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FDA approves first Friedreich’s ataxia drug
Discover the world’s best science and medicine | Nature.com
Lighting up the biological darkness, with structures and chemical probes
Lighting up the biological darkness, with structures and chemical probes
Aled Edwards celebrates 20 years of open science at the Structural Genomics Consortium — and keeps calling for more focus ...
Ribosome inhibitor combats bacterial drug resistance
Ribosome inhibitor combats bacterial drug resistance
Discover the world’s best science and medicine | Nature.com
Testing the genome-editing toolkit in cardiomyopathy
Testing the genome-editing toolkit in cardiomyopathy
Discover the world’s best science and medicine | Nature.com
Organoids illuminate NAFLD pathogenesis
Organoids illuminate NAFLD pathogenesis
Discover the world’s best science and medicine | Nature.com
Proximity-inducing drugs get closer
Proximity-inducing drugs get closer
Move over degraders; proximity-inducing drugs that stabilize, phosphorylate and inhibit their targets are coming through.
R&D re-balancing act
R&D re-balancing act
Discover the world’s best science and medicine | Nature.com
Hopes scuppered for two more lupus drugs
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Inhibiting cap snatching
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Expanding HSCs without cytokines
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Understanding psychedelic antidepressant action
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Upcoming market catalysts in Q2 2023
Upcoming market catalysts in Q2 2023
Discover the world’s best science and medicine | Nature.com
The opportunity for greater patient and public involvement and engagement in drug development and regulation
Patients and the wider public are beneficiaries of scientific research that leads to new drugs and medical technologies, b...
PIKfyve inhibition rescues ALS pathology
PIKfyve inhibition rescues ALS pathology
Discover the world’s best science and medicine | Nature.com
Delivering on the promise of protein degraders
Delivering on the promise of protein degraders
Over the past 3 years, the first bivalent protein degraders intentionally designed for targeted protein degradation ...
Trends in the global antibiotics market
Trends in the global antibiotics market
Discover the world’s best science and medicine | Nature.com
Application of Bayesian approaches in drug development: starting a virtuous cycle
Application of Bayesian approaches in drug development: starting a virtuous cycle
The pharmaceutical industry and its global regulators have routinely used frequentist statistical methods, such as null hy...
Mini-organs attract big pharma
Mini-organs attract big pharma
Hans Clevers, head of Pharma Research & Early Development at Roche, discusses the role for organoids in drug discovery...
The evolving role of investigative toxicology in the pharmaceutical industry
The evolving role of investigative toxicology in the pharmaceutical industry
For decades, preclinical toxicology was essentially a descriptive discipline in which treatment-related effects were caref...
Drug sales to reach $1.9 trillion within 5 years?
Drug sales to reach $1.9 trillion within 5 years?
Discover the world’s best science and medicine | Nature.com
New dose optimization guidance released for cancer drugs
Discover the world’s best science and medicine | Nature.com
FDA approves first hypoxia-inducible factor prolyl hydroxylase inhibitor
FDA approves first hypoxia-inducible factor prolyl hydroxylase inhibitor
Discover the world’s best science and medicine | Nature.com
Targeting galectin-driven regulatory circuits in cancer and fibrosis
Targeting galectin-driven regulatory circuits in cancer and fibrosis
Galectins are a family of endogenous glycan-binding proteins that have crucial roles in a broad range of physiological and...
Drugging a metabolic vulnerability in glioblastoma
Drugging a metabolic vulnerability in glioblastoma
Discover the world’s best science and medicine | Nature.com
Suppressing c-Abl in Parkinson disease
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Solving opioid receptor structures
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Profiling AAV tropism
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Understanding immunomodulatory antibody agonism
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Strategic recommendations from the STARS project to foster academic drug development
Improved understanding of regulatory requirements by academic researchers can accelerate the translation of new medical in...
Proteomics reveals small molecules’ secrets
Proteomics reveals small molecules’ secrets
Discover the world’s best science and medicine | Nature.com
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