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How can we optimise learning from trials in child and adolescent mental health?
How can we optimise learning from trials in child and adolescent mental health?
Improving child and adolescent mental health requires the careful development and rigorous testing of interventions and de...
Universal prevention of depression at schools: dead end or challenging crossroad?
Universal prevention of depression at schools: dead end or challenging crossroad?
Universal school programmes aimed at the prevention of depression and other common mental health problems in adolescents a...
School-based mindfulness training in early adolescence: what works, for whom and how in the MYRIAD trial?
School-based mindfulness training in early adolescence: what works, for whom and how in the MYRIAD trial?
WHAT IS ALREADY KNOWN ON THIS TOPICThere are systematic reviews and meta-analyses demonstrating the potential effectivenes...
Building trust in artificial intelligence and new technologies in mental health
Building trust in artificial intelligence and new technologies in mental health
In 2019, the Topol review was published on behalf of the secretary of state for health and social care in the UK, preparin...
Economic threshold analysis of delivering a task-sharing treatment for common mental disorders at scale: the Friendship Bench, Zimbabwe
Economic threshold analysis of delivering a task-sharing treatment for common mental disorders at scale: the Friendship Bench, Zimbabwe
Analytical approachThe threshold analysis was undertaken within a ‘cost-utility’ framework with treatment benefit quantifi...
Serum folate deficiency and the risks of dementia and all-cause mortality: a national study of old age
Serum folate deficiency and the risks of dementia and all-cause mortality: a national study of old age
BackgroundWith ageing, serum concentrations of folate decrease,1 leading to a higher prevalence of a threshold-based medic...
Dose-effect meta-analysis for psychopharmacological interventions using randomised data
Dose-effect meta-analysis for psychopharmacological interventions using randomised data
IntroductionSynthesis of evidence provided by randomised controlled trials (RCTs) is commonly used to develop clinical gui...
Promoting inclusivity by ensuring that all patients with mental health issues are offered research opportunities in the NHS
Promoting inclusivity by ensuring that all patients with mental health issues are offered research opportunities in the NHS
Research-active clinical services have lower mortality rates and produce higher quality care outcomes, however, recruiting...
Using computerised adaptive tests to screen for perinatal depression in underserved women of colour
Using computerised adaptive tests to screen for perinatal depression in underserved women of colour
If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Cleara...
Prevalence of childhood mental disorders in high-income countries: a systematic review and meta-analysis to inform policymaking
Prevalence of childhood mental disorders in high-income countries: a systematic review and meta-analysis to inform policymaking
BackgroundMental disorders typically start in childhood and adolescence (hereafter childhood) and significantly interfere ...
Methods and efficacy of social support interventions in preventing suicide: a systematic review and meta-analysis
Methods and efficacy of social support interventions in preventing suicide: a systematic review and meta-analysis
BackgroundSuicide is a global public and mental health problem. According to the WHO, 703 000 people die by suicide every ...
Increasing the clinical interpretability of PHQ-9 through equipercentile linking with health utility values by EQ-5D-3L
Increasing the clinical interpretability of PHQ-9 through equipercentile linking with health utility values by EQ-5D-3L
In our recent paper,1 we presented the results of the equipercentile linking analysis between the Patient Health Questionn...
Guidelines to understand and compute the number needed to treat
Guidelines to understand and compute the number needed to treat
IntroductionThe number needed to treat (NNT) refers to the average number of patients needed to treat to obtain one respon...
Impact of COVID-19 on telepsychiatry at the service and individual patient level across two UK NHS mental health Trusts
Impact of COVID-19 on telepsychiatry at the service and individual patient level across two UK NHS mental health Trusts
BackgroundTelepsychiatry is the delivery of psychiatric assessments or follow-up interviews from a distance using technolo...
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When we took the editorship of Evidence-Based Mental Health (EBMH) at the end of 2013, we set two main objectives: to prom...
How can we estimate QALYs based on PHQ-9 scores? Equipercentile linking analysis of PHQ-9 and EQ-5D
How can we estimate QALYs based on PHQ-9 scores? Equipercentile linking analysis of PHQ-9 and EQ-5D
IntroductionQuality-adjusted life years (QALYs) have been increasingly used in general medicine and in psychiatry to evalu...