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The PATCH study: Prevalence of Hearing Loss During Ageing and Treatment Choices in Osteogenesis Imperfecta: A Danish Nationwide Register-Based Cohort Study
The PATCH study: Prevalence of Hearing Loss During Ageing and Treatment Choices in Osteogenesis Imperfecta: A Danish Nationwide Register-Based Cohort Study
Osteogenesis imperfecta (OI) is a group of rare hereditary collagen disorders. Hearing loss (HL) is a known complication l...
Bone Fragility in High Fat Diet-induced Obesity is Partially Independent of Type 2 Diabetes in Mice
Bone Fragility in High Fat Diet-induced Obesity is Partially Independent of Type 2 Diabetes in Mice
Obesity and type 2 diabetes (T2D) are risk factors for fragility fractures. It is unknown whether this elevated r...
3D U-Net Neural Network Architecture-Assisted LDCT to Acquire Vertebral Morphology Parameters: A Vertebral Morphology Comprehensive Analysis in a Chinese Population
3D U-Net Neural Network Architecture-Assisted LDCT to Acquire Vertebral Morphology Parameters: A Vertebral Morphology Comprehensive Analysis in a Chinese Population
To evaluate the feasibility of acquiring vertebral height from chest low-dose computed tomography (LDCT) images using an a...
Suppression of YAP Ameliorates Cartilage Degeneration in Ankle Osteoarthritis via Modulation of the Wnt/β-Catenin Signaling Pathway
Suppression of YAP Ameliorates Cartilage Degeneration in Ankle Osteoarthritis via Modulation of the Wnt/β-Catenin Signaling Pathway
Ankle osteoarthritis is a relatively understudied condition and the molecular mechanisms involved in its development are n...
Burosumab Efficacy and Safety in Patients with X-Linked Hypophosphatemia: Systematic Review and Meta-analysis of Real-World Data
Burosumab Efficacy and Safety in Patients with X-Linked Hypophosphatemia: Systematic Review and Meta-analysis of Real-World Data
To assess the efficacy and safety of burosumab in children and adults with X-linked hypophosphatemia based on real-world e...
A Dyadic Nosology for Osteogenesis Imperfecta and Bone Fragility Syndromes 2024
A Dyadic Nosology for Osteogenesis Imperfecta and Bone Fragility Syndromes 2024
In 2023 following extensive consultation with key stakeholders, the expert Nosology Working Group of the International Ske...
Bone Turnover Markers and Wnt Signaling Modulators in Early Complex Regional Pain Syndrome. A Pre-specified Observational Study
Bone Turnover Markers and Wnt Signaling Modulators in Early Complex Regional Pain Syndrome. A Pre-specified Observational Study
To explore serum levels of some bone turnover markers and the involvement of the Wnt signaling in CRPS-1. Query ID="Q...
Clinical Characteristics, Therapeutic Options, and Outcomes in Hyperphosphatemic Tumoral Calcinosis: A Systematic Review
Clinical Characteristics, Therapeutic Options, and Outcomes in Hyperphosphatemic Tumoral Calcinosis: A Systematic Review
This systematic review was performed to understand better the myriad presentations, various therapeutic options, response ...
Unraveling the Mechanisms of Hypertrophy-Induced Matrix Mineralization and Modifications in Articular Chondrocytes
Unraveling the Mechanisms of Hypertrophy-Induced Matrix Mineralization and Modifications in Articular Chondrocytes
Chondrocyte hypertrophic differentiation is a main event leading to articular cartilage degradation in osteoarthritis. It ...
Long-Term Follow-Up Data of Tumor-Induced Osteomalacia Managed with Surgery and/or Radiofrequency Ablation from a Single Center
Long-Term Follow-Up Data of Tumor-Induced Osteomalacia Managed with Surgery and/or Radiofrequency Ablation from a Single Center
Data on radiofrequency ablation (RFA) in tumor-induced osteomalacia (TIO) are restricted to case reports (~ 11 patie...
The Decline of Paget’s Disease of Bone and Domestic Coal Use—A Hypothesis
The Decline of Paget’s Disease of Bone and Domestic Coal Use—A Hypothesis
The cause of Paget’s disease of bone (PDB) is unknown. It emerged as a distinct entity in Britain in the late ninete...
Effect of Chronic Kidney Disease on All-Cause Mortality After Hip Fracture Surgery: A Retrospective Cohort Study
Effect of Chronic Kidney Disease on All-Cause Mortality After Hip Fracture Surgery: A Retrospective Cohort Study
In this retrospective cohort study, we investigated: (1) The impact of comorbid chronic kidney disease (CKD) on postoperat...
Enzymatic and Non-enzymatic Collagen Cross-Links and Fracture Occurrence in Type 1 Diabetes Patients
Enzymatic and Non-enzymatic Collagen Cross-Links and Fracture Occurrence in Type 1 Diabetes Patients
Increased fracture risk in type 1 diabetes (T1D) patients is not fully captured by bone mineral density (BMD) by DXA. Adva...
Two Weeks of Continuous Opioid Treatment in an Adenine-Induced Mouse Model of Chronic Kidney Disease Exacerbates the Bone Inflammatory State and Increases Osteoclasts
Two Weeks of Continuous Opioid Treatment in an Adenine-Induced Mouse Model of Chronic Kidney Disease Exacerbates the Bone Inflammatory State and Increases Osteoclasts
Patients with chronic kidney disease (CKD) report high pain levels, but reduced renal clearance eliminates many analgesic ...
Glucagon-like Peptide-1 Receptor Agonists and Diabetic Osteopathy: Another Positive Effect of Incretines? A 12 Months Longitudinal Study
Glucagon-like Peptide-1 Receptor Agonists and Diabetic Osteopathy: Another Positive Effect of Incretines? A 12 Months Longitudinal Study
Diabetic osteopathy is a frequent complication in patients with type 2 diabetes mellitus (T2DM). The association between T...
