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The development of a C5.0 machine learning model in a limited data set to predict early mortality in patients with ARDS undergoing an initial session of prone positioning
The development of a C5.0 machine learning model in a limited data set to predict early mortality in patients with ARDS undergoing an initial session of prone positioning
Acute Respiratory Distress Syndrome (ARDS) has a high morbidity and mortality. One therapy that can decrease mortality is ...
Thermoregulation and survival during sepsis: insights from the cecal ligation and puncture experimental model
Thermoregulation and survival during sepsis: insights from the cecal ligation and puncture experimental model
Sepsis remains a major global health concern due to its high prevalence and mortality. Changes in body temperature (Tb), s...
A new method to predict return of spontaneous circulation by peripheral intravenous analysis during cardiopulmonary resuscitation: a rat model pilot study
A new method to predict return of spontaneous circulation by peripheral intravenous analysis during cardiopulmonary resuscitation: a rat model pilot study
Enhancing venous return during cardiopulmonary resuscitation (CPR) can lead to better hemodynamics and improved outcome af...
The pressure gradient for venous return and its derivatives are ambiguous measures
The pressure gradient for venous return and its derivatives are ambiguous measures
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, whi...
Lethal versus surviving sepsis phenotypes displayed a partly differential regional expression of neurotransmitters and inflammation and did not modify the blood–brain barrier permeability in female CLP mice
Lethal versus surviving sepsis phenotypes displayed a partly differential regional expression of neurotransmitters and inflammation and did not modify the blood–brain barrier permeability in female CLP mice
Septic encephalopathy is frequent but its pathophysiology is enigmatic. We studied expression of neurotransmitters, inflam...
Mitochondrial DNA in plasma and long-term physical recovery of critically ill patients: an observational study
Mitochondrial DNA in plasma and long-term physical recovery of critically ill patients: an observational study
Post-intensive care syndrome (PICS) poses a notable public health concern, with survivors of critical illness experiencing...
Quantification of pulmonary edema using automated lung segmentation on computed tomography in mechanically ventilated patients with acute respiratory distress syndrome
Quantification of pulmonary edema using automated lung segmentation on computed tomography in mechanically ventilated patients with acute respiratory distress syndrome
Quantification of pulmonary edema in patients with acute respiratory distress syndrome (ARDS) by chest computed tomography...
Cellular oxygen consumption in patients with diabetic ketoacidosis
Cellular oxygen consumption in patients with diabetic ketoacidosis
Diabetic ketoacidosis (DKA) is a potentially life-threatening disorder associated with severe alterations in metabolism an...
An ovine septic shock model of live bacterial infusion
An ovine septic shock model of live bacterial infusion
Escherichia coli is the most common cause of human bloodstream infections and bacterial sepsis/septic shock. However, tran...
Clinical implementation of advanced respiratory monitoring with esophageal pressure and electrical impedance tomography: results from an international survey and focus group discussion
Clinical implementation of advanced respiratory monitoring with esophageal pressure and electrical impedance tomography: results from an international survey and focus group discussion
Popularity of electrical impedance tomography (EIT) and esophageal pressure (Pes) monitoring in the ICU is increasing, but...
A self-regulated expiratory flow device for mechanical ventilation: a bench study
A self-regulated expiratory flow device for mechanical ventilation: a bench study
Unregulated expiratory flow may contribute to ventilator-induced lung injury. The amount of energy dissipated into the lun...
A multimodal characterization of cardiopulmonary resuscitation-associated lung edema
A multimodal characterization of cardiopulmonary resuscitation-associated lung edema
Cardiopulmonary resuscitation-associated lung edema (CRALE) is a phenomenon that has been recently reported in both experi...
HELLO: a protocol for a cluster randomized controlled trial to enhance interpersonal relationships and team cohesion among ICU healthcare professionals
HELLO: a protocol for a cluster randomized controlled trial to enhance interpersonal relationships and team cohesion among ICU healthcare professionals
Mental health symptoms among healthcare professionals (HCP) in intensive care units (ICUs) are a significant concern affec...
Estimation of transpulmonary driving pressure using a lower assist maneuver (LAM) during synchronized ventilation in patients with acute respiratory failure: a physiological study
Estimation of transpulmonary driving pressure using a lower assist maneuver (LAM) during synchronized ventilation in patients with acute respiratory failure: a physiological study
We previously showed in animals that transpulmonary driving pressure (PL) can be estimated during Neurally Adjusted Ventil...
Impact of the transpulmonary pressure on right ventricle impairment incidence during acute respiratory distress syndrome: a pilot study in adults and children
Impact of the transpulmonary pressure on right ventricle impairment incidence during acute respiratory distress syndrome: a pilot study in adults and children
Right ventricle impairment (RVI) is common during acute respiratory distress syndrome (ARDS) in adults and children, possi...
