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Lung immune incompetency after mild peritoneal sepsis and its partial restoration by type 1 interferon: a mouse model study
Lung immune incompetency after mild peritoneal sepsis and its partial restoration by type 1 interferon: a mouse model study
Sepsis is commonly associated with acute respiratory distress syndrome (ARDS). Although the exaggerated inflammation may d...
β3-Adrenergic receptor antagonism improves cardiac and vascular functions but did not modulate survival in a murine resuscitated septic shock model
β3-Adrenergic receptor antagonism improves cardiac and vascular functions but did not modulate survival in a murine resuscitated septic shock model
Recent findings suggest that β3-adrenergic receptors (β3-AR) could play a role in the hemodynamic regulation, bu...
Safety of flow-controlled ventilation with positive and negative end-expiratory pressure in a swine model of intracranial hypertension
Safety of flow-controlled ventilation with positive and negative end-expiratory pressure in a swine model of intracranial hypertension
Patients with brain damage often require mechanical ventilation. Although lung-protective ventilation is recommended, the ...
Predictors of VILI risk: driving pressure, 4DPRR and mechanical power ratio—an experimental study
Predictors of VILI risk: driving pressure, 4DPRR and mechanical power ratio—an experimental study
Ventilator-induced lung injury (VILI) is one of the side effects of mechanical ventilation during ARDS; a prerequisite for...
Renal venous flow in different regions of the kidney are different and reflecting different etiologies of venous reflux disorders in septic acute kidney injury: a prospective cohort study
Renal venous flow in different regions of the kidney are different and reflecting different etiologies of venous reflux disorders in septic acute kidney injury: a prospective cohort study
Acute kidney injury (AKI) is a frequent complication of sepsis. While impaired renal venous reflux indicates renal congest...
Human liver stem cells and derived extracellular vesicles protect from sepsis-induced acute lung injury and restore bone marrow myelopoiesis in a murine model of sepsis
Human liver stem cells and derived extracellular vesicles protect from sepsis-induced acute lung injury and restore bone marrow myelopoiesis in a murine model of sepsis
Sepsis is a condition with high mortality and morbidity, characterized by deregulation of the immune response against the ...
Effect of fluid and driving pressure on cyclical “on–off” flow of pulmonary microcirculation during mechanical ventilation
Effect of fluid and driving pressure on cyclical “on–off” flow of pulmonary microcirculation during mechanical ventilation
This study aimed to identify the cyclical “on–off” flow of pulmonary microcirculation during inspiration...
Reply to: The pressure gradient for venous return and its derivatives are ambiguous measures
Reply to: The pressure gradient for venous return and its derivatives are ambiguous measures
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, whi...
Target-controlled dialysis for antibiotics (TCD-ABx)
Target-controlled dialysis for antibiotics (TCD-ABx)
Effective antimicrobial therapy is an essential part of intensive care medicine and renal replacement therapy is an import...
Open-lung ventilation versus no ventilation during cardiopulmonary bypass in an innovative animal model of heart transplantation
Open-lung ventilation versus no ventilation during cardiopulmonary bypass in an innovative animal model of heart transplantation
Open-lung ventilation during cardiopulmonary bypass (CPB) in patients undergoing heart transplantation (HTx) is a potentia...
Cerebral capillary oxygen diffusion: exploring the concept of intracapillary hemoglobin conformational changes
Cerebral capillary oxygen diffusion: exploring the concept of intracapillary hemoglobin conformational changes
The mechanisms of oxygen diffusion in brain capillaries have not been fully clarified to date. According to the laws of ph...
Assessment of mitochondrial function and its prognostic role in sepsis: a literature review
Assessment of mitochondrial function and its prognostic role in sepsis: a literature review
Sepsis is characterized by a dysregulated and excessive systemic inflammatory response to infection, associated with vascu...
Predictors of intradialytic hypotension in critically ill patients undergoing kidney replacement therapy: a systematic review
Predictors of intradialytic hypotension in critically ill patients undergoing kidney replacement therapy: a systematic review
This systematic review aims to identify predictors of intradialytic hypotension (IDH) in critically ill patients undergoin...
The development of a C5.0 machine learning model in a limited data set to predict early mortality in patients with ARDS undergoing an initial session of prone positioning
The development of a C5.0 machine learning model in a limited data set to predict early mortality in patients with ARDS undergoing an initial session of prone positioning
Acute Respiratory Distress Syndrome (ARDS) has a high morbidity and mortality. One therapy that can decrease mortality is ...
Thermoregulation and survival during sepsis: insights from the cecal ligation and puncture experimental model
Thermoregulation and survival during sepsis: insights from the cecal ligation and puncture experimental model
Sepsis remains a major global health concern due to its high prevalence and mortality. Changes in body temperature (Tb), s...
