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Spondyloarthritis and Sarcopenia: Prevalence of Probable Sarcopenia and its Impact on Disease Burden: The Saspar Study
Spondyloarthritis and Sarcopenia: Prevalence of Probable Sarcopenia and its Impact on Disease Burden: The Saspar Study
To evaluate the prevalence of probable, confirmed, and severe sarcopenia in spondyloarthritis (SpA), according to the Euro...
Hip Labral Morphological Changes in Patients with Femoroacetabular Impingement Speed Up the Onset of Early Osteoarthritis
Hip Labral Morphological Changes in Patients with Femoroacetabular Impingement Speed Up the Onset of Early Osteoarthritis
Over the last decade, evidence has mounted for a prominent etiologic role of femoroacetabular impingement (FAI) in the dev...
Bone Tissue Evaluation Indicates Abnormal Mineralization in Patients with Autoimmune Polyendocrine Syndrome Type I: Report on Three Cases
Bone Tissue Evaluation Indicates Abnormal Mineralization in Patients with Autoimmune Polyendocrine Syndrome Type I: Report on Three Cases
Autoimmune polyendocrine syndrome type-1 (APS1) is characterized by autoimmune manifestations affecting different organs f...
Advancing Use of DEXA Scans to Quantitatively and Qualitatively Evaluate Lateral Spinal Curves, for Preliminary Identification of Adolescent Idiopathic Scoliosis
Advancing Use of DEXA Scans to Quantitatively and Qualitatively Evaluate Lateral Spinal Curves, for Preliminary Identification of Adolescent Idiopathic Scoliosis
Dual-energy X-ray absorptiometry (DEXA) scan is an emerging screening method for identifying likely adolescent idiopathic ...
Urotensin II can Induce Skeletal Muscle Atrophy Associated with Upregulating Ubiquitin–Proteasome System and Inhibiting the Differentiation of Satellite Cells in CRF Mice
Urotensin II can Induce Skeletal Muscle Atrophy Associated with Upregulating Ubiquitin–Proteasome System and Inhibiting the Differentiation of Satellite Cells in CRF Mice
Skeletal muscle wasting and atrophy is highly prevalent in chronic renal failure (CRF) and increases the risk of mortality...
Association of Polypharmacy and Anticholinergic Burden with Length of Stay in Hospital Amongst Older Adults Admitted with Hip Fractures: A Retrospective Observational Study
Association of Polypharmacy and Anticholinergic Burden with Length of Stay in Hospital Amongst Older Adults Admitted with Hip Fractures: A Retrospective Observational Study
Age-associated multimorbidity and polypharmacy, predispose individuals to falls and consequent hip fractures. We examined ...
Metabolome-Wide Mendelian Randomization Assessing the Causal Relationship Between Blood Metabolites and Bone Mineral Density
Metabolome-Wide Mendelian Randomization Assessing the Causal Relationship Between Blood Metabolites and Bone Mineral Density
Mounting evidence has supported osteoporosis (OP) as a metabolic disorder. Recent metabolomics studies have discovered num...
1α,25-Dihydroxyvitamin D3 Regulates microRNA Packaging in Extracellular Matrix Vesicles and Their Release in the Matrix
1α,25-Dihydroxyvitamin D3 Regulates microRNA Packaging in Extracellular Matrix Vesicles and Their Release in the Matrix
Growth plate chondrocytes are regulated by numerous factors and hormones as they mature during endochondral bone formation...
Mitigating the Denosumab-Induced Rebound Phenomenon with Alternating Short- and Long-Acting Anti-resorptive Therapy in a Young Boy with Severe OI Type VI
Mitigating the Denosumab-Induced Rebound Phenomenon with Alternating Short- and Long-Acting Anti-resorptive Therapy in a Young Boy with Severe OI Type VI
Osteogenesis imperfecta (OI) type VI, a recessively inherited form of OI caused by mutations in SERPINF1, is a severe form...
