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Abundance of the Membrane Proteome in Yeast Cells Lacking Spc1, a Non-catalytic Subunit of the Signal Peptidase Complex
Abundance of the Membrane Proteome in Yeast Cells Lacking Spc1, a Non-catalytic Subunit of the Signal Peptidase Complex
The signal peptidase complex (SPC) mediates processing of signal peptides of secretory precursors. But, recent studies sho...
Beyond Hormones: Investigating the Impact of Progesterone Receptor Membrane Component 1 in Lung Adenocarcinoma
Beyond Hormones: Investigating the Impact of Progesterone Receptor Membrane Component 1 in Lung Adenocarcinoma
Progesterone Receptor Membrane Component 1 (PGRMC1) is a candidate oncogene with a prominent involvement in the pathogenes...
Quantal Properties of Voltage-Dependent Ca2+ Release in Frog Skeletal Muscle Persist After Reduction of [Ca2+] in the Sarcoplasmic Reticulum
Quantal Properties of Voltage-Dependent Ca2+ Release in Frog Skeletal Muscle Persist After Reduction of [Ca2+] in the Sarcoplasmic Reticulum
In skeletal muscle, the Ca2+ release flux elicited by a voltage clamp pulse rises to an early peak that inactivates rapidl...
Construction and Analysis of a Mitochondrial Metabolism-Related Prognostic Model for Breast Cancer to Evaluate Survival and Immunotherapy
Construction and Analysis of a Mitochondrial Metabolism-Related Prognostic Model for Breast Cancer to Evaluate Survival and Immunotherapy
As one of the most prevalent malignancies among women, breast cancer (BC) is tightly linked to metabolic dysfunction. Howe...
Bioinformatic Study of Possible Acute Regulation of Acid Secretion in the Stomach
Bioinformatic Study of Possible Acute Regulation of Acid Secretion in the Stomach
The gastric H+,K+-ATPase is an integral membrane protein which derives energy from the hydrolysis of ATP to transport H+ i...
Potential Role of Nrf2, HER2, and ALDH in Cancer Stem Cells: A Narrative Review
Potential Role of Nrf2, HER2, and ALDH in Cancer Stem Cells: A Narrative Review
Cancer is one of the main causes of death among humans, second only to cardiovascular diseases. In recent years, numerous ...
Study of the Membrane Activity of the Synthetic Peptide ∆M3 Against Extended-Spectrum β-lactamase Escherichia coli Isolates
Study of the Membrane Activity of the Synthetic Peptide ∆M3 Against Extended-Spectrum β-lactamase Escherichia coli Isolates
Escherichia coli is the most common microorganism causing nosocomial or community-acquired bacteremia, and extended-spectr...
Streamlined Biotinylation, Enrichment and Analysis for Enhanced Plasma Membrane Protein Identification Using TurboID and TurboID-Start Biotin Ligases
Streamlined Biotinylation, Enrichment and Analysis for Enhanced Plasma Membrane Protein Identification Using TurboID and TurboID-Start Biotin Ligases
Plasma membrane proteins (PMPs) play pivotal roles in various cellular events and are crucial in disease pathogenesis, mak...
Isolated Cardiac Ryanodine Receptor Function Varies Between Mammals
Isolated Cardiac Ryanodine Receptor Function Varies Between Mammals
Concerted robust opening of cardiac ryanodine receptors’ (RyR2) Ca2+ release 1oplasmic reticulum (SR) is fundamental...
Schisandrin B Alleviates LPS Induced Mitochondrial Damage in C28I2 Cells
Schisandrin B Alleviates LPS Induced Mitochondrial Damage in C28I2 Cells
Osteoarthritis is a common joint disease characterized by damage to the joint cartilage that occurs throughout the entire ...
Correction: Role of Hydrophobic Amino-Acid Side-Chains in the Narrow Selectivity Filter of the CFTR Chloride Channel Pore in Conductance and Selectivity
Correction: Role of Hydrophobic Amino-Acid Side-Chains in the Narrow Selectivity Filter of the CFTR Chloride Channel Pore in Conductance and Selectivity
Relationships between amino-acid side-chain volume at position 337, single channel conductance, and SCN– permeability. a C...
Effects of Chemical Fixatives on Kinetic Measurements of Biomolecular Interaction on Cell Membrane
Effects of Chemical Fixatives on Kinetic Measurements of Biomolecular Interaction on Cell Membrane
Understanding the interaction between ligands and membrane proteins is important for drug design and optimization. Althoug...
Lidocaine Inhibits Rat Prostate Cancer Cell Invasiveness and Voltage-Gated Sodium Channel Expression in Plasma Membrane
Lidocaine Inhibits Rat Prostate Cancer Cell Invasiveness and Voltage-Gated Sodium Channel Expression in Plasma Membrane
There is increasing evidence, mostly from breast cancer, that use of local anaesthetics during surgery can inhibit disease...
Identification of Prognostic and Immune Characteristics of Two Lung Adenocarcinoma Subtypes Based on TRPV Channel Family Genes
Identification of Prognostic and Immune Characteristics of Two Lung Adenocarcinoma Subtypes Based on TRPV Channel Family Genes
Lung adenocarcinoma (LUAD) is one of the deadliest malignant tumors worldwide. Transient receptor potential vanilloid (TRP...
