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Genetics aspect of vitamin C (Ascorbic Acid) biosynthesis and signaling pathways in fruits and vegetables crops
Genetics aspect of vitamin C (Ascorbic Acid) biosynthesis and signaling pathways in fruits and vegetables crops
Vitamin C, also known as ascorbic acid, is an essential nutrient that plays a critical role in many physiological processe...
Targeting nucleotide metabolic pathways in colorectal cancer by integrating scRNA-seq, spatial transcriptome, and bulk RNA-seq data
Targeting nucleotide metabolic pathways in colorectal cancer by integrating scRNA-seq, spatial transcriptome, and bulk RNA-seq data
Colorectal cancer is a malignant tumor of the digestive system originating from abnormal cell proliferation in the colon o...
Psilostachyin C reduces malignant properties of hepatocellular carcinoma cells by blocking CREBBP-mediated transcription of GATAD2B
Psilostachyin C reduces malignant properties of hepatocellular carcinoma cells by blocking CREBBP-mediated transcription of GATAD2B
Hepatocellular carcinoma (HCC) is a leading cause of cancer-related mortality globally. Many herbal medicines and their bi...
A review of the potential involvement of small RNAs in transgenerational abiotic stress memory in plants
A review of the potential involvement of small RNAs in transgenerational abiotic stress memory in plants
Crop production is increasingly threatened by the escalating weather events and rising temperatures associated with global...
CRISPR/Cas9 targeted mutations of OsDSG1 gene enhanced salt tolerance in rice
CRISPR/Cas9 targeted mutations of OsDSG1 gene enhanced salt tolerance in rice
Salinization is one of the leading causes of arable land shrinkage and rice yield decline, recently. Therefore, developing...
MATN2 overexpression suppresses tumor growth in ovarian cancer via PTEN/PI3K/AKT pathway
MATN2 overexpression suppresses tumor growth in ovarian cancer via PTEN/PI3K/AKT pathway
The incidence rate of developing ovarian cancer decreases over the years; however, mortality ranks top among malignancies ...
Exploring transient global transcriptional changes induced by ascorbic acid revealed via atKAS-seq profiling
Exploring transient global transcriptional changes induced by ascorbic acid revealed via atKAS-seq profiling
Transcription initiates the formation of single-stranded DNA (ssDNA) regions within the genome, delineating transcription ...
ASAPA: a bioinformatic pipeline based on Iso-Seq that identifies the links among alternative splicing, alternative transcription initiation and alternative polyadenylation
ASAPA: a bioinformatic pipeline based on Iso-Seq that identifies the links among alternative splicing, alternative transcription initiation and alternative polyadenylation
Background: Although the events associated with alternative splicing (AS), alternative polyadenylation (APA) and alternati...
TRIM5 as a promising diagnostic biomarker of hepatocellular carcinoma: integrated analysis and experimental validation
TRIM5 as a promising diagnostic biomarker of hepatocellular carcinoma: integrated analysis and experimental validation
The TRIM family is associated with the membrane, and its involvement in the progression, growth, and development of variou...
Comparative and phylogenetic analysis of the complete chloroplast genomes of ten Pittosporum species from East Asia
Comparative and phylogenetic analysis of the complete chloroplast genomes of ten Pittosporum species from East Asia
Pittosporum (Pittosporaceae) is famous as the ornamental and medical values, which is distributed tropical and subtropical...
Knockout of lws1 in zebrafish (Danio rerio) reveals its role in regulating feeding and vision-guided behavior
Knockout of lws1 in zebrafish (Danio rerio) reveals its role in regulating feeding and vision-guided behavior
Long-wave sensitive (LWS) is a G protein-coupled receptor expressed in the retina, and zebrafish is a better model organis...
CRISPR du-HITI an attractive approach to targeting Long Noncoding RNA HCP5 as inhibitory factor for proliferation of ovarian cancer cell
CRISPR du-HITI an attractive approach to targeting Long Noncoding RNA HCP5 as inhibitory factor for proliferation of ovarian cancer cell
This research provides a glimmer of hope that the knockout of HCP5 leads to a therapy response to considerably prolong the...
Effect of gibberellin on crown root development in the mutant of the rice plasmodesmal Germin-like protein OsGER4
Effect of gibberellin on crown root development in the mutant of the rice plasmodesmal Germin-like protein OsGER4
Rice is an essential but highly stress-susceptible crop, whose root system plays an important role in plant development an...
Comprehensive pan-cancer analysis reveals SIRT5 is a predictive biomarker for prognosis and immunotherapy response
Comprehensive pan-cancer analysis reveals SIRT5 is a predictive biomarker for prognosis and immunotherapy response
Sirtuin 5 (SIRT5) is a promising therapeutic target involved in regulating multiple metabolic pathways in cells and organi...
Nuclear protein NOP2 serves as a poor-prognosis predictor of LUAD and aggravates the malignancy of lung adenocarcinoma cells
Nuclear protein NOP2 serves as a poor-prognosis predictor of LUAD and aggravates the malignancy of lung adenocarcinoma cells
Recent studies have shown that NOP2, a nucleolar protein, is up-regulated in various cancers, suggesting a potential link ...
CRISPR/Cas9-mediated mutagenesis of phytoene desaturase in pigeonpea and groundnut
CRISPR/Cas9-mediated mutagenesis of phytoene desaturase in pigeonpea and groundnut
The CRISPR/Cas9 technology, renowned for its ability to induce precise genetic alterations in various crop species, has en...