Analysis of Three-Dimensional Bone Microarchitecture of the Axis Exposes Pronounced Regional Heterogeneity Associated with Clinical Fracture Patterns
Analysis of Three-Dimensional Bone Microarchitecture of the Axis Exposes Pronounced Regional Heterogeneity Associated with Clinical Fracture Patterns
The odontoid process (dens) of the second cervical vertebra (axis) is prone to fracture. While the importance of its skele...
Cross-Calibration of iDXA and pQCT Scanners at Rural and Urban Research Sites in The Gambia, West Africa
Cross-Calibration of iDXA and pQCT Scanners at Rural and Urban Research Sites in The Gambia, West Africa
Between-scanner differences in measures of bone and body composition can obscure or exaggerate physiological differences i...
Surgical Management and Denosumab for Aneurysmal Bone Cysts of the Spine in an Australian Tertiary Paediatric Centre
Surgical Management and Denosumab for Aneurysmal Bone Cysts of the Spine in an Australian Tertiary Paediatric Centre
Aneurysmal bone cysts (ABC) are rare osteolytic, benign but often locally aggressive tumours of the long bones or vertebra...
Bone Microarchitecture and Strength Changes During Teriparatide and Zoledronic Acid Treatment in a Patient with Pregnancy and Lactation-Associated Osteoporosis with Multiple Vertebral Fractures
Bone Microarchitecture and Strength Changes During Teriparatide and Zoledronic Acid Treatment in a Patient with Pregnancy and Lactation-Associated Osteoporosis with Multiple Vertebral Fractures
Pregnancy- and lactation-associated osteoporosis (PLO) is a rare form of osteoporosis, of which the pathogenesis ...
Rescue of High Glucose Impairment of Cultured Human Osteoblasts Using Cinacalcet and Parathyroid Hormone
Rescue of High Glucose Impairment of Cultured Human Osteoblasts Using Cinacalcet and Parathyroid Hormone
Patients with type 2 diabetes mellitus (T2DM) experience a higher risk of fractures despite paradoxically exhibiting norma...
Analysis of Hand Joint Space Morphology in Women and Men with Hereditary Hemochromatosis
Analysis of Hand Joint Space Morphology in Women and Men with Hereditary Hemochromatosis
Hereditary hemochromatosis (HH) causes unbalanced iron deposition in many organs including the joints leading to severe ca...
SHP-1 Protein Tyrosine Phosphatase Affects Early Postnatal Bone Development in Mice
SHP-1 Protein Tyrosine Phosphatase Affects Early Postnatal Bone Development in Mice
The Src homology region 2 domain-containing phosphatase-1 (SHP-1) is an intracellular tyrosine phosphatase that plays a ne...
Reference Intervals for Bone Impact Microindentation in Healthy Adults: A Multi-Centre International Study
Reference Intervals for Bone Impact Microindentation in Healthy Adults: A Multi-Centre International Study
Impact microindentation (IMI) is a novel technique for assessing bone material strength index (BMSi) in vivo, by measuring...
Periosteal Bone Formation Varies with Age in Periostin Null Mice
Periosteal Bone Formation Varies with Age in Periostin Null Mice
Periostin, also known as osteoblast-specific factor 2, is a matricellular protein predominantly expressed at the periosteu...
Extensive and Differential Deterioration of Hip Muscles May Preexist in Older Adults with Hip Fractures: Evidence from a Cross-Sectional Study
Extensive and Differential Deterioration of Hip Muscles May Preexist in Older Adults with Hip Fractures: Evidence from a Cross-Sectional Study
Hip muscles play an increasingly important role in lower limb function with aging. Investigating the deterioration of hip ...
Genotypic Spectrum and its Correlation with Alopecia and Clinical Response in Hereditary Vitamin D Resistant Rickets: Our Experience and Systematic Review
Genotypic Spectrum and its Correlation with Alopecia and Clinical Response in Hereditary Vitamin D Resistant Rickets: Our Experience and Systematic Review
Alopecia in hereditary vitamin D resistant rickets (HVDRR) has some correlation with severe rickets and poor overall respo...
Effect of Bone Resorption Inhibitors on Serum Cholesterol Level and Fracture Risk in Osteoporosis: Randomized Comparative Study Between Minodronic Acid and Raloxifene
Effect of Bone Resorption Inhibitors on Serum Cholesterol Level and Fracture Risk in Osteoporosis: Randomized Comparative Study Between Minodronic Acid and Raloxifene
The positive link between osteoporosis and hypercholesterolemia has been documented, and bone resorption inhibitors, such ...
