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Trichotillomania: a perspective synthesised from neuroscience and lived experience
Trichotillomania (trich) is a hair-pulling disorder, and is one of a family of disorders called body-focused repetitive be...
Impact of the COVID-19 pandemic on antipsychotic prescribing in individuals with autism, dementia, learning disability, serious mental illness or living in a care home: a federated analysis of 59 million patients primary care records in situ using OpenSAFELY
BackgroundIn March 2020, the UK went into its first national lockdown following the outbreak of the SARS-CoV-2 pandemic. S...
Understanding the causal relationships of attention-deficit/hyperactivity disorder with mental disorders and suicide attempt: a network Mendelian randomisation study
BackgroundAttention-deficit/hyperactivity disorder (ADHD) is a lifespan neurodevelopmental condition characterised by the ...
Ecological monitoring of physical activity, emotions and daily life activities in schizophrenia: the DiAPAson study
WHAT IS ALREADY KNOWN ON THIS TOPICPrevious studies in this area have generally found that patients with schizophrenia spe...
Depressive symptom networks in the UK general adolescent population and in those looked after by local authorities
WHAT IS ALREADY KNOWN ON THIS TOPICAdolescence is a critical developmental period marked by significant psychobiological t...
Prevalence of sleep disorder diagnoses and sleep medication prescriptions in individuals with ADHD across the lifespan: a Swedish nationwide register-based study
BackgroundAttention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental condition characterised by impairing lev...
Genetic liability to bipolar disorder and onset of postpartum mental disorders
IntroductionChildbirth triggers a broad range of diagnoses jointly defined as postpartum mental disorders (PMDs),1 but imm...
Qualitative evidence regarding the experience of receiving and providing care for mental health conditions in non-specialist settings in low-income and middle-income countries: a systematic review of reviews
Given this, the objective of this review is to synthesise qualitative evidence on the experiences of receiving and providi...
Development and validation of a dementia risk score in the UK Biobank and Whitehall II cohorts
BackgroundAn estimated 50 million individuals are currently living with dementia worldwide.1 With the number of dementia c...
Effects of a culturally adapted counselling service for low-income ethnic minorities experiencing mental distress: a pragmatic randomised clinical trial
WHAT IS ALREADY KNOWN ON THIS TOPICWHAT THIS STUDY ADDSIn this randomised clinical trial of 120 participants with mild and...
Depression, violence and socioeconomic outcomes among refugees in East Africa: evidence from a multicountry representative survey
WHAT IS ALREADY KNOWN ON THIS TOPICPrevious studies have found that refugees are more likely to experience depression, anx...
Evaluation of telepsychiatry during the COVID-19 pandemic across service users, carers and clinicians: an international mixed-methods study
BackgroundTelepsychiatry is defined as ‘the delivery of psychiatric assessments or follow-up interviews from a distance us...
Living alone and mental health: parallel analyses in UK longitudinal population surveys and electronic health records prior to and during the COVID-19 pandemic
IntroductionMore people than ever are living alone.1 For instance, recent estimates from the UK suggest that over 25% of h...
Associations between air pollution and mental health service use in dementia: a retrospective cohort study
IntroductionDementia is now the leading cause of death in the UK, with an estimated 850 000 individuals living with the co...
Correspondence on population health surveys and screening tools for depressive disorders: aims and uses by Arias de la Torre et al
Arias de la Torre et al argue in ‘Population health surveys and screening tools for depressive disorders: aims and uses’ t...
Predictors of positive patient-reported outcomes from 'Early Intervention in Psychosis: a national cross-sectional study
BackgroundPsychotic disorders are severe mental health conditions with wide-ranging consequences including poor physical h...
Self-Help Plus for refugees and asylum seekers: an individual participant data meta-analysis
IntroductionIn 2022, more than 101 million people were forcibly displaced worldwide because of war, armed conflict, persec...
Prescription amphetamines in people with opioid use disorder and co-occurring psychostimulant use disorder initiating buprenorphine: an analysis of treatment retention and overdose risk
WHAT IS ALREADY KNOWN ON THIS TOPICPrescription amphetamines (PAs) are useful to treat attention-deficit and hyperactivity...
Cause-specific excess mortality after first diagnosis of bipolar disorder: population-based cohort study
WHAT IS ALREADY KNOWN ON THIS TOPICHOW THIS STUDY MIGHT AFFECT RESEARCH, PRACTICE OR POLICYBackgroundBipolar affective dis...
Improving mental healthcare access and experience for people from minority ethnic groups: an England-wide multisite experience-based codesign (EBCD) study
WHAT IS ALREADY KNOWN ON THIS TOPICHOW THIS STUDY MIGHT AFFECT RESEARCH, PRACTICE OR POLICYSubstantial change is needed to...
Patients requesting and receiving euthanasia for psychiatric disorders in the Netherlands
BackgroundAn increasing number of countries legally permit the performance of euthanasia and assisted suicide (EAS) for ps...
Risk of death by suicide following self-harm presentations to healthcare: development and validation of a multivariable clinical prediction rule (OxSATS)
WHAT IS ALREADY KNOWN ON THIS TOPICSelf-harm is associated with a 1-year risk of suicide that is 20 times higher than the ...
Physical injuries as triggers for self-harm: a within-individual study of nearly 250 000 injured people with a major psychiatric disorder
WHAT IS ALREADY KNOWN ON THIS TOPICWe identified one relevant study conducted in rural China using monthly data that repor...
Positive affect training to reduce mental health problems during the COVID-19 pandemic: a proof-of-concept randomised clinical trial
WHAT IS ALREADY KNOWN ON THIS TOPICPositive affect training aims to reduce anhedonia by promoting awareness of positive af...
Population health surveys and screening tools for depressive disorders: aims and uses
The article by Fischer and colleagues,1 based on data from the second wave of the European Health Interview Survey (EHIS-2...
Predicting outcomes at the individual patient level: what is the best method?
IntroductionClinical prediction models aim to predict healthcare outcomes based on a set of baseline variables (predictors...
Assessing violence risk in first-episode psychosis: external validation, updating and net benefit of a prediction tool (OxMIV)
WHAT IS ALREADY KNOWN ON THIS TOPICViolence perpetration is an important adverse outcome for some individuals presenting t...
Associations between antipsychotics and the risk of incident cardiovascular diseases in individuals with schizophrenia: a nested case-control study
WHAT IS ALREADY KNOWN ON THIS TOPICIndividuals with schizophrenia are at a higher risk for cardiovascular disease (CVD) mo...
New living evidence resource of human and non-human studies for early intervention and research prioritisation in anxiety, depression and psychosis
ProblemAnxiety, depression and psychosis are among the top leading causes of the global burden of disease.1 Current preven...
Effectiveness of a mental health stepped-care programme for healthcare workers with psychological distress in crisis settings: a multicentre randomised controlled trial
WHAT IS ALREADY KNOWN ON THIS TOPICWHAT THIS STUDY ADDSThis is the first randomised controlled trial to provide evidence o...
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