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Identifying Gut Microbiome Features that Predict Responsiveness Toward a Prebiotic Capable of Increasing Calcium Absorption: A Pilot Study
Identifying Gut Microbiome Features that Predict Responsiveness Toward a Prebiotic Capable of Increasing Calcium Absorption: A Pilot Study
Previously, we demonstrated that prebiotics may provide a complementary strategy for increasing calcium (Ca) absorption in...
Absence of E2f1 Negates Pro-osteogenic Impacts of p21 Absence
Absence of E2f1 Negates Pro-osteogenic Impacts of p21 Absence
Loss of p21 leads to increased bone formation post-injury; however, the mechanism(s) by which this occurs remains undeterm...
Effects of Testosterone in Mediating the Relationship Between Daytime Napping and Osteoporosis in European Populations: A Mendelian Randomization Study
Effects of Testosterone in Mediating the Relationship Between Daytime Napping and Osteoporosis in European Populations: A Mendelian Randomization Study
We aimed to explore the causal effect of daytime napping on the risk of osteoporosis and the mediation role of testosteron...
Extra-Skeletal Manifestations in Osteogenesis Imperfecta Mouse Models
Extra-Skeletal Manifestations in Osteogenesis Imperfecta Mouse Models
Osteogenesis imperfecta (OI) is a rare heritable connective tissue disorder of skeletal fragility with an incidence of rou...
Metabolic and Skeletal Characterization of the KK/Ay Mouse Model—A Polygenic Mutation Model of Obese Type 2 Diabetes
Metabolic and Skeletal Characterization of the KK/Ay Mouse Model—A Polygenic Mutation Model of Obese Type 2 Diabetes
Type 2 diabetes (T2D) increases fracture incidence and fracture-related mortality rates (KK.Cg-Ay/J. The Jackson Laborator...
Probiotics Supplements Improve the Sarcopenia-Related Quality of Life in Older Adults with Age-Related Muscle Decline
Probiotics Supplements Improve the Sarcopenia-Related Quality of Life in Older Adults with Age-Related Muscle Decline
A pathological increase in intestinal leak is implicated in age-associated muscle loss, termed sarcopenia, and reduced sar...
Neuropathic and Nociplastic Pain Profiles are Common in Adult Chronic Nonbacterial Osteitis (CNO)
Neuropathic and Nociplastic Pain Profiles are Common in Adult Chronic Nonbacterial Osteitis (CNO)
Chronic nonbacterial osteitis (CNO) is a rare musculoskeletal disease causing chronic bone pain. It is known that chronic ...
Development and Internal Validation of a Multivariable Prediction Model for Mortality After Hip Fracture with Machine Learning Techniques
Development and Internal Validation of a Multivariable Prediction Model for Mortality After Hip Fracture with Machine Learning Techniques
In order to estimate the likelihood of 1, 3, 6 and 12 month mortality in patients with hip fractures, we applied ...
The Impact of Non-alcohol Fatty Liver Disease on Bone Mineral Density is Mediated by Sclerostin by Mendelian Randomization Study
The Impact of Non-alcohol Fatty Liver Disease on Bone Mineral Density is Mediated by Sclerostin by Mendelian Randomization Study
Non-alcoholic fatty liver disease (NAFLD) has been found to be associated with osteoporosis (OP) in observational studies....
Correction to: BMP2 Modified by the m6A Demethylation Enzyme ALKBH5 in the Ossification of the Ligamentum Flavum Through the AKT Signaling Pathway
Correction to: BMP2 Modified by the m6A Demethylation Enzyme ALKBH5 in the Ossification of the Ligamentum Flavum Through the AKT Signaling Pathway
Cite this articleWang, HF., Kuang, Mj., Han, Sj. et al. Correction to: BMP2 Modified by the m6A Demethylation Enzyme ALKBH...
