthough spontaneous intracerebral haemorrhage (ICH) accounts for less than 20% of cases of stroke, it represe...
Contemporary antiplatelet therapy for secondary stroke prevention: a narrative review of current literature and guidelines
Contemporary antiplatelet therapy for secondary stroke prevention: a narrative review of current literature and guidelines
Single-antiplatelet therapyAspirinAspirin irreversibly inactivates cyclooxygenase 1 (COX1) and inhibits platelet aggregati...
Indobufen versus aspirin in acute ischaemic stroke (INSURE): rationale and design of a multicentre randomised trial
Indobufen versus aspirin in acute ischaemic stroke (INSURE): rationale and design of a multicentre randomised trial
Introduction and rationaleStroke is the second leading cause of death worldwide and the leading cause of mortality and dis...
Retrograde recanalisation for vertebral artery stump syndrome: a case report
Retrograde recanalisation for vertebral artery stump syndrome: a case report
IntroductionCarotid artery stump syndrome is an embolic source for ischaemic stroke.1 Ischaemic stroke following carotid a...
LDL-C levels, lipid-lowering treatment and recurrent stroke in minor ischaemic stroke or TIA
LDL-C levels, lipid-lowering treatment and recurrent stroke in minor ischaemic stroke or TIA
IntroductionDyslipidaemia is a major risk factor for atherosclerotic cardiovascular disease and reduction of low-density l...
Inflammatory biomarkers and cerebral small vessel disease: a community-based cohort study
Inflammatory biomarkers and cerebral small vessel disease: a community-based cohort study
IntroductionCerebral small vessel disease (CSVD) refers to a group of heterogeneous clinical syndromes caused by cerebral ...
Circulating immune cell landscape in patients who had mild ischaemic stroke
Circulating immune cell landscape in patients who had mild ischaemic stroke
IntroductionStroke is the fifth leading cause of death in the USA and remains a serious disability for adults.1 2 Early an...
Characterising acute ischaemic stroke thrombi: insights from histology, imaging and emerging impedance-based technologies
Characterising acute ischaemic stroke thrombi: insights from histology, imaging and emerging impedance-based technologies
Occlusion of a cerebral artery by a thrombus results in acute ischaemic stroke (AIS). Treatment of AIS aims to recanalise ...
White matter hyperintensity progression is associated with incident probable dementia or mild cognitive impairment
White matter hyperintensity progression is associated with incident probable dementia or mild cognitive impairment
Summary boxWhat is already known about this subjectThe burden of white matter hyperintensity (WMH) on brain MRI is associa...
To bridge or not to bridge: summary of the new evidence in endovascular stroke treatment
To bridge or not to bridge: summary of the new evidence in endovascular stroke treatment
What is already knownRecently published summaries and meta-analyses of four randomised controlled trials (RCTs)1–5 compari...
Genome sequencing reveals the role of rare genomic variants in Chinese patients with symptomatic intracranial atherosclerotic disease
Genome sequencing reveals the role of rare genomic variants in Chinese patients with symptomatic intracranial atherosclerotic disease
IntroductionAs a global major ischaemic stroke subtype, intracranial atherosclerotic disease (ICAD) constitutes 33%–50% of...
Endovascular treatment with or without intravenous alteplase for acute ischaemic stroke due to basilar artery occlusion
Endovascular treatment with or without intravenous alteplase for acute ischaemic stroke due to basilar artery occlusion
IntroductionBasilar artery occlusion (BAO) accounts for about 2% of all stroke cases and has a high mortality rate and ris...
Effect of haemodynamics on the risk of ischaemic stroke in patients with severe vertebral artery stenosis
Effect of haemodynamics on the risk of ischaemic stroke in patients with severe vertebral artery stenosis
IntroductionApproximately one-fifth of all ischaemic strokes occur in the posterior circulation system, and steno-occlusiv...
Mobile stroke care expedites intravenous thrombolysis and endovascular thrombectomy
Mobile stroke care expedites intravenous thrombolysis and endovascular thrombectomy
IntroductionFassbender et al introduced the concept of a mobile stroke unit (MSU) in 2003, the essential components of whi...
Dl-3-n-butylphthalide attenuates brain injury caused by cortical infarction accompanied by cranial venous drainage disturbance
Dl-3-n-butylphthalide attenuates brain injury caused by cortical infarction accompanied by cranial venous drainage disturbance
IntroductionGood collateral has always been considered a predictor of small ischaemic core lesions and a key factor for th...
Discrepancies between clinical and autopsy findings in patients who had an acute stroke
Discrepancies between clinical and autopsy findings in patients who had an acute stroke
IntroductionThe autopsy is the ultimate medical tool used not only to confirm the diagnosis and the appropriateness of the...
Clinical and radiological features of medullary infarction caused by spontaneous vertebral artery dissection
Clinical and radiological features of medullary infarction caused by spontaneous vertebral artery dissection
IntroductionsMedullary infarction (MI) is a rare but important type of ischaemic stroke. Increasing attention has been pai...