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Characterization of Calea ternifolia and its Adulterant Chromolaena odorata Using Macro-Microscopy, HPTLC and UHPLC-UV–MS
Characterization of Calea ternifolia and its Adulterant Chromolaena odorata Using Macro-Microscopy, HPTLC and UHPLC-UV–MS
Calea ternifolia Kunth (syn. C. zacatechichi Schltdl.), Asteraceae, commonly known in English as dream herb, bitter-grass,...
Safflor Yellow A Protects Beas-2B Cells Against LPS-Induced Injury via Activating Nrf2
Safflor Yellow A Protects Beas-2B Cells Against LPS-Induced Injury via Activating Nrf2
Acute lung injury and its severe form acute respiratory distress syndrome are lethal lung diseases. So far, effective ther...
Current Prospects and Clinical Status of Microalgae Derived Chemotherapeutics
Current Prospects and Clinical Status of Microalgae Derived Chemotherapeutics
Globally, despite clinical advancements made over a decade, cancer remains a prominent cause of death. Numerous drugs have...
Determination of Sennosides in Cassia angustifolia by HPLC–DAD
Determination of Sennosides in Cassia angustifolia by HPLC–DAD
A methodology based on HPLC for the determination and quantification of sennosides in the extracts of Cassia angustifolia ...
Paeonol Inhibits Glioma Growth In Vivo and In Vitro by Inducing Apoptosis and Cell Cycle Arrest
Paeonol Inhibits Glioma Growth In Vivo and In Vitro by Inducing Apoptosis and Cell Cycle Arrest
Glioma is the most common primary brain tumors with diverse biological behavior. Paeonol, a phenolic component extracted f...
Aromatic Compounds from Malus rockii and Their Lipid-Lowering Activities
Aromatic Compounds from Malus rockii and Their Lipid-Lowering Activities
A new dibenzofuran, 2-hydroxy-4,5-dimethoxydibenzofuran, together with seven known aromatic compounds 2-hydroxy-4-methoxyd...
Effect of Ellipticine in Glucocorticoid-Induced Osteoporosis: In Silico and In Vivo Analyses
Effect of Ellipticine in Glucocorticoid-Induced Osteoporosis: In Silico and In Vivo Analyses
Glucocorticoids cause secondary osteoporosis, which leads to considerable morbidity from fractures. The antiosteoporosis a...
Structure Elucidation of a Methylated Flavan-3-ol and Dimeric Prodelphinidin from Stryphnodendron adstringens
Structure Elucidation of a Methylated Flavan-3-ol and Dimeric Prodelphinidin from Stryphnodendron adstringens
The new methylated polyphenols, 4’-O-methyl-ent-epigallocatechin and 4’-O-methyl-epigallocatechin-3-O-gallate-...
Inhibitory Effects and Related Molecular Mechanisms of Huanglian-Ganjiang Combination Against H1N1 Influenza Virus
Inhibitory Effects and Related Molecular Mechanisms of Huanglian-Ganjiang Combination Against H1N1 Influenza Virus
Influenza is an infectious acute respiratory disease with complications and a high mortality rate; the effective medicines...
(R)-(+)-Rosmarinic Acid as an Inhibitor of Herpes and Dengue Virus Replication: an In Silico Assessment
(R)-(+)-Rosmarinic Acid as an Inhibitor of Herpes and Dengue Virus Replication: an In Silico Assessment
Since ancient times, viruses such as dengue, herpes, Ebola, AIDS, influenza, chicken meat, and SARS have been roaming arou...
Statistical Optimization of Spray-Dried Extract from Leaves of Croton blanchetianus: Simplex Centroid and Factorial Design as Basic Tools
Statistical Optimization of Spray-Dried Extract from Leaves of Croton blanchetianus: Simplex Centroid and Factorial Design as Basic Tools
Studies have reported that Croton blanchetianus Baill., Euphorbiaceae, has anti-inflammatory effects triggered by the pres...
Calcium Channel Blockade Mediates the Tracheal Relaxation of 6,7-Dimethoxycoumarin Isolated from Magnolia mexicana
Calcium Channel Blockade Mediates the Tracheal Relaxation of 6,7-Dimethoxycoumarin Isolated from Magnolia mexicana
Magnolia mexicana DC., Magnoliaceae, is known as “Flor de corazón” or “Yolloxochitl” and is u...
Anti-diabetic Effect of Major Compounds from Commelina diffusa
Anti-diabetic Effect of Major Compounds from Commelina diffusa
Although Commelina diffusa Burm.f., Commelinaceae, has been proven to exhibit many pharmacological activities, the scienti...
Amelioration of Cognitive Deficit by Cryptotanshinone in a Long-term Utilisation of Proton Pump Inhibitor-Induced Alzheimer’s Disease-Like Condition in a Rat Model
Amelioration of Cognitive Deficit by Cryptotanshinone in a Long-term Utilisation of Proton Pump Inhibitor-Induced Alzheimer’s Disease-Like Condition in a Rat Model
Lansoprazole is a proton pump inhibitor, used to treat acid-related diseases, like reflux esophagitis, gastric and duodena...
A Validated HPLC Method for the Simultaneous Quantification of Curcumin, Silybin, and Psoralen: Application to Phytopharmaceuticals
A Validated HPLC Method for the Simultaneous Quantification of Curcumin, Silybin, and Psoralen: Application to Phytopharmaceuticals
The present study was aimed to develop a simple, sensitive, and precise reversed-phase HPLC method for the simultaneous se...
