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Role of long non-coding RNAs and natural products in prostate cancer: insights into key signaling pathways
Role of long non-coding RNAs and natural products in prostate cancer: insights into key signaling pathways
Prostate cancer (PC) ranks among the most prevalent cancers in males. Recent studies have highlighted intricate connection...
Prioritization of candidate genes regulating the dwarfness in rice by integration of whole-genome and transcriptome analyses
Prioritization of candidate genes regulating the dwarfness in rice by integration of whole-genome and transcriptome analyses
Dwarfism is a major trait for developing lodging-resistant rice cultivars. Gamma irradiation-induced mutagenesis has prove...
Genomics-assisted stacking of waxy1, opaque2, and crtRB1 genes for enhancing amylopectin in biofortified maize for industrial utilization and nutritional security
Genomics-assisted stacking of waxy1, opaque2, and crtRB1 genes for enhancing amylopectin in biofortified maize for industrial utilization and nutritional security
Waxy maize is highly preferred diet in developing countries due to its high amylopectin content. Enriching amylopectin in ...
Comparison of the rhizospheric soil bacteriomes of Oryza sativa and Solanum melongena crop cultivars reveals key genes and pathways involved in biosynthesis of ectoine, lysine, and catechol meta-cleavage
Comparison of the rhizospheric soil bacteriomes of Oryza sativa and Solanum melongena crop cultivars reveals key genes and pathways involved in biosynthesis of ectoine, lysine, and catechol meta-cleavage
Rice (Oryza sativa L.), Poaceae family, forms staple diet of half of world’s population, and brinjal (Solanum melong...
Overexpression of FTO alleviates traumatic brain injury induced posttraumatic epilepsy by upregulating NR4A2 expression via m6A demethylation
Overexpression of FTO alleviates traumatic brain injury induced posttraumatic epilepsy by upregulating NR4A2 expression via m6A demethylation
Post-traumatic epilepsy (PTE) is a debilitating chronic outcome of traumatic brain injury (TBI). Although FTO has been rep...
Elucidating circRNA-miRNA-mRNA competing endogenous regulatory RNA network during leaf rust pathogenesis in wheat (Triticum aestivum L.)
Elucidating circRNA-miRNA-mRNA competing endogenous regulatory RNA network during leaf rust pathogenesis in wheat (Triticum aestivum L.)
Advancements in bioinformatic tools and breakthroughs in high throughput RNA sequencing have unveiled the potential role o...
Narciclasine attenuates sepsis-associated acute kidney injury through the ESR1/S100A11 axis
Narciclasine attenuates sepsis-associated acute kidney injury through the ESR1/S100A11 axis
Narciclasine (Ncs) was effective in sepsis management due to its antioxidant properties. The present study dissected the p...
Pan-cancer secreted proteome and skeletal muscle regulation: insight from a proteogenomic data-driven knowledge base
Pan-cancer secreted proteome and skeletal muscle regulation: insight from a proteogenomic data-driven knowledge base
Large-scale, pan-cancer analysis is enabled by data driven knowledge bases that link tumor molecular profiles with phenoty...
Transcription factor MAZ activates the transcription of hypomethylated TYMP in ccRCC
Transcription factor MAZ activates the transcription of hypomethylated TYMP in ccRCC
Clear cell renal cell carcinoma (ccRCC) is a highly malignant tumor characterized by a significant prope...
Unraveling the potential mechanism and prognostic value of pentose phosphate pathway in hepatocellular carcinoma: a comprehensive analysis integrating bulk transcriptomics and single-cell sequencing data
Unraveling the potential mechanism and prognostic value of pentose phosphate pathway in hepatocellular carcinoma: a comprehensive analysis integrating bulk transcriptomics and single-cell sequencing data
Hepatocellular carcinoma (HCC) remains a malignant and life-threatening tumor with an extremely poor prognosis, posing a s...
Impact of structural variations and genome partitioning on bread wheat hybrid performance
Impact of structural variations and genome partitioning on bread wheat hybrid performance
The agronomical interest of hybrid wheat has long been a matter of debate. Compared to maize where hybrids have been succe...
pmiRScan: a LightGBM based method for prediction of animal pre-miRNAs
pmiRScan: a LightGBM based method for prediction of animal pre-miRNAs
MicroRNAs (miRNA) are categorized as short endogenous non-coding RNAs, which have a significant role in post-transcription...
A cutting-edge investigation of the multifaceted role of SOX family genes in cancer pathogenesis through the modulation of various signaling pathways
A cutting-edge investigation of the multifaceted role of SOX family genes in cancer pathogenesis through the modulation of various signaling pathways
This detailed study examines the complex role of the SOX family in various tumorigenic contexts, offering insights into ho...
Epigenetic modification mediated by PHF20/METTL14/HOXA13 signaling axis modulates osteogenic differentiation of mesenchymal stem cells
Epigenetic modification mediated by PHF20/METTL14/HOXA13 signaling axis modulates osteogenic differentiation of mesenchymal stem cells
This study investigates the mechanism of PHF20 in osteogenic differentiation of bone marrow mesenchymal stem cells (BMSCs)...
