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Phytochemicals in Cancer Therapy: Modulating Cell Cycle, Angiogenesis, and Epithelial-Mesenchymal Transition
Phytochemicals in Cancer Therapy: Modulating Cell Cycle, Angiogenesis, and Epithelial-Mesenchymal Transition
Cancer remains one of the leading causes of death worldwide. Various environmental and lifestyle factors that can be modif...
Reflections and Perspectives on the Caatinga Drylands for the Development of Bioactive Plant Products as Medicine
Reflections and Perspectives on the Caatinga Drylands for the Development of Bioactive Plant Products as Medicine
The Caatinga biome, which is situated in the interior regions of northeastern Brazil, is a well-defined and recognized eco...
Effects of S-allyl Cysteine on Vascular Reactivity in Ovariectomized Rats
Effects of S-allyl Cysteine on Vascular Reactivity in Ovariectomized Rats
Cardiovascular diseases are a major global health issue, particularly among menopausal women who experience hormonal fluct...
Antitrypanosomal Activity of Hydroquinone and Quinone Derivatives Isolated from Miconia willdenowii
Antitrypanosomal Activity of Hydroquinone and Quinone Derivatives Isolated from Miconia willdenowii
Bioactivity-guided fractionation of an anti-Trypanosoma cruzi active extract from Miconia willdenowii Klotzsch ex Naudin, ...
Validation and Quantification of Key Markers in Ayush Kwath, an Ayurvedic Immunity Enhancer Polyherbal Formulation, Through High-Performance Thin-Layer Chromatography
Validation and Quantification of Key Markers in Ayush Kwath, an Ayurvedic Immunity Enhancer Polyherbal Formulation, Through High-Performance Thin-Layer Chromatography
The Indian Ayurvedic formulary certified the polyherbal Ayush kwath preparation, which attracted much interest as a preven...
Evaluation of the Differences of Sour Jujuba Fruits from Diverse Regions Based on the Collaborative Analysis of Organic Acids and Flavor Characters
Evaluation of the Differences of Sour Jujuba Fruits from Diverse Regions Based on the Collaborative Analysis of Organic Acids and Flavor Characters
Sour jujuba (Ziziphus jujuba var. spinosa (Bunge) Hu ex H.F.Chou, Rhamnaceae) is an indigenous plant in northern China, wh...
Toxicity of Uliginosin B in Caenorhabditis elegans Involves P-Glycoprotein and Dopaminergic System
Toxicity of Uliginosin B in Caenorhabditis elegans Involves P-Glycoprotein and Dopaminergic System
Uliginosin B, a dimeric acylphloroglucinol that occurs in several Hypericum species native to South America, has antidepre...
Diethyl Ether Extract of Senna siamea Exhibits Anti-plasmodial Polypharmacology Activity via Modulation of pbEMPI and hepatolipodystrophy Genes
Diethyl Ether Extract of Senna siamea Exhibits Anti-plasmodial Polypharmacology Activity via Modulation of pbEMPI and hepatolipodystrophy Genes
Senna siamea (Lam.) H.S. Irwin & Barneby, Fabaceae, has been used by the locals for the management of malaria over...
Muscone Abates 1,2-Dimethylhydrazine-Induced Colon Cancer in Rats and HCT-116 Cells Proliferation via Modulation of TNF-α, COX-2, NF-kB, and Phase I Xenobiotic Enzymes
Muscone Abates 1,2-Dimethylhydrazine-Induced Colon Cancer in Rats and HCT-116 Cells Proliferation via Modulation of TNF-α, COX-2, NF-kB, and Phase I Xenobiotic Enzymes
Colon cancer ranks third in terms of prevalence and is the second leading cause of cancer-associated deaths globally. Colo...
Flavonol Glycosides from the Leaves of Camellia hirsuta and their α-Glucosidase, α-Amylase, and Advanced Glycation End-Products Inhibitory Effects
Flavonol Glycosides from the Leaves of Camellia hirsuta and their α-Glucosidase, α-Amylase, and Advanced Glycation End-Products Inhibitory Effects
Two new flavonol polysaccharides, named hirsutaosides A (1) and B (2) along with six known compounds were identified as fo...
