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Drug delivery systems for CRISPR-based genome editors
Drug delivery systems for CRISPR-based genome editors
CRISPR-based drugs can theoretically manipulate any genetic target. In practice, however, these drugs must enter the desir...
Pushing both sides of the drug pricing aisle
Pushing both sides of the drug pricing aisle
ICER’s incoming President, Sarah Emond, discusses drug pricing, multimillion dollar gene therapies and innovation incentives.
Artificial intelligence for natural product drug discovery
Artificial intelligence for natural product drug discovery
Developments in computational omics technologies have provided new means to access the hidden diversity of natural product...
Macrocycle drugs serve up new opportunities
Macrocycle drugs serve up new opportunities
Merck & Co.’s PCSK9 inhibitor MK-0616 showcases the potential of macrocycles as oral drugs for extracellular targets, ...
The next-generation CAR-T therapy landscape
The next-generation CAR-T therapy landscape
Discover the world’s best science and medicine | Nature.com
Upcoming market catalysts in Q4 2023
Upcoming market catalysts in Q4 2023
Discover the world’s best science and medicine | Nature.com
Defining rare conditions in the era of personalized medicine
The total number of rare conditions is debated, partly because of the variety of definitions of what constitutes rare. A b...
Obesity drug scores landmark cardiovascular win
Discover the world’s best science and medicine | Nature.com
A step closer to in vivo editing of haematopoietic stem cells
A step closer to in vivo editing of haematopoietic stem cells
Discover the world’s best science and medicine | Nature.com
FDA approves second RNA aptamer
Discover the world’s best science and medicine | Nature.com
FDA approves first GPRC5D × CD3-targeted bispecific for multiple myeloma
Discover the world’s best science and medicine | Nature.com
Microbiome screening platform finds drugs for bugs
Microbiome screening platform finds drugs for bugs
Discover the world’s best science and medicine | Nature.com
Understanding class B GPCR agonist binding
Discover the world’s best science and medicine | Nature.com
LpxC inhibitor eliminates bacterial infections
Discover the world’s best science and medicine | Nature.com
Lipid metabolite triggers neural repair
Discover the world’s best science and medicine | Nature.com
Author Correction: Bridging the gap between innovation and later-stage financing for biotech in Europe
Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obta...
Antimalarial drug discovery: progress and approaches
Antimalarial drug discovery: progress and approaches
Recent antimalarial drug discovery has been a race to produce new medicines that overcome emerging drug resistance, whilst...
AAV-based in vivo gene therapy for neurological disorders
AAV-based in vivo gene therapy for neurological disorders
Recent advancements in gene supplementation therapy are expanding the options for the treatment of neurological disorders....
Therapeutic approaches for Duchenne muscular dystrophy
Therapeutic approaches for Duchenne muscular dystrophy
Duchenne muscular dystrophy (DMD) is a monogenic muscle-wasting disorder and a priority candidate for molecular and cellul...
Clipping cell-surface mucins in cancer by targeted degradation
Clipping cell-surface mucins in cancer by targeted degradation
Discover the world’s best science and medicine | Nature.com
The company landscape for artificial intelligence in large-molecule drug discovery
The company landscape for artificial intelligence in large-molecule drug discovery
Discover the world’s best science and medicine | Nature.com
A novel approach to boost drug development in paediatric oncology
Despite major advances in cancer research, we are falling short in bringing innovative medicines to children with cancer. ...
Author Correction: Disease modification in inflammatory skin disorders: opportunities and challenges
Authors and AffiliationsDepartment of Dermatology and Allergy, University Hospital, Bonn, GermanyThomas BieberChristine Kü...
Targeting EMT in cancer through netrin-1
Targeting EMT in cancer through netrin-1
Discover the world’s best science and medicine | Nature.com
Chemoproteomic trailblazer advances covalent candidate into the clinic, pushes allosteric agenda
Chemoproteomic trailblazer advances covalent candidate into the clinic, pushes allosteric agenda
Vividion CEO Aleksandra Rizo discusses emerging lessons from the firm’s use of fragment-based screening — including the po...
FDA approves first oral drug for postpartum depression, but rejects it for major depressive disorder
Discover the world’s best science and medicine | Nature.com
Trustworthy AI for safe medicines
Grading requirements according to risk levelWe concur with Hines et al.1 that regulatory requirements should reflect the r...
The therapeutic potential of targeting regulated non-apoptotic cell death
The therapeutic potential of targeting regulated non-apoptotic cell death
Cell death is critical for the development and homeostasis of almost all multicellular organisms. Moreover, its dysregulat...
The high, and redundant, cost of failure in cancer drug development
Discover the world’s best science and medicine | Nature.com
FDA approves long-acting RSV antibody
Discover the world’s best science and medicine | Nature.com
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