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New sesquiterpenes and viridin derivatives from Penicillium sp. Ameliorates NAFLD by regulating the PINK1/Parkin mitophagy pathway
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Synthesis and biological evaluation of novel isoxazoloquinone derivatives as potent STAT3-targeting antipsoriasis agents
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New polycyclic polyprenylated acylphloroglucinols with antidepressant activities from Hypericum perforatum L.
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Development and biological evaluation of 68Ga-labeled peptides for potential application in HER2-positive colorectal cancer
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7-Amino-[1,2,4]triazolo[1,5-a][1,3,5]triazines as CK1δ inhibitors: Exploring substitutions at the 2 and 5-positions
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Auto-induction, biochemical characterization and application of a novel thermo-alkaline and detergent-stable lipase (S9 peptidase domain) from Thermotoga petrophila as cleaning additive and degrading oil/fat wastes
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TRIP13 − a potential drug target in cancer pharmacotherapy
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Synthesis and broad-spectrum biocidal effect of novel gemini quaternary ammonium compounds
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Design, synthesis and anticancer activity of β-carboline based pseudo-natural products by inhibiting AKT/mTOR signaling pathway
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Activity-based protein profiling in drug/pesticide discovery: Recent advances in target identification of antibacterial compounds
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Novel mandelic acid derivatives containing piperazinyls as potential candidate fungicides against Monilinia fructicola: Design, synthesis and mechanism study
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Intriguing steroid glycosides for cancer therapy by suppressing the DNA damage response and mTOR/S6K signaling pathways
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A novel approach to investigate the combinatorial effects of TLK1 (Tousled-Like Kinase1) inhibitors with Temozolomide for glioblastoma therapy
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Targeting DNA methyltransferases for cancer therapy
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Synthetic routes and clinical application of Small-Molecule HER2 inhibitors for cancer therapy
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Critical review on plant-derived quorum sensing signaling inhibitors in pseudomonas aeruginosa
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Cephalostatins and ritterazines: Distinctive dimeric marine-derived steroidal pyrazine alkaloids with intriguing anticancer activities
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Design of Multi-Target drugs of HDACs and other Anti-Alzheimer related Targets: Current strategies and future prospects in Alzheimer’s diseases therapy
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Corrigendum to “Sulfonamides as anticancer agents: A brief review on sulfonamide derivatives as inhibitors of various proteins overexpressed in cancer” [Bioorg. Chem. 147 (2024) 107409]
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Corrigendum to “Discovery of KRas G12C-IN-3 and Pomalidomide-based PROTACs as degraders of endogenous KRAS G12C with potent anticancer activity” [Bioorgan. Chem. 117 (2021) 105447]
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Unveiling the potential of isatin-grafted phenyl-1,2,3-triazole derivatives as dual VEGFR-2/STAT-3 inhibitors: Design, synthesis and biological assessments
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Investigating the effect of ligand structure on the anticancer properties of several new Co(II) complexes of vitaminB3-based phosphoramides
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Discovery and evolution of berberine analogues as anti-Helicobacter pylori agents with multi-target mechanisms
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Haperforatones A-M, thirteen undescribed limonoids from Harrisonia perforata with anti-inflammatory activity
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Macrocyclic peptides derived from AcPHF6* and AcPHF6 to selectively modulate the Tau aggregation
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Novel PROTAC probes targeting FOSL1 degradation to eliminate head and neck squamous cell carcinoma cancer stem cells
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Design and bio-evaluation of novel millepachine derivatives targeting tubulin colchicine binding site for treatment of osteosarcoma
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Synthesis and antimicrobial activity testing of quaternary ammonium silane compounds
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Design and evaluation of novel inhibitors for the treatment of clear cell renal cell carcinoma
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Design and synthesis of 6,20-epoxy A-ring modified oridonin derivatives with antitumor activity through extrinsic and mitochondrial pathways
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