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Toxin–antitoxin systems as mediators of phage defence and the implications for abortive infection
Bacteria have evolved a broad range of defence mechanisms to protect against infection by their viral parasites, bacteriop...
Moving beyond DNA: towards functional analysis of the vaginal microbiome by non-sequencing-based methods
Over the last two decades, sequencing-based methods have revolutionised our understanding of niche-specific microbial comp...
Reservoirs of antimicrobial resistance in the context of One Health
The emergence and spread of antimicrobial resistance (AMR) and resistant bacteria, are a global public health challenge. T...
Bioremediation of the herbicide glyphosate in polluted soils by plant-associated microbes
Most productive lands worldwide base their crop production on the use of glyphosate (GLY)-resistant plants, and consequent...
The use of evolutionary analyses to predict functionally relevant traits in filamentous plant pathogens
Volume 73, June 2023, 102244Author links open overlay panel, Highlights•Plant pathogens specialise to the infection of dis...
Human microbiome variance is underestimated
Most of the variance in the human microbiome remains unexplained. Although an extensive list of individual lifestyles shap...
Microbes to support plant health: understanding bioinoculant success in complex conditions
A promising, sustainable way to enhance plant health and productivity is by leveraging beneficial microbes. Beneficial mic...
CTP switches in ParABS-mediated bacterial chromosome segregation and beyond
Segregation of genetic material is a fundamental process in biology. In many bacterial species, segregation of chromosomes...
Plant pathogens and symbionts target the plant nucleus
In plant–microbe interactions, symbionts and pathogens live within plants and attempt to avoid triggering plant defense re...
“What I cannot create, I do not understand": elucidating microbe–microbe interactions to facilitate plant microbiome engineering
Plant–microbe interactions are important for both physiological and pathological processes. Despite the significance of pl...
Impact of caloric restriction on the gut microbiota
Caloric restriction (CR) and related time-restricted diets have been popularized as means of preventing metabolic disease ...
How do interactions between mobile genetic elements affect horizontal gene transfer?
Horizontal gene transfer is central to bacterial adaptation and is facilitated by mobile genetic elements (MGEs). Increasi...
Ready, STAT3, Go! Bacteria in the race for M2 macrophage polarisation
Despite macrophages representing professional immune cells that are integral to the host defences against microbial threat...
The evolutionary ecology of rhizobia: multiple facets of competition before, during, and after symbiosis with legumes
Rhizobial bacteria have complex lifestyles that involve growth and survival in bulk soil, plant rhizospheres and rhizoplan...
Activation of complement-like antiparasitic responses in Anopheles mosquitoes
During their development in mosquitoes, malaria parasites undergo massive losses that are in part due to a potent antipara...
Regulation of peptidoglycan hydrolases: localization, abundance, and activity
Most bacteria are surrounded by a cell wall composed of peptidoglycan (PG) that specifies shape and protects the cell from...
Capers with caspases: Toxoplasma gondii tales of inflammation and survival
Intracellular pathogens strike a delicate balance between maintaining their survival within infected cells, while also act...
Editorial overview: Return of the phages — a new golden era of molecular discovery and synthetic biology
Martin J Loessner is full professor of microbiology at the Institute of Food, Nutrition & Health, Federal Institute of...
Spatiotemporal perspectives on tuberculosis chemotherapy
Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis (TB), accounts for over ten million infections and o...
Ca2+-calmodulin signalling at the host-pathogen interface
Multiple eukaryotic cell processes are modulated by calcium ions (Ca2+). As such, Ca2+ is emerging as a crucial regulator ...
Host genetics regulate the plant microbiome
Plants recruit a taxonomically diverse microbial community, collectively termed the plant microbiome, that includes mutual...
Chemical communication in plant–microbe beneficial interactions: a toolbox for precise management of beneficial microbes
Harnessing the power of beneficial microbes in the rhizosphere to improve crop performance is a key goal of sustainable ag...
Microbiome rescue: directing resilience of environmental microbial communities
Earth’s climate crisis threatens to disrupt ecosystem services and destabilize food security. Microbiome management will b...
One species, different diseases: the unique molecular mechanisms that underlie the pathogenesis of typhoidal Salmonella infections
Salmonella enterica is one of the most widespread bacterial pathogens found worldwide, resulting in approximately 100 mill...
Gaps in the wall: understanding cell wall biology to tackle amoxicillin resistance in Streptococcus pneumoniae
Streptococcus pneumoniae is the most common cause of community-acquired pneumonia, and one of the main pathogens responsib...
Within-host evolution of the gut microbiome
Gut bacteria inhabit a complex environment that is shaped by interactions with their host and the other members of the com...
Reframing antimicrobial resistance as a continuous spectrum of manifestations
To fight antimicrobial resistance (AMR), we must recognize and target all its manifestations. In this review, we briefly s...
Yersinia interactions with regulated cell death pathways
Cell death in response to infection is conserved across all kingdoms of life. In metazoans, cell death upon bacterial infe...
Host control by SPβ phage regulatory switch as potential manipulation strategy
The interaction between temperate phages and their bacterial hosts has always been one of the most controversial in nature...
Streptomyces behavior and competition in the natural environment
Streptomyces are ubiquitous terrestrial bacteria that are renowned for their robust metabolic capabilities and their behav...