Osteogenesis Imperfecta: Skeletal and Non-skeletal Challenges in Adulthood
Osteogenesis Imperfecta: Skeletal and Non-skeletal Challenges in Adulthood
Osteogenesis imperfecta (OI) is a Mendelian connective tissue disorder associated with increased bone fragility and other ...
Patients with Periprosthetic Femoral Hip Fractures are Commonly Classified as Having Osteoporosis Based on DXA Measurements
Patients with Periprosthetic Femoral Hip Fractures are Commonly Classified as Having Osteoporosis Based on DXA Measurements
Periprosthetic femoral hip fractures are subject to an increasing incidence and are often considered to be relate...
Etiological Mechanisms and Genetic/Biological Modulation Related to PTH1R in Primary Failure of Tooth Eruption
Etiological Mechanisms and Genetic/Biological Modulation Related to PTH1R in Primary Failure of Tooth Eruption
Primary failure of eruption (PFE) is a rare disorder that is characterized by the inability of a molar tooth/teeth to erup...
Spondyloocular Syndrome: First Case of Rare Osseous and Ocular Syndrome from India with Novel Mutation and Expanded Phenotypic Spectrum
Spondyloocular Syndrome: First Case of Rare Osseous and Ocular Syndrome from India with Novel Mutation and Expanded Phenotypic Spectrum
Spondyloocular syndrome (SOS) is a rare autosomal recessive skeletal and ocular disorder with variable phenotypes. It is c...
The Association of Intestinal Leak with Sarcopenia and Physical Disability in Patients with Various Stages of Chronic Kidney Disease
The Association of Intestinal Leak with Sarcopenia and Physical Disability in Patients with Various Stages of Chronic Kidney Disease
Sarcopenia is related to disease severity in chronic kidney disease (CKD) patients; however, its pathophysiology remains p...
A Rare Association Between Osteomalacia, Phosphaturic Mesenchymal Tumor, and Ovarian Cancer: A Case Report and Literature Review
A Rare Association Between Osteomalacia, Phosphaturic Mesenchymal Tumor, and Ovarian Cancer: A Case Report and Literature Review
Tumor-induced osteomalacia (TIO) is a rare paraneoplastic syndrome characterized by hypophosphatemia, bone mineralization ...
Preventive Effects of Dental Pulp Stem Cell-conditioned Media on Anti-RANKL Antibody-Related Osteonecrosis of the Jaw
Preventive Effects of Dental Pulp Stem Cell-conditioned Media on Anti-RANKL Antibody-Related Osteonecrosis of the Jaw
Medication-related osteonecrosis of the jaw is a serious disease occurring in patients with cancer and osteoporosis, who a...
The Causal Relationship between PCSK9 Inhibitors and Osteoporosis Based on Drug-Targeted Mendelian Combined Mediation Analysis
The Causal Relationship between PCSK9 Inhibitors and Osteoporosis Based on Drug-Targeted Mendelian Combined Mediation Analysis
PCSK9 inhibitors have been shown to lower serum low density lipoprotein cholesterol (LDL-C) levels and a...
Risk of Malignant Neoplasm in Patients with Primary Hyperparathyroidism: A Systematic Review and Meta-analysis
Risk of Malignant Neoplasm in Patients with Primary Hyperparathyroidism: A Systematic Review and Meta-analysis
This study aimed to evaluate the prevalence and risk of malignant neoplasm in primary hyperparathyroidism (PHPT) patients....
Association Between Changes in Sleep, Nap Duration and Bone Mineral Density in Mexican Adults
Association Between Changes in Sleep, Nap Duration and Bone Mineral Density in Mexican Adults
Studies have found associations between sleep, nap duration, and bone mineral density (BMD). However, the longitudinal rel...
Subchondral Bone Osteocyte Lacunae Morphology in End-Stage Osteoarthritis of the Human Tibial Plateau
Subchondral Bone Osteocyte Lacunae Morphology in End-Stage Osteoarthritis of the Human Tibial Plateau
Subchondral bone remodeling, mediated by osteocytes within the lacuno-canalicular network, plays a crucial role in osteoar...
Genetic Prediction of Osteoporosis by Anti-Müllerian Hormone Levels and Reproductive Factors in Women: A Mendelian Randomization Study
Genetic Prediction of Osteoporosis by Anti-Müllerian Hormone Levels and Reproductive Factors in Women: A Mendelian Randomization Study
Previous observational studies have suggested that anti-Müllerian hormone (AMH) and reproductive factors are linked t...
Protective Effects of β-Blockers on Bone in Older Adults with Dementia
Protective Effects of β-Blockers on Bone in Older Adults with Dementia
Increased β-adrenergic receptor activity has been hypothesized to cause bone loss in those with dementia. We investig...
Long-Term Bone Mineral Density Changes in Kidney Transplant Recipients Treated with Denosumab: A Retrospective Study with Nonequivalent Control Group
Long-Term Bone Mineral Density Changes in Kidney Transplant Recipients Treated with Denosumab: A Retrospective Study with Nonequivalent Control Group
Data on the effectiveness of denosumab on osteoporosis after kidney transplantation are limited. We investigated the long-...
OPN, BSP, and Bone Quality—Structural, Biochemical, and Biomechanical Assessment in OPN−/−, BSP−/−, and DKO Mice
OPN, BSP, and Bone Quality—Structural, Biochemical, and Biomechanical Assessment in OPN−/−, BSP−/−, and DKO Mice
Osteopontin (OPN) and Bone Sialoprotein (BSP), abundantly expressed by osteoblasts and osteoclasts, appear to have importa...
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