×
Close
註冊
登入
主页
用户
博客
照片
视频
医学图书S馆
医学图书M馆
医学图书D馆
医学术语
群组
活动
用户工具
用户指南
问答
谁看过我
反馈
语言
English
中文
推广
×
Close
CN1699 Our Business - Guide for Agents
分类
Genetics & Heredity
17700
Global Medical University
6303
Allergy
1913
Anatomy & Morphology
1725
Andrology
414
Anesthesia & Intensive Care
1431
Anesthesiology
6333
Audiology & Speech-Language Pathology
374
Behavioral Sciences
111
Biochemical Research Methods
8354
Biochemistry & Molecular Biology
34820
Biodiversity Conservation
392
Biology
10239
Biophysics
11126
Biotechnology & Applied Microbiology
9961
Cardiac & Cardiovascular Systems
35964
Cardiovascular & Respiratory Systems
1691
Cell & Tissue Engineering
792
Cell Biology
12513
Chemistry, Analytical
4751
Chemistry, Applied
13136
Chemistry, Medicinal
9828
Chemistry, Multidisciplinary
21417
Clinical Immunology & Infectious Disease
514
Clinical Medicine
9914
Clinical Neurology
18808
Clinical Psychology & Psychiatry
1770
Critical Care Medicine
3740
Dentistry, Oral Surgery & Medicine
15751
Dermatology
8074
Developmental Biology
7708
Ecology
665
Education, Scientific Disciplines
2258
Emergency Medicine
4869
Endocrinology, Metabolism & Nutrition
28757
Engineering, Biomedical
4275
Entomology
492
Environmental Medicine & Public Health
5644
Evolutionary Biology
295
Gastroenterology & Hepatology
14026
General & Internal Medicine
8199
Geriatrics & Gerontology
5771
Gerontology
369
Health Care Sciences & Services
18728
Health Policy & Services
690
Hematology
6123
Immunology
29607
Infectious Diseases
16117
Integrative & Complementary Medicine
3353
Medical Ethics
1335
Medical Informatics
2853
Medical Laboratory Technology
433
Medicine, General & Internal
50422
Medicine, Legal
623
Medicine, Research & Experimental
21642
Microbiology
27649
Mycology
0
Nanoscience & Nanotechnology
6257
Neuroimaging
1573
Neurology
5481
Neurosciences
46796
Nursing
10793
Nutrition & Dietetics
8775
Obstetrics & Gynecology
9495
Oncology
61033
Ophthalmology
11625
Optics
5554
Orthopedics
13280
Orthopedics, Rehabilitation & Sports Medicine
2120
Otolaryngology
1729
Otorhinolaryngology
5566
Parasitology
1188
Pathology
5685
Pediatrics
24787
Peripheral Vascular Disease
5416
Pharmacology & Pharmacy
42172
Pharmacology/Toxicology
14412
Physiology
10025
Polymer Science
736
Primary Health Care
945
Psychiatry
23679
Psychology
5846
Psychology, Applied
123
Psychology, Biological
415
Psychology, Clinical
927
Psychology, Developmental
237
Psychology, Educational
159
Psychology, Experimental
154
Psychology, Mathematical
0
Psychology, Multidisciplinary
1713
Psychology, Psychoanalysis
41
Psychology, Social
124
Public Health & Health Care Science
2448
Public, Environmental & Occupational Health
31350
Quantum Science & Technology
0
Radiology, Nuclear Medicine & Imaging
14572
Radiology, Nuclear Medicine & Medical Imaging
9158
Rehabilitation
3325
Remote Sensing
0
Reproductive Biology
3455
Reproductive Medicine
1390
Research/Laboratory Medicine & Medical Technology
4650
Respiratory System
8511
Rheumatology
6939
Social Sciences, Biomedical
1342
Substance Abuse
3054
Surgery
39525
Toxicology
4899
Transplantation
957
Tropical Medicine
314
Urology & Nephrology
15272
Veterinary Sciences
35
Virology
2720
Zoology
0
渠道
EPIGENETICS & CHROMATIN
153
Genetics
5
NEJM Genetics
3
Medrxiv - Genetic And Genomic Medicine
2416
CANCER GENE THERAPY
474
CHROMOSOMA
74
CLINICAL GENETICS
118
CURRENT GENETICS
120
CURRENT OPINION IN GENETICS & DEVELOPMENT
306
EPIGENOMICS
22
EPILEPSIA
211
FRONTIERS IN GENETICS
6134
GENE THERAPY
223
GENETICS IN MEDICINE
104
GENOME MEDICINE
402
GENOMICS PROTEOMICS & BIOINFORMATICS
215
HUMAN GENETICS
410
HUMAN MUTATION
121
JOURNAL OF HUMAN GENETICS
349
JOURNAL OF MEDICAL GENETICS
489
NATURE REVIEWS GENETICS
397
NPJ GENOMIC MEDICINE
210
ORPHANET JOURNAL OF RARE DISEASES
1021
ANNALS OF HUMAN GENETICS
24
CYTOGENETIC AND GENOME RESEARCH
97
G3-GENES GENOMES GENETICS
19
GENETIC EPIDEMIOLOGY
30
HUMAN GENOMICS
311
HUMAN HEREDITY
33
INTERNATIONAL JOURNAL OF IMMUNOGENETICS
23
