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Results from a multicenter, randomized, double‐blind, placebo‐controlled study of repository corticotropin injection for multiple sclerosis relapse that did not adequately respond to corticosteroids
Results from a multicenter, randomized, double‐blind, placebo‐controlled study of repository corticotropin injection for multiple sclerosis relapse that did not adequately respond to corticosteroids
Abstract Introduction About 20%–35% of multiple sclerosis (MS) patients fail to respond to high-dose corticosteroid...
Asymmetric distribution of enlarged perivascular spaces in centrum semiovale may be associated with epilepsy after acute ischemic stroke
Asymmetric distribution of enlarged perivascular spaces in centrum semiovale may be associated with epilepsy after acute ischemic stroke
Abstract Objective To investigate the factors influencing enlarged perivascular space (EPVS) characteristics at the onset ...
Effect of axitinib regulating the pathological blood–brain barrier functional recovery for glioblastoma therapeutics
Effect of axitinib regulating the pathological blood–brain barrier functional recovery for glioblastoma therapeutics
Abstract Aims Dysfunction of the blood–brain barrier (BBB) is a prominent pathological feature of glioblastoma (GBM...
Glioblastoma multiforme with vertebral metastases: A case report
Glioblastoma multiforme with vertebral metastases: A case report
Glioblastoma multiforme (GBM) is the most aggressive and lethal form of brain cancer.1 The currently recommended treatment...
Modulation of the rat hippocampal‐cortex network and episodic‐like memory performance following entorhinal cortex stimulation
Modulation of the rat hippocampal‐cortex network and episodic‐like memory performance following entorhinal cortex stimulation
Abstract Aims Entorhinal cortex (EC) deep brain stimulation (DBS) has shown a memory enhancement effect. However, its brai...
Role of lipoic acid in multiple sclerosis
Role of lipoic acid in multiple sclerosis
Abstract Lipoic acid (LA) is an endogenous antioxidant that exists widely in nature. Supplementation with LA is a promisin...
Bradykinin‐mediated estrogen‐dependent depressor response by direct activation of female‐specific distribution of myelinated Ah‐type baroreceptor neurons in rats
Bradykinin‐mediated estrogen‐dependent depressor response by direct activation of female‐specific distribution of myelinated Ah‐type baroreceptor neurons in rats
Abstract Aim To understand the direct impact of bradykinin in autonomic control of circulation through baroreflex afferent...
Attenuated alpha–gamma coupling in emotional dual pathways with right‐Amygdala predicting ineffective antidepressant response
Attenuated alpha–gamma coupling in emotional dual pathways with right‐Amygdala predicting ineffective antidepressant response
Abstract Aims The diversity of treatment outcomes for major depressive disorder (MDD) remains uncertain in neuropathology....
Clinical and imaging characteristics of 4H syndrome: A case report
Clinical and imaging characteristics of 4H syndrome: A case report
The term 4H syndrome was coined in 2006 and characterized by hypomyelination, hypodontia, and hypogonadotropic hypogonadis...
Microvascular decompression and aneurysm clipping for a patient with hemifacial spasm and ipsilateral labyrinthine artery aneurysm: A rare case report and literature review
Microvascular decompression and aneurysm clipping for a patient with hemifacial spasm and ipsilateral labyrinthine artery aneurysm: A rare case report and literature review
Preoperative MRI results showed a vascular anomaly at the REZ of the left facial nerve (Figure A) and an anomaly at the in...
Identifying epilepsy based on machine‐learning technique with diffusion kurtosis tensor
Identifying epilepsy based on machine‐learning technique with diffusion kurtosis tensor
Abstract Introduction Epilepsy is a serious hazard to human health. Minimally invasive surgery is an extremely effective t...
Development and validation of prediction models for neurocognitive disorders in adult patients admitted to the ICU with sleep disturbance
Development and validation of prediction models for neurocognitive disorders in adult patients admitted to the ICU with sleep disturbance
Abstract Background Neurocognitive disorders (NCDs) and sleep disturbance are highly prevalent in the perioperative period...
Electroacupuncture ameliorates postoperative cognitive dysfunction and associated neuroinflammation via NLRP3 signal inhibition in aged mice
Electroacupuncture ameliorates postoperative cognitive dysfunction and associated neuroinflammation via NLRP3 signal inhibition in aged mice
Abstract Background Postoperative cognitive dysfunction (POCD) is associated with worsened prognosis especially in aged po...
CELSR3 variants are associated with febrile seizures and epilepsy with antecedent febrile seizures
CELSR3 variants are associated with febrile seizures and epilepsy with antecedent febrile seizures
Abstract Aims To identify novel pathogenic gene of febrile seizures (FS)/epilepsy with antecedent FS (EFS+). Methods The t...
Retraction: Allopregnanolone restores the tyrosine hydroxylase‐positive neurons and motor performance in a 6‐OHDA‐injected mouse model
Retraction: Allopregnanolone restores the tyrosine hydroxylase‐positive neurons and motor performance in a 6‐OHDA‐injected mouse model
Retraction: Chen, Z-C, Wang, T-T, Bian, W, et al. Allopregnanolone restores the tyrosine hydroxylase-positive neurons and ...
