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From Genetic Findings to new Intestinal Molecular Targets in Lipid Metabolism
From Genetic Findings to new Intestinal Molecular Targets in Lipid Metabolism
While lipid-lowering therapies demonstrate efficacy, many patients still contend with significant residual risk of atheros...
Angiotensin type 1 and type 2 receptors-induced mitochondrial dysfunction promotes ferroptosis in cardiomyocytes
Angiotensin type 1 and type 2 receptors-induced mitochondrial dysfunction promotes ferroptosis in cardiomyocytes
Previous studies suggest that ferroptosis is involved in cardiovascular diseases. The aim of the present study is to inves...
Intraindividual correlations between nocturnal urination frequency and sleep blood pressure: the Nagahama Study
Intraindividual correlations between nocturnal urination frequency and sleep blood pressure: the Nagahama Study
Nocturnal urination frequency is associated with sleep blood pressure (BP). However, it was uncertain to what extent the s...
Debate: Lipid-lowering Therapies and Diabetes Development
Debate: Lipid-lowering Therapies and Diabetes Development
This review explores the relationship between lipid-lowering therapies, particularly statins, and the risk of new-onset di...
Influence of Persistently Elevated LDL Values on Carotid Intima Media Thickness in Elite Athletes
Influence of Persistently Elevated LDL Values on Carotid Intima Media Thickness in Elite Athletes
Carotid IMT is a recognized marker for early atherosclerotic changes and a predictor of future CV events. Previous studies...
Highlights of the 2024 Chinese hypertension guidelines
Highlights of the 2024 Chinese hypertension guidelines
The 2024 Chinese hypertension guidelines has been recently issued by Chinese Hypertension League (CHL), joint with partner...
Association between equivalized annual household income and regular medical visits for hypertensive patients since the COVID-19 outbreak
Association between equivalized annual household income and regular medical visits for hypertensive patients since the COVID-19 outbreak
Previous studies have shown an increase in blood pressure during the coronavirus disease 2019 (COVID-19) pandemic even amo...
The association of serum total bile acids and deep venous thrombosis
The association of serum total bile acids and deep venous thrombosis
Bile acid metabolism plays a crucial role in maintaining the delicate balance between coagulation and anticoagulation proc...
Ref-1 is overexpressed in neovascular eye disease and targetable with a novel inhibitor
Ref-1 is overexpressed in neovascular eye disease and targetable with a novel inhibitor
Reduction–oxidation factor-1 or apurinic/apyrimidinic endonuclease 1 (Ref-1/APE1) is a crucial redox-sensitive activ...
A novel quantitative angiogenesis assay based on visualized vascular organoid
A novel quantitative angiogenesis assay based on visualized vascular organoid
Angiogenesis describes the sprouting of blood vessels from existing vasculatures and it plays a pivotal role in disease pr...
Statin therapy in primary and secondary cardiovascular disease prevention
Statin therapy in primary and secondary cardiovascular disease prevention
Atherosclerotic cardiovascular disease (ASCVD) is one of the most common causes of death globally and the leading one in t...
Possible antihypertensive effects of mineralocorticoid receptor antagonists other than reducing extracellular water
Possible antihypertensive effects of mineralocorticoid receptor antagonists other than reducing extracellular water
Ohno Y, Sone M, Inagaki N, Yamasaki T, Ogawa O, Takeda Y, et al. Prevalence of Cardiovascular Disease and Its Risk Factors...
Prognostic value of beat-to-beat blood pressure variability parameters in patients after mechanical thrombectomy
Prognostic value of beat-to-beat blood pressure variability parameters in patients after mechanical thrombectomy
The relationship of beat-to-beat blood pressure variability (BPV) with prognosis after mechanical thrombectomy (MT) is unc...
4-Hydroxychalcone attenuates AngII-induced cardiac remodeling and dysfunction via regulating PI3K/AKT pathway
4-Hydroxychalcone attenuates AngII-induced cardiac remodeling and dysfunction via regulating PI3K/AKT pathway
Cardiac remodeling encompasses structural alterations such as hypertrophy, fibrosis, and dilatation, alongside numerous ce...
Effect of oral nintedanib vs placebo on epistaxis in hereditary hemorrhagic telangiectasia: the EPICURE multicenter randomized double-blind trial
Effect of oral nintedanib vs placebo on epistaxis in hereditary hemorrhagic telangiectasia: the EPICURE multicenter randomized double-blind trial
Epistaxis greatly affects patients with hereditary hemorrhagic telangiectasia (HHT). Although few systemic treatment exist...