JOURNAL OF EVOLUTIONARY BIOLOGY
120
JOURNAL OF GENETIC COUNSELING
152
PSYCHIATRIC GENETICS
137
EGYPTIAN JOURNAL OF MEDICAL HUMAN GENETICS
365
FORENSIC SCIENCE INTERNATIONAL GENETICS SUPPLEMENT SERIES
17
GENETICS AND MOLECULAR RESEARCH
25
GLOBAL MEDICAL GENETICS
159
INTERNATIONAL JOURNAL OF NEONATAL SCREENING
89
JOURNAL OF COMMUNITY GENETICS
199
NON-CODING RNA
125
FUNCTIONAL & INTEGRATIVE GENOMICS
617
GENETICA
99
IMMUNOGENETICS
138
JOURNAL OF APPLIED GENETICS
262
JOURNAL OF GENETICS
193
RUSSIAN JOURNAL OF GENETICS
489
SCI时时刷
search
全部
推荐
+
Transcriptional silencing in Saccharomyces cerevisiae: known unknowns
Transcriptional silencing in Saccharomyces cerevisiae is a persistent and highly stable form of gene repression. It involv...
Epigenetics & Chromatin
comment
0
thumb_up
0
The role of hexokinases in epigenetic regulation: altered hexokinase expression and chromatin stability in yeast
Human hexokinase 2 (HK2) plays an important role in regulating Warburg effect, which metabolizes glucose to lactate acid e...
Epigenetics & Chromatin
comment
0
thumb_up
0
Transcriptional regulation mechanism of PARP1 and its application in disease treatment
Poly (ADP-ribose) polymerase 1 (PARP1) is a multifunctional nuclear enzyme that catalyzes poly-ADP ribosylation in eukaryo...
Epigenetics & Chromatin
comment
0
thumb_up
0
DNA methylation correlates of chronological age in diverse human tissue types
While the association of chronological age with DNA methylation (DNAm) in whole blood has been extensively studied, the ti...
Epigenetics & Chromatin
comment
0
thumb_up
0
Long-term exposure to diesel exhaust particles induces concordant changes in DNA methylation and transcriptome in human adenocarcinoma alveolar basal epithelial cells
Diesel exhaust particles (DEP), which contain hazardous compounds, are emitted during the combustion of diesel. As approxi...
Epigenetics & Chromatin
comment
0
thumb_up
0
The role of ribosomal DNA methylation in embryonic development, aging and diseases
The ribosomal DNA (rDNA) constitutes a remarkably conserved DNA sequence within species, located in the area of the nucleo...
Epigenetics & Chromatin
comment
0
thumb_up
0
CUT&Tag applied to zebrafish adult tail fins reveals a return of embryonic H3K4me3 patterns during regeneration
Regenerative potential is governed by a complex process of transcriptional reprogramming, involving chromatin reorganizati...
Epigenetics & Chromatin
comment
0
thumb_up
0
CREdb: A comprehensive database of Cis-Regulatory Elements and their activity in human cells and tissues
Cis-regulatory elements (CREs) play a pivotal role in gene expression regulation, allowing cells to serve diverse function...
Epigenetics & Chromatin
comment
0
thumb_up
0
Imprinted DNA methylation of the H19 ICR is established and maintained in vivo in the absence of Kaiso
Paternal allele-specific DNA methylation of the imprinting control region (H19 ICR) controls genomic imprinting at the Igf...
Epigenetics & Chromatin
comment
0
thumb_up
0
Native and tagged CENP-A histones are functionally inequivalent
Over the past several decades, the use of biochemical and fluorescent tags has elucidated mechanistic and cytological proc...
Epigenetics & Chromatin
comment
0
thumb_up
0
From compartments to loops: understanding the unique chromatin organization in neuronal cells
The three-dimensional organization of the genome plays a central role in the regulation of cellular functions, particularl...
Epigenetics & Chromatin
comment
0
thumb_up
0
Su(Hw) interacts with Combgap to establish long-range chromatin contacts
Insulator-binding proteins (IBPs) play a critical role in genome architecture by forming and maintaining contact domains. ...
Epigenetics & Chromatin
comment
0
thumb_up
0
Chromatin profiling and state predictions reveal insights into epigenetic regulation during early porcine development
Given their physiological similarities to humans, pigs are increasingly used as model organisms in human-oriented biomedic...
