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Synthesis, preclinical assessment, and first-in-human study of [18F]d4-FET for brain tumor imaging
Synthesis, preclinical assessment, and first-in-human study of [18F]d4-FET for brain tumor imaging
Tumor-to-background ratio (TBR) is a critical metric in oncologic PET imaging. This study aims to enhance the TBR of [18F]...
Value of [18F]AlF-NOTA-FAPI-04 PET/CT for predicting pathological response and survival in patients with locally advanced pancreatic ductal adenocarcinoma receiving neoadjuvant chemotherapy
Value of [18F]AlF-NOTA-FAPI-04 PET/CT for predicting pathological response and survival in patients with locally advanced pancreatic ductal adenocarcinoma receiving neoadjuvant chemotherapy
This study aimed to evaluate the predictive value of [18F]AlF-NOTA-FAPI-04 PET/CT for pathological response to neoadjuvant...
First real-world clinical experience with [177Lu]Lu-PSMA-I&T in patients with metastatic castration-resistant prostate cancer beyond VISION and TheraP criteria
First real-world clinical experience with [177Lu]Lu-PSMA-I&T in patients with metastatic castration-resistant prostate cancer beyond VISION and TheraP criteria
To report real-world clinical experience with [177Lu]Lu-PSMA-I&T targeted radionuclide therapy (TRT) in patients w...
Can PSMA PET detect intratumour heterogeneity in histological PSMA expression of primary prostate cancer? Analysis of [68Ga]Ga-PSMA-11 and [18F]PSMA-1007
Can PSMA PET detect intratumour heterogeneity in histological PSMA expression of primary prostate cancer? Analysis of [68Ga]Ga-PSMA-11 and [18F]PSMA-1007
Prostate-specific membrane-antigen positron emission tomography (PSMA PET) is a promising candidate for non-invasive chara...
Clinical impact of an explainable machine learning with amino acid PET imaging: application to the diagnosis of aggressive glioma
Clinical impact of an explainable machine learning with amino acid PET imaging: application to the diagnosis of aggressive glioma
Radiomics-based machine learning (ML) models of amino acid positron emission tomography (PET) images have shown efficiency...
Lutetium-177 PSMA radioligand therapy in taxan-naive first- and second-line metastatic castration resistant prostate cancer after first-line ARPI therapy
Lutetium-177 PSMA radioligand therapy in taxan-naive first- and second-line metastatic castration resistant prostate cancer after first-line ARPI therapy
Lutetium-177 Prostate-specific membrane antigen (Lu-PSMA) radioligand therapy is EMA-approved for metastatic castration re...
Predictive and prognostic value of 18F-FES PET/CT for patients with recurrent or metastatic breast cancer treated with endocrine therapy plus cyclin-dependent kinase 4/6 inhibitors
Predictive and prognostic value of 18F-FES PET/CT for patients with recurrent or metastatic breast cancer treated with endocrine therapy plus cyclin-dependent kinase 4/6 inhibitors
Estrogen receptor (ER) expression and heterogeneity affect endocrine therapy efficacy. 18F-fluoroestradiol (18F-FES) PET/C...
PET radiomics for histologic subtype classification of non-small cell lung cancer: a systematic review and meta-analysis
PET radiomics for histologic subtype classification of non-small cell lung cancer: a systematic review and meta-analysis
To systematically review the literature and perform a meta-analysis of PET radiomics for histologic subtype classification...
Future direction: molecular imaging-based stem cell research
Future direction: molecular imaging-based stem cell research
Advances in imaging, especially molecular imaging modalities (e.g., positron emission tomography (PET), magnetic resonance...
Impact of Tafamidis on [99mTc]Tc-pyrophosphate Scintigraphy in Ala97Ser Hereditary Transthyretin amyloid cardiomyopathy: significant initial reduction with stable Long-Term effects
Impact of Tafamidis on [99mTc]Tc-pyrophosphate Scintigraphy in Ala97Ser Hereditary Transthyretin amyloid cardiomyopathy: significant initial reduction with stable Long-Term effects
Tafamidis has shown potential in slowing disease progression in patients with transthyretin amyloid cardiomyopathy (ATTR-C...
Trends in nanobody radiotheranostics
Trends in nanobody radiotheranostics
As the smallest antibody fragment with specific binding affinity, nanobody-based nuclear medicine has demonstrated signifi...
The molar dose of FAPI administered impacts on the FAP-targeted PET imaging and therapy in mouse syngeneic tumor models
The molar dose of FAPI administered impacts on the FAP-targeted PET imaging and therapy in mouse syngeneic tumor models
Since fibroblast activation protein (FAP), one predominant biomarker of cancer associated fibroblasts (CAFs), is highly ex...
Staging of prostate Cancer with ultra-fast PSMA-PET scans enhanced by AI
Staging of prostate Cancer with ultra-fast PSMA-PET scans enhanced by AI
PSMA-PET is a reference standard examination for patients with prostate cancer, but even using recently introduced digital...
Nuclear cardiology a solid pillar in the new chronic coronary syndromes ESC guidelines
Nuclear cardiology a solid pillar in the new chronic coronary syndromes ESC guidelines
The concept of chronic coronary syndromes (CCS) has been recently introduced [1]. Different from the traditional concept o...
FAPI PET for monitoring of rheumatological treatment in multifocal peritoneal nodular fibrosis: a case study
FAPI PET for monitoring of rheumatological treatment in multifocal peritoneal nodular fibrosis: a case study
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which...
[18F]F-FAPI-42 PET dynamic imaging characteristics and multiparametric quantification of lung cancer: an exploratory study using uEXPLORER PET/CT
[18F]F-FAPI-42 PET dynamic imaging characteristics and multiparametric quantification of lung cancer: an exploratory study using uEXPLORER PET/CT
To explore the dynamic and parametric characteristics of [18F]F-FAPI-42 PET/CT in lung cancers. Nineteen participants with...