Identification of RNA methylation-related lncRNAs for prognostic assessment and immunotherapy in bladder cancer—based on single cell/Bulk RNA sequencing data
Identification of RNA methylation-related lncRNAs for prognostic assessment and immunotherapy in bladder cancer—based on single cell/Bulk RNA sequencing data
Bladder cancer is a malignancy characterized by significant heterogeneity. RNA methylation has received an increasing amou...
MiR-29a-3p mediates phosphatase and tensin homolog and inhibits osteoarthritis progression
MiR-29a-3p mediates phosphatase and tensin homolog and inhibits osteoarthritis progression
Despite substantial progress in clinical trials of osteoarthritis (OA) gene therapy, the prevalence of OA is still on the ...
Huang Qin decoction increases SLC6A4 expression and blocks the NFκB-mediated NLRP3/Caspase1/GSDMD pathway to disrupt colitis-associated carcinogenesis
Huang Qin decoction increases SLC6A4 expression and blocks the NFκB-mediated NLRP3/Caspase1/GSDMD pathway to disrupt colitis-associated carcinogenesis
Huang Qin decoction (HQD) is a traditional Chinese medicine formula for treating colitis, but the effects and molecular me...
ZNF692 drives malignant development of hepatocellular carcinoma cells by promoting ALDOA-dependent glycolysis
ZNF692 drives malignant development of hepatocellular carcinoma cells by promoting ALDOA-dependent glycolysis
Hepatocellular carcinoma (HCC) is one of the malignancies with the worst prognosis worldwide, in the occurrence and develo...
Exploring the potential biological function of GRK2 in colorectal cancer
Exploring the potential biological function of GRK2 in colorectal cancer
Colorectal cancer (CRC) is a malignant tumor of the gastrointestinal tract with high morbidity and mortality. There is gro...
Long non-coding RNA CCAT1 acts as an oncogene to promote radiation resistance in lung adenocarcinoma: an epigenomics-based investigation
Long non-coding RNA CCAT1 acts as an oncogene to promote radiation resistance in lung adenocarcinoma: an epigenomics-based investigation
Long non-coding RNAs (lncRNAs) appear to be the crucial modulators in various processes and critically influence the oncog...
Downregulation of lncRNA CDKN2B-AS1 attenuates inflammatory response in mice with allergic rhinitis by regulating miR-98-5p/SOCS1 axis
Downregulation of lncRNA CDKN2B-AS1 attenuates inflammatory response in mice with allergic rhinitis by regulating miR-98-5p/SOCS1 axis
Long non-coding RNA cyclin-dependent kinase inhibitor 2B antisense RNA 1 (CDKN2B-AS1) in various diseases has been verifie...
LINC02086 inhibits ferroptosis and promotes malignant phenotypes of pancreatic cancer via miR-342-3p/CA9 axis
LINC02086 inhibits ferroptosis and promotes malignant phenotypes of pancreatic cancer via miR-342-3p/CA9 axis
Long noncoding RNAs (lncRNAs) play important roles in modulating the tumorigenesis and progression of malignant tumors. LI...
CRISPR/Cas genome editing in plants: mechanisms, applications, and overcoming bottlenecks
CRISPR/Cas genome editing in plants: mechanisms, applications, and overcoming bottlenecks
The CRISPR/Cas systems have emerged as transformative tools for precisely manipulating plant genomes and enhancement. It h...
Codon usage bias and phylogenetic analysis of chloroplast genome in 36 gracilariaceae species
Codon usage bias and phylogenetic analysis of chloroplast genome in 36 gracilariaceae species
Gracilariaceae is a group of marine large red algae and main source of agar with important economic and ecological value. ...
Draft genome of novel cyanobacteria Sphaerothrix Gracilis isolated from coastal microplastics reveal insights to chemical ecology, bloom and plastic-utilization potential
Draft genome of novel cyanobacteria Sphaerothrix Gracilis isolated from coastal microplastics reveal insights to chemical ecology, bloom and plastic-utilization potential
Cyanobacteria are oxygenic photosynthetic organisms which are found across many ecosystems, including freshwater and marin...
Genome-wide identification and comparative analysis of the Amino Acid Transporter (AAT) gene family and their roles during Phaseolus vulgaris symbioses
Genome-wide identification and comparative analysis of the Amino Acid Transporter (AAT) gene family and their roles during Phaseolus vulgaris symbioses
Amino acid transporters (AATs) are essential integral membrane proteins that serve multiple roles, such as facilitating th...
Harnessing the potential of mutation breeding, CRISPR genome editing, and beyond for sustainable agriculture
Harnessing the potential of mutation breeding, CRISPR genome editing, and beyond for sustainable agriculture
By 2050, the global population is projected to exceed 9.5 billion, posing a formidable challenge to ensure food security w...
De novo transcriptome assembly and global analysis of differential gene expression of aphid tolerant wild mustard Rorippa indica (L.) Hiern infested by mustard aphid Lipaphis Erysimi (L.) Kaltenbach
De novo transcriptome assembly and global analysis of differential gene expression of aphid tolerant wild mustard Rorippa indica (L.) Hiern infested by mustard aphid Lipaphis Erysimi (L.) Kaltenbach
Rapeseed-mustard, the oleiferous Brassica species are important oilseed crops cultivated all over the globe. Mustard aphid...
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