BMPER alleviates ischemic brain injury by protecting neurons and inhibiting neuroinflammation via Smad3‐Akt‐Nrf2 pathway
BMPER alleviates ischemic brain injury by protecting neurons and inhibiting neuroinflammation via Smad3‐Akt‐Nrf2 pathway
Abstract Aims Bone morphogenetic proteins (BMPs) are a group of proteins related to bone morphogenesis. BMP-binding endoth...
Preoperative environment enrichment preserved neuroligin 1 expression possibly via epigenetic regulation to reduce postoperative cognitive dysfunction in mice
Preoperative environment enrichment preserved neuroligin 1 expression possibly via epigenetic regulation to reduce postoperative cognitive dysfunction in mice
Abstract Aims Postoperative cognitive dysfunction (POCD) is a common and significant syndrome. Our previous studies have s...
Ketogenic diet ameliorates cognitive impairment and neuroinflammation in a mouse model of Alzheimer’s disease
Ketogenic diet ameliorates cognitive impairment and neuroinflammation in a mouse model of Alzheimer’s disease
Abstract Introduction Alzheimer's disease (AD) is the most common neurodegenerative disorder that causes dementia and affe...
Impaired dynamic cerebral autoregulation is associated with the severity of neuroimaging features of cerebral small vessel disease
Impaired dynamic cerebral autoregulation is associated with the severity of neuroimaging features of cerebral small vessel disease
Abstract Aims Cerebral small vessel disease (CSVD) is characterized by functional and structural changes in small vessels....
SerpinA3N attenuates ischemic stroke injury by reducing apoptosis and neuroinflammation
SerpinA3N attenuates ischemic stroke injury by reducing apoptosis and neuroinflammation
Abstract Objective To assess the effect of serine protein inhibitor A3N (serpinA3N) in ischemic stroke and to explore its ...
Recent advances and perspectives of postoperative neurological disorders in the elderly surgical patients
Recent advances and perspectives of postoperative neurological disorders in the elderly surgical patients
Abstract Postoperative neurological disorders, including postoperative delirium (POD), postoperative cognitive dysfunction...
Kynurenic acid in neurodegenerative disorders—unique neuroprotection or double‐edged sword?
Kynurenic acid in neurodegenerative disorders—unique neuroprotection or double‐edged sword?
Abstract Aims The family of kynurenine pathway (KP) metabolites includes compounds produced along two arms of the path and...
Suppression of P2X3 receptor‐mediated currents by the activation of α2A‐adrenergic receptors in rat dorsal root ganglion neurons
Suppression of P2X3 receptor‐mediated currents by the activation of α2A‐adrenergic receptors in rat dorsal root ganglion neurons
Abstract Aims The α2-adrenergic receptor (α2-AR) agonists have been shown to be effective in the treatment of ...
Loss of long‐term benefit from VIM‐DBS in essential tremor: A secondary analysis of repeated measurements
Loss of long‐term benefit from VIM‐DBS in essential tremor: A secondary analysis of repeated measurements
Abstract Aims Deep brain stimulation (DBS) in the ventral intermediate nucleus (Vim-DBS) is the preferred surgical therapy...
Neuroimaging alterations in dementia with Lewy bodies and neuroimaging differences between dementia with Lewy bodies and Alzheimer's disease: An activation likelihood estimation meta‐analysis
Neuroimaging alterations in dementia with Lewy bodies and neuroimaging differences between dementia with Lewy bodies and Alzheimer's disease: An activation likelihood estimation meta‐analysis
Abstract Aims The aim of this study was to identify brain regions with local, structural, and functional abnormalities in ...
Brain stimulation: a therapeutic approach for the treatment of neurological disorders
Brain stimulation: a therapeutic approach for the treatment of neurological disorders
Abstract Brain stimulation has become one of the most acceptable therapeutic approaches in recent years and a powerful too...
Microglial deactivation by adeno‐associated virus expressing small‐hairpin GCH1 has protective effects against neuropathic pain development in a spinothalamic tract‐lesion model
Microglial deactivation by adeno‐associated virus expressing small‐hairpin GCH1 has protective effects against neuropathic pain development in a spinothalamic tract‐lesion model
Abstract Aims Neuropathic pain after spinal cord injury is one of the most difficult clinical problems after the loss of m...
18F‐fluorodeoxy‐glucose positron emission tomography pattern and prognostic predictors in patients with anti‐GABAB receptor encephalitis
18F‐fluorodeoxy‐glucose positron emission tomography pattern and prognostic predictors in patients with anti‐GABAB receptor encephalitis
Abstract Aims To identify the metabolic pattern and prognostic predictors in anti-gamma-aminobutyric-acid B (GABAB) recept...
Fisetin ameliorates cognitive impairment by activating mitophagy and suppressing neuroinflammation in rats with sepsis‐associated encephalopathy
Fisetin ameliorates cognitive impairment by activating mitophagy and suppressing neuroinflammation in rats with sepsis‐associated encephalopathy
Abstract Background Fisetin, the effective ingredient of the traditional Chinese medicine named Cotinus coggygria, is reco...
The role of hypoxia in stem cell regulation of the central nervous system: From embryonic development to adult proliferation
The role of hypoxia in stem cell regulation of the central nervous system: From embryonic development to adult proliferation
Abstract Hypoxia is involved in the regulation of various cell functions in the body, including the regulation of stem cel...
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