Vitamin D-Dependent Rickets Type 3: A Case Report and Systematic Review
Vitamin D-Dependent Rickets Type 3: A Case Report and Systematic Review
Although vitamin D deficiency resulting from insufficient sunlight exposure or inadequate dietary vitamin D intake is the ...
Contributions of Resin Cast Etching to Visualising the Osteocyte Lacuno-Canalicular Network Architecture in Bone Biology and Tissue Engineering
Contributions of Resin Cast Etching to Visualising the Osteocyte Lacuno-Canalicular Network Architecture in Bone Biology and Tissue Engineering
Recent years have witnessed an evolution of imaging technologies towards sophisticated approaches for visualising cells wi...
Biochemical Markers of Musculoskeletal Health and Aging to be Assessed in Clinical Trials of Drugs Aiming at the Treatment of Sarcopenia: Consensus Paper from an Expert Group Meeting Organized by the European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO) and the Centre Académique de Recherche et d'Expérimentation en Santé (CARES SPRL), Under the Auspices of the World Health Organization Collaborating Center for the Epidemiology of Musculoskeletal Conditions and Aging
Biochemical Markers of Musculoskeletal Health and Aging to be Assessed in Clinical Trials of Drugs Aiming at the Treatment of Sarcopenia: Consensus Paper from an Expert Group Meeting Organized by the European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO) and the Centre Académique de Recherche et d'Expérimentation en Santé (CARES SPRL), Under the Auspices of the World Health Organization Collaborating Center for the Epidemiology of Musculoskeletal Conditions and Aging
In clinical trials, biochemical markers provide useful information on the drug’s mode of action, therapeutic respons...
Contemporary Advances in Computer-Assisted Bone Histomorphometry and Identification of Bone Cells in Culture
Contemporary Advances in Computer-Assisted Bone Histomorphometry and Identification of Bone Cells in Culture
Static and dynamic bone histomorphometry and identification of bone cells in culture are labor-intensive and highly repeti...
Asperosaponin VI Protects Against Bone Loss Due to Hindlimb Unloading in Skeletally Growing Mice Through Regulating Microbial Dysbiosis Altering the 5-HT Pathway
Asperosaponin VI Protects Against Bone Loss Due to Hindlimb Unloading in Skeletally Growing Mice Through Regulating Microbial Dysbiosis Altering the 5-HT Pathway
Osteoporosis is a complex multifactorial disease that can lead to an increased risk of fracture. However, selective and ef...
The Association of Cardiovascular Diseases Risk Scores and Osteosarcopenia Among Older Adult Populations: The Results of Bushehr Elderly Health (BEH) Program
The Association of Cardiovascular Diseases Risk Scores and Osteosarcopenia Among Older Adult Populations: The Results of Bushehr Elderly Health (BEH) Program
Considering the association of cardiovascular disease (CVD) with both osteoporosis and sarcopenia, this study aimed to exp...
Role of the Clinical Laboratory in the Assessment of Metabolic Musculoskeletal Diseases
Role of the Clinical Laboratory in the Assessment of Metabolic Musculoskeletal Diseases
Clinicians rely on laboratory results daily to treat and monitor patients. In fact, biomarkers are inexpensive, non-invasi...
A Novel De Novo Frameshift Pathogenic Variant in the FAM111B Resulting in Progressive Osseous Heteroplasia Phenotype
A Novel De Novo Frameshift Pathogenic Variant in the FAM111B Resulting in Progressive Osseous Heteroplasia Phenotype
Progressive osseous heteroplasia (POH) is a rare, debilitating disorder characterized by heterotopic ossification in the s...
Causal Effects of Plasma Proteome on Osteoporosis and Osteoarthritis
Causal Effects of Plasma Proteome on Osteoporosis and Osteoarthritis
The two-sample Mendelian randomization (MR) study revealed a causal association of plasma proteins with osteoporosis (OP) ...
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