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Influence of dosimetry accuracy on the correlation with treatment outcome in a preliminary PSMA radiopharmaceutical therapy study
Influence of dosimetry accuracy on the correlation with treatment outcome in a preliminary PSMA radiopharmaceutical therapy study
Despite the potential of dosimetry in optimizing personalized radiopharmaceutical therapy (RPT), its limited clinical impl...
Editorial Commentary: Should “heterogeneous response” be considered as new category for assessing treatment response in patients with breast cancer?
Editorial Commentary: Should “heterogeneous response” be considered as new category for assessing treatment response in patients with breast cancer?
Wahl RL, Jacene H, Kasamon Y, Lodge MA. From RECIST to PERCIST: Evolving Considerations for PET response criteria in solid...
Subcortical tau deposition and plasma glial fibrillary acidic protein as predictors of cognitive decline in mild cognitive impairment and Alzheimer’s disease
Subcortical tau deposition and plasma glial fibrillary acidic protein as predictors of cognitive decline in mild cognitive impairment and Alzheimer’s disease
This study aimed to investigate the correlation between subcortical tau-positron emission tomography (Tau-PET) and plasma ...
GD2-targeted theranostics of neuroblastoma with [64Cu]Cu/[177Lu]Lu-hu3F8
GD2-targeted theranostics of neuroblastoma with [64Cu]Cu/[177Lu]Lu-hu3F8
Neuroblastoma (NB) is a malignant embryonic tumour with poor prognosis and high mortality rate. The antigen gisialoganglio...
First-in-human SPECT/CT imaging of [211At]PSMA-5: targeted alpha therapy in a patient with refractory prostate cancer
First-in-human SPECT/CT imaging of [211At]PSMA-5: targeted alpha therapy in a patient with refractory prostate cancer
Ethical approval This study was conducted in accordance with the pr...
Prediction of left lobe hypertrophy with voxel-based dosimetry using integrated Y-90 PET/MRI after radioembolization of liver tumors with Y-90 microspheres
Prediction of left lobe hypertrophy with voxel-based dosimetry using integrated Y-90 PET/MRI after radioembolization of liver tumors with Y-90 microspheres
The aim of this study was to investigate the relationship between voxel-based dosimetric variables derived from Y-90 PET/M...
A deep learning method for total-body dynamic PET imaging with dual-time-window protocols
A deep learning method for total-body dynamic PET imaging with dual-time-window protocols
Prolonged scanning durations are one of the primary barriers to the widespread clinical adoption of dynamic Positron Emiss...
Comparative evaluation of a novel [18F] F-Labeled PET tracer XTR004 against [13N] ammonia in myocardial perfusion imaging for coronary artery disease
Comparative evaluation of a novel [18F] F-Labeled PET tracer XTR004 against [13N] ammonia in myocardial perfusion imaging for coronary artery disease
This study aimed to evaluate image quality, myocardial perfusion, and diagnostic performance of a novel [18F]F-labeled PET...
18F-FDG PET/CT: The turning point in eosinophilic fasciitis diagnosis in a pediatric patient
18F-FDG PET/CT: The turning point in eosinophilic fasciitis diagnosis in a pediatric patient
Ethics approval • This study was performed in line with the princip...
Preclinical evaluation of 64Cu/177Lu-labelled anti-CD30 monoclonal antibody for theranostics in CD30-positive lymphoma
Preclinical evaluation of 64Cu/177Lu-labelled anti-CD30 monoclonal antibody for theranostics in CD30-positive lymphoma
CD30 serves as an ideal therapeutic target for lymphoma, but its variable expression and high relapse rate pose challenges...
Evaluation of the safety, biodistribution, dosimetry of [18F]AlF-NYM005 and initial experience in clear cell renal cell carcinoma: an interim analysis of a prospective trial
Evaluation of the safety, biodistribution, dosimetry of [18F]AlF-NYM005 and initial experience in clear cell renal cell carcinoma: an interim analysis of a prospective trial
This first-in-human study aimed to evaluate the radiation dosimetry and whole-body biodistribution of [18F]AlF-NYM005, a n...
Visualization of tau deposition in the inferior olivary nucleus of a patient with hypertrophic olivary degeneration using [18F]-PI2620
Visualization of tau deposition in the inferior olivary nucleus of a patient with hypertrophic olivary degeneration using [18F]-PI2620
Ethics approval This study was performed in line with the principle...
Preclinical comparison of (radio)lanthanides using mass spectrometry and nuclear imaging techniques: biodistribution of lanthanide-based tumor-targeting agents and lanthanides in ionic form
Preclinical comparison of (radio)lanthanides using mass spectrometry and nuclear imaging techniques: biodistribution of lanthanide-based tumor-targeting agents and lanthanides in ionic form
With the growing interest in exploring radiolanthanides for nuclear medicine applications, the question arises as to wheth...
Exploration of (R)-[11C]YH168 as a PET tracer for imaging monoacylglycerol lipase in the brain: from mice to non-human primates
Exploration of (R)-[11C]YH168 as a PET tracer for imaging monoacylglycerol lipase in the brain: from mice to non-human primates
The monoacylglycerol lipase (MAGL) plays a pivotal role in modulating the endocannabinoid system and is considered an attr...
Rare mesenteric vein thrombophlebitis: a case for high-sensitivity long axial field-of view PET/CT imaging
Rare mesenteric vein thrombophlebitis: a case for high-sensitivity long axial field-of view PET/CT imaging
Ethical approval This study was performed in line with the principl...
