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Myeloproliferative Neoplasms and Cardiovascular Disease: A Review
Myeloproliferative Neoplasms and Cardiovascular Disease: A Review
Myeloproliferative neoplasms (MPN) are a heterogenous group of disorders of clonal hematopoiesis characterized by constitu...
The Trend of the Treatment of Advanced Hepatocellular Carcinoma: Combination of Immunotherapy and Targeted Therapy
The Trend of the Treatment of Advanced Hepatocellular Carcinoma: Combination of Immunotherapy and Targeted Therapy
Hepatocellular carcinoma (HCC) is a common type of tumor worldwide. The development of systemic treatment of advanced HCC ...
Gastrointestinal Cancer Therapy and Cardiotoxicity
Gastrointestinal Cancer Therapy and Cardiotoxicity
Gastrointestinal cancers are a heterogenous group of cancers that share common risk factors with cardiovascular disease. T...
Advancements in Melanoma Therapies: From Surgery to Immunotherapy
Advancements in Melanoma Therapies: From Surgery to Immunotherapy
Melanoma is defined as the most aggressive and deadly form of skin cancer. The treatment of melanoma depends on the&nb...
Management Approaches for High-Risk Cutaneous Squamous Cell Carcinoma with Perineural Invasion: An Updated Review
Management Approaches for High-Risk Cutaneous Squamous Cell Carcinoma with Perineural Invasion: An Updated Review
Cutaneous squamous cell carcinoma (cSCC) stands as the second most prevalent non-melanoma skin cancer worldwide, comprisin...
Small Cell Lung Cancer—An Update on Chemotherapy Resistance
Small Cell Lung Cancer—An Update on Chemotherapy Resistance
Compared to other types of lung cancer, small cell lung cancer (SCLC) exhibits aggressive characteristics that promote dru...
Opportunities and Challenges in Soft Tissue Sarcoma Risk Stratification in the Era of Personalised Medicine
Opportunities and Challenges in Soft Tissue Sarcoma Risk Stratification in the Era of Personalised Medicine
Soft tissue sarcomas (STS) are a rare and heterogeneous group of cancers. Treatment options have changed little in the pas...
Modern Management of Gastric Neuroendocrine Neoplasms
Modern Management of Gastric Neuroendocrine Neoplasms
Gastric neuroendocrine neoplasms (G-NENs) are a heterogeneous group of tumors that broadly fall into two groups. The first...
Cardiovascular Considerations in Patients Undergoing Hematopoietic Cell Transplantation
Cardiovascular Considerations in Patients Undergoing Hematopoietic Cell Transplantation
Cardiac dysfunction is a serious adverse effect of cancer therapies that can interfere with quality of life and impact lon...
Precision Treatment of Anthracycline-Induced Cardiotoxicity: An Updated Review
Precision Treatment of Anthracycline-Induced Cardiotoxicity: An Updated Review
Anthracycline (ANT)-induced cardiotoxicity (AIC) is a particularly prominent form of cancer therapy-related cardiovascular...
Recent Advances in Immunotherapy for Advanced Biliary Tract Cancer
Recent Advances in Immunotherapy for Advanced Biliary Tract Cancer
Biliary tract cancer (BTC) is a heterogeneous group of aggressive malignancies that arise from the epithelium of the bilia...
An Update on the Clinical Status, Challenges, and Future Directions of Oncolytic Virotherapy for Malignant Gliomas
An Update on the Clinical Status, Challenges, and Future Directions of Oncolytic Virotherapy for Malignant Gliomas
Malignant gliomas are common central nervous system tumors that pose a significant clinical challenge due to the lack of e...
External Beam Radiotherapy in the Management of Uveal Melanoma
External Beam Radiotherapy in the Management of Uveal Melanoma
Uveal melanoma is the most common primary ocular tumor in adults. With the evidence demonstrating that episcleral plaque b...
Underlying Mechanisms of Thrombosis Associated with Cancer and Anticancer Therapies
Underlying Mechanisms of Thrombosis Associated with Cancer and Anticancer Therapies
Cancer-associated thrombosis (CAT) has been identified as the second most prevalent cause of death after cancer itself. Mo...
