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Enhanced antileukemic effect of NKp30b isoform of donor-derived NK cells infused after HLA-haploidentical allogeneic hematopoietic cell transplantation in high-risk AML and MDS
Enhanced antileukemic effect of NKp30b isoform of donor-derived NK cells infused after HLA-haploidentical allogeneic hematopoietic cell transplantation in high-risk AML and MDS
DeWolf S, Tallman MS. How I treat relapsed or refractory AML. Blood. 2020;136:1023–32. https://doi.org/10.1182/blood.20190...
Dynamics of neoantigen-specific T-cells in post-transplant relapse: do leukemia neoantigens elicit immune responses in transplant recipients?
Dynamics of neoantigen-specific T-cells in post-transplant relapse: do leukemia neoantigens elicit immune responses in transplant recipients?
Author notesKayla ParrPresent address: Department of Integrative Immunobiology, Duke University, Durham, NC, USACai ChenPr...
Relationship between age, conditioning intensity, and outcome after allografting in adults age ≥60 years with AML
Relationship between age, conditioning intensity, and outcome after allografting in adults age ≥60 years with AML
Methodological advancements now allow older adults with AML to receive allografts although conflicting data exist regardin...
Hematopoietic stem cell transplantation in inborn errors of metabolism—a retrospective analysis on behalf of the pediatric disease working party from the Brazilian Society of Bone Marrow Transplantation and Cellular Therapy
Hematopoietic stem cell transplantation in inborn errors of metabolism—a retrospective analysis on behalf of the pediatric disease working party from the Brazilian Society of Bone Marrow Transplantation and Cellular Therapy
Hematopoietic stem cell transplantation (HSCT) is an established treatment for selected patients with inborn errors of met...
Identification of the conditions and minimum requirements necessary for the release of autologous fresh CAR T-cell products under hospital exemption: a position paper from the WP-bioproduction of the UNITC consortium
The accessibility of CAR-T cells in centralized production models faces significant challenges, primarily stemming from lo...
Myeloablative conditioning in cord blood transplantation for acute myeloid leukemia patients is efficacious only until age 55
Myeloablative conditioning in cord blood transplantation for acute myeloid leukemia patients is efficacious only until age 55
Umbilical cord blood transplantation (CBT) is accepted as an effective treatment for acute myeloid leukemia (AML), and red...
T cell redirection as a new standard of care for relapsed multiple myeloma: impact on inpatient capacity, financial burden and infrastructural requirements in Germany
Multiple myeloma (MM) is a complex and heterogenous condition and is generally incurable. Although there has been an expan...
Impact of TP53 alteration on allogeneic hematopoietic cell transplantation outcomes for myelodysplastic syndromes
Impact of TP53 alteration on allogeneic hematopoietic cell transplantation outcomes for myelodysplastic syndromes
The poor outcome of TP53 alteration has been reported in myelodysplastic syndrome (MDS) patients. However, the role of all...
“Are They Ready Yet?”: release criteria for autologous CAR T cells
Competing interests AJ: Consulting: Kite/Gilead. Research Support (Institutional...
Incidence, risk factors, and outcomes of transplant-associated thrombotic microangiopathy in pediatric patients after allogeneic hematopoietic cell transplantation: a single-institution prospective study
Incidence, risk factors, and outcomes of transplant-associated thrombotic microangiopathy in pediatric patients after allogeneic hematopoietic cell transplantation: a single-institution prospective study
Transplant-associated thrombotic microangiopathy (TA-TMA) is an increasingly recognized complication in hematopoietic cell...
aGvHDtrackR and cGvHDtrackR: shiny applications for graft versus host disease management and clinical data collection
aGvHDtrackR and cGvHDtrackR: shiny applications for graft versus host disease management and clinical data collection
Graft-versus-host disease (GvHD) is one of the most common and troublesome complications after allogeneic hematopoietic st...
Editorial: Molecular MRD testing in patients with acute myeloid leukemia
Editorial: Molecular MRD testing in patients with acute myeloid leukemia
Heuser M, Freeman SD, Ossenkoppele GJ, Buccisano F, Hourigan CS, Ngai LL, et al. 2021 Update on MRD in acute myeloid leuke...
Defining a lineage-specific chimerism threshold for the use of donor lymphocyte infusions in treating myeloid malignancies
Defining a lineage-specific chimerism threshold for the use of donor lymphocyte infusions in treating myeloid malignancies
Döhner H, Wei AH, Appelbaum FR, Craddock C, DiNardo CD, Dombret H, et al. Diagnosis and management of AML in adults: 2022 ...
Safety and efficacy of the ROCK-2-inhibitor Belumosudil in cGvHD treatment - a retrospective, German-Swiss multicenter real-world data analysis
Safety and efficacy of the ROCK-2-inhibitor Belumosudil in cGvHD treatment - a retrospective, German-Swiss multicenter real-world data analysis
Belumosudil is a first in class ROCK2-inhibitor approved by the FDA for the 3rd line treatment of chronic graft-versus-hos...
Correction: Haploidentical hematopoietic stem cell transplantation for hematologic malignancies: a novel conditioning regimen with anti-T lymphocyte immunoglobulin instead of anti-thymocyte globulin for in vivo T cell depletion
Correction: Haploidentical hematopoietic stem cell transplantation for hematologic malignancies: a novel conditioning regimen with anti-T lymphocyte immunoglobulin instead of anti-thymocyte globulin for in vivo T cell depletion
Open Access This article is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 ...