A new method to predict return of spontaneous circulation by peripheral intravenous analysis during cardiopulmonary resuscitation: a rat model pilot study
A new method to predict return of spontaneous circulation by peripheral intravenous analysis during cardiopulmonary resuscitation: a rat model pilot study
Enhancing venous return during cardiopulmonary resuscitation (CPR) can lead to better hemodynamics and improved outcome af...
The pressure gradient for venous return and its derivatives are ambiguous measures
The pressure gradient for venous return and its derivatives are ambiguous measures
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, whi...
Lethal versus surviving sepsis phenotypes displayed a partly differential regional expression of neurotransmitters and inflammation and did not modify the blood–brain barrier permeability in female CLP mice
Lethal versus surviving sepsis phenotypes displayed a partly differential regional expression of neurotransmitters and inflammation and did not modify the blood–brain barrier permeability in female CLP mice
Septic encephalopathy is frequent but its pathophysiology is enigmatic. We studied expression of neurotransmitters, inflam...
Mitochondrial DNA in plasma and long-term physical recovery of critically ill patients: an observational study
Mitochondrial DNA in plasma and long-term physical recovery of critically ill patients: an observational study
Post-intensive care syndrome (PICS) poses a notable public health concern, with survivors of critical illness experiencing...
Quantification of pulmonary edema using automated lung segmentation on computed tomography in mechanically ventilated patients with acute respiratory distress syndrome
Quantification of pulmonary edema using automated lung segmentation on computed tomography in mechanically ventilated patients with acute respiratory distress syndrome
Quantification of pulmonary edema in patients with acute respiratory distress syndrome (ARDS) by chest computed tomography...
Cellular oxygen consumption in patients with diabetic ketoacidosis
Cellular oxygen consumption in patients with diabetic ketoacidosis
Diabetic ketoacidosis (DKA) is a potentially life-threatening disorder associated with severe alterations in metabolism an...
An ovine septic shock model of live bacterial infusion
An ovine septic shock model of live bacterial infusion
Escherichia coli is the most common cause of human bloodstream infections and bacterial sepsis/septic shock. However, tran...
Clinical implementation of advanced respiratory monitoring with esophageal pressure and electrical impedance tomography: results from an international survey and focus group discussion
Clinical implementation of advanced respiratory monitoring with esophageal pressure and electrical impedance tomography: results from an international survey and focus group discussion
Popularity of electrical impedance tomography (EIT) and esophageal pressure (Pes) monitoring in the ICU is increasing, but...
A self-regulated expiratory flow device for mechanical ventilation: a bench study
A self-regulated expiratory flow device for mechanical ventilation: a bench study
Unregulated expiratory flow may contribute to ventilator-induced lung injury. The amount of energy dissipated into the lun...
A multimodal characterization of cardiopulmonary resuscitation-associated lung edema
A multimodal characterization of cardiopulmonary resuscitation-associated lung edema
Cardiopulmonary resuscitation-associated lung edema (CRALE) is a phenomenon that has been recently reported in both experi...
HELLO: a protocol for a cluster randomized controlled trial to enhance interpersonal relationships and team cohesion among ICU healthcare professionals
HELLO: a protocol for a cluster randomized controlled trial to enhance interpersonal relationships and team cohesion among ICU healthcare professionals
Mental health symptoms among healthcare professionals (HCP) in intensive care units (ICUs) are a significant concern affec...
Estimation of transpulmonary driving pressure using a lower assist maneuver (LAM) during synchronized ventilation in patients with acute respiratory failure: a physiological study
Estimation of transpulmonary driving pressure using a lower assist maneuver (LAM) during synchronized ventilation in patients with acute respiratory failure: a physiological study
We previously showed in animals that transpulmonary driving pressure (PL) can be estimated during Neurally Adjusted Ventil...
Impact of the transpulmonary pressure on right ventricle impairment incidence during acute respiratory distress syndrome: a pilot study in adults and children
Impact of the transpulmonary pressure on right ventricle impairment incidence during acute respiratory distress syndrome: a pilot study in adults and children
Right ventricle impairment (RVI) is common during acute respiratory distress syndrome (ARDS) in adults and children, possi...
Multiomic biomarkers after cardiac arrest
Multiomic biomarkers after cardiac arrest
Cardiac arrest is a sudden cessation of heart function, leading to an abrupt loss of blood flow and oxygen to vital organs...
Association of corticosteroid therapy with reduced acute kidney injury and lower NET markers in severe COVID-19: an observational study
Association of corticosteroid therapy with reduced acute kidney injury and lower NET markers in severe COVID-19: an observational study
Acute kidney injury (AKI) is common in critical cases of coronavirus disease 2019 (COVID-19) and associated with worse out...
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