Promising Therapeutic Targets for Recurrent/Metastatic Anaplastic Thyroid Cancer
Promising Therapeutic Targets for Recurrent/Metastatic Anaplastic Thyroid Cancer
Anaplastic thyroid cancer presents formidable challenges, particularly in cases of recurrence or metastasis. Timely BRAF V...
Current Treatment Options: Uterine Sarcoma
Current Treatment Options: Uterine Sarcoma
The cornerstone of treatment for uterine sarcoma, regardless of histologic type, remains en bloc surgical resection with t...
What is the Optimal Treatment Strategy after Sarcoma R2 Surgery?
What is the Optimal Treatment Strategy after Sarcoma R2 Surgery?
Soft tissue sarcomas (STS) are rare tumours of mesenchymal origin, most commonly occurring in the extremity but also in th...
Treatment of Anemia in Lower-Risk Myelodysplastic Syndrome
Treatment of Anemia in Lower-Risk Myelodysplastic Syndrome
A majority of patients with lower-risk myelodysplastic syndrome (MDS) will present with or develop anemia. Anemia in MDS i...
Neoadjuvant Photodynamic Therapy: An Updated Therapeutic Approach for Non-Melanoma Skin Cancers
Neoadjuvant Photodynamic Therapy: An Updated Therapeutic Approach for Non-Melanoma Skin Cancers
Non-melanoma skin cancers (NMSCs) are the most common malignancy and surgical excision is considered treatment of choice f...
Genetic Predisposition to Sarcoma: What Should Clinicians Know?
Genetic Predisposition to Sarcoma: What Should Clinicians Know?
Pathogenic germline variants in the setting of several associated cancer predisposition syndromes (CPS) may lead to the de...
Post-Radiotherapy Dysphagia in Head and Neck Cancer: Current Management by Speech-Language Pathologists
Post-Radiotherapy Dysphagia in Head and Neck Cancer: Current Management by Speech-Language Pathologists
Dysphagia, difficulty in eating and drinking, remains the most common side effect of radiotherapy treatment for head and n...
Precision Cardio-oncology: Update on Omics-Based Diagnostic Methods
Precision Cardio-oncology: Update on Omics-Based Diagnostic Methods
Cardio-oncology is an emerging interdisciplinary field dedicated to the early detection and treatment of adverse cardiovas...
Circulating Tumor DNA in Diffuse Large B-Cell Lymphoma: from Bench to Bedside?
Circulating Tumor DNA in Diffuse Large B-Cell Lymphoma: from Bench to Bedside?
Diffuse large B-cell lymphoma (DLBCL) is a curable disease with variable outcomes due to underlying heterogeneous clinical...
Immunotherapy for Brain Tumors: Where We Have Been, and Where Do We Go From Here?
Immunotherapy for Brain Tumors: Where We Have Been, and Where Do We Go From Here?
Immunotherapy for glioblastoma (GBM) remains an intensive area of investigation. Given the seismic impact of cancer immuno...
Role of Metastasis-Directed Therapy in Genitourinary Cancers
Role of Metastasis-Directed Therapy in Genitourinary Cancers
The treatment of oligometastatic genitourinary cancers is a rapidly advancing field with ablative radiotherapy as one of t...
HER2-Positive Metastatic Colorectal Cancer
HER2-Positive Metastatic Colorectal Cancer
Targeted treatment strategies are available for human epidermal growth factor receptor 2 (HER2)–positive (amplified ...
Pioneering the Way: The Revolutionary Potential of Antibody–Drug Conjugates in NSCLC
Pioneering the Way: The Revolutionary Potential of Antibody–Drug Conjugates in NSCLC
Despite targeted therapy and immunotherapy being recognized as established frontline treatments for advanced non-small cel...
Ovarian Suppression: Early Menopause and Late Effects
Ovarian Suppression: Early Menopause and Late Effects
Around 90% of breast tumours are diagnosed in the early stage, with approximately 70% being hormone receptor-positive. The...
Evaluation of Homologous Recombination Deficiency in Ovarian Cancer
Homologous recombination deficiency (HRD) is an important biomarker guiding selection of ovarian cancer patients who will ...