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Structure-guided metagenome mining to tap microbial functional diversity
Structure-guided metagenome mining to tap microbial functional diversity
Scientists now have access to millions of accurate three-dimensional (3D) models of protein structures. How do we leverage...
The skin mycobiome and intermicrobial interactions in the cutaneous niche
The skin mycobiome and intermicrobial interactions in the cutaneous niche
Mammalian microbiomes have coevolved with their host to establish a stable homeostatic relationship. Multifaceted commensa...
Design of synthetic bacterial biosensors
Design of synthetic bacterial biosensors
Novel whole-cell bacterial biosensor designs require an emphasis on moving toward field deployment. Many current sensors a...
Interkingdom interactions between Pseudomonas aeruginosa and Candida albicans affect clinical outcomes and antimicrobial responses
Interkingdom interactions between Pseudomonas aeruginosa and Candida albicans affect clinical outcomes and antimicrobial responses
Infections that involve interkingdom microbial communities, such as those between bacteria and yeast pathogens, are diffic...
Bacteriophage communities are a reservoir of unexplored microbial diversity in neonatal health and disease
Bacteriophage communities are a reservoir of unexplored microbial diversity in neonatal health and disease
Acquisition and development of the gut microbiome are vital for immune education in neonates, especially those born preter...
Editorial overview: Turtles all the way down: Bacterial cell regulation across scales
Editorial overview: Turtles all the way down: Bacterial cell regulation across scales
Peter Chien studies molecular mechanisms of stress responses and protein turnover motivated by bacterial systems. He was t...
Conditionally unutilized proteins and their profound effects on growth and adaptation across microbial species
Conditionally unutilized proteins and their profound effects on growth and adaptation across microbial species
Protein synthesis is an important determinant of microbial growth and response that demands a high amount of metabolic and...
Bacterial acid stress response: from cellular changes to antibiotic tolerance and phenotypic heterogeneity
Bacterial acid stress response: from cellular changes to antibiotic tolerance and phenotypic heterogeneity
Most bacteria are neutralophiles but can survive fluctuations in pH in their environment. Herein, we provide an overview o...
Fungal pathogens and COVID-19
Fungal pathogens and COVID-19
COVID-19 pandemic highlighted the complications of secondary fungal infections that occurred globally in severe cases of c...
An update on the current understanding of the infant skin microbiome and research challenges
An update on the current understanding of the infant skin microbiome and research challenges
Multiple factors contribute to establishment of skin microbial communities in early life, with perturbations in these ecos...
Modelling of microbial interactions in anaerobic digestion: from black to glass box
Anaerobic and microaerophilic environments are pervasive in nature, providing essential contributions to the maintenance o...
Human intestinal organoids as models to study enteric bacteria and viruses
Laboratory studies of host–microbe interactions have historically been carried out using transformed cell lines and animal...
The mycobiome: interactions with host and implications in diseases
Over the past decade, our understanding of the composition and function of the human mucosal surface-associated fungal com...
Interplay of emerging and established technologies drives innovation in natural product antibiotic discovery
A continued rise of antibiotic resistance and shortages of effective antibiotics necessitate the discovery and development...
Recent advances in the development of metal complexes as antibacterial agents with metal-specific modes of action
The mounting burden of antimicrobial resistance (AMR) is one of the most concerning threats to public health worldwide. Wi...
Editorial overview: Recent advances in fundamental and translational research on parasitic protists
Christian Doerig obtained a degree in science education and a Ph.D. in molecular virology at the University of Lausanne, S...
Accessing nutrients as the primary benefit arising from chemotaxis
About half of the known bacterial species perform chemotaxis that gains them access to sites that are optimal for growth a...
Microbial interactions in theory and practice: when are measurements compatible with models?
Most predictive models of ecosystem dynamics are based on interactions between organisms: their influence on each other’s ...
Editorial overview: Unraveling microbiome complexity
Dr Jacob Malone is an expert in bacterial signaling and behavior during host interactions. He has been a group leader in t...
Lessons from arbuscular mycorrhizal fungal genomes
Arbuscular mycorrhizal fungi (AMF) have accompanied the majority of land plants since their evolution in the Devonian peri...
Emergent CRISPR–Cas-based technologies for engineering non-model bacteria
Clustered regularly interspaced short palindromic repeats (CRISPR)–CRISPR-associated proteins (Cas) technologies brought a...
The promise of copper ionophores as antimicrobials
Antibiotic-resistant microbe-mediated deaths are a major worldwide health issue. Unfortunately, due to microbial adaptatio...
Editorial overview: Evolution of antiviral defense
Philip Kranzusch is a professor of microbiology at Harvard Medical School and the Dana-Farber Cancer Institute. His resear...
Roles of Hsp90 in Candida albicans morphogenesis and virulence
Hsp90 is a conserved molecular chaperone that facilitates the folding and function of hundreds of client proteins, many of...
Soterobionts: disease-preventing microorganisms and proposed strategies to facilitate their discovery
Crop production and the food security that it provides are currently threatened worldwide by plant pathogens. Conventional...
Nothing makes sense in drug resistance except in the light of evolution
Our ability to fight infectious diseases is being increasingly compromised due to the emergence and spread of pathogens th...
Synthesizing microbial biodiversity
The diversity of microbial ecosystems is linked to crucial ecological processes and functions. Despite its significance, t...
Continued mycovirus discovery expanding our understanding of virus lifestyles, symptom expression, and host defense
High-throughput sequencing technologies have greatly expanded the RNA virome in general and have led to an exponential inc...
Counteracting antibiotic resistance enzymes and efflux pumps
Bacterial pathogens are constantly evolving new resistance mechanisms against antibiotics; hence, strategies to potentiate...
Fungus–insect interactions beyond bilateral regimes: the importance and strategy to outcompete host ectomicrobiomes by fungal parasites
Fungus–insect interactions have long been investigated at the bilateral level to unveil the factors involved in mediating ...
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