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Pioneering the Way: The Revolutionary Potential of Antibody–Drug Conjugates in NSCLC
Pioneering the Way: The Revolutionary Potential of Antibody–Drug Conjugates in NSCLC
Despite targeted therapy and immunotherapy being recognized as established frontline treatments for advanced non-small cel...
Ovarian Suppression: Early Menopause and Late Effects
Ovarian Suppression: Early Menopause and Late Effects
Around 90% of breast tumours are diagnosed in the early stage, with approximately 70% being hormone receptor-positive. The...
Evaluation of Homologous Recombination Deficiency in Ovarian Cancer
Homologous recombination deficiency (HRD) is an important biomarker guiding selection of ovarian cancer patients who will ...
Harnessing the Potential of Real-World Evidence in the Treatment of Colorectal Cancer: Where Do We Stand?
Harnessing the Potential of Real-World Evidence in the Treatment of Colorectal Cancer: Where Do We Stand?
Treatment guidelines for colorectal cancer (CRC) are primarily based on the results of randomized clinical trials (RCTs), ...
Who Should Receive Immunotherapy for Advanced Gastroesophageal Cancer?
Who Should Receive Immunotherapy for Advanced Gastroesophageal Cancer?
This paper shines a light on the exciting progress being made in using immunotherapy to treat advanced gastroesophageal ca...
Research Progress on the Use of Metformin in Leukemia Treatment
Research Progress on the Use of Metformin in Leukemia Treatment
Metformin is a first-line drug in the clinical treatment of type 2 diabetes. Its main molecular mechanism involves the act...
Steroid Premedication and Monoclonal Antibody Therapy: Should We Reconsider?
Steroid Premedication and Monoclonal Antibody Therapy: Should We Reconsider?
Monoclonal antibody (mAb) therapy is now considered a main component of cancer therapy in Australia. Although traditionall...
Desmoid Tumors: Current Perspective and Treatment
Desmoid Tumors: Current Perspective and Treatment
Desmoid tumors are rare tumors with a tendency to infiltrate locally. The lack of a standard treatment approach makes choo...
Hypnosis for Symptom Management in Adult Cancer Patients: What is the Evidence?
Hypnosis for Symptom Management in Adult Cancer Patients: What is the Evidence?
As a palliative care specialist and a hypnotherapist, I use therapeutic communication and conversational hypnosis daily in...
Therapeutic Management of Malignant Wounds: An Update
Therapeutic Management of Malignant Wounds: An Update
Malignant fungating wounds (MFW) are severe skin conditions generating tremendous distress in oncological patients with ad...
Surgical Management and Considerations for Patients with Localized High-Risk Prostate Cancer
Surgical Management and Considerations for Patients with Localized High-Risk Prostate Cancer
Localized high-risk (HR) prostate cancer (PCa) is a heterogenous disease state with a wide range of presentations and outc...
Management of Paraneoplastic Syndromes in the Era of Immune Checkpoint Inhibitors
Management of Paraneoplastic Syndromes in the Era of Immune Checkpoint Inhibitors
Our understanding of paraneoplastic neurologic syndromes (PNS) has blossomed over the past few decades. Clinicians have ac...
Strategies to Assess and Manage Frailty among Patients Diagnosed with Primary Malignant Brain Tumors
Strategies to Assess and Manage Frailty among Patients Diagnosed with Primary Malignant Brain Tumors
Frailty refers to a biologic process that results in reduced physiologic and functional reserve. Patients diagnosed with p...
Sentinel Lymph Node Evaluation in Early-Stage Vulvar Cancer
Sentinel Lymph Node Evaluation in Early-Stage Vulvar Cancer
Sentinel lymph node mapping (SLNM) and dissection (SLND) should be used as an alternative to full inguinofemoral lymph nod...
Antibody-Drug Conjugates in Gynecologic Cancers
Antibody-Drug Conjugates in Gynecologic Cancers
Antibody-drug conjugates (ADCs) are a novel class of targeted cancer therapies with the ability to selectively deliver a c...
Current Standards, Multidisciplinary Approaches, and Future Directions in the Management of Extrahepatic Cholangiocarcinoma
Current Standards, Multidisciplinary Approaches, and Future Directions in the Management of Extrahepatic Cholangiocarcinoma
Biliary tract cancers are molecularly and anatomically diverse cancers which include intrahepatic cholangiocarcinoma, extr...
Approach to Patients with High-Risk Localized Prostate Cancer: Radiation Oncology Perspective
Approach to Patients with High-Risk Localized Prostate Cancer: Radiation Oncology Perspective
High-risk localized prostate cancer is a challenging clinical entity to treat, with heterogeneous responses to an evolving...
Systemic Therapy for Melanoma Brain and Leptomeningeal Metastases
Systemic Therapy for Melanoma Brain and Leptomeningeal Metastases
Melanoma has a high propensity to metastasize to the brain which portends a poorer prognosis. With advanced radiation tech...
Research Progress on the Cardiotoxicity of EGFR-TKIs in Non-Small Cell Lung Cancer
Research Progress on the Cardiotoxicity of EGFR-TKIs in Non-Small Cell Lung Cancer
With the development of molecular biology and histology techniques, targeted therapy for non-small cell lung cancer (NSCLC...
Treatment Landscape of Renal Cell Carcinoma
Treatment Landscape of Renal Cell Carcinoma
The treatment landscape of renal cell carcinoma (RCC) has evolved significantly over the past three decades. Active survei...
Liver-Directed Therapy for Neuroendocrine Tumor Metastases in the Era of Peptide Receptor Radionuclide Therapy
Liver-Directed Therapy for Neuroendocrine Tumor Metastases in the Era of Peptide Receptor Radionuclide Therapy
The treatment of neuroendocrine neoplasm (NEN) liver metastases involves a multidisciplinary approach that includes liver-...
Non-Surgical Therapeutic Strategies for Non-Melanoma Skin Cancers
Non-Surgical Therapeutic Strategies for Non-Melanoma Skin Cancers
Non-melanoma skin cancer (NMSC) is a globally prevalent skin disease, with basal cell carcinoma and squamous cell carcinom...
Treatment of Non-Small Cell Lung Cancer with Atypical EGFR Mutations
Treatment of Non-Small Cell Lung Cancer with Atypical EGFR Mutations
EGFR tyrosine kinase inhibitors (TKI) should always be considered when treating advanced/metastatic non-small cell lung ca...
Extent of Resection and Outcomes of Patients with Primary Malignant Brain Tumors
Extent of Resection and Outcomes of Patients with Primary Malignant Brain Tumors
We have level II evidence that attempting a gross total resection of newly diagnosed suspected glioblastoma is preferred w...
Perioperative Immunotherapy in Non-Small Cell Lung Cancer
Perioperative Immunotherapy in Non-Small Cell Lung Cancer
The standard of care in patients with early-stage non-small cell lung cancer (NSCLC) following surgical resection has been...
Precision Medicine in Urothelial Carcinoma: Current Markers to Guide Treatment and Promising Future Directions
Precision Medicine in Urothelial Carcinoma: Current Markers to Guide Treatment and Promising Future Directions
The treatment landscape for urothelial cancer has changed dramatically in the last 10 years, with the approval of several ...