Multiomic biomarkers after cardiac arrest
Multiomic biomarkers after cardiac arrest
Cardiac arrest is a sudden cessation of heart function, leading to an abrupt loss of blood flow and oxygen to vital organs...
Association of corticosteroid therapy with reduced acute kidney injury and lower NET markers in severe COVID-19: an observational study
Association of corticosteroid therapy with reduced acute kidney injury and lower NET markers in severe COVID-19: an observational study
Acute kidney injury (AKI) is common in critical cases of coronavirus disease 2019 (COVID-19) and associated with worse out...
An early and stable mouse model of polymyxin-induced acute kidney injury
An early and stable mouse model of polymyxin-induced acute kidney injury
Polymyxins have been revived as a last-line therapeutic option for multi-drug resistant bacteria and continue to account f...
Admission neutrophil-to-lymphocyte ratio to predict mortality in burn patients: a meta-analysis
Admission neutrophil-to-lymphocyte ratio to predict mortality in burn patients: a meta-analysis
The neutrophil-to-lymphocyte ratio (NLR) proves to be a convenient and cost-effective marker with studies showing that a h...
Advancements in understanding the mechanisms of lung–kidney crosstalk
Advancements in understanding the mechanisms of lung–kidney crosstalk
This narrative review delves into the intricate interplay between the lungs and the kidneys, with a focus on elucidating t...
Extracorporeal cardiopulmonary resuscitation: a comparison of two experimental approaches and systematic review of experimental models
Extracorporeal cardiopulmonary resuscitation: a comparison of two experimental approaches and systematic review of experimental models
In patients requiring extracorporeal cardiopulmonary resuscitation (ECPR), there is a need for studies to assess the poten...
Lactated Ringers, albumin and mannitol as priming during cardiopulmonary bypass reduces pulmonary edema in rats compared with hydroxyethyl starch
Lactated Ringers, albumin and mannitol as priming during cardiopulmonary bypass reduces pulmonary edema in rats compared with hydroxyethyl starch
Endothelial disorders with edema formation and microcirculatory perfusion disturbances are common in cardiac surgery with ...
Regional distribution of mechanical strain and macrophage-associated lung inflammation after ventilator-induced lung injury: an experimental study
Regional distribution of mechanical strain and macrophage-associated lung inflammation after ventilator-induced lung injury: an experimental study
Alveolar macrophages activation to the pro-inflammatory phenotype M1 is pivotal in the pathophysiology of Ventilator-Induc...
Nitroglycerin challenge identifies microcirculatory target for improved resuscitation in patients with circulatory shock
Nitroglycerin challenge identifies microcirculatory target for improved resuscitation in patients with circulatory shock
Circulatory shock and multi-organ failure remain major contributors to morbidity and mortality in critically ill patients ...
Elevated level of extracellular vimentin is associated with an increased fibrin formation potential in sepsis: ex vivo swine study
Elevated level of extracellular vimentin is associated with an increased fibrin formation potential in sepsis: ex vivo swine study
Sepsis can lead to coagulopathy and microvascular thrombosis. Prior studies, including ours, reported an increased level o...
Fugitive medical and patient-derived aerosol particle distribution following heparin nebulization in patients with COVID-19 acute hypoxemic respiratory failure: a secondary analysis of the CHARTER study
Fugitive medical and patient-derived aerosol particle distribution following heparin nebulization in patients with COVID-19 acute hypoxemic respiratory failure: a secondary analysis of the CHARTER study
Not applicable.CHARTER Clinical trial Group: David Cosgrave1, Ciara Hanley1, Camilla Giacomini1, John Robert Sheehan1, Pad...
Improving oxygenation in severe ARDS treated with VV-ECMO: comparative efficacy of moderate hypothermia and landiolol in a swine ARDS model
Improving oxygenation in severe ARDS treated with VV-ECMO: comparative efficacy of moderate hypothermia and landiolol in a swine ARDS model
Acute respiratory distress syndrome (ARDS) remains a significant challenge in critical care, with high mortality rates des...
The physiological basis for individualized oxygenation targets in critically ill patients with circulatory shock
The physiological basis for individualized oxygenation targets in critically ill patients with circulatory shock
Circulatory shock, defined as decreased tissue perfusion, leading to inadequate oxygen delivery to meet cellular metabolic...
A pilot feasibility study comparing large language models in extracting key information from ICU patient text records from an Irish population
A pilot feasibility study comparing large language models in extracting key information from ICU patient text records from an Irish population
Artificial intelligence, through improved data management and automated summarisation, has the potential to enhance intens...
Correlation and concordance of carotid Doppler ultrasound and echocardiography with invasive cardiac output measurement in critically ill patients
Correlation and concordance of carotid Doppler ultrasound and echocardiography with invasive cardiac output measurement in critically ill patients
Critical care management heavily relies on accurate cardiac output (CO) measurement. Echocardiography has been a mainstay ...
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