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Editorial: Therapeutic neuromodulation for aging-related disorders associated with the autonomic nervous system
Editorial: Therapeutic neuromodulation for aging-related disorders associated with the autonomic nervous system
For over 25 years, scientists have shown a number of mechanisms associated with central activity (neuronal pathways and ci...
Two-sample Mendelian randomization analysis of 91 circulating inflammatory protein levels and amyotrophic lateral sclerosis
Two-sample Mendelian randomization analysis of 91 circulating inflammatory protein levels and amyotrophic lateral sclerosis
IntroductionAmyotrophic Lateral Sclerosis (ALS) is a neurodegenerative disease with poorly understood pathophysiology. Rec...
Frequency-dependent alterations in functional connectivity in patients with Alzheimer’s Disease spectrum disorders
Frequency-dependent alterations in functional connectivity in patients with Alzheimer’s Disease spectrum disorders
BackgroundIn the spectrum of Alzheimer’s Disease (AD) and related disorders, the resting-state functional magnetic resonan...
The assessment of executive function abilities in healthy and neurodegenerative aging—A selective literature review
The assessment of executive function abilities in healthy and neurodegenerative aging—A selective literature review
Numerous studies have examined executive function (EF) abilities in cognitively healthy older adults and those living with...
Causal role of immune cells on risk of Parkinson’s disease: a Mendelian randomization study
Causal role of immune cells on risk of Parkinson’s disease: a Mendelian randomization study
BackgroundPrevious observational studies have suggested a correlation between immune cells and Parkinson’s disease (PD), y...
Bibliometric analysis of PTEN in neurodevelopment and neurodegeneration
Bibliometric analysis of PTEN in neurodevelopment and neurodegeneration
Phosphatase and tensin homologue deleted on chromosome ten (PTEN) was initially recognized as a significant regulator of c...
Repetitive transcranial magnetic stimulation for Alzheimer’s disease: an overview of systematic reviews and meta-analysis
Repetitive transcranial magnetic stimulation for Alzheimer’s disease: an overview of systematic reviews and meta-analysis
ObjectiveAlzheimer’s disease (AD) is a prevalent neurodegenerative condition that significantly impacts both individuals a...
Association between cognitive function and body composition in older adults: data from NHANES (1999–2002)
Association between cognitive function and body composition in older adults: data from NHANES (1999–2002)
AimTo investigate the association between cognitive function and body composition in older adults.MethodsWe collected data...
Reduced maximal range of ocular movements and its response to acute levodopa challenge in Parkinson's disease
Reduced maximal range of ocular movements and its response to acute levodopa challenge in Parkinson's disease
IntroductionAlthough restriction of vertical ocular range of motion is known to be the hallmark of progressive supranuclea...
Light on Alzheimer's disease: from basic insights to preclinical studies
Light on Alzheimer's disease: from basic insights to preclinical studies
Alzheimer’s Disease (AD), referring to a gradual deterioration in cognitive function, including memory loss and impaired t...
Association between dietary inflammatory index and cognitive impairment among American elderly: a cross-sectional study
Association between dietary inflammatory index and cognitive impairment among American elderly: a cross-sectional study
BackgroundIt has been shown that inflammation may be associated with cognitive impairment (CI). Diet modulates inflammatio...
MRI brain structural and functional networks changes in Parkinson disease with REM sleep behavior disorders
MRI brain structural and functional networks changes in Parkinson disease with REM sleep behavior disorders
BackgroundRapid eye movement sleep behavior disorder (RBD) is common in individuals with Parkinson’s disease (PD). In spit...
Age-related increase in the expression of 11β-hydroxysteroid dehydrogenase type 1 in the hippocampus of male rhesus macaques
Age-related increase in the expression of 11β-hydroxysteroid dehydrogenase type 1 in the hippocampus of male rhesus macaques
IntroductionThe hippocampus is especially susceptible to age-associated neuronal pathologies, and there is concern that th...
Executive and memory dysfunction related to binge drinking in stroke survivors during a 9-year follow-up
Executive and memory dysfunction related to binge drinking in stroke survivors during a 9-year follow-up
BackgroundIschemic stroke and heavy alcohol consumption are both known risk factors for cognitive impairment. The issue ga...
Automatic assessment of disproportionately enlarged subarachnoid-space hydrocephalus from 3D MRI using two deep learning models
Automatic assessment of disproportionately enlarged subarachnoid-space hydrocephalus from 3D MRI using two deep learning models
BackgroundDisproportionately enlarged subarachnoid-space hydrocephalus (DESH) is a key feature for Hakim disease (idiopath...
Aging effects on the encoding/retrieval flip in associative memory: fMRI evidence from incidental contingency learning
Aging effects on the encoding/retrieval flip in associative memory: fMRI evidence from incidental contingency learning
IntroductionAssociative memory is arguably the most basic memory function and therein constitutes the foundation of all ep...
Analyzing changes in parkinsonian speech over time: a diachronic experimental phonetics study
Analyzing changes in parkinsonian speech over time: a diachronic experimental phonetics study
In this contribution the use of web resources for the longitudinal study of speech rhythm of a ‘well-known’ person diagnos...
Editorial: Bioinformatics analysis of single cell sequencing and multi-omics in the aging and age-associated diseases
Editorial: Bioinformatics analysis of single cell sequencing and multi-omics in the aging and age-associated diseases
molecular diversity within cells, shedding light on cell type-specific aging markers crucial for understanding brain aging...
Physical exercise frequency and cognition: a multicenter cross-sectional cohort study
Physical exercise frequency and cognition: a multicenter cross-sectional cohort study
Background and aimsDementia imposes a heavy burden on society and families, therefore, effective drug treatments, explorin...
Exploring the application and challenges of fNIRS technology in early detection of Parkinson’s disease
Exploring the application and challenges of fNIRS technology in early detection of Parkinson’s disease
BackgroundParkinson’s disease (PD) is a prevalent neurodegenerative disorder that significantly benefits from early diagno...
Regional covariance of white matter hyperintensity volume patterns associated with hippocampal volume in healthy aging
Regional covariance of white matter hyperintensity volume patterns associated with hippocampal volume in healthy aging
Hippocampal volume is particularly sensitive to the accumulation of total brain white matter hyperintensity volume (WMH) i...