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Dictamnine Reduces Gestational Diabetic Complications in Streptozotocin-Induced Diabetic Pregnant Rats via Regulating Inflammation and NOX-2, MCP-1/AGE–RAGE Pathway
Dictamnine Reduces Gestational Diabetic Complications in Streptozotocin-Induced Diabetic Pregnant Rats via Regulating Inflammation and NOX-2, MCP-1/AGE–RAGE Pathway
Gestational diabetes mellitus is a type of diabetes that arises during pregnancy. Around 15–25% of pregnancies are a...
Plant-Derived Nrf2 Activators to Enhance Liver Antioxidative and Regenerative Potentials
Plant-Derived Nrf2 Activators to Enhance Liver Antioxidative and Regenerative Potentials
Excessive reactive oxygen species are harmful to human health due to the spontaneous oxidation of intracellular biomolecul...
Chebulinic Acid Ameliorates Diethylnitrosamine-Induced Hepatocarcinogenesis in Rats by Inhibiting AKT/mTOR Activation and Inhibits Liver Cancer Cell (HepG2) Proliferation
Chebulinic Acid Ameliorates Diethylnitrosamine-Induced Hepatocarcinogenesis in Rats by Inhibiting AKT/mTOR Activation and Inhibits Liver Cancer Cell (HepG2) Proliferation
Hepatocellular carcinoma is an aggressive cancer with a global impact, exacerbated by the increasing rates of metabolic-dy...
Mahanimbine Attenuates Ovariectomy-Induced Osteoporosis in Rats by Regulating Bone Turnover Markers and SIRT1-NF-κB Pathway
Mahanimbine Attenuates Ovariectomy-Induced Osteoporosis in Rats by Regulating Bone Turnover Markers and SIRT1-NF-κB Pathway
Osteoporosis is a significant health problem, characterized by a progressive decline in bone mass and density, which leads...
Photoprotective Effect of Pogonatherum paniceum Extract Against Ultraviolet-B-Induced Skin Aging in HaCaT Keratinocytes
Photoprotective Effect of Pogonatherum paniceum Extract Against Ultraviolet-B-Induced Skin Aging in HaCaT Keratinocytes
UVB radiation causes premature skin aging through generation of reactive oxygen species in skin cells resulting in increas...
Shionone Exhibits Anti-inflammatory and Antiproliferative Effects in Pulmonary Arterial Endothelial Cells and Smooth Muscle Cells via SIRT1 in Pulmonary Arterial Hypertension
Shionone Exhibits Anti-inflammatory and Antiproliferative Effects in Pulmonary Arterial Endothelial Cells and Smooth Muscle Cells via SIRT1 in Pulmonary Arterial Hypertension
Pulmonary arterial hypertension is a progressive disease characterized by pulmonary artery endothelial cell dysfunction, l...
Cell Toxicity of Kadsuric Acid from Kadsura coccinea in Human Pancreatic Cancer Cells Through Caspase/PARP Pathway: In Vitro and In Silico Approach
Cell Toxicity of Kadsuric Acid from Kadsura coccinea in Human Pancreatic Cancer Cells Through Caspase/PARP Pathway: In Vitro and In Silico Approach
Kadsuric acid, a major triterpenoid isolated from the leaves of Vietnamese Kadsura coccinea (Lem.) A.C.Sm., Schisandraceae...
Evaluation of the Antibacterial Potency of Phytochemicals and Their Effects on Host Xenobiotic Response Using Caenorhabditis elegans
Evaluation of the Antibacterial Potency of Phytochemicals and Their Effects on Host Xenobiotic Response Using Caenorhabditis elegans
Antimicrobial resistance poses a huge challenge to the healthcare system, prompting the need to develop new remedies to fi...