Letermovir prophylaxis for cytomegalovirus in pediatric patients undergoing allogeneic hematopoietic stem cell transplantation
Letermovir prophylaxis for cytomegalovirus in pediatric patients undergoing allogeneic hematopoietic stem cell transplantation
Ljungman P, Hakki M, Boeckh M. Cytomegalovirus in hematopoietic stem cell transplant recipients. Hematol/Oncol Clin N. Am....
In memory of Kristin Page 1974–2024
In memory of Kristin Page 1974–2024
Our community mourns the recent loss of our colleague and friend, Kristin Pa...
Busulfan conditioning and prognostic impact of jaundice in late-onset sinusoidal obstruction syndrome following allogeneic hematopoietic cell transplantation
Busulfan conditioning and prognostic impact of jaundice in late-onset sinusoidal obstruction syndrome following allogeneic hematopoietic cell transplantation
We thank the patients, the donors, and their families. We also thank the physicians, nurses, pharmacists, physical therapi...
Optimal timing and impact of allogeneic peripheral blood stem cell transplantation in adult T-cell lymphoblastic lymphoma: insights from a large cohort multi-center real-world study in Shanghai
Optimal timing and impact of allogeneic peripheral blood stem cell transplantation in adult T-cell lymphoblastic lymphoma: insights from a large cohort multi-center real-world study in Shanghai
In this real-world study, 153 adult T-cell lymphoblastic lymphoma (T-LBL) patients from sixteen centers in Shanghai were e...
Fludarabine melphalan reduced intensity conditioning vs radiation-based myeloablative conditioning in patients undergoing allogeneic transplantation for acute myeloid leukemia with measurable residual disease
Fludarabine melphalan reduced intensity conditioning vs radiation-based myeloablative conditioning in patients undergoing allogeneic transplantation for acute myeloid leukemia with measurable residual disease
Patients with AML and measurable residual disease (MRD) undergoing allogeneic hematopoietic cell transplantation (HCT) may...
Comparison of fludarabine/melphalan (FM140) with fludarabine/melphalan/BCNU (FBM110) in patients with relapsed/refractory AML undergoing allogeneic hematopoietic cell transplantation – a registry study on behalf of the EBMT Acute Leukemia Working Party
Comparison of fludarabine/melphalan (FM140) with fludarabine/melphalan/BCNU (FBM110) in patients with relapsed/refractory AML undergoing allogeneic hematopoietic cell transplantation – a registry study on behalf of the EBMT Acute Leukemia Working Party
The treatment of relapsed/refractory acute myeloid leukemia (AML) is associated with a dismal prognosis. The allogeneic he...
Anti-CD19 CAR T-cell therapy for primary and secondary CNS lymphomas
Central nervous system lymphomas (CNSL) are a heterogeneous group of generally aggressive tumors whose prognosis varies si...
Immune checkpoint inhibitors therapy for solid organ malignancies after allogeneic hematopoietic stem cell transplantation: a retrospective study from the EBMT Transplant Complications Working Party
Immune checkpoint inhibitors therapy for solid organ malignancies after allogeneic hematopoietic stem cell transplantation: a retrospective study from the EBMT Transplant Complications Working Party
Competing interests JB, CP, WB, AC, JM, MM, NK, PN, AECB, ME, CHA, MK, RR, MS, C...
Quantification of the FLT3 internal tandem duplication is a reliable marker for monitoring measurable residual disease in acute myeloid leukemia with FLT3-ITD mutations
Quantification of the FLT3 internal tandem duplication is a reliable marker for monitoring measurable residual disease in acute myeloid leukemia with FLT3-ITD mutations
Gale RE, Green C, Allen C, Mead AJ, Burnett AK, Hills RK, et al. Medical Research Council Adult Leukaemia Working Party. T...
The EASIX score as a predictor of sinusoidal obstruction syndrome and nonrelapse mortality in paediatric patients receiving allogeneic haematopoietic stem cell transplantation
The EASIX score as a predictor of sinusoidal obstruction syndrome and nonrelapse mortality in paediatric patients receiving allogeneic haematopoietic stem cell transplantation
The endothelial activation and stress index (EASIX) score, calculated as [lactate dehydrogenase (LDH; U/L) ×...
Pre-engraftment bloodstream infection after allogeneic haematopoietic cell transplant: 18-year trends in aetiology, resistance and mortality
Pre-engraftment bloodstream infection after allogeneic haematopoietic cell transplant: 18-year trends in aetiology, resistance and mortality
Bloodstream infections (BSI) are frequent complications after allogeneic hematopoietic cell transplant (HCT). This study r...
Ruxolitinib in acute and chronic graft-versus-host disease: real life long-term experience in a multi-center study for adult and pediatric patients, on behalf of the GETH-TC
Ruxolitinib in acute and chronic graft-versus-host disease: real life long-term experience in a multi-center study for adult and pediatric patients, on behalf of the GETH-TC
Ruxolitinib has been approved for the treatment of adults and pediatric patients ≥12 years with steroid refractory g...
Guinness 0.0: a miracle!
Guinness 0.0: a miracle!
Non credo ai miracoli ne ho visti troppi (I do not believe in m...
Emapalumab for the Treatment of Immune-Mediated Graft Failure after HSCT
Olsson RF, Logan BR, Chaudhury S, Zhu X, Akpek G, Bolwell BJ, et al. Primary graft failure after myeloablative allogeneic ...
Better pre-transplant treatment options for TP53-mutated MDS: cytoreductive or non-cytoreductive therapy?
Better pre-transplant treatment options for TP53-mutated MDS: cytoreductive or non-cytoreductive therapy?
Patients with TP53-mutated myelodysplastic neoplasms (MDS) have unfavorable prognoses; the benefit of cytoreductive treatm...
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