Transcriptionally downregulated GABAergic genes associated with synaptic density network dysfunction in temporal lobe epilepsy
Transcriptionally downregulated GABAergic genes associated with synaptic density network dysfunction in temporal lobe epilepsy
Temporal lobe epilepsy (TLE) is a brain network disorder closely associated with synaptic loss and has a genetic basis. Ho...
[18F]FDG PET/CT for predicting neoadjuvant PD-L1 blockade monotherapy treatment response in patients with locally advanced esophageal squamous cell carcinoma: a preliminary study
[18F]FDG PET/CT for predicting neoadjuvant PD-L1 blockade monotherapy treatment response in patients with locally advanced esophageal squamous cell carcinoma: a preliminary study
To investigate the predictive value of 2-[18F]-fluoro-2-deoxy-D-glucose ([18F]FDG) PET/CT for evaluating primary tumor (PT...
Preclinical investigation of [149Tb]Tb-DOTATATE and [149Tb]Tb-DOTA-LM3 for tumor-targeted alpha therapy
Preclinical investigation of [149Tb]Tb-DOTATATE and [149Tb]Tb-DOTA-LM3 for tumor-targeted alpha therapy
Terbium-149 is a short-lived α-particle emitter, potentially useful for tumor-targeted therapy. The aim of this study...
Mapping the knowledge landscape of the PET/MR domain: a multidimensional bibliometric analysis
Mapping the knowledge landscape of the PET/MR domain: a multidimensional bibliometric analysis
This study aims to conduct a bibliometric analysis to explore research trends, collaboration patterns, and emerging themes...
JHU-2545 preferentially shields salivary glands and kidneys during PSMA-targeted imaging
JHU-2545 preferentially shields salivary glands and kidneys during PSMA-targeted imaging
Prostate-specific membrane antigen (PSMA) radioligand therapy is a promising treatment for metastatic castration-resistant...
Assessment of fully quantitative and simplified methods for analysis of [68Ga]Ga-FAPI-46 uptake in patients with pancreatobiliary cancer using LAFOV PET/CT
Assessment of fully quantitative and simplified methods for analysis of [68Ga]Ga-FAPI-46 uptake in patients with pancreatobiliary cancer using LAFOV PET/CT
The aim of this study was to validate simplified methods for quantifying [68Ga]Ga-FAPI-46 uptake against full pharmacokine...
Preliminary evaluation of a novel PSMA-targeting radiopharmaceutical [68Ga]Ga/[177Lu]Lu–NYM032 for theranostic use in prostate cancer
Preliminary evaluation of a novel PSMA-targeting radiopharmaceutical [68Ga]Ga/[177Lu]Lu–NYM032 for theranostic use in prostate cancer
A novel theranostic radiopharmaceutical targeting prostate-specific membrane antigen (PSMA), [68Ga]Ga/[177Lu]Lu–NYM0...
Molecular imaging: The bridge from human phenome to personalized precision medicine
Molecular imaging: The bridge from human phenome to personalized precision medicine
Venter JC, Adams MD, Myers EW, Li PW, Mural RJ, Sutton GG, et al. The sequence of the human genome. Science. 2001;291(5507...
Dual-energy x-ray absorptiometry (DXA) in practice: a clinical centre survey endorsed by the European Association of Nuclear Medicine (EANM)
Dual-energy x-ray absorptiometry (DXA) in practice: a clinical centre survey endorsed by the European Association of Nuclear Medicine (EANM)
The survey was mainly completed by physicians (52.6%); out of them, 31.6% were nuclear medicine physicians/radiologists, f...
PSMA-targeted radioligand therapy in metastatic prostate cancer: Comprehensive analysis of recent evidence
PSMA-targeted radioligand therapy in metastatic prostate cancer: Comprehensive analysis of recent evidence
The meta-analysis by Dai et al., which included 100 studies for a total of 8,711 patients (7,826 treated with [177Lu]Lu-PS...
Three-dimensional spatial localization and volume estimation of prostate tumors using 18F-PSMA-1007 PET/CT versus multiparametric MRI
Three-dimensional spatial localization and volume estimation of prostate tumors using 18F-PSMA-1007 PET/CT versus multiparametric MRI
Fluorine-18 prostate-specific membrane antigen-1007 positron emission tomography/computed tomography (18F-PSMA-10...
CD38-specific immunoPET imaging for multiple myeloma diagnosis and therapeutic monitoring: preclinical and first-in-human studies
CD38-specific immunoPET imaging for multiple myeloma diagnosis and therapeutic monitoring: preclinical and first-in-human studies
CD38 is a glycoprotein highly specific to multiple myeloma (MM). Therapeutics using antibodies targeting CD38 have shown p...
Efficient radiolabeling of mesoporous silica nanoparticles for single-cell PET imaging
Efficient radiolabeling of mesoporous silica nanoparticles for single-cell PET imaging
Nanoparticles are highly efficient vectors for ferrying contrast agents across cell membranes, enabling ultra-sensitive in...
Evaluation of long axial field-of-view (LAFOV) PET/CT for post-treatment dosimetry in Yttrium-90 radioembolization of liver tumors: a comparative study with conventional SPECT imaging
Evaluation of long axial field-of-view (LAFOV) PET/CT for post-treatment dosimetry in Yttrium-90 radioembolization of liver tumors: a comparative study with conventional SPECT imaging
Long axial field-of-view (LAFOV) positron emission tomography/computed tomography (PET/CT) scanners enable high sensitivit...
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