Mapping Cutaneous Tissue Distribution of Sesquiterpene Lactone Goyazensolide Using MALDI Imaging
Mapping Cutaneous Tissue Distribution of Sesquiterpene Lactone Goyazensolide Using MALDI Imaging
Species of Lychnophora, popularly known in Brazil as “arnica-da-serra,” are widely used in topical preparation...
Correction: Effect of Cinnamon and Aconite on Bone Formation-Bone Absorption Coupling in Bone Microenvironment
Correction: Effect of Cinnamon and Aconite on Bone Formation-Bone Absorption Coupling in Bone Microenvironment
Cite this articleYao, L., Zhang, Q., Sun, P. et al. Correction: Effect of Cinnamon and Aconite on Bone Formation-Bone Abso...
Anti-cancer Potential of Farrerol Against Esophageal Carcinoma via Inhibiting STAT3-EGFR Signaling Pathway
Anti-cancer Potential of Farrerol Against Esophageal Carcinoma via Inhibiting STAT3-EGFR Signaling Pathway
The objective of this study was to examine the cytotoxic effects of farrerol on esophageal cancer cells. Firstly, the infl...
Artemisia afra and COVID-19, the Media Storm Versus the Current State-of-the-Art
Artemisia afra and COVID-19, the Media Storm Versus the Current State-of-the-Art
During the COVID-19 pandemic, the traditional herbal medicine Artemisia afra Jacq. ex Willd., Asteraceae, was widely used ...
Oral Mucosa and Subacute Systemic Toxicity of Anacardic Acids‑Loaded Zein Nanoparticles
Oral Mucosa and Subacute Systemic Toxicity of Anacardic Acids‑Loaded Zein Nanoparticles
Anacardic acid, a bioactive chemical from the cashew shell liquid of Anacardium occidentale L., Anacardiaceae, is a promis...
The Effect of Natural Plant Products in the Management of Autoimmune Diseases Along with Photodynamic Therapy
The Effect of Natural Plant Products in the Management of Autoimmune Diseases Along with Photodynamic Therapy
Due to the high prevalence and inefficiency of the already existing treatment of autoimmune diseases, researchers are inve...
Neuroprotective Effects of Hippeastrum elegans Extract: Anticholinesterase Effect In Silico and In Vivo Studies in the Scopolamine-Induced Memory Deficits Model in Rat
Neuroprotective Effects of Hippeastrum elegans Extract: Anticholinesterase Effect In Silico and In Vivo Studies in the Scopolamine-Induced Memory Deficits Model in Rat
Alzheimer’s disease is a chronic and progressive neurodegenerative disease that causes severe cognitive decline and ...
Cyclosporin A Enhance the Cytotoxicity of Immunotoxin to the HER-2-Overexpressing SK-OV-3 Cells: A Prospective Study
Cyclosporin A Enhance the Cytotoxicity of Immunotoxin to the HER-2-Overexpressing SK-OV-3 Cells: A Prospective Study
This study explores the synergistic effect of T-CUS245C combined with cyclosporin A, and its possible mechanism. T-CUS245C...
Inhibitors of Nitric Oxide Production from the Seeds of Myristica fragrans: Experimental and Computational Results
Inhibitors of Nitric Oxide Production from the Seeds of Myristica fragrans: Experimental and Computational Results
This study focuses on the extraction of eleven compounds from Myristica fragrans Houtt., Miristicaceae, seeds, guided by t...
In Vivo Study to Explore the Antiarthritic Potential of Tiliroside on Complete Freund’s Adjuvant-Induced Rheumatoid Arthritis in Rats
In Vivo Study to Explore the Antiarthritic Potential of Tiliroside on Complete Freund’s Adjuvant-Induced Rheumatoid Arthritis in Rats
The purpose of this research was to examine the pharmacological properties and potential mechanism of action of tiliroside...
Inhibition of Human CYP1A1/A2 by a Hydroalcoholic Extract and Its Neolignan Constituents from Piper rivinoides
Inhibition of Human CYP1A1/A2 by a Hydroalcoholic Extract and Its Neolignan Constituents from Piper rivinoides
Lignans and neolignans, commonly found in plants, are generally composed of two phenylpropane (C6-C3) units with a marked ...
