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The current landscape for diabetes treatment: Preventing diabetes-associated CV risk
The current landscape for diabetes treatment: Preventing diabetes-associated CV risk
Atherosclerosis is a progressive, chronic inflammatory disease with an immune component characterized by accumulation of l...
The Nutri-Score nutrition label: Associations between the underlying nutritional profile of foods and lipoprotein particle subclass profiles in adults
The Nutri-Score nutrition label: Associations between the underlying nutritional profile of foods and lipoprotein particle subclass profiles in adults
Available online 20 April 2024, 117559Author links open overlay panel, , , , Highlights•Lipoprotein particle size is assoc...
Remnant cholesterol, LDL cholesterol, and apoB absolute mass changes explain results of the PROMINENT trial.
Remnant cholesterol, LDL cholesterol, and apoB absolute mass changes explain results of the PROMINENT trial.
Available online 20 April 2024, 117556Author links open overlay panel, , Highlights•Absolute mass changes in remnant chole...
Modification of lipoprotein metabolism and function driving atherogenesis in diabetes
Modification of lipoprotein metabolism and function driving atherogenesis in diabetes
Available online 17 April 2024, 117545Author links open overlay panel, , Highlights•Type 2 diabetes mellitus (T2DM) is a c...
DEep LearnIng-based QuaNtification of Epicardial Adipose Tissue predicts MACE in patients undergoing stress CMR
DEep LearnIng-based QuaNtification of Epicardial Adipose Tissue predicts MACE in patients undergoing stress CMR
Stress cardiac magnetic resonance (CMR) is a powerful diagnostic tool with remarkable accuracy in identifying functionally...
From a dirty breath to atherosclerosis: Ozone pollution and neutrophil extracellular traps (NETs)
From a dirty breath to atherosclerosis: Ozone pollution and neutrophil extracellular traps (NETs)
Available online 18 April 2024, 117557Author links open overlay panel, Section snippetsAre Beijing authors‘ observations a...
Treatment patterns and adherence to lipid-lowering drugs during eight-year follow-up after a coronary heart disease event
Treatment patterns and adherence to lipid-lowering drugs during eight-year follow-up after a coronary heart disease event
Available online 15 April 2024, 117550Author links open overlay panel, , , , , , , Highlights:•Less than 70% of patients w...
Prognostic value of serum immunoglobulin M levels in patients with acute coronary syndrome
Prognostic value of serum immunoglobulin M levels in patients with acute coronary syndrome
Acute coronary syndromes (ACS) is defined as clinical syndromes characterized by acute myocardial ischemia, including unst...
An evaluation of the cost-effectiveness of population genetic screening for familial hypercholesterolemia in US patients
An evaluation of the cost-effectiveness of population genetic screening for familial hypercholesterolemia in US patients
In the United States, approximately 1 in every 212 people are affected by familial hypercholesterolemia (FH), a hereditary...
The LEPIS-HuR-TMOD4 axis regulates hepatic cholesterol homeostasis and accelerates atherosclerosis
The LEPIS-HuR-TMOD4 axis regulates hepatic cholesterol homeostasis and accelerates atherosclerosis
Available online 16 April 2024, 117554Author links open overlay panel, , , , , , , , Highlights•LEPIS promotes the occurre...
Adiposity, type 2 diabetes and atherosclerotic cardiovascular disease risk: Use and abuse of the body mass index
Adiposity, type 2 diabetes and atherosclerotic cardiovascular disease risk: Use and abuse of the body mass index
The prevalence of individuals with an elevated body weight has markedly increased since the 80’s, up to the point that a n...
Insulin resistance in the adipose tissue predicts future vascular resistance: The Hiroshima Study on Glucose Metabolism and Cardiovascular Diseases
Insulin resistance in the adipose tissue predicts future vascular resistance: The Hiroshima Study on Glucose Metabolism and Cardiovascular Diseases
Insulin resistance refers to reduced insulin response in the target tissues, including liver, skeletal muscle, and adipose...
Enhanced identification of familial hypercholesterolemia using central laboratory algorithms
Enhanced identification of familial hypercholesterolemia using central laboratory algorithms
Background and aimsFamilial hypercholesterolemia (FH) is a highly prevalent genetic disorder resulting in markedly elevate...
Dual pathway antithrombotic treatment and risk reduction in patients with atherosclerotic cardiovascular disease - a real-world perspective
Dual pathway antithrombotic treatment and risk reduction in patients with atherosclerotic cardiovascular disease - a real-world perspective
The persisting risk of cardiovascular disease (CVD) events despite reaching targets for known CVD risk factor such as low ...
Differential age-specific associations of LDL cholesterol and body mass index with coronary heart disease
Differential age-specific associations of LDL cholesterol and body mass index with coronary heart disease
Population aging leads to an increased incidence of coronary heart disease (CHD). Low‐density lipoprotein cholesterol (LDL...
Clinical practice recommendations on lipoprotein apheresis for children with homozygous familial hypercholesterolaemia: An expert consensus statement from ERKNet and ESPN
Clinical practice recommendations on lipoprotein apheresis for children with homozygous familial hypercholesterolaemia: An expert consensus statement from ERKNet and ESPN
Homozygous familial hypercholesterolaemia is a life-threatening genetic condition, which causes extremely elevated LDL-C l...