Embelin Inhibits Dengue Virus Serotype 2 Infectivity with Nonstructural Protein Helicase as a Potential Molecular Target
Embelin Inhibits Dengue Virus Serotype 2 Infectivity with Nonstructural Protein Helicase as a Potential Molecular Target
Dengue is a viral infectious disease which poses a significant threat to global health, affecting approximately 400&nb...
Dictamnine Reduces Gestational Diabetic Complications in Streptozotocin-Induced Diabetic Pregnant Rats via Regulating Inflammation and NOX-2, MCP-1/AGE–RAGE Pathway
Dictamnine Reduces Gestational Diabetic Complications in Streptozotocin-Induced Diabetic Pregnant Rats via Regulating Inflammation and NOX-2, MCP-1/AGE–RAGE Pathway
Gestational diabetes mellitus is a type of diabetes that arises during pregnancy. Around 15–25% of pregnancies are a...
Plant-Derived Nrf2 Activators to Enhance Liver Antioxidative and Regenerative Potentials
Plant-Derived Nrf2 Activators to Enhance Liver Antioxidative and Regenerative Potentials
Excessive reactive oxygen species are harmful to human health due to the spontaneous oxidation of intracellular biomolecul...
Chebulinic Acid Ameliorates Diethylnitrosamine-Induced Hepatocarcinogenesis in Rats by Inhibiting AKT/mTOR Activation and Inhibits Liver Cancer Cell (HepG2) Proliferation
Chebulinic Acid Ameliorates Diethylnitrosamine-Induced Hepatocarcinogenesis in Rats by Inhibiting AKT/mTOR Activation and Inhibits Liver Cancer Cell (HepG2) Proliferation
Hepatocellular carcinoma is an aggressive cancer with a global impact, exacerbated by the increasing rates of metabolic-dy...
Mahanimbine Attenuates Ovariectomy-Induced Osteoporosis in Rats by Regulating Bone Turnover Markers and SIRT1-NF-κB Pathway
Mahanimbine Attenuates Ovariectomy-Induced Osteoporosis in Rats by Regulating Bone Turnover Markers and SIRT1-NF-κB Pathway
Osteoporosis is a significant health problem, characterized by a progressive decline in bone mass and density, which leads...
Photoprotective Effect of Pogonatherum paniceum Extract Against Ultraviolet-B-Induced Skin Aging in HaCaT Keratinocytes
Photoprotective Effect of Pogonatherum paniceum Extract Against Ultraviolet-B-Induced Skin Aging in HaCaT Keratinocytes
UVB radiation causes premature skin aging through generation of reactive oxygen species in skin cells resulting in increas...
Shionone Exhibits Anti-inflammatory and Antiproliferative Effects in Pulmonary Arterial Endothelial Cells and Smooth Muscle Cells via SIRT1 in Pulmonary Arterial Hypertension
Shionone Exhibits Anti-inflammatory and Antiproliferative Effects in Pulmonary Arterial Endothelial Cells and Smooth Muscle Cells via SIRT1 in Pulmonary Arterial Hypertension
Pulmonary arterial hypertension is a progressive disease characterized by pulmonary artery endothelial cell dysfunction, l...
Cell Toxicity of Kadsuric Acid from Kadsura coccinea in Human Pancreatic Cancer Cells Through Caspase/PARP Pathway: In Vitro and In Silico Approach
Cell Toxicity of Kadsuric Acid from Kadsura coccinea in Human Pancreatic Cancer Cells Through Caspase/PARP Pathway: In Vitro and In Silico Approach
Kadsuric acid, a major triterpenoid isolated from the leaves of Vietnamese Kadsura coccinea (Lem.) A.C.Sm., Schisandraceae...
Evaluation of the Antibacterial Potency of Phytochemicals and Their Effects on Host Xenobiotic Response Using Caenorhabditis elegans
Evaluation of the Antibacterial Potency of Phytochemicals and Their Effects on Host Xenobiotic Response Using Caenorhabditis elegans
Antimicrobial resistance poses a huge challenge to the healthcare system, prompting the need to develop new remedies to fi...