Application of a high-throughput swarm-based deep neural network Algorithm reveals SPAG5 downregulation as a potential therapeutic target in adult AML
Application of a high-throughput swarm-based deep neural network Algorithm reveals SPAG5 downregulation as a potential therapeutic target in adult AML
Gene‒gene interactions play pivotal roles in disease pathogenesis and are fundamental in the development of targeted...
Towards assembling functional cyanobacterial β-carboxysomes in Oryza sativa chloroplasts
Towards assembling functional cyanobacterial β-carboxysomes in Oryza sativa chloroplasts
The major limiting factor of photosynthesis in C3 plants is the enzyme, rubisco which inadequately distinguishes between c...
Circular RNAs in the pathogenesis of SARS-CoV-2: potential diagnostic biomarkers and therapeutic targets
Circular RNAs in the pathogenesis of SARS-CoV-2: potential diagnostic biomarkers and therapeutic targets
Since December 2019, the global dissemination of a novel coronavirus has precipitated a notable public health crisis, prom...
Unraveling the organellar genomic landscape of the therapeutic and entheogenic plant Mimosa tenuiflora: insights into genetic, structural, and evolutionary dynamics
Unraveling the organellar genomic landscape of the therapeutic and entheogenic plant Mimosa tenuiflora: insights into genetic, structural, and evolutionary dynamics
Mimosa tenuiflora, popularly known as “Jurema-Preta”, is a perennial tree or shrub native to the tropical regi...
Barley stripe mosaic virus-induced gene silencing for functional validation of abiotic stress in barley
Barley stripe mosaic virus-induced gene silencing for functional validation of abiotic stress in barley
The barley stripe mosaic virus (BSMV) uses its genomic RNA components (alpha, beta, and gamma) as an efficient method for ...
Xuanhong Dingchuan Tang suppresses bronchial asthma inflammation via the microRNA-107-3p/PTGS2/MAPK axis
Xuanhong Dingchuan Tang suppresses bronchial asthma inflammation via the microRNA-107-3p/PTGS2/MAPK axis
This study aimed to investigate the mechanism of Xuanhong Dingchuan Tang (XHDCT) in delaying bronchial asthma inflammation...
Integration of osimertinib-targeted EGFR gene-associated differential gene expression in constructing a prognostic model for lung adenocarcinoma
Integration of osimertinib-targeted EGFR gene-associated differential gene expression in constructing a prognostic model for lung adenocarcinoma
Lung adenocarcinoma (LUAD) is one of the deadliest cancers. Epidermal growth factor receptor-tyrosine kinase inhibitor (EG...
Serine related gene CCT6A promotes metastasis of hepatocellular carcinoma via interacting with RPS3
Serine related gene CCT6A promotes metastasis of hepatocellular carcinoma via interacting with RPS3
Metastasis is responsible for approximately 90% of lethality from solid tumors. Metabolic abnormalities are one of the key...
Gene clusters-based pathway enrichment analysis identifies four pan-cancer subtypes with distinct molecular and clinical features
Gene clusters-based pathway enrichment analysis identifies four pan-cancer subtypes with distinct molecular and clinical features
Pathways-based clustering methods have been proposed to explore tumor heterogeneity. However, such methods are currently d...
Decoding the role of durum wheat ascorbate peroxidase TdAPX7B-2 in abiotic stress response
Decoding the role of durum wheat ascorbate peroxidase TdAPX7B-2 in abiotic stress response
APX proteins are H2O2-scavenging enzymes induced during oxidative stress. In the first part of this study, we provided an ...
TBP activates DCBLD1 transcription to promote cell cycle progression in cervical cancer
TBP activates DCBLD1 transcription to promote cell cycle progression in cervical cancer
Discoidin, CUB, and LCCL domain-containing (DCBLD) proteins have been associated with poor prognosis of human cancers. Thi...
Tracing the intraspecies expansion of glyoxalase genes and their expanding roles across the genus Oryza
Tracing the intraspecies expansion of glyoxalase genes and their expanding roles across the genus Oryza
The genus Oryza is of utmost importance to human civilization as two of its species became agronomically productive and wi...
Transcriptome-wide investigation and functional characterization reveal a terpene synthase involved in γ-terpinene biosynthesis in Monarda citriodora
Transcriptome-wide investigation and functional characterization reveal a terpene synthase involved in γ-terpinene biosynthesis in Monarda citriodora
Monarda citriodora Cerv. ex Lag. is a rich source of industrially important compounds like γ-terpinene, carvacrol, th...
The role of disulfidptosis-associated LncRNA-LINC01137 in Osteosarcoma Biology and its regulatory effects on macrophage polarization
The role of disulfidptosis-associated LncRNA-LINC01137 in Osteosarcoma Biology and its regulatory effects on macrophage polarization
The objective of this research is to investigate the function of long non-coding RNA (lncRNA) associated with disulfidptos...
Breaking the yield-quality tradeoff: OsNLP3 in rice
Breaking the yield-quality tradeoff: OsNLP3 in rice
A recent study by Sun et al. OsNLP3 enhances grain weight and reduces grain chalkiness in rice sheds new insight on the cr...
Can nanotechnology and genomics innovations trigger agricultural revolution and sustainable development?
Can nanotechnology and genomics innovations trigger agricultural revolution and sustainable development?
At the dawn of new millennium, policy makers and researchers focused on sustainable agricultural growth, aiming for food s...
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