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Evolution of phenylalanine ammonia-lyase protein family from algae to angiosperm
Evolution of phenylalanine ammonia-lyase protein family from algae to angiosperm
Phenylpropanes, the precursors of various phenolic compounds in plants, are widely distributed. Phenylalanine ammonia-lyas...
A curated tissue-specific proteome, phosphoproteome, and kinome map of Drosophila melanogaster with an integrated outlook in circadian physiology
A curated tissue-specific proteome, phosphoproteome, and kinome map of Drosophila melanogaster with an integrated outlook in circadian physiology
The fruit fly Drosophila melanogaster is a simple multicellular model system widely used in biomedical research. Here, we ...
NSUN7 promotes cervical cancer progression through activation of ErbB signaling pathway
NSUN7 promotes cervical cancer progression through activation of ErbB signaling pathway
We aimed to investigate the role of NSUN7 in the progression of Cervical Cancer through a combination of bioinfor...
Deciphering nutrient stress in plants: integrative insight from metabolomics and proteomics
Deciphering nutrient stress in plants: integrative insight from metabolomics and proteomics
To comprehend the responses and resilience of plants under unfavorable environmental conditions, it is crucial to study th...
TFAP2A-regulated CRNDE enhances colon cancer progression and chemoresistance via RIPK3 interaction
TFAP2A-regulated CRNDE enhances colon cancer progression and chemoresistance via RIPK3 interaction
Colon cancer (CC) is a common malignancy with rising incidence worldwide. Despite advances in treatment strategies, many p...
Unraveling key genes and pathways involved in Verticillium wilt resistance by integrative GWAS and transcriptomic approaches in Upland cotton
Unraveling key genes and pathways involved in Verticillium wilt resistance by integrative GWAS and transcriptomic approaches in Upland cotton
Verticillium dahliae Kleb, the cause of Verticillium wilt, is a particularly destructive soil-borne vascular disease that ...
Characterization of 4-coumarate CoA ligase (4CL) gene family and functional study of Sm4CL2/3/7/9 in Salvia miltiorrhiza
Characterization of 4-coumarate CoA ligase (4CL) gene family and functional study of Sm4CL2/3/7/9 in Salvia miltiorrhiza
The 4-coumarate CoA ligase (4CL, EC6.2.1.12) enzyme is pivotal for the final step of three shared stages in the general ph...
Comprehensive insights and In silico analysis into the emerging role of LincRNAs in lung diseases pathogenesis; a step toward ncRNA precision
Comprehensive insights and In silico analysis into the emerging role of LincRNAs in lung diseases pathogenesis; a step toward ncRNA precision
Long non-coding RNAs (lncRNAs) have emerged as essential regulators of gene expression, significantly influencing various ...
miRNAs and their multifaceted role in cutaneous wound healing
miRNAs and their multifaceted role in cutaneous wound healing
The dynamic, complex process of cutaneous wound healing is required to restore skin integrity following an injury. This in...
Advancing vegetable genetics with gene editing: a pathway to food security and nutritional resilience in climate-shifted environments
Advancing vegetable genetics with gene editing: a pathway to food security and nutritional resilience in climate-shifted environments
As global populations grow and climate change increasingly disrupts agricultural systems, ensuring food security and nutri...
The role of exosomal non-coding RNAs in the breast cancer tumor microenvironment
The role of exosomal non-coding RNAs in the breast cancer tumor microenvironment
The leading form of cancer affecting females globally is breast cancer, characterized by an unregulated growth of cells wi...
Gonadal miRNomes and transcriptomes in infected fish reveal sexually dimorphic patterns of the immune response
Gonadal miRNomes and transcriptomes in infected fish reveal sexually dimorphic patterns of the immune response
Fish disease outbreaks caused by bacterial burdens are responsible for decreasing productivity in aquaculture. Unraveling ...
From fatty liver to fibrosis: the impact of miRNAs on NAFLD and NASH
From fatty liver to fibrosis: the impact of miRNAs on NAFLD and NASH
Non-alcoholic fatty liver disease (NAFLD) is a disease with various levels varying from fatty liver steatosis to acute ste...
Leptin drives glucose metabolism to promote cardiac protection via OPA1-mediated HDAC5 translocation and Glut4 transcription
Leptin drives glucose metabolism to promote cardiac protection via OPA1-mediated HDAC5 translocation and Glut4 transcription
Metabolic reprogramming, the shifting from fatty acid oxidation to glucose utilization, improves cardiac function as heart...
Transforming tomatoes into GABA-rich functional foods through genome editing: A modern biotechnological approach
Transforming tomatoes into GABA-rich functional foods through genome editing: A modern biotechnological approach
Gamma-aminobutyric acid (GABA) functions as an inhibitory neurotransmitter which blocks the impulses between nerve cells i...
The role of nanoparticles in transforming plant genetic engineering: advancements, challenges and future prospects
The role of nanoparticles in transforming plant genetic engineering: advancements, challenges and future prospects
Despite years of progress in biotechnology, altering the genetic makeup of many plant species, especially their plastids, ...