Opportunistic Identification of Vertebral Compression Fractures on CT Scans of the Chest and Abdomen, Using an AI Algorithm, in a Real-Life Setting
Opportunistic Identification of Vertebral Compression Fractures on CT Scans of the Chest and Abdomen, Using an AI Algorithm, in a Real-Life Setting
This study evaluated the performance of a vertebral fracture detection algorithm (HealthVCF) in a real-life setting and as...
Systemic Inflammatory Regulators Associated with Osteoporosis: A Bidirectional Mendelian Randomization Study
Systemic Inflammatory Regulators Associated with Osteoporosis: A Bidirectional Mendelian Randomization Study
To elucidate the precise upstream and downstream regulatory mechanisms of inflammatory factors in osteoporosis (OP) progre...
Secular Trends in Peak Bone Mineral Density: The National Health and Nutrition Examination Survey 1999–2018
Secular Trends in Peak Bone Mineral Density: The National Health and Nutrition Examination Survey 1999–2018
Peak bone mineral density (BMD) is one of the most important factors influencing the development of osteoporosis. It was p...
Paget Disease of Bone Harboring Bone Metastatic Neuroendocrine Cancer: A Case Report
Paget Disease of Bone Harboring Bone Metastatic Neuroendocrine Cancer: A Case Report
In this case report, we describe an uncommon case of neuroendocrine cancer of unknown origin began with cauda equina syndr...
Pre-proenkephalin 1 is Downregulated Under Unloading and is Involved in Osteoblast Biology
Pre-proenkephalin 1 is Downregulated Under Unloading and is Involved in Osteoblast Biology
Pre-proenkephalin 1 (Penk1) is a pro-neuropeptide that belongs to the typical opioid peptide’s family, having analge...
Postoperative Bisphosphonates Use is Associated with Reduced Adverse Outcomes After Primary Total Joint Arthroplasty of Hip and Knee: A Nationwide Population-Based Cohort Study
Postoperative Bisphosphonates Use is Associated with Reduced Adverse Outcomes After Primary Total Joint Arthroplasty of Hip and Knee: A Nationwide Population-Based Cohort Study
Bisphosphonates have been associated with a decreased risk of revision surgery after total joint arthroplasty of the hip o...
Differences in Vertebral Morphology and bone Mineral Density between Grade 1 Vertebral Fracture and Non-Fractured Participants in the Chinese Population
Differences in Vertebral Morphology and bone Mineral Density between Grade 1 Vertebral Fracture and Non-Fractured Participants in the Chinese Population
Purpose: To investigate the difference in vertebral morphology and bone mineral density (BMD) between grade 1 VFs and non-...
The PDE4 Inhibitors Roflumilast and Rolipram Rescue ADO2 Osteoclast Resorption Dysfunction
The PDE4 Inhibitors Roflumilast and Rolipram Rescue ADO2 Osteoclast Resorption Dysfunction
Autosomal Dominant Osteopetrosis type II (ADO2) is a rare bone disease of impaired osteoclastic bone resorption caused by ...
Roles of Plasminogen Activator Inhibitor-1 in Heterotopic Ossification Induced by Achilles Tenotomy in Thermal Injured Mice
Roles of Plasminogen Activator Inhibitor-1 in Heterotopic Ossification Induced by Achilles Tenotomy in Thermal Injured Mice
Heterotopic ossification (HO) is the process by which ectopic bone forms at an extraskeletal site. Inflammatory conditions...
Bone Density and Trabecular Bone Score Decline Rapidly in the First Year After Bone Marrow Transplantation with a Marked Increase in 10-Year Fracture Risk
Bone Density and Trabecular Bone Score Decline Rapidly in the First Year After Bone Marrow Transplantation with a Marked Increase in 10-Year Fracture Risk
As outcomes from allogeneic bone marrow transplantation (BMT) have improved, prevention of long-term complications, such a...
