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RNA-editing drugs advance into clinical trials
RNA-editing drugs advance into clinical trials
ADAR-based editors that can change the mRNA code offer new opportunities in both rare genetic diseases and common complex ...
Targeting immunogenic cell stress and death for cancer therapy
Targeting immunogenic cell stress and death for cancer therapy
Immunogenic cell death (ICD), which results from insufficient cellular adaptation to specific stressors, occupies a centra...
The antibody–drug conjugate landscape
The antibody–drug conjugate landscape
Discover the world’s best science and medicine | Nature.com
Three-step cures for autoimmune diseases?
Three-step cures for autoimmune diseases?
Robert Plenge, head of Research at Bristol Myers Squibb, discusses his vision of sequential immunotherapy for autoimmune d...
FDA new drug approvals in Q1 2024
Discover the world’s best science and medicine | Nature.com
FDA approves first complement factor D inhibitor
Discover the world’s best science and medicine | Nature.com
Small molecule improves muscle function in myasthenia gravis
Small molecule improves muscle function in myasthenia gravis
Discover the world’s best science and medicine | Nature.com
FDA approves an HDAC inhibitor for Duchenne muscular dystrophy
Discover the world’s best science and medicine | Nature.com
Non-antibiotic drug network reveals new leads for antibiotics
Non-antibiotic drug network reveals new leads for antibiotics
Discover the world’s best science and medicine | Nature.com
PROTAC induces HIV-1 Nef degradation
Discover the world’s best science and medicine | Nature.com
Sterol analogue suppresses hedgehog signalling
Discover the world’s best science and medicine | Nature.com
Antibody drug conjugate combats inflammation
Discover the world’s best science and medicine | Nature.com
Restoring a youthful immune system
Discover the world’s best science and medicine | Nature.com
The landscape of small-molecule prodrugs
The landscape of small-molecule prodrugs
Prodrugs are derivatives with superior properties compared with the parent active pharmaceutical ingredient (API), which u...
Novel drug targets in 2023
Discover the world’s best science and medicine | Nature.com
RNAi-based drug design: considerations and future directions
RNAi-based drug design: considerations and future directions
More than 25 years after its discovery, the post-transcriptional gene regulation mechanism termed RNAi is now transforming...
FDA approves gene therapy for metachromatic leukodystrophy, the tenth for a genetic disease and the priciest yet
Discover the world’s best science and medicine | Nature.com
FDA approves Merck & Co’s pulmonary arterial hypertension drug sotatercept
Discover the world’s best science and medicine | Nature.com
Kinase inhibitor rescues the liver
Kinase inhibitor rescues the liver
Discover the world’s best science and medicine | Nature.com
AI serves up target and inhibitor for lung fibrosis
AI serves up target and inhibitor for lung fibrosis
Discover the world’s best science and medicine | Nature.com
Engineered T cells call for back-up
Engineered T cells call for back-up
Discover the world’s best science and medicine | Nature.com
NASH field celebrates ‘hurrah moment’ with a first FDA drug approval for the liver disease
NASH field celebrates ‘hurrah moment’ with a first FDA drug approval for the liver disease
Madrigal’s resmetirom has scored a landmark FDA win, bolstering hopes for a diverse pipeline of drugs for non-alcoholic st...
Genome-editing medicinal products: the EMA perspective
Genome-editing medicinal products: the EMA perspective
Discover the world’s best science and medicine | Nature.com
Upcoming market catalysts in Q2 2024
Discover the world’s best science and medicine | Nature.com
Shifts in the clinical trial landscape
Discover the world’s best science and medicine | Nature.com
GSK’s first-in-class antibiotic secures another phase III win, approaches regulatory run
Discover the world’s best science and medicine | Nature.com
The European Innovation Network as a hub for medicines innovation in Europe
The European Innovation Network is working to support the European medical innovation ecosystem by facilitating early dial...
Top companies and drugs by sales in 2023
Top companies and drugs by sales in 2023
Discover the world’s best science and medicine | Nature.com
Making macrophages with anti-tumour activity
Discover the world’s best science and medicine | Nature.com
Increasing the potency of T cell therapies
Discover the world’s best science and medicine | Nature.com
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