SCI时时刷

search
PGC-1β modulates catabolism and fiber atrophy in the fasting-response of specific skeletal muscle beds
ObjectiveSkeletal muscle is a pivotal organ for the coordination of systemic metabolism, constituting one of the largest s...
Insulin and IGF-1 elicit robust transcriptional regulation to modulate autophagy in astrocytes
ObjectiveInsulin is a principal metabolic hormone. It regulates a plethora of metabolic pathways in peripheral tissues. Th...
T3 and glucose increase expression of phosphoenolpyruvate carboxykinase (PCK1) leading to increased β-cell proliferation
ObjectivesThyroid hormone (T3) and high glucose concentrations are critical components of β-cell maturation and function. ...
Optimal method for detecting cervical lymph node metastasis from papillary thyroid cancer
Optimal method for detecting cervical lymph node metastasis from papillary thyroid cancer
Papillary thyroid cancer (PTC) is often accompanied by cervical lymph node metastases (LNM). This study compared the diagn...
Serum neurofilament light chain: a novel biomarker for early diabetic sensorimotor polyneuropathy
Serum neurofilament light chain: a novel biomarker for early diabetic sensorimotor polyneuropathy
No established blood-based biomarker exists to monitor diabetic sensorimotor polyneuropathy (DSPN) and evaluate treatment ...
Bioinformatic tools for epitranscriptomics
Bioinformatic tools for epitranscriptomics
The epitranscriptome, defined as RNA modifications that do not involve alterations in the nucleotide sequence, is a popula...
Arterial Remodeling: The Role of Mitochondrial Metabolism in Vascular Smooth Muscle Cells
Arterial Remodeling: The Role of Mitochondrial Metabolism in Vascular Smooth Muscle Cells
Arterial remodeling is a common pathological foundation of cardiovascular diseases such as atherosclerosis, vascular reste...
The cell polarity protein Scribble is downregulated by the water channel aquaporin-5 in breast cancer cells
The cell polarity protein Scribble is downregulated by the water channel aquaporin-5 in breast cancer cells
Breast carcinomas originate from cells in the terminal duct-lobular unit. Carcinomas are associated with increased cell pr...
Interaction of sex and diabetes on the association between hemoglobin glycation index, hemoglobin A1c and serum uric acid
Interaction of sex and diabetes on the association between hemoglobin glycation index, hemoglobin A1c and serum uric acid
Hemoglobin glycation index (HGI), which is calculated by blood glucose and hemoglobin A1c(HbA1c), reflects the individual ...
Type 1 diabetes outpatient care and treatment effectiveness during COVID-19: A single-center cohort study
The coronavirus disease 2019 (COVID-19) pandemic has caused a major healthcare crisis worldwide.1., 2. Diabetes has been i...
Simplifying therapy to assure glycemic control and engagement (STAGE) in poorly-controlled diabetes: A pilot study
In this single-arm pilot study, we demonstrated feasibility and acceptability of an insulin simplification intervention in...
Trabecular Bone Score (TBS) Cross-Calibration for GE Prodigy and iDXA Scanners
Available online 5 December 2022Author links open overlay panelAbstractDual-energy X-ray absorptiometry (DXA) is used for ...
Ethnicity and Fracture Risk Stratification from Trabecular Bone Score in Canadian Women: The Manitoba BMD Registry
Lumbar spine trabecular bone score (TBS), a grey-level texture measure derived from spine dual-energy x-ray absorptiometry...
Why Do So Many People with Type 2 Diabetes Who Take Insulin Have Lipohypertrophy? Fate or Educational Deficiencies?
Why Do So Many People with Type 2 Diabetes Who Take Insulin Have Lipohypertrophy? Fate or Educational Deficiencies?
Cutaneous lipohypertrophy (LH) is a thickened, “rubbery” lesion in the subcutaneous tissue following multiple ...
Primary aldosteronism is a clinical issue that should not be underestimated anymore
Primary aldosteronism is a clinical issue that should not be underestimated anymore
Funder JW, Carey RM, Mantero F, Murad MH, Reincke M, Shibata H, Stowasser M, Young WF Jr (2016) The management of primary ...
Response letter to “sarcopenia, osteoporosis and fractures: what we see”
Response letter to “sarcopenia, osteoporosis and fractures: what we see”
Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USARebekah J. Harr...
Sarcopenia, osteoporosis, and fractures: what we see mainly depends on how we look?
Sarcopenia, osteoporosis, and fractures: what we see mainly depends on how we look?
Harris RJ, Parimi N, Cawthon PM, Strotmeyer ES, Boudreau RM, Brach JS et al (2022) Associations of components of sarcopeni...
Frailty and risk of subsequent fracture among older adults presenting to hospital with a minimal trauma fracture
Frailty and risk of subsequent fracture among older adults presenting to hospital with a minimal trauma fracture
We investigated frailty and refracture risk among older adults with a minimal trauma fracture. After adjusting fo...
Role of biological effective dose for prediction of endocrine remission in acromegaly patients treated with stereotactic radiosurgery
Role of biological effective dose for prediction of endocrine remission in acromegaly patients treated with stereotactic radiosurgery
Stereotactic radiosurgery (SRS) can be used in acromegaly patients to achieve endocrine remission. In this study we evalua...
Metabolic dysfunction-associated fatty liver disease and implications for cardiovascular risk and disease prevention
Metabolic dysfunction-associated fatty liver disease and implications for cardiovascular risk and disease prevention
The newly proposed term “metabolic dysfunction-associated fatty liver disease” (MAFLD) is replacing the old te...
Role of apolipoprotein C1 in lipoprotein metabolism, atherosclerosis and diabetes: a systematic review
Role of apolipoprotein C1 in lipoprotein metabolism, atherosclerosis and diabetes: a systematic review
Apolipoprotein C1 (apoC1) is a small size apolipoprotein whose exact role is not totally clarified but which seems to modu...
Benefits of successful percutaneous coronary intervention in chronic total occlusion patients with diabetes
Benefits of successful percutaneous coronary intervention in chronic total occlusion patients with diabetes
Diabetes was commonly seen in chronic total occlusion (CTO) patients but data regarding the impact of successful percutane...