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Semaphorin 3A on Osteoporosis: An Overreview of the Literature
Semaphorin 3A on Osteoporosis: An Overreview of the Literature
Semaphorin 3A (Sema3A) is a signaling protein that has attracted increasing attention in recent years for its important ro...
Fracture Risk Assessment in Metabolic Syndrome in Terms of Secondary Osteoporosis Potential. A Narrative Review
Fracture Risk Assessment in Metabolic Syndrome in Terms of Secondary Osteoporosis Potential. A Narrative Review
Osteoporosis is a major global public health problem with the associated bone fractures contributing significantly to both...
Long-Term Changes in Parameters of Bone Quality in Kidney Transplant Recipients Treated with Denosumab
Long-Term Changes in Parameters of Bone Quality in Kidney Transplant Recipients Treated with Denosumab
Kidney transplant recipients (KTRs) have an elevated fracture risk. While dual-energy X-ray absorptiometry (DXA) is common...
Severe Osteoporosis in an Adult Subject with RNU4-2 Gene Mutation
Severe Osteoporosis in an Adult Subject with RNU4-2 Gene Mutation
Recent studies have shown that RNU4-2 pathogenic gene variants are among the most frequent causes of monogenic neurodevelo...
Basic and Clinical Scientists Working Together—Do We Make the Best of Both Worlds?
Basic and Clinical Scientists Working Together—Do We Make the Best of Both Worlds?
Musculoskeletal disorders, affecting as many as 1.3 billion people worldwide, are the leading cause of disability and impo...
Impact of Resistance Training on Bone During 40% Caloric Restriction in Growing Female Rats
Impact of Resistance Training on Bone During 40% Caloric Restriction in Growing Female Rats
There is a growing trend in the use of severe caloric restrictive diets among normal weight young females that can jeopard...
Unusual Association of Partial Fanconi Syndrome and Tumor-Induced Osteomalacia Revealed by Multiple Vertebral Fractures
Unusual Association of Partial Fanconi Syndrome and Tumor-Induced Osteomalacia Revealed by Multiple Vertebral Fractures
Tumor-induced osteomalacia (TIO) is a rare acquired paraneoplastic syndrome caused by a mesenchymal tumor secreting a phos...
Differences in Body Composition, Bone Density, and Tibial Microarchitecture in Division I Female Athletes Participating in Different Impact Loading Sports
Differences in Body Composition, Bone Density, and Tibial Microarchitecture in Division I Female Athletes Participating in Different Impact Loading Sports
Sport participation affects body composition and bone health, but the association between sport, body composition, and bon...
18F-Sodium Fluoride PET/CT as a Tool to Assess Enthesopathies in X-Linked Hypophosphatemia
18F-Sodium Fluoride PET/CT as a Tool to Assess Enthesopathies in X-Linked Hypophosphatemia
X-linked hypophosphatemia (XLH) is a rare metabolic disorder characterized by elevated FGF23 and chronic hypophosphatemia,...
The Multifactorial Relationship Between Bone Tissue Water and Stiffness at the Proximal Femur
The Multifactorial Relationship Between Bone Tissue Water and Stiffness at the Proximal Femur
Bone mechanical function is determined by multiple factors, some of which are still being elucidated. Here, we present a m...
Tibial Skeletal Adaptations in Male and Female Marine Corps Officer Candidates Undergoing 10 Weeks of Military Training
Tibial Skeletal Adaptations in Male and Female Marine Corps Officer Candidates Undergoing 10 Weeks of Military Training
Military training improves tibial density, structure, and estimated strength; however, men and women may adapt differently...
Conditional Deletion of Gremlin-1 in Cathepsin K-expressing Mature Osteoclasts Altered the Skeletal Response to Calcium Depletion in Sex-Dependent Manner
Conditional Deletion of Gremlin-1 in Cathepsin K-expressing Mature Osteoclasts Altered the Skeletal Response to Calcium Depletion in Sex-Dependent Manner
This study assessed the novel concept that osteoclast-derived Grem1 has regulatory functions in the skeletal response to c...
Effect of Eight Months of Swimming on Bone Quality of Different Anatomical Regions: A Study on Wistar Rat Models
Effect of Eight Months of Swimming on Bone Quality of Different Anatomical Regions: A Study on Wistar Rat Models
Swimming is a popular sport with several health benefits, but its effects on bone quality are controversial possibly due t...
Administration of Bisphosphonate Preparations to Mice with Mild-type Hypophosphatasia Reduces the Quality of Spontaneous Locomotor Activity
Administration of Bisphosphonate Preparations to Mice with Mild-type Hypophosphatasia Reduces the Quality of Spontaneous Locomotor Activity
Hypophosphatasia (HPP) is a congenital bone disease caused by tissue-nonspecific mutations in the alkaline phosphatase gen...
Serum Pentosidine in Relation to Obesity in Patients with Type 2 Diabetes and Healthy Controls
Serum Pentosidine in Relation to Obesity in Patients with Type 2 Diabetes and Healthy Controls
Pentosidine (PEN), a surrogate marker of advanced glycation end-product formation, reflects increased non-enzymatic cross-...