Ten-year mortality after treating obstructive coronary atherosclerosis with contemporary stents in patients with or without concomitant peripheral arterial disease
Ten-year mortality after treating obstructive coronary atherosclerosis with contemporary stents in patients with or without concomitant peripheral arterial disease
Background and aimsPrevious studies in percutaneous coronary intervention (PCI) patients showed a higher 3-year adverse ev...
l-thyroxine attenuates extracellular Hsp90α-induced vascular endothelial calcification in diabetes mellitus, as revealed by parallel metabolic profiles
l-thyroxine attenuates extracellular Hsp90α-induced vascular endothelial calcification in diabetes mellitus, as revealed by parallel metabolic profiles
Peripheral arterial disease (PAD) is the most common complication of type 2 diabetes mellitus (T2DM), occurring in approxi...
Inhibition of PCSK9 with evolocumab modulates lipoproteins and monocyte activation in high-risk ASCVD subjects
Inhibition of PCSK9 with evolocumab modulates lipoproteins and monocyte activation in high-risk ASCVD subjects
BackgroundMechanistic studies suggest that proprotein convertase subtilisin/kexin type 9 inhibitors can modulate inflammat...
Drug target Mendelian randomization supports apolipoprotein C3-lowering for lipoprotein-lipid levels reductions and cardiovascular diseases prevention
Drug target Mendelian randomization supports apolipoprotein C3-lowering for lipoprotein-lipid levels reductions and cardiovascular diseases prevention
Apolipoprotein C-III (apoC3) is an established target for triglyceride lowering. ApoC3 reduction by the antisense oligonuc...
A universal plasma metabolites-derived signature predicts cardiovascular disease risk in MAFLD
A universal plasma metabolites-derived signature predicts cardiovascular disease risk in MAFLD
Fatty liver has become the most prevalent chronic liver disease globally and it is strongly associated with an increased r...
Stromal cell-derived factor-1 alpha improves cardiac function in a novel diet-induced coronary atherosclerosis model, the SR-B1ΔCT/LDLR KO mouse
Stromal cell-derived factor-1 alpha improves cardiac function in a novel diet-induced coronary atherosclerosis model, the SR-B1ΔCT/LDLR KO mouse
Ischemic heart disease remains one of the leading causes of death [1,2]. It is most often caused by occlusive coronary art...
Association of cardiovascular health with subclinical coronary atherosclerosis progression among five racial and ethnic groups: The MASALA and MESA studies
Association of cardiovascular health with subclinical coronary atherosclerosis progression among five racial and ethnic groups: The MASALA and MESA studies
The American Heart Association (AHA) recommends that Americans adhere to the construct of ideal cardiovascular health (CVH...
Subclinical atherosclerosis in young adults predicting cardiovascular disease: The cardiovascular risk in young Finns study
Subclinical atherosclerosis in young adults predicting cardiovascular disease: The cardiovascular risk in young Finns study
Background and aimsAtherosclerosis is accompanied by pre-clinical vascular changes that can be detected using ultrasound i...
Heparanase promotes the onset and progression of atherosclerosis in apolipoprotein E gene knockout mice
Heparanase promotes the onset and progression of atherosclerosis in apolipoprotein E gene knockout mice
Atherosclerosis, a progressive chronic inflammatory disease of mid-sized to large arteries, is the major underlying cause ...
Peptide OM-LV20 promotes arteriogenesis induced by femoral artery ligature via the miR-29b-3p/VEGFA axis
Peptide OM-LV20 promotes arteriogenesis induced by femoral artery ligature via the miR-29b-3p/VEGFA axis
Under ischemic conditions, arteriogenesis (also known as the collateral vessel growth), which means the enlargement of pre...
Effect of combining evolocumab with statin on carotid intraplaque neovascularization in patients with premature coronary artery disease (EPOCH)
Effect of combining evolocumab with statin on carotid intraplaque neovascularization in patients with premature coronary artery disease (EPOCH)
Methods41 patients were included to receive treatments with biweekly evolocumab (n = 22) or placebo (n = 19) in addition t...
Improved lipid-lowering treatment and reduction in cardiovascular disease burden in homozygous familial hypercholesterolemia: The SAFEHEART follow-up study
Improved lipid-lowering treatment and reduction in cardiovascular disease burden in homozygous familial hypercholesterolemia: The SAFEHEART follow-up study
Homozygous familial hypercholesterolemia (HoFH) is a rare and severe genetic disease, caused by loss-of-function pathogeni...
Metabolic dysfunction-associated steatotic liver disease: An opportunity for collaboration between cardiology and hepatology
Metabolic dysfunction-associated steatotic liver disease: An opportunity for collaboration between cardiology and hepatology
Available online 16 March 2024, 117523Author links open overlay panel, , , , , , Highlights•At the core of fatty liver dis...
Applicability and impact of the COMPASS trial in a Canadian population of patients with atherosclerotic disease
Applicability and impact of the COMPASS trial in a Canadian population of patients with atherosclerotic disease
Background and aimsIn the COMPASS trial, low-dose rivaroxaban with aspirin improved cardiovascular outcomes in patients wi...
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