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Dopaminergic PET to SPECT domain adaptation: a cycle GAN translation approach
Dopaminergic PET to SPECT domain adaptation: a cycle GAN translation approach
Dopamine transporter imaging is routinely used in Parkinson’s disease (PD) and atypical parkinsonian syndromes (APS)...
Radioiodine-refractory thyroid cancer—is it time to change the definition in light of novel redifferentiation therapies?
Radioiodine-refractory thyroid cancer—is it time to change the definition in light of novel redifferentiation therapies?
A growing body of evidence from clinical studies of redifferentiation therapies supports redefining RAI-R DTC. These studi...
New horizons for the World Federation of Nuclear Medicine and Biology: achievements, partnerships, and future directions
New horizons for the World Federation of Nuclear Medicine and Biology: achievements, partnerships, and future directions
Expanding WFNMB membership is a key priority, particularly by making membership accessible to countries with small or unde...
Radioiodinated Nanobody immunoPET probe for in vivo detection of CD147 in pan-cancer
Radioiodinated Nanobody immunoPET probe for in vivo detection of CD147 in pan-cancer
To develop the extracellular matrix metalloproteinase inducer (CD147)-targeting therapeutic strategies, accurate detection...
Feasibility of PET-enabled dual-energy CT imaging: First physical phantom and initial patient study results
Feasibility of PET-enabled dual-energy CT imaging: First physical phantom and initial patient study results
Dual-energy (DE) CT enables material decomposition by using two different x-ray energies and may be combined with PET for ...
[18F]FAA-guided re-operative surgery for recurrent differentiated thyroid cancer
[18F]FAA-guided re-operative surgery for recurrent differentiated thyroid cancer
Ethics approval The current study was approved by the Institutional...
Synthesis and preclinical evaluation of [18F]AlF-NOTA-Asp2-PEG2-JR11 as a novel antagonist radioligand for PET imaging of somatostatin receptor
Synthesis and preclinical evaluation of [18F]AlF-NOTA-Asp2-PEG2-JR11 as a novel antagonist radioligand for PET imaging of somatostatin receptor
Somatostatin receptor (SSTR) antagonists have recently emerged as preferable radiotracers for SSTR-targeted imaging and th...
Pre-symptomatic scintigraphic and genetic cascade screening in cardiac transthyretin amyloidosis
Pre-symptomatic scintigraphic and genetic cascade screening in cardiac transthyretin amyloidosis
While early diagnosis is crucial, as new treatments can significantly slow the progression of the disease, there is growin...
Comparison of clinical performance between late and standard total-body [68 Ga]Ga-PSMA-11 in biochemical recurrent prostate cancer
Comparison of clinical performance between late and standard total-body [68 Ga]Ga-PSMA-11 in biochemical recurrent prostate cancer
Enhanced lesion detection in prostate cancer is observed with late [68 Ga]Ga-PSMA-11 PET/CT imaging compared to s...
Effect of molar dose on the in vivo tissue biodistribution profile of FAP-targeted radioligand therapeutics
Effect of molar dose on the in vivo tissue biodistribution profile of FAP-targeted radioligand therapeutics
177Lu-OncoFAP-23 is a novel FAP-targeted radioligand therapeutic (RLT) with high and prolonged tumor residence time and pr...
Towards the clinical translation of a silver sulfide nanoparticle contrast agent: large scale production with a highly parallelized microfluidic chip
Towards the clinical translation of a silver sulfide nanoparticle contrast agent: large scale production with a highly parallelized microfluidic chip
Ultrasmall silver sulfide nanoparticles (Ag2S-NP) have been identified as promising contrast agents for a number of modali...
EANM expert opinion: How can lessons from radiobiology be applied to the design of clinical trials? Part I: back to the basics of absorbed dose–response and threshold absorbed doses
EANM expert opinion: How can lessons from radiobiology be applied to the design of clinical trials? Part I: back to the basics of absorbed dose–response and threshold absorbed doses
This study by the EANM radiobiology working group aims to analyze the efficacy and toxicity of targeted radionuclide thera...
A head-to-head comparison of [68Ga]Ga-DOTA-FGFR1 and [18F]FDG PET/CT in the diagnosis of lung cancer
A head-to-head comparison of [68Ga]Ga-DOTA-FGFR1 and [18F]FDG PET/CT in the diagnosis of lung cancer
This study aimed to compare the diagnostic value of [68Ga]Ga-DOTA-FGFR1 and [18F]FDG PET/CT in the evaluation of lung canc...
Design, preclinical evaluation, and first-in-human PET study of [68Ga]Ga-PSFA-01: a PSMA/FAP heterobivalent tracer
Design, preclinical evaluation, and first-in-human PET study of [68Ga]Ga-PSFA-01: a PSMA/FAP heterobivalent tracer
Prostate cancer (PCa), characterized by tumor heterogeneity, may exhibit low or absent prostate-specific membrane antigen ...
Expert consensus on workflow of PET/CT with long axial field-of-view
Expert consensus on workflow of PET/CT with long axial field-of-view
Positron emission tomography/computed tomography (PET/CT) imaging has been widely used in clinical practice. Long axial fi...