Validation and clinical impact of motion-free PET imaging using data-driven respiratory gating and elastic PET-CT registration
Validation and clinical impact of motion-free PET imaging using data-driven respiratory gating and elastic PET-CT registration
Clinical whole-body (WB) PET images can be compensated for respiratory motion using data-driven gating (DDG). However, PET...
Increased uptake of [18F]MFBG in a patient with potential MEN2 syndrome
Increased uptake of [18F]MFBG in a patient with potential MEN2 syndrome
Informed consent and ethical approval This study was approved by th...
Distinguishing benign from malignant lesions with high [68 Ga]Ga-FAPI-04 uptake in oncology patients: Insights from dynamic total-body [68 Ga]Ga-FAPI-04 PET/CT
Distinguishing benign from malignant lesions with high [68 Ga]Ga-FAPI-04 uptake in oncology patients: Insights from dynamic total-body [68 Ga]Ga-FAPI-04 PET/CT
While [68 Ga]Ga-FAPI-04 PET/CT is widely used in various malignant tumors diagnosis, its specificity is challenge...
Evaluation of fibroinflammatory activity in thyroid eye disease using [18F]AlF-NOTA-FAPI-04 PET/CT: A prospective study
Evaluation of fibroinflammatory activity in thyroid eye disease using [18F]AlF-NOTA-FAPI-04 PET/CT: A prospective study
This study evaluates the value of [18F]AlF-NOTA-FAPI-04PET/CT in assessing the disease activity of thyroid eye disease (TE...
Human dose-escalation study of PET imaging CD8+ T-cell infiltration in solid malignancies with [68Ga]Ga -NODAGA-SNA006
Human dose-escalation study of PET imaging CD8+ T-cell infiltration in solid malignancies with [68Ga]Ga -NODAGA-SNA006
A noninvasive method for evaluating the infiltration of CD8+ T cells in tumors is urgently needed to monitor the response ...
A cutting-edge technology for the future of nuclear medicine
A cutting-edge technology for the future of nuclear medicine
Technical developmentsTBPET systems offer unique opportunities because of their ultra-high sensitivities and large anatomi...
Selective PET imaging of CXCR4 using the Al18F-labeled antagonist LY2510924
Selective PET imaging of CXCR4 using the Al18F-labeled antagonist LY2510924
[68Ga]PentixaFor detects C-X-C chemokine receptor type 4 (CXCR4) overexpression in various malignancies, such as multiple ...
The cerebellar glucose metabolism in moyamoya vasculopathy and its correlation with neurocognitive performance after cerebral revascularization surgery: a [18F]FDG PET study
The cerebellar glucose metabolism in moyamoya vasculopathy and its correlation with neurocognitive performance after cerebral revascularization surgery: a [18F]FDG PET study
The vascular cognitive impairment (VCI) is quite common in moyamoya vasculopathy (MMV). However, the abnormality of cerebe...
[18F]RCCB6 immunoPET/CT detects primary clear cell renal cell carcinoma
[18F]RCCB6 immunoPET/CT detects primary clear cell renal cell carcinoma
Competing interests W. Wei is on the editorial board of the Europea...
Radiopharmaceutical formulation and preliminary clinical dosimetry of [177Lu]Lu-DOTA-MGS5 for application in peptide receptor radionuclide therapy
Radiopharmaceutical formulation and preliminary clinical dosimetry of [177Lu]Lu-DOTA-MGS5 for application in peptide receptor radionuclide therapy
Radiolabelled minigastrin (MG) analogues targeting the cholecystokinin-2 receptor (CCK2R) have proven to be a promising ap...
Preclinical safety and effectiveness of a long-acting somatostatin analogue [225Ac]Ac-EBTATE against small cell lung cancer and pancreatic neuroendocrine tumors
Preclinical safety and effectiveness of a long-acting somatostatin analogue [225Ac]Ac-EBTATE against small cell lung cancer and pancreatic neuroendocrine tumors
We report the preclinical evaluation of potent long-acting [225Ac]Ac-EBTATE against SSTR2-positive small cell lung cancer ...
First-in-human administration of [161Tb]Tb-SibuDAB and comparative dosimetry with standard [177Lu]Lu-PSMA-I&T as part of the PROGNOSTICS phase Ia study
First-in-human administration of [161Tb]Tb-SibuDAB and comparative dosimetry with standard [177Lu]Lu-PSMA-I&T as part of the PROGNOSTICS phase Ia study
Ethics approval Aproved by the Ethics Committee of Northwest and Ce...
Self-supervised neural network for Patlak-based parametric imaging in dynamic [18F]FDG total-body PET
Self-supervised neural network for Patlak-based parametric imaging in dynamic [18F]FDG total-body PET
The objective of this study is to generate reliable Ki parametric images from a shortened [18F]FDG total-body PET for clin...
Safety of PSMA radioligand therapy in mCRPC patients with preexisting moderate to severe thrombocytopenia
Safety of PSMA radioligand therapy in mCRPC patients with preexisting moderate to severe thrombocytopenia
Aim of this study was to analyze the safety of prostate-specific membrane antigen radioligand therapy (PSMA-RLT) in patien...
A deep learning method for the recovery of standard-dose imaging quality from ultra-low-dose PET on wavelet domain
A deep learning method for the recovery of standard-dose imaging quality from ultra-low-dose PET on wavelet domain
Recent development in positron emission tomography (PET) dramatically increased the effective sensitivity by increasing th...
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