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Near-infrared upconversion multimodal nanoparticles for targeted radionuclide therapy of breast cancer lymphatic metastases
Near-infrared upconversion multimodal nanoparticles for targeted radionuclide therapy of breast cancer lymphatic metastases
The theranostics of lymph node metastasis has always been one of the major obstacles to defeating breast cancer and an imp...
The Yin-Yang of myeloid cells in the leukemic microenvironment: Immunological role and clinical implications
The Yin-Yang of myeloid cells in the leukemic microenvironment: Immunological role and clinical implications
The leukemic microenvironment has a high diversity of immune cells that are phenotypically and functionally distinct. Howe...
Integrated bioinformatics to identify potential key biomarkers for COVID-19-related chronic urticaria
Integrated bioinformatics to identify potential key biomarkers for COVID-19-related chronic urticaria
BackgroundA lot of studies have revealed that chronic urticaria (CU) is closely linked with COVID-19. However, there is a ...
Multiple sclerosis-disease modifying therapies affect humoral and T-cell response to mRNA COVID-19 vaccine
Multiple sclerosis-disease modifying therapies affect humoral and T-cell response to mRNA COVID-19 vaccine
BackgroundThe mRNA vaccines help protect from COVID-19 severity, however multiple sclerosis (MS) disease modifying therapi...
Resolvin D2 induces anti-microbial mechanisms in a model of infectious peritonitis and secondary lung infection
Resolvin D2 induces anti-microbial mechanisms in a model of infectious peritonitis and secondary lung infection
In severe bacterial infections, there is a pro-inflammatory response to promote bacterial clearance but this response can ...
Rapid response in relapsed follicular lymphoma with massive chylous ascites to anti-CD19 CAR T therapy using Piggy Bac: A case report
Rapid response in relapsed follicular lymphoma with massive chylous ascites to anti-CD19 CAR T therapy using Piggy Bac: A case report
CD19-directed chimeric antigen receptor (CAR) T cell therapy has been shown to achieve a considerably durable response in ...
Ensemble deep learning enhanced with self-attention for predicting immunotherapeutic responses to cancers
Ensemble deep learning enhanced with self-attention for predicting immunotherapeutic responses to cancers
IntroductionDespite the many benefits immunotherapy has brought to patients with different cancers, its clinical applicati...
The CARDS toxin of Mycoplasma pneumoniae induces a positive feedback loop of type 1 immune response
The CARDS toxin of Mycoplasma pneumoniae induces a positive feedback loop of type 1 immune response
BackgroundWithin the past 3-5 years, Mycoplasma pneumoniae has become a major pathogen of community-acquired pneumonia in ...
Case report: Transfusion independence and abolition of extravascular hemolysis in a PNH patient treated with pegcetacoplan
Case report: Transfusion independence and abolition of extravascular hemolysis in a PNH patient treated with pegcetacoplan
More than half of patients with paroxysmal nocturnal hemoglobinuria (PNH) treated with complement fraction C5 inhibitors e...
Interferon and interferon-stimulated genes in HBV treatment
Interferon and interferon-stimulated genes in HBV treatment
Human hepatitis B virus (HBV) is a small enveloped DNA virus with a complex life cycle. It is the causative agent of acute...
Phosphorylation of RIPK1 serine 25 mediates IKK dependent control of extrinsic cell death in T cells
Phosphorylation of RIPK1 serine 25 mediates IKK dependent control of extrinsic cell death in T cells
The Inhibitor of Kappa B Kinase (IKK) complex is a critical regulator of NF-κB activation. More recently, IKK has also bee...
SARS-CoV-2 infection of phagocytic immune cells and COVID-19 pathology: Antibody-dependent as well as independent cell entry
SARS-CoV-2 infection of phagocytic immune cells and COVID-19 pathology: Antibody-dependent as well as independent cell entry
Our review summarizes the evidence that COVID-19 can be complicated by SARS-CoV-2 infection of immune cells. This evidence...
ATG-Fresenius increases the risk of red blood cell transfusion after kidney transplantation
ATG-Fresenius increases the risk of red blood cell transfusion after kidney transplantation
IntroductionIn sensitized deceased donor kidney allograft recipients, the most frequent induction therapy is anti-thymocyt...
Risk of psoriasis in people with hidradenitis suppurativa: A systematic review and meta-analysis
Risk of psoriasis in people with hidradenitis suppurativa: A systematic review and meta-analysis
BackgroundHidradenitis suppurativa were associated with comorbidities in various organ systems. Inflammatory dermatologica...
CMV reactivation initiates long-term expansion and differentiation of the NK cell repertoire
CMV reactivation initiates long-term expansion and differentiation of the NK cell repertoire
IntroductionNK cells play an important role in suppression of viral replication and are critical for effective control of ...
Decreased absolute number of peripheral regulatory T cells in patients with idiopathic retroperitoneal fibrosis
Decreased absolute number of peripheral regulatory T cells in patients with idiopathic retroperitoneal fibrosis
ObjectiveIn order to determine whether the immune balance of T helper 17(Th17)/regulatory T(Treg) is related to the pathog...
Analyzing the immunogenicity of bivalent booster vaccinations in healthcare workers: The SWITCH ON trial protocol
Analyzing the immunogenicity of bivalent booster vaccinations in healthcare workers: The SWITCH ON trial protocol
Vaccination against coronavirus disease 2019 (COVID-19) has contributed greatly to providing protection against severe dis...
Immune landscape and immunotherapy for penile cancer
Immune landscape and immunotherapy for penile cancer
Penile cancer is a rare malignancy and usually refers to penile squamous cell carcinoma (PSCC), which accounts for more th...
Single-cell RNA-sequencing in asthma research
Single-cell RNA-sequencing in asthma research
Asthma is a complex and heterogeneous disease with multicellular involvement, and knowledge gaps remain in our understandi...
Vesicle-mediated transport-related genes are prognostic predictors and are associated with tumor immunity in lung adenocarcinoma
Vesicle-mediated transport-related genes are prognostic predictors and are associated with tumor immunity in lung adenocarcinoma
BackgroundGlobally, lung adenocarcinoma (LUAD) is the leading cause of cancer-related deaths. It is a progressive disorder...
The prognostic value of the systemic immune-inflammation index for patients with bladder cancer after radical cystectomy
The prognostic value of the systemic immune-inflammation index for patients with bladder cancer after radical cystectomy
BackgroundBiomarkers acquired from blood samples are easy to obtain and cost-effective, have attracted considerable intere...
Development of a copper metabolism-related gene signature in lung adenocarcinoma
Development of a copper metabolism-related gene signature in lung adenocarcinoma
PurposeThe dysregulation of copper metabolism is closely related to the occurrence and progression of cancer. This study a...