Mapping Cutaneous Tissue Distribution of Sesquiterpene Lactone Goyazensolide Using MALDI Imaging
Mapping Cutaneous Tissue Distribution of Sesquiterpene Lactone Goyazensolide Using MALDI Imaging
Species of Lychnophora, popularly known in Brazil as “arnica-da-serra,” are widely used in topical preparation...
Correction: Effect of Cinnamon and Aconite on Bone Formation-Bone Absorption Coupling in Bone Microenvironment
Correction: Effect of Cinnamon and Aconite on Bone Formation-Bone Absorption Coupling in Bone Microenvironment
Cite this articleYao, L., Zhang, Q., Sun, P. et al. Correction: Effect of Cinnamon and Aconite on Bone Formation-Bone Abso...
Anti-cancer Potential of Farrerol Against Esophageal Carcinoma via Inhibiting STAT3-EGFR Signaling Pathway
Anti-cancer Potential of Farrerol Against Esophageal Carcinoma via Inhibiting STAT3-EGFR Signaling Pathway
The objective of this study was to examine the cytotoxic effects of farrerol on esophageal cancer cells. Firstly, the infl...
Artemisia afra and COVID-19, the Media Storm Versus the Current State-of-the-Art
Artemisia afra and COVID-19, the Media Storm Versus the Current State-of-the-Art
During the COVID-19 pandemic, the traditional herbal medicine Artemisia afra Jacq. ex Willd., Asteraceae, was widely used ...
Oral Mucosa and Subacute Systemic Toxicity of Anacardic Acids‑Loaded Zein Nanoparticles
Oral Mucosa and Subacute Systemic Toxicity of Anacardic Acids‑Loaded Zein Nanoparticles
Anacardic acid, a bioactive chemical from the cashew shell liquid of Anacardium occidentale L., Anacardiaceae, is a promis...
The Effect of Natural Plant Products in the Management of Autoimmune Diseases Along with Photodynamic Therapy
The Effect of Natural Plant Products in the Management of Autoimmune Diseases Along with Photodynamic Therapy
Due to the high prevalence and inefficiency of the already existing treatment of autoimmune diseases, researchers are inve...
Neuroprotective Effects of Hippeastrum elegans Extract: Anticholinesterase Effect In Silico and In Vivo Studies in the Scopolamine-Induced Memory Deficits Model in Rat
Neuroprotective Effects of Hippeastrum elegans Extract: Anticholinesterase Effect In Silico and In Vivo Studies in the Scopolamine-Induced Memory Deficits Model in Rat
Alzheimer’s disease is a chronic and progressive neurodegenerative disease that causes severe cognitive decline and ...
Cyclosporin A Enhance the Cytotoxicity of Immunotoxin to the HER-2-Overexpressing SK-OV-3 Cells: A Prospective Study
Cyclosporin A Enhance the Cytotoxicity of Immunotoxin to the HER-2-Overexpressing SK-OV-3 Cells: A Prospective Study
This study explores the synergistic effect of T-CUS245C combined with cyclosporin A, and its possible mechanism. T-CUS245C...
Inhibitors of Nitric Oxide Production from the Seeds of Myristica fragrans: Experimental and Computational Results
Inhibitors of Nitric Oxide Production from the Seeds of Myristica fragrans: Experimental and Computational Results
This study focuses on the extraction of eleven compounds from Myristica fragrans Houtt., Miristicaceae, seeds, guided by t...
In Vivo Study to Explore the Antiarthritic Potential of Tiliroside on Complete Freund’s Adjuvant-Induced Rheumatoid Arthritis in Rats
In Vivo Study to Explore the Antiarthritic Potential of Tiliroside on Complete Freund’s Adjuvant-Induced Rheumatoid Arthritis in Rats
The purpose of this research was to examine the pharmacological properties and potential mechanism of action of tiliroside...
Inhibition of Human CYP1A1/A2 by a Hydroalcoholic Extract and Its Neolignan Constituents from Piper rivinoides
Inhibition of Human CYP1A1/A2 by a Hydroalcoholic Extract and Its Neolignan Constituents from Piper rivinoides
Lignans and neolignans, commonly found in plants, are generally composed of two phenylpropane (C6-C3) units with a marked ...
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