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Use of kidneys from SARS-CoV-2 infected donors
Use of kidneys from SARS-CoV-2 infected donors
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The role of complement in kidney disease
The role of complement in kidney disease
The complement cascade comprises soluble and cell surface proteins and is an important arm of the innate immune system. On...
Gene therapy in a model of nephrotic syndrome
Gene therapy in a model of nephrotic syndrome
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Lymph vessels, Na+ and the teleological science of hypertension
Lymph vessels, Na+ and the teleological science of hypertension
A recent study reports that adenosine A2A receptor-mediated lymphangiogenesis increases lymphatic clearance of excess Na+ ...
Sex differences in renal transporters: assessment and functional consequences
Sex differences in renal transporters: assessment and functional consequences
Mammalian kidneys are specialized to maintain fluid and electrolyte homeostasis. The epithelial transport processes along ...
Author Correction: Regulatory T cells in autoimmune kidney diseases and transplantation
Authors and AffiliationsLaboratory of Experimental Immunology, Immunology Frontier Research Center, Osaka University, Osak...
Interorgan communication networks in the kidney–lung axis
Interorgan communication networks in the kidney–lung axis
The homeostasis and health of an organism depend on the coordinated interaction of specialized organs, which is regulated ...
Designing acute kidney injury clinical trials
Designing acute kidney injury clinical trials
Acute kidney injury (AKI) is a common clinical condition with various causes and is associated with increased mortality. D...
Digital determinants of health: opportunities and risks amidst health inequities
Digital transformation offers unprecedented opportunities for advancing healthcare, but also raises complex ethical and le...
Diagnosis of cardiovascular disease in patients with chronic kidney disease
Diagnosis of cardiovascular disease in patients with chronic kidney disease
Patients with chronic kidney disease (CKD) are at high risk of cardiovascular disease (CVD) and cardiovascular death. Iden...
Targeting IL-1Ra to attenuate fungal infection
Targeting IL-1Ra to attenuate fungal infection
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Role of perivascular cells in kidney homeostasis, inflammation, repair and fibrosis
Role of perivascular cells in kidney homeostasis, inflammation, repair and fibrosis
Perivascular niches in the kidney comprise heterogeneous cell populations, including pericytes and fibroblasts, with disti...
RNA interference for treatment of hypertension
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Primary aldosteronism: molecular medicine meets public health
Primary aldosteronism: molecular medicine meets public health
Primary aldosteronism is the most common single cause of hypertension and is potentially curable when only one adrenal gla...
The realities of diagnosing and managing glomerular disease in low-income countries
The realities of diagnosing and managing glomerular disease in low-income countries
The diagnosis of glomerular disease relies largely on meticulous histological and laboratory investigations that continue ...
Impact of persistent conflict and destabilizing events on dialysis care
Among global destabilizing events, natural disasters often receive widespread attention whereas protracted conflicts and e...
Inequities in kidney health and kidney care
Inequities in kidney health and kidney care
Health inequity refers to the existence of unnecessary and unfair differences in the ability of an individual or community...
Digital health and acute kidney injury: consensus report of the 27th Acute Disease Quality Initiative workgroup
Digital health and acute kidney injury: consensus report of the 27th Acute Disease Quality Initiative workgroup
Acute kidney injury (AKI), which is a common complication of acute illnesses, affects the health of individuals in communi...
Propagation of acute kidney injury
Propagation of acute kidney injury
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Increasing diversity and inclusion in nephrology clinical trials
Increasing diversity and inclusion in nephrology clinical trials
Racial and ethnic minoritized populations are underrepresented in clinical trials in nephrology, but overrepresented in ad...
Reducing preventable acute kidney injury in a hospital setting
Reducing preventable acute kidney injury in a hospital setting
Acute kidney injury (AKI) is a global concern that affects patient outcomes and resource utilization. An effective educati...
Immune-checkpoint inhibition to slow cyst growth
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The genetics and pathogenesis of CAKUT
The genetics and pathogenesis of CAKUT
Congenital anomalies of the kidney and urinary tract (CAKUT) comprise a large variety of malformations that arise from def...
Urinary CXCL9: a biomarker for AIN
Early identification of acute interstitial nephritis (AIN) can enable withdrawal of the causative drug or initiation of th...
Kidney lipid dysmetabolism and lipid droplet accumulation in chronic kidney disease
Kidney lipid dysmetabolism and lipid droplet accumulation in chronic kidney disease
Chronic kidney disease (CKD) is a global health problem with rising incidence and prevalence. Among several pathogenetic m...
Cryopreservation breaks the organ transplant time barrier
Cryopreservation breaks the organ transplant time barrier
In a ground-breaking development, rat kidneys have been cryopreserved for an unprecedented duration of 100 days and subseq...
Historical redlining and kidney failure
Historical redlining and kidney failure
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GFR slope as a surrogate marker for future kidney failure
GFR slope as a surrogate marker for future kidney failure
Kidney failure is a serious but rare consequence of progressive chronic kidney disease. A meta-analysis of individual part...
Inflammation and gut dysbiosis as drivers of CKD–MBD
Inflammation and gut dysbiosis as drivers of CKD–MBD
Two decades ago, Kidney Disease: Improving Global Outcomes coined the term chronic kidney disease–mineral and bone d...
Uropathogen and host responses in pyelonephritis
Uropathogen and host responses in pyelonephritis
Urinary tract infections (UTIs) are among the most common bacterial infections seen in clinical practice. The ascent of UT...
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