SCI时时刷

search
Acute Kidney Injury and Diastolic Dysfunction: Opportunity for Targeted Intervention?
Acute Kidney Injury and Diastolic Dysfunction: Opportunity for Targeted Intervention?
<b><i>Background/Aims:</i></b> Acute kidney injury (AKI) is common, results in nonrenal sequelae, ...
Myeloid Response to Acute Kidney Injury
Myeloid Response to Acute Kidney Injury
<b><i>Background:</i></b> Myeloid cells form an important element of the response to ischemia-repe...
Targeting Endoplasmic Reticulum for Novel Therapeutics and Monitoring in Acute Kidney Injury
Targeting Endoplasmic Reticulum for Novel Therapeutics and Monitoring in Acute Kidney Injury
<b><i>Background:</i></b> Endoplasmic reticulum (ER) stress response is a conservative mechanism i...
Megalin-Mediated Endocytosis in the Kidney Proximal Tubule: Relevance to Regulation of the Renal Renin-Angiotensin System
Megalin-Mediated Endocytosis in the Kidney Proximal Tubule: Relevance to Regulation of the Renal Renin-Angiotensin System
The kidney proximal tubule is a major target tissue of the renin-angiotensin system (RAS). Megalin is an endocytic multili...
Lessons from Four Decades of Systemic Amyloidosis with Renal Involvement
Lessons from Four Decades of Systemic Amyloidosis with Renal Involvement
<b><i>Background:</i></b> Apart from ATTR amyloidosis, the epidemiology and outcomes of the most c...
Drug-Induced Acute Kidney Injury Risk Prediction Models
Drug-Induced Acute Kidney Injury Risk Prediction Models
<b><i>Background:</i></b> Acute kidney injury (AKI) risk prediction models can predict AKI with sh...
Intravenous Tranexamic Acid in Percutaneous Kidney Biopsy: A Randomized Controlled Trial
Intravenous Tranexamic Acid in Percutaneous Kidney Biopsy: A Randomized Controlled Trial
<b><i>Background:</i></b> Tranexamic acid is frequently reported to reduce bleeding-related compli...
Creatine Kinase Elevation in Autosomal Dominant Polycystic Kidney Disease Patients on Tolvaptan Treatment
Creatine Kinase Elevation in Autosomal Dominant Polycystic Kidney Disease Patients on Tolvaptan Treatment
<b><i>Background:</i></b> Autosomal dominant polycystic kidney disease (ADPKD) is the most common ...
Reprogramming of Energy Metabolism in Kidney Disease
Reprogramming of Energy Metabolism in Kidney Disease
Kidney tubules have high metabolic activity to support solute transport and other cellular functions. Energy generation in...
Regulation of Distal Nephron Transport by Intracellular Chloride and Potassium
Regulation of Distal Nephron Transport by Intracellular Chloride and Potassium
<b><i>Background:</i></b> Low potassium increases the phosphorylation and activity of the sodium c...
The Pathophysiology of Left Ventricular Hypertrophy, beyond Hypertension, in Autosomal Dominant Polycystic Kidney Disease
The Pathophysiology of Left Ventricular Hypertrophy, beyond Hypertension, in Autosomal Dominant Polycystic Kidney Disease
Heart disease is one of the leading causes of death in autosomal dominant polycystic kidney disease (ADPKD) patients. Left...
Heterozygous Variants in a Patient with Karyomegalic Interstitial Nephritis
Heterozygous Variants in a Patient with Karyomegalic Interstitial Nephritis
Karyomegalic interstitial nephritis (KIN) is a rare kidney disease marked by large tubular nuclei, interstitial inflammati...
Humoral Response to the Third Dose of BNT162b2 COVID-19 Vaccine among Hemodialysis Patients
Humoral Response to the Third Dose of BNT162b2 COVID-19 Vaccine among Hemodialysis Patients
<b><i>Background:</i></b> Hemodialysis patients are at high risk for severe COVID-19 disease. Desp...
Soluble (Pro)Renin Receptor in Hypertension
Soluble (Pro)Renin Receptor in Hypertension
The (pro)renin receptor (PRR) was originally cloned as a specific single-transmembrane receptor for prorenin and renin and...
DPP4 Inhibitor-Induced Bullous Pemphigoid in Patients with Diabetes and Chronic Kidney Disease: Clinical Case Series
DPP4 Inhibitor-Induced Bullous Pemphigoid in Patients with Diabetes and Chronic Kidney Disease: Clinical Case Series
<b><i>Introduction:</i></b> Dipeptidyl peptidase-4 (DPP4) inhibitors (gliptins) are commonly presc...
ANCA-Associated Vasculitis following the First Dose of Pfizer-BioNTech COVID-19 Vaccine
ANCA-Associated Vasculitis following the First Dose of Pfizer-BioNTech COVID-19 Vaccine
Coronavirus disease (COVID-19) vaccine can alter the body’s immunological balance leading to autoimmune disease in rare ca...
Federated Learning in Risk Prediction: A Primer and Application to COVID-19-Associated Acute Kidney Injury
Federated Learning in Risk Prediction: A Primer and Application to COVID-19-Associated Acute Kidney Injury
<b><i>Background:</i></b> Modern machine learning and deep learning algorithms require large amoun...
Facing the Challenge of Drug-Induced Acute Interstitial Nephritis
Facing the Challenge of Drug-Induced Acute Interstitial Nephritis
<b><i>Background:</i></b> Acute interstitial nephritis (AIN) is one of the chief causes of acute k...
Acute Changes in Serum Creatinine Are Not a Meaningful Metric in Randomized Controlled Trials and Clinical Care
Acute Changes in Serum Creatinine Are Not a Meaningful Metric in Randomized Controlled Trials and Clinical Care
<b><i>Background:</i></b> Acute changes in serum creatinine are labeled clinically as acute kidney...
miR-181a Improved Renal Inflammation by Targeting TNF-α in a Diabetic Nephropathy Animal Model
miR-181a Improved Renal Inflammation by Targeting TNF-α in a Diabetic Nephropathy Animal Model
<b><i>Introduction:</i></b> Recent studies have elucidated that miR-181a plays a vital role in var...
PAX2/Renal Coloboma Syndrome Expresses Extreme Intrafamilial Phenotypic Variability
PAX2/Renal Coloboma Syndrome Expresses Extreme Intrafamilial Phenotypic Variability
Renal coloboma syndrome (RCS) is a disease characterized by kidney and ocular anomalies (kidney hypodysplasia and coloboma...
Endotoxemic Shock: A Molecular Phenotype in Sepsis
Endotoxemic Shock: A Molecular Phenotype in Sepsis
<b><i>Background:</i></b> Marked heterogeneity exists among patients with sepsis, both in terms of...
Modeling Cisplatin-Induced Kidney Injury to Increase Translational Potential
Modeling Cisplatin-Induced Kidney Injury to Increase Translational Potential
<b><i>Background:</i></b> Cisplatin-induced kidney injury is a major challenge hindering treatment...