Adipose-Derived Stromal Cell Conditioned Medium on Bone Remodeling: Insights from a 3D Osteoblast–Osteoclast Co-Culture Model
Adipose-Derived Stromal Cell Conditioned Medium on Bone Remodeling: Insights from a 3D Osteoblast–Osteoclast Co-Culture Model
This study describes the potential of the conditioned medium (CM) from adipose-derived mesenchymal stromal cells (ASCs) to...
The Delicate Balancing of Pros and Cons in the Surgical Management of Hyperparathyroidism in a Young Female with Germline Variant in the CDC73 Gene
The Delicate Balancing of Pros and Cons in the Surgical Management of Hyperparathyroidism in a Young Female with Germline Variant in the CDC73 Gene
Hyperparathyroidism‐jaw tumor syndrome is a rare form of syndromic primary hyperparathyroidism. We describe a young ...
Bone Disease Associated with Inactivating Aromatase Mutations and its Management
Bone Disease Associated with Inactivating Aromatase Mutations and its Management
Aromatase deficiency (ORPHA:91; OMIM: 613,546) is a rare, autosomal recessive disorder due to loss of function mutations i...
The Management of Bone Defects in Rett Syndrome
The Management of Bone Defects in Rett Syndrome
Rett syndrome (RS) is a rare neurodevelopmental disorder primarily caused by mutations in the X-linked methyl-CpG binding ...
Helicobacter pylori-Related Chronic Gastritis as a Risk Factor for Lower Bone Mineral Density
Helicobacter pylori-Related Chronic Gastritis as a Risk Factor for Lower Bone Mineral Density
We evaluated the role of Helicobacter pylori (H. pylori)-related chronic gastritis in the development of...
Long-Term Natural Hydroxyapatite and Synthetic Collagen Hydroxyapatite Enhance Bone Regeneration and Implant Fixation Similar to Allograft in a Sheep Model of Implant Integration
Long-Term Natural Hydroxyapatite and Synthetic Collagen Hydroxyapatite Enhance Bone Regeneration and Implant Fixation Similar to Allograft in a Sheep Model of Implant Integration
There is an increasing demand for a suitable bone substitute to replace current clinical gold standard autografts or allog...
Treatment Advances in Tumor-Induced Osteomalacia
Treatment Advances in Tumor-Induced Osteomalacia
Tumor-induced osteomalacia (TIO) is a rare paraneoplastic syndrome caused by hypersecretion of fibroblast growth factor 23...
Effects of Pregnancy and Lactation on Bone Microstructure and Material Properties in a Rat Model of Bariatric Surgery
Effects of Pregnancy and Lactation on Bone Microstructure and Material Properties in a Rat Model of Bariatric Surgery
Obesity is a major public health issue worldwide. Despite various approaches to weight loss, the most effective technique ...
A Qualitative Approach to Quality of Life in Fibrous Bone Dysplasia /McCune Albright Syndrome: Looking Beyond Quantitative Analysis
A Qualitative Approach to Quality of Life in Fibrous Bone Dysplasia /McCune Albright Syndrome: Looking Beyond Quantitative Analysis
This study explores FD/MAS patient’s perceptions about their disease and its impact on their quality of life. We hav...
The Association between Social Support and Musculoskeletal Health in Community-Dwelling Older Adults: Findings from the Hertfordshire Cohort Study
The Association between Social Support and Musculoskeletal Health in Community-Dwelling Older Adults: Findings from the Hertfordshire Cohort Study
Previous studies suggest social support is associated with musculoskeletal health in later life. We explored this relation...
Base of Skull & Spinal Canal Narrowing in an Adolescent with Autosomal Recessive Hypophosphatemic Rickets Type 2
Base of Skull & Spinal Canal Narrowing in an Adolescent with Autosomal Recessive Hypophosphatemic Rickets Type 2
Autosomal recessive hypophosphatemic rickets type 2 (ARHR2) is an uncommon hereditary form of rickets characterised by chr...
Conflating the Operational Definition of Osteoporosis with Intervention Thresholds
Conflating the Operational Definition of Osteoporosis with Intervention Thresholds
Wáng YXJ, Griffith JF, Blake GM, Diacinti D, Xiao BH, Yu W, Su Y, Jiang Y, Guglielmi G, Guermazi A, Kwok TCY (2024) Revisi...
Characterization of a Novel Col1a1G643S/+ Osteogenesis Imperfecta Mouse Model with Insights into Skeletal Phenotype, Fragility, and Therapeutic Evaluations
Characterization of a Novel Col1a1G643S/+ Osteogenesis Imperfecta Mouse Model with Insights into Skeletal Phenotype, Fragility, and Therapeutic Evaluations
Osteogenesis imperfecta (OI) is an inheritable skeletal disorder characterized by bone fragility often caused by pathogeni...
Nanostructural Analysis of Age-Related Changes Affecting Human Dentin
Nanostructural Analysis of Age-Related Changes Affecting Human Dentin
Human dentin performs its function throughout life, even though it is not remodeled like bone. Therefore, dentin must have...
Multi-trait Genome-Wide Analysis Identified 20 Novel Loci for Sarcopenia-Related Traits in UK Biobank
Multi-trait Genome-Wide Analysis Identified 20 Novel Loci for Sarcopenia-Related Traits in UK Biobank
This study aims to identify novel loci associated with sarcopenia-related traits in UK Biobank (UKB) through multi-trait g...
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