Quinoa and Chia Modulate AMPK/PPAR-ɣ Signaling in High-Fat Diet–Induced Obesity Rat Model
Quinoa and Chia Modulate AMPK/PPAR-ɣ Signaling in High-Fat Diet–Induced Obesity Rat Model
Obesity is one of the principal reasons behind a wide range of metabolic diseases and dramatic health complications. Recen...
Linalool Mitigated High-Fat Diet–Induced Non-alcoholic Fatty Liver Disease by Regulating the Intestinal-Hepatic Axis via TGF-β/NF-kB/TLR4/ZO-1 Pathway
Linalool Mitigated High-Fat Diet–Induced Non-alcoholic Fatty Liver Disease by Regulating the Intestinal-Hepatic Axis via TGF-β/NF-kB/TLR4/ZO-1 Pathway
Non-alcoholic fatty liver disease is a persistent state and frequently accompanied by inflammation and disruption of the e...
Role of Atractylenolide I in Cerebral Ischemia Reperfusion Injury
Role of Atractylenolide I in Cerebral Ischemia Reperfusion Injury
Atractylenolide I is one of the main sesquiterpene lactones of Atractylodes macrocephala Koidz., Asteraceae, and its biolo...
Correction: Tanshinol Inhibits Periodontitis Through IκBα Promotion
Correction: Tanshinol Inhibits Periodontitis Through IκBα Promotion
Department of Stomatology, Ningxia Hui Autonomous Region People’s Hospital, Yinchuan, Ningxia, ChinaLi Liu, Jiaqi Li &...
Mahanimbine Suppresses the Proliferation of Lung Cancer A549 Cells Via Inducing Intrinsic Apoptotic Pathway
Mahanimbine Suppresses the Proliferation of Lung Cancer A549 Cells Via Inducing Intrinsic Apoptotic Pathway
Mahanimbine is a carbazole alkaloid that has been identified and isolated from several members of the Rutaceae family. Pre...
Anti-inflammatory Activity of Total Alkaloids in Nelumbo nucifera and Simultaneous Determination of Major Bisbenzylisoquinolines
Anti-inflammatory Activity of Total Alkaloids in Nelumbo nucifera and Simultaneous Determination of Major Bisbenzylisoquinolines
Plumula nelumbinis, the green embryo of the mature seeds of Nelumbo nucifera Gaertn., Nelumbonaceae, is widely used in tra...
Dehydroandrographolide Improvement of Acetaminophen-Induced Acute Liver Failure
Dehydroandrographolide Improvement of Acetaminophen-Induced Acute Liver Failure
Acetaminophen-induced drug-induced acute liver injury is a liver disease which is one of the most serious human health dis...
Myeloperoxidase Inhibition and In Silico Evaluation of Phenolics from Vellozia dasypus
Myeloperoxidase Inhibition and In Silico Evaluation of Phenolics from Vellozia dasypus
The objective of this study was to investigate the effect on the myeloperoxidase-chlorinating activity in vitro and on neu...
Brazilian Brown Propolis: an Overview About Its Chemical Composition, Botanical Sources, Quality Control, and Pharmacological Properties
Brazilian Brown Propolis: an Overview About Its Chemical Composition, Botanical Sources, Quality Control, and Pharmacological Properties
Brazil is one of the largest propolis producers in the world. Propolis is produced by bees from plant exudates and tissues...
The Anti-angiogenic and Anti-microbial Effect of Diosmin: Potential Receptor Interactions via Molecular Docking
The Anti-angiogenic and Anti-microbial Effect of Diosmin: Potential Receptor Interactions via Molecular Docking
This study examined the antiangiogenic capacity of diosmin in vitro and their interactions with certain important receptor...
Metabolomic Profiling and Cytotoxic Activity of Launaea nudicaulis: Molecular Docking with Topoisomerases
Metabolomic Profiling and Cytotoxic Activity of Launaea nudicaulis: Molecular Docking with Topoisomerases
Launaea nudicaulis (L.) Hook. f., Asteraceae, is a wild plant growing in Egypt, used traditionally for treatment of many d...
Medicinal Plants in Peru as a Source of Immunomodulatory Drugs Potentially Useful Against COVID-19
Medicinal Plants in Peru as a Source of Immunomodulatory Drugs Potentially Useful Against COVID-19
The current COVID-19 pandemic, characterized by a highly contagious severe acute respiratory syndrome, led us to look for ...
Astaxanthin- Enriched Fraction from the Microalga Haematococcus pluvialis Mitigates Kidney Injury via Modulation of Nrf2/Keap1 and MAPK/ERK Pathways in Rats
Astaxanthin- Enriched Fraction from the Microalga Haematococcus pluvialis Mitigates Kidney Injury via Modulation of Nrf2/Keap1 and MAPK/ERK Pathways in Rats
Acute kidney injury is a complication of using gentamicin in high doses and is associated with severe morbidity and mortal...
Quercetin-3-O-rutinoside from Moringa oleifera Downregulates Adipogenesis and Lipid Accumulation and Improves Glucose Uptake by Activation of AMPK/Glut-4 in 3T3-L1 Cells
Quercetin-3-O-rutinoside from Moringa oleifera Downregulates Adipogenesis and Lipid Accumulation and Improves Glucose Uptake by Activation of AMPK/Glut-4 in 3T3-L1 Cells
Natural product-based therapeutic alternatives have drawn immense interest to deal with growing incidence of metabolic dis...
Microbial Transformation of Azorellane and Mulinane Diterpenoids
Microbial Transformation of Azorellane and Mulinane Diterpenoids
Microbial transformation is an alternate strategy to obtain novel derivatives from natural products using whole cells or e...
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