Mitochondria and its epigenetic dynamics: Insight into synaptic regulation and synaptopathies
Mitochondria and its epigenetic dynamics: Insight into synaptic regulation and synaptopathies
Mitochondria, the cellular powerhouses, are pivotal to neuronal function and health, particularly through their role in re...
Heterogeneity analysis and prognostic model construction of HPV negative oral squamous cell carcinoma T cells using ScRNA-seq and bulk-RNA analysis
Heterogeneity analysis and prognostic model construction of HPV negative oral squamous cell carcinoma T cells using ScRNA-seq and bulk-RNA analysis
T cells are involved in every stage of tumor development and significantly influence the tumor microenvironment (TME). Our...
SUMMER: an integrated nanopore sequencing pipeline for variants detection and clinical annotation on the human genome
SUMMER: an integrated nanopore sequencing pipeline for variants detection and clinical annotation on the human genome
Long-read sequencing has emerged as a transformative technology in recent years, offering significant potential for the mo...
High-throughput sequencing: a breakthrough in molecular diagnosis for precision medicine
High-throughput sequencing: a breakthrough in molecular diagnosis for precision medicine
High-resolution insights into the nucleotide arrangement within an organism’s genome are pivotal for deciphering its...
The interactive role of microRNA and other non-coding RNA in hepatitis B (HBV) associated fibrogenesis
The interactive role of microRNA and other non-coding RNA in hepatitis B (HBV) associated fibrogenesis
One of the outstanding features of chronic hepatitis B infection (CHB) is its strong association with liver fibrosis. CHB ...
Role of long non-coding RNAs and natural products in prostate cancer: insights into key signaling pathways
Role of long non-coding RNAs and natural products in prostate cancer: insights into key signaling pathways
Prostate cancer (PC) ranks among the most prevalent cancers in males. Recent studies have highlighted intricate connection...
Prioritization of candidate genes regulating the dwarfness in rice by integration of whole-genome and transcriptome analyses
Prioritization of candidate genes regulating the dwarfness in rice by integration of whole-genome and transcriptome analyses
Dwarfism is a major trait for developing lodging-resistant rice cultivars. Gamma irradiation-induced mutagenesis has prove...
Genomics-assisted stacking of waxy1, opaque2, and crtRB1 genes for enhancing amylopectin in biofortified maize for industrial utilization and nutritional security
Genomics-assisted stacking of waxy1, opaque2, and crtRB1 genes for enhancing amylopectin in biofortified maize for industrial utilization and nutritional security
Waxy maize is highly preferred diet in developing countries due to its high amylopectin content. Enriching amylopectin in ...
Comparison of the rhizospheric soil bacteriomes of Oryza sativa and Solanum melongena crop cultivars reveals key genes and pathways involved in biosynthesis of ectoine, lysine, and catechol meta-cleavage
Comparison of the rhizospheric soil bacteriomes of Oryza sativa and Solanum melongena crop cultivars reveals key genes and pathways involved in biosynthesis of ectoine, lysine, and catechol meta-cleavage
Rice (Oryza sativa L.), Poaceae family, forms staple diet of half of world’s population, and brinjal (Solanum melong...
Overexpression of FTO alleviates traumatic brain injury induced posttraumatic epilepsy by upregulating NR4A2 expression via m6A demethylation
Overexpression of FTO alleviates traumatic brain injury induced posttraumatic epilepsy by upregulating NR4A2 expression via m6A demethylation
Post-traumatic epilepsy (PTE) is a debilitating chronic outcome of traumatic brain injury (TBI). Although FTO has been rep...
Elucidating circRNA-miRNA-mRNA competing endogenous regulatory RNA network during leaf rust pathogenesis in wheat (Triticum aestivum L.)
Elucidating circRNA-miRNA-mRNA competing endogenous regulatory RNA network during leaf rust pathogenesis in wheat (Triticum aestivum L.)
Advancements in bioinformatic tools and breakthroughs in high throughput RNA sequencing have unveiled the potential role o...
Narciclasine attenuates sepsis-associated acute kidney injury through the ESR1/S100A11 axis
Narciclasine attenuates sepsis-associated acute kidney injury through the ESR1/S100A11 axis
Narciclasine (Ncs) was effective in sepsis management due to its antioxidant properties. The present study dissected the p...
Pan-cancer secreted proteome and skeletal muscle regulation: insight from a proteogenomic data-driven knowledge base
Pan-cancer secreted proteome and skeletal muscle regulation: insight from a proteogenomic data-driven knowledge base
Large-scale, pan-cancer analysis is enabled by data driven knowledge bases that link tumor molecular profiles with phenoty...
Transcription factor MAZ activates the transcription of hypomethylated TYMP in ccRCC
Transcription factor MAZ activates the transcription of hypomethylated TYMP in ccRCC
Clear cell renal cell carcinoma (ccRCC) is a highly malignant tumor characterized by a significant prope...
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