Cost-Effectiveness and Clinical Outcomes of Secondary Hyperparathyroidism Treatments in Patients with Chronic Kidney Disease
Cost-Effectiveness and Clinical Outcomes of Secondary Hyperparathyroidism Treatments in Patients with Chronic Kidney Disease
The study addresses the challenge of treating secondary hyperparathyroidism (SHPT) in chronic kidney disease (CKD) patient...
The Relationship Between Systemic Lupus Erythematosus and Osteoporosis Based on Different Ethnic Groups: a Two-Sample Mendelian Randomization Analysis
The Relationship Between Systemic Lupus Erythematosus and Osteoporosis Based on Different Ethnic Groups: a Two-Sample Mendelian Randomization Analysis
The previous observational studies could not overcome the effects of confounding variables and reverse causality. We aimed...
The Relationship Among Probable SARCopenia, Osteoporosis and SuprasPinatus Tendon Tears in Postmenopausal Women: The SARCOSP Study
The Relationship Among Probable SARCopenia, Osteoporosis and SuprasPinatus Tendon Tears in Postmenopausal Women: The SARCOSP Study
We aimed to investigate the relationship among probable sarcopenia, osteoporosis (OP) and supraspinatus tendon (SSP) tears...
Trend and Seasonality of Hip Fractures in Catalonia, Spain: Exploring the Influence of Climate
Trend and Seasonality of Hip Fractures in Catalonia, Spain: Exploring the Influence of Climate
To describe the secular trend and seasonality of the incidence of hip fracture (HF) and its relationship with climatic var...
The Effect of Rheumatoid Arthritis on Features Associated with Sarcopenia: A Mendelian Randomization Study
The Effect of Rheumatoid Arthritis on Features Associated with Sarcopenia: A Mendelian Randomization Study
Previous epidemiological evidence suggests rheumatoid arthritis is associated with sarcopenia-related features. However, m...
Regulatory Pathways in Growth Plate Chondrocytes that Are Impacted by Matrix Vesicle microRNA Identified by Targeted RISC Pulldown and Sequencing of the Resulting Transcriptome
Regulatory Pathways in Growth Plate Chondrocytes that Are Impacted by Matrix Vesicle microRNA Identified by Targeted RISC Pulldown and Sequencing of the Resulting Transcriptome
During endochondral bone formation, growth plate chondrocytes are differentially regulated by various factors and hormones...
Comparison of the Clinical Outcomes of Vesselplasty vs. Percutaneous Vertebroplasty for the Treatment of Neurologically Intact Osteoporotic Kümmell’s Disease: A Retrospective Study
Comparison of the Clinical Outcomes of Vesselplasty vs. Percutaneous Vertebroplasty for the Treatment of Neurologically Intact Osteoporotic Kümmell’s Disease: A Retrospective Study
Kummell’s disease (KD) is a rare clinical complication of osteoporotic vertebral compression fractures (OVCFs). Mini...
Effect of Roflumilast, a Selective PDE4 Inhibitor, on Bone Phenotypes in ADO2 Mice
Effect of Roflumilast, a Selective PDE4 Inhibitor, on Bone Phenotypes in ADO2 Mice
Autosomal Dominant Osteopetrosis type II (ADO2) is a rare bone disease of impaired osteoclastic bone resorption that usual...
Osteosarcopenia: Prevalence and 10-Year Fracture and Mortality Risk – A Longitudinal, Population-Based Study of 75-Year-Old Women
Osteosarcopenia: Prevalence and 10-Year Fracture and Mortality Risk – A Longitudinal, Population-Based Study of 75-Year-Old Women
Osteosarcopenia is the coexistence of low bone mass and sarcopenia. In older women, its prevalence is not well described, ...
Biochemical Clusters as Substitutes of Bone Biopsies in Kidney Transplant Patients
Biochemical Clusters as Substitutes of Bone Biopsies in Kidney Transplant Patients
Bone and mineral metabolism abnormalities are frequent in kidney transplant recipients and have been associated with cardi...
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