Epigenetics & Chromatin
comment
0
thumb_up
0
Roles of post-translational modifications of UHRF1 in cancer
UHRF1 as a member of RING-finger type E3 ubiquitin ligases family, is an epigenetic regulator with five structural domains...
Epigenetics & Chromatin
comment
0
thumb_up
0
Prenatal nicotine exposure leads to epigenetic alterations in peripheral nervous system signaling genes in the testis of the rat
Prenatal nicotine exposure (PNE) has been documented to cause numerous deleterious effects on fetal development. However, ...
Epigenetics & Chromatin
comment
0
thumb_up
0
The probability of chromatin to be at the nuclear lamina has no systematic effect on its transcription level in fruit flies
Multiple studies have demonstrated a negative correlation between gene expression and positioning of genes at the nuclear ...
Epigenetics & Chromatin
comment
0
thumb_up
0
Reinforcement of repressive marks in the chicken primordial germ cell epigenetic signature: divergence from basal state resetting in mammals
In mammals, primordial germ cells (PGCs), the embryonic precursors of the germline, arise from embryonic or extra-embryoni...
Epigenetics & Chromatin
comment
0
thumb_up
0
Histone proteoform analysis reveals epigenetic changes in adult mouse brown adipose tissue in response to cold stress
Regulation of the thermogenic response by brown adipose tissue (BAT) is an important component of energy homeostasis with ...
Epigenetics & Chromatin
comment
0
thumb_up
0
Analysis of long-range chromatin contacts, compartments and looping between mouse embryonic stem cells, lens epithelium and lens fibers
Nuclear organization of interphase chromosomes involves individual chromosome territories, “open” and “c...
Epigenetics & Chromatin
comment
0
thumb_up
0
The N-terminal dimerization domains of human and Drosophila CTCF have similar functionality
CTCF is highly likely to be the ancestor of proteins that contain large clusters of C2H2 zinc finger domains, and its cons...
Epigenetics & Chromatin
comment
0
thumb_up
0
Transcriptionally active chromatin loops contain both ‘active’ and ‘inactive’ histone modifications that exhibit exclusivity at the level of nucleosome clusters
Chromatin state is thought to impart regulatory function to the underlying DNA sequence. This can be established through h...
Epigenetics & Chromatin
comment
0
thumb_up
0
Incorporation of the histone variant H2A.Z counteracts gene silencing mediated by H3K27 trimethylation in Fusarium fujikuroi
Fusarium fujikuroi is a pathogen of rice causing diverse disease symptoms such as ‘bakanae’ or stunting, most ...
Epigenetics & Chromatin
comment
0
thumb_up
0
TP63–TRIM29 axis regulates enhancer methylation and chromosomal instability in prostate cancer
Prostate adenocarcinoma (PRAD) is the second leading cause of cancer-related deaths in men. High variability in DNA methyl...
Epigenetics & Chromatin
comment
0
thumb_up
0
Intrafamily heterooligomerization as an emerging mechanism of methyltransferase regulation
Protein and nucleic acid methylation are important biochemical modifications. In addition to their well-established roles ...
Epigenetics & Chromatin
comment
0
thumb_up
0
Research progress of SWI/SNF complex in breast cancer
In the past decade, numerous epigenetic mechanisms have been discovered to be associated with cancer. The mammalian SWI/SN...
Epigenetics & Chromatin
comment
0
thumb_up
0
A low-input high resolution sequential chromatin immunoprecipitation method captures genome-wide dynamics of bivalent chromatin
Bivalent chromatin is an exemplar of epigenetic plasticity. This co-occurrence of active-associated H3K4me3 and inactive-a...
Epigenetics & Chromatin
comment
0
thumb_up
0
Role of sex in immune response and epigenetic mechanisms
The functioning of the human immune system is highly dependent on the sex of the individual, which comes by virtue of sex ...
Epigenetics & Chromatin
comment
0
thumb_up
0
Chromatin accessibility and cell cycle progression are controlled by the HDAC-associated Sin3B protein in murine hematopoietic stem cells
Blood homeostasis requires the daily production of millions of terminally differentiated effector cells that all originate...
Epigenetics & Chromatin
comment
0
thumb_up
0
Folate deficiency reduced aberrant level of DOT1L-mediated histone H3K79 methylation causes disruptive SHH gene expression involved in neural tube defects
Neural tube defects (NTDs) are one of the most severe congenital abnormalities characterized by failures of the neural tub...
Epigenetics & Chromatin
comment
0
thumb_up
0
O-GlcNAcylation: the sweet side of epigenetics
Histones display a wide variety of post-translational modifications, including acetylation, methylation, and phosphorylati...
Epigenetics & Chromatin
comment
0
thumb_up
0
阅读更多
Modal title
×
Modal title
×
分享
登入
Global News and Health Forum
Join Now!
馬上登入
記住我
忘記密碼?
或者使用
Linkedin