[68Ga]Ga-FAPI-46 PET/CT as an early indicator of complete remission in a patient treated with pembrolizumab for stage IV NSCLC
[68Ga]Ga-FAPI-46 PET/CT as an early indicator of complete remission in a patient treated with pembrolizumab for stage IV NSCLC
Ethics approval and consent to participate The PROFILE study was pe...
Preoperative assessment of pancreatic cancer with [68Ga]Ga-DOTA-FAPI-04 PET/MR versus [18F]-FDG PET/CT plus contrast-enhanced CT: a prospective preliminary study
Preoperative assessment of pancreatic cancer with [68Ga]Ga-DOTA-FAPI-04 PET/MR versus [18F]-FDG PET/CT plus contrast-enhanced CT: a prospective preliminary study
To assess the diagnostic performance of [68Ga]Ga-DOTA-FAPI-04 PET/MR imaging in the preoperative evaluation of pancreatic ...
Smaller is better? Compact vs. Conventional gamma camera for sentinel lymph node localization in patients with breast cancer
Smaller is better? Compact vs. Conventional gamma camera for sentinel lymph node localization in patients with breast cancer
Sentinel lymph node biopsy (SLNB) has been recognized as “the gold standard” for axillary staging in early bre...
αvβ6-integrin targeted [68Ga]Ga-Trivehexin PET/CT imaging of a rare bronchial mucoepidermoid carcinoma
αvβ6-integrin targeted [68Ga]Ga-Trivehexin PET/CT imaging of a rare bronchial mucoepidermoid carcinoma
Conflict of interest The authors declare no competing interests. ...
Whole-body parametric mapping of tumour perfusion in metastatic prostate cancer using long axial field-of-view [15O]H2O PET
Whole-body parametric mapping of tumour perfusion in metastatic prostate cancer using long axial field-of-view [15O]H2O PET
Tumour perfusion is a nutrient-agnostic biomarker for cancer metabolic rate. Use of tumour perfusion for cancer growth ass...
Combined brain and spinal FDG PET in the differentiation between ALS and ALS mimics – correction and additional validation study
Combined brain and spinal FDG PET in the differentiation between ALS and ALS mimics – correction and additional validation study
Nuclear Medicine and Molecular Imaging, Department of Imaging and Pathology, KU Leuven, Leuven, 3000, BelgiumDonatienne Va...
Experience of rescue therapy with [177Lu]Lu-rhPSMA-10.1 in patients with primary or acquired resistance to [177Lu]Lu-PSMA-I&T
Experience of rescue therapy with [177Lu]Lu-rhPSMA-10.1 in patients with primary or acquired resistance to [177Lu]Lu-PSMA-I&T
Radioligand therapy is an increasingly important option for the treatment of metastatic castrate-resistant prostate cancer...
Diagnostic efficacy of [68Ga]Ga-NY104 PET/CT to identify clear cell renal cell carcinoma
Diagnostic efficacy of [68Ga]Ga-NY104 PET/CT to identify clear cell renal cell carcinoma
Most clear cell renal cell carcinoma (ccRCC) overexpresses carbonic anhydrase IX (CAIX). [68Ga]Ga-NY104 is a small-molecul...
Hepatobiliary scintigraphy in post-cholecystectomy patients: added value of morphological dynamic SPECT/CT
Hepatobiliary scintigraphy in post-cholecystectomy patients: added value of morphological dynamic SPECT/CT
Ethics approval N/A. ...
[68Ga]Ga-FAPI-04 PET/CT imaging of a patient with neurosyphilis mimicking intracranial malignant tumor
[68Ga]Ga-FAPI-04 PET/CT imaging of a patient with neurosyphilis mimicking intracranial malignant tumor
Informed consent and ethical approval This study was approv...
Efficient characterization of multiple binding sites of small molecule imaging ligands on amyloid-beta, tau and alpha-synuclein
Efficient characterization of multiple binding sites of small molecule imaging ligands on amyloid-beta, tau and alpha-synuclein
There is an unmet need for compounds to detect fibrillar forms of alpha-synuclein (αSyn) and 4-repeat tau, which are ...
Sex differences in coronary atherosclerotic plaque activity using 18F-sodium fluoride positron emission tomography
Sex differences in coronary atherosclerotic plaque activity using 18F-sodium fluoride positron emission tomography
There are sex differences in the extent, severity, and outcomes of coronary artery disease. We aimed to assess the influen...
Noradrenergic cardiac denervation is associated with gait velocity in Parkinson disease: a dual ligand PET study
Noradrenergic cardiac denervation is associated with gait velocity in Parkinson disease: a dual ligand PET study
Preliminary data suggest that gait abnormalities in Parkinson disease (PD) may be associated with sympathetic cardiac dene...
Sedation-free pediatric [18F]FDG imaging on totalbody PET/CT with the assistance of artificial intelligence
Sedation-free pediatric [18F]FDG imaging on totalbody PET/CT with the assistance of artificial intelligence
While sedation is routinely used in pediatric PET examinations to preserve diagnostic quality, it may result in side effec...
Identification of metabolic progression and subtypes in progressive supranuclear palsy by PET molecular imaging
Identification of metabolic progression and subtypes in progressive supranuclear palsy by PET molecular imaging
Progressive supranuclear palsy (PSP) is a neurodegenerative disorder with diverse clinical presentations that are linked t...
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