Effects of Spermidine Macrocyclic Alkaloids on the Expression of Amyloid β-Peptide in SH-SY5Y Cells via Autophagy
Effects of Spermidine Macrocyclic Alkaloids on the Expression of Amyloid β-Peptide in SH-SY5Y Cells via Autophagy
Three macrocyclic polyamine alkaloids with a 13-membered ring, named celafurine, celacarfurine, and celabenzine, isolated ...
Caudatin Inhibits Cell Proliferation and Migration Via Apoptosis in Human Hepatocellular Carcinoma Cells
Caudatin Inhibits Cell Proliferation and Migration Via Apoptosis in Human Hepatocellular Carcinoma Cells
The aim of this study was to investigate the impact of caudatin on the biological function of hepatocellular carcinoma cel...
Flavonoids from Rhodiola fastigiata and their Antimalarial Activities
Flavonoids from Rhodiola fastigiata and their Antimalarial Activities
A new flavonoid glycoside, herbacetin-8-O-methyl glucuronide, together with nine known flavonoids herbacetin-8-O-β-d-...
Medicinal Plants and Their Constituents with Estrogenic Activity
Medicinal Plants and Their Constituents with Estrogenic Activity
Phytoestrogenic plants are found to serve as a secure substitute for hormone replacement therapy practiced at present to t...
Icariside II Suppresses the Malignant Behaviors of Breast Cancer Cells by Inhibiting PTGES3 Expression
Icariside II Suppresses the Malignant Behaviors of Breast Cancer Cells by Inhibiting PTGES3 Expression
Here, we aimed to explore the roles of prostaglandin E synthase 3 in breast cancer and assess whether icariside II inhibit...
Xanthine Oxidase Inhibitory Activity and Uric Acid Dissolution Power of Some Plant Extracts: In Vitro Therapeutical Approach for Gout Treatment
Xanthine Oxidase Inhibitory Activity and Uric Acid Dissolution Power of Some Plant Extracts: In Vitro Therapeutical Approach for Gout Treatment
Elevated serum levels of uric acid are associated with an increased risk of hyperuricemia and gout. Recent attention has f...
Volatile Oil from Piper macedoi: A New Perspective for Aedes aegypti Mosquito Control
Volatile Oil from Piper macedoi: A New Perspective for Aedes aegypti Mosquito Control
In 2024, Brazil and the rest of Latin America are confronting a significant challenge related to dengue fever. The vector ...
Shionone Relieves LPS-Induced Acute Lung Injury by Regulating the TNIP2/NF-kB Pathway
Shionone Relieves LPS-Induced Acute Lung Injury by Regulating the TNIP2/NF-kB Pathway
Acute lung injury, a diffuse inflammatory injury caused by various factors, is characterized by respiratory distress and p...
Insights into the Composition of Breu Canauaru, an Enigmatic Medicinal “Resin” from Amazonia
Insights into the Composition of Breu Canauaru, an Enigmatic Medicinal “Resin” from Amazonia
Breu canauaru is well-known in the Brazilian Amazon for its purported medicinal and magical properties, but its origin has...
Baicalein: Multiple Pharmacological Activities, Pharmacokinetics, and Clinical Trials
Baicalein: Multiple Pharmacological Activities, Pharmacokinetics, and Clinical Trials
Baicalein, a flavone present in various plants, has gained widespread recognition for its variety of health benefits. It e...
Detecting Phytoestrogens and Mammalian Estrogens in Blackcurrants (Ribes nigrum)
Detecting Phytoestrogens and Mammalian Estrogens in Blackcurrants (Ribes nigrum)
Phytoestrogens are estrogen-like compounds found in various plants. Menopausal women experience various menopausal symptom...
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