Correction to: Forces and Flows at Cell Surfaces
Correction to: Forces and Flows at Cell Surfaces
I am delighted and honored to introduce the following essay by Dr. Aurelia Honerkamp-Smith, an Assistant Professor in the ...
Host Lipid Manipulation by Intracellular Bacteria: Moonlighting for Immune Evasion
Host Lipid Manipulation by Intracellular Bacteria: Moonlighting for Immune Evasion
Lipids are complex organic molecules that fulfill energy demands and sometimes act as signaling molecules. They are mostly...
Track and Field of the Journal of Membrane Biology
Track and Field of the Journal of Membrane Biology
As my 5-year tenure as Editor-in-Chief of the Journal of Membrane Biology reaches the...
Exploration of the Catalytic Cycle Dynamics of Vigna Radiata H+–Translocating Pyrophosphatases Through Hydrogen–Deuterium Exchange Mass Spectrometry
Exploration of the Catalytic Cycle Dynamics of Vigna Radiata H+–Translocating Pyrophosphatases Through Hydrogen–Deuterium Exchange Mass Spectrometry
Vigna radiata H+–translocating pyrophosphatases (VrH+-PPases, EC 3.6.1.1) are present in various endomembranes of pl...
Role of Hydrophobic Amino-Acid Side-Chains in the Narrow Selectivity Filter of the CFTR Chloride Channel Pore in Conductance and Selectivity
Role of Hydrophobic Amino-Acid Side-Chains in the Narrow Selectivity Filter of the CFTR Chloride Channel Pore in Conductance and Selectivity
Cystic fibrosis is caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) anion channel. St...
Forces and Flows at Cell Surfaces
Forces and Flows at Cell Surfaces
Flow is an important physiological signal and modulates a variety of cell functions. However, the molecular mechanisms tha...
The Effect of Benzyl Alcohol on the Voltage-Current Characteristics of Tethered Lipid Bilayers
The Effect of Benzyl Alcohol on the Voltage-Current Characteristics of Tethered Lipid Bilayers
In this study a lipid bilayer membrane model was used in which the bilayer is tethered to a solid substrate with molecular...
Cationic Proteins Rich in Lysine Residue Trigger Formation of Non-bilayer Lipid Phases in Model and Biological Membranes: Biophysical Methods of Study
Cationic Proteins Rich in Lysine Residue Trigger Formation of Non-bilayer Lipid Phases in Model and Biological Membranes: Biophysical Methods of Study
Cationic membrane-active toxins are the most abundant group of proteins in the venom of snakes and insects. Cationic prote...
The Functionality of Membrane-Inserting Proteins and Peptides: Curvature Sensing, Generation, and Pore Formation
The Functionality of Membrane-Inserting Proteins and Peptides: Curvature Sensing, Generation, and Pore Formation
Proteins and peptides with hydrophobic and amphiphilic segments are responsible for many biological functions. The sensing...
Correction: Hans Ussing Memorial Issue: Epithelial Membrane Transport
Correction: Hans Ussing Memorial Issue: Epithelial Membrane Transport
Share this articleAnyone you share the following link with will be able to read this content:Get shareable linkSorry, a sh...
Effect of γ-Oryzanol on the LE–LC Phase Coexistence Region of DPPC Langmuir Monolayer
Effect of γ-Oryzanol on the LE–LC Phase Coexistence Region of DPPC Langmuir Monolayer
We have studied the effect of relative composition of γ-Oryzanol (γ-Or) on the liquid expanded–liquid cond...
Computational Study on Effect of KCNQ1 P535T Mutation in a Cardiac Ventricular Tissue
Computational Study on Effect of KCNQ1 P535T Mutation in a Cardiac Ventricular Tissue
Heart diseases such as arrhythmia are the main causes of sudden death. Arrhythmias are typically caused by mutations in sp...
Assessment of Purity, Functionality, Stability, and Lipid Composition of Cyclofos-nAChR-Detergent Complexes from Torpedo californica Using Lipid Matrix and Macroscopic Electrophysiology
Assessment of Purity, Functionality, Stability, and Lipid Composition of Cyclofos-nAChR-Detergent Complexes from Torpedo californica Using Lipid Matrix and Macroscopic Electrophysiology
The main objective of the present study was to find detergents that can maintain the functionality and stability of the To...
Peptide Flexibility and the Hydrophobic Moment are Determinants to Evaluate the Clinical Potential of Magainins
Peptide Flexibility and the Hydrophobic Moment are Determinants to Evaluate the Clinical Potential of Magainins
Using a flexibility prediction algorithm and in silico structural modeling, we have calculated the intrinsic flexibility o...
Research Progress on TRPA1 in Diseases
Research Progress on TRPA1 in Diseases
For a long time, the physiological activity of TRP ion channels and the response to various stimuli have been the focus of...
Rapid Pacing Decreases L-type Ca2+ Current and Alters Cacna1c Isogene Expression in Primary Cultured Rat Left Ventricular Myocytes
Rapid Pacing Decreases L-type Ca2+ Current and Alters Cacna1c Isogene Expression in Primary Cultured Rat Left Ventricular Myocytes
The L-type calcium current (ICaL) is the first step in cardiac excitation–contraction-coupling and plays an importan...
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