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Author Correction: Sequential immunotherapy: towards cures for autoimmunity
In the version of the article initially published, the following text was missing from the Acknowledgements, and has now b...
Antibody sniffs out tau
Discover the world’s best science and medicine | Nature.com
Molecular glue degrader for sickle cell disease
Discover the world’s best science and medicine | Nature.com
Rebalancing calcium in Alzheimer disease
Rebalancing calcium in Alzheimer disease
Discover the world’s best science and medicine | Nature.com
Targeting ROS in cancer: rationale and strategies
Targeting ROS in cancer: rationale and strategies
Reactive oxygen species (ROS) in biological systems are transient but essential molecules that are generated and eliminate...
A rush of CRISPR to the lungs
A rush of CRISPR to the lungs
Discover the world’s best science and medicine | Nature.com
Data science in pharmaceutical R&D: the DISRUPT-DS industry roundtable
The DISRUPT-DS roundtable, which brings together data science leaders from large pharmaceutical companies, aims to be a fo...
FDA new drug approvals in Q2 2024
Discover the world’s best science and medicine | Nature.com
Chromatin remodellers as therapeutic targets
Chromatin remodellers as therapeutic targets
Large-scale cancer genome sequencing studies have revealed that chromatin regulators are frequently mutated in cancer. In ...
Eli Lilly spends $3.2 billion on Morphic’s oral integrin inhibitor for inflammatory bowel disease
Discover the world’s best science and medicine | Nature.com
Show them the money: a multi-stakeholder perspective on reforming clinical trial participant compensation
Clinical trial participant compensation is badly overdue for thoughtful reform. The first step: generating consensus acros...
Machine learning identifies AMPs
Discover the world’s best science and medicine | Nature.com
Discovering CFTR modulators
Discover the world’s best science and medicine | Nature.com
ETS2 drives IBD
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A selective microbiome-sparing antibiotic
Discover the world’s best science and medicine | Nature.com
When chronic and rare disease worlds converge
When chronic and rare disease worlds converge
Sharon Barr, head of BioPharmaceuticals R&D at AstraZeneca, discusses her chronic disease research priorities, includi...
Gene therapies start the climb from rare disease base camps to common disease peaks
Gene therapies start the climb from rare disease base camps to common disease peaks
Jude Samulski, former CSO and co-founder of AskBio, discusses the future of gene therapy for complex and common diseases, ...
Extracellular targeted protein degrader removes antibodies in first test in humans
Extracellular targeted protein degrader removes antibodies in first test in humans
Biohaven’s BHV-1300 lowered levels of immunoglobulin G in the blood of healthy volunteers — a first clinical demonstration...
FDA approves 21-valent pneumococcal vaccine
Discover the world’s best science and medicine | Nature.com
Menin inhibitors seek to debut as newest targeted therapy for leukaemia
Menin inhibitors seek to debut as newest targeted therapy for leukaemia
Small molecules that block a key protein–protein interaction could change the treatment landscape for many patients with a...
Author Correction: The state of the art in secondary pharmacology and its impact on the safety of new medicines
Stephen JenkinsonPresent address: Metrion Biosciences, San Diego, CA, USAMalar PannirselvamPresent address: GSK, Waltham, ...
Know your molecule: pharmacological characterization of drug candidates to enhance efficacy and reduce late-stage attrition
Know your molecule: pharmacological characterization of drug candidates to enhance efficacy and reduce late-stage attrition
Despite advances in chemical, computational and biological sciences, the rate of attrition of drug candidates in clinical ...
Upcoming market catalysts in Q3 2024
Upcoming market catalysts in Q3 2024
Discover the world’s best science and medicine | Nature.com
FDA approves first telomerase inhibitor
FDA approves first telomerase inhibitor
Discover the world’s best science and medicine | Nature.com
Chromatin-targeted drug discovery at “a very special moment”
Chromatin-targeted drug discovery at “a very special moment”
Cigall Kadoch, a cancer researcher at Dana-Farber Cancer Institute and co-founder of Foghorn Therapeutics, discusses the c...
Antisense and CRISPR-based drugs build cases for better hereditary angioedema treatments
Discover the world’s best science and medicine | Nature.com
RNA delivery heats up cold tumours
RNA delivery heats up cold tumours
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Expanding the psychedelic toolkit
Expanding the psychedelic toolkit
Discover the world’s best science and medicine | Nature.com
A route to small-molecule Lp(a) inhibitors for heart disease
A route to small-molecule Lp(a) inhibitors for heart disease
Discover the world’s best science and medicine | Nature.com
FDA approves mRNA-based RSV vaccine
Discover the world’s best science and medicine | Nature.com
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