×
Close
註冊
登入
主页
用户
博客
照片
视频
医学图书S馆
医学图书M馆
医学图书D馆
医学术语
群组
活动
用户工具
用户指南
问答
谁看过我
反馈
语言
English
中文
推广
×
Close
CN1699 Our Business - Guide for Agents
分类
Toxicology
4430
Global Medical University
5503
Allergy
1827
Anatomy & Morphology
1598
Andrology
414
Anesthesia & Intensive Care
1337
Anesthesiology
5810
Audiology & Speech-Language Pathology
335
Behavioral Sciences
104
Biochemical Research Methods
7365
Biochemistry & Molecular Biology
31245
Biodiversity Conservation
334
Biology
8923
Biophysics
9258
Biotechnology & Applied Microbiology
8814
Cardiac & Cardiovascular Systems
32852
Cardiovascular & Respiratory Systems
1493
Cell & Tissue Engineering
699
Cell Biology
11369
Chemistry, Analytical
4394
Chemistry, Applied
11818
Chemistry, Medicinal
8916
Chemistry, Multidisciplinary
19556
Clinical Immunology & Infectious Disease
456
Clinical Medicine
9103
Clinical Neurology
17187
Clinical Psychology & Psychiatry
1491
Critical Care Medicine
3416
Dentistry, Oral Surgery & Medicine
13936
Dermatology
7771
Developmental Biology
7253
Ecology
645
Education, Scientific Disciplines
2004
Emergency Medicine
4342
Endocrinology, Metabolism & Nutrition
25592
Engineering, Biomedical
3782
Entomology
449
Environmental Medicine & Public Health
4967
Evolutionary Biology
267
Gastroenterology & Hepatology
12628
General & Internal Medicine
7425
Genetics & Heredity
15855
Geriatrics & Gerontology
5231
Gerontology
349
Health Care Sciences & Services
16745
Health Policy & Services
613
Hematology
5667
Immunology
26778
Infectious Diseases
14578
Integrative & Complementary Medicine
2951
Medical Ethics
1208
Medical Informatics
2350
Medical Laboratory Technology
433
Medicine, General & Internal
46866
Medicine, Legal
534
Medicine, Research & Experimental
19040
Microbiology
24681
Mycology
0
Nanoscience & Nanotechnology
5462
Neuroimaging
1381
Neurology
4778
Neurosciences
42137
Nursing
9874
Nutrition & Dietetics
8155
Obstetrics & Gynecology
8650
Oncology
55180
Ophthalmology
10335
Optics
4521
Orthopedics
12116
Orthopedics, Rehabilitation & Sports Medicine
1856
Otolaryngology
1573
Otorhinolaryngology
5130
Parasitology
1077
Pathology
5154
Pediatrics
22578
Peripheral Vascular Disease
4859
Pharmacology & Pharmacy
36969
Pharmacology/Toxicology
13056
Physiology
9339
Polymer Science
597
Primary Health Care
853
Psychiatry
20882
Psychology
5332
Psychology, Applied
93
Psychology, Biological
352
Psychology, Clinical
829
Psychology, Developmental
222
Psychology, Educational
137
Psychology, Experimental
133
Psychology, Mathematical
0
Psychology, Multidisciplinary
1624
Psychology, Psychoanalysis
41
Psychology, Social
116
Public Health & Health Care Science
2308
Public, Environmental & Occupational Health
28703
Quantum Science & Technology
0
Radiology, Nuclear Medicine & Imaging
12981
Radiology, Nuclear Medicine & Medical Imaging
8108
Rehabilitation
3078
Remote Sensing
0
Reproductive Biology
3028
Reproductive Medicine
1241
Research/Laboratory Medicine & Medical Technology
4176
Respiratory System
7604
Rheumatology
6242
Social Sciences, Biomedical
1238
Substance Abuse
2815
Surgery
35645
Transplantation
933
Tropical Medicine
314
Urology & Nephrology
13706
Veterinary Sciences
35
Virology
2490
Zoology
0
渠道
ARCHIVES OF TOXICOLOGY
606
Medrxiv - Toxicology
36
CELL BIOLOGY AND TOXICOLOGY
289
DNA REPAIR
274
INFLAMMOPHARMACOLOGY
595
INTEGRATED ENVIRONMENTAL ASSESSMENT AND MANAGEMENT
161
JOURNAL OF APPLIED TOXICOLOGY
176
JOURNAL OF EXPOSURE SCIENCE AND ENVIRONMENTAL EPIDEMIOLOGY
310
REPRODUCTIVE TOXICOLOGY
1
TOXINS
1218
ENVIRONMENTAL AND MOLECULAR MUTAGENESIS
28
NEUROTOXICOLOGY AND TERATOLOGY
0
TOXICOLOGIC PATHOLOGY
45
TOXICOLOGY AND INDUSTRIAL HEALTH
43
TOXICOLOGY REPORTS
517
TOXICOLOGICAL RESEARCH
49
JOURNAL OF XENOBIOTICS
42
REVIEWS OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY
40
SCI时时刷
search
全部
推荐
+
Excavatolide C/cisplatin combination induces antiproliferation and drives apoptosis and DNA damage in bladder cancer cells
Excavatolide C (EXCC), a marine coral-derived compound, exhibits an antiproliferation effect on bladder cancer cells. The ...
Archives Of Toxicology
comment
0
thumb_up
0
Effects of marine biotoxins on drug-metabolizing cytochrome P450 enzymes and their regulation in mammalian cells
Marine biotoxins are a heterogenous group of natural toxins, which are able to trigger different types of toxicological re...
Archives Of Toxicology
comment
0
thumb_up
0
PBTK model-based analysis of CYP3A4 induction and the toxicokinetics of the pyrrolizidine alkaloid retrorsine in man
Cytochrome P450 (CYP)3A4 induction by drugs and pesticides plays a critical role in the enhancement of pyrrolizidine alkal...
Archives Of Toxicology
comment
0
thumb_up
0
Formation of potentially toxic metabolites of drugs in reactions catalyzed by human drug-metabolizing enzymes
Data are presented on the formation of potentially toxic metabolites of drugs that are substrates of human drug metabolizi...
Archives Of Toxicology
comment
0
thumb_up
0
Multi-organ developmental toxicity and its characteristics in fetal mice induced by dexamethasone at different doses, stages, and courses during pregnancy
Dexamethasone is widely used in pregnant women at risk of preterm birth to reduce the occurrence of neonatal respiratory d...
Archives Of Toxicology
comment
0
thumb_up
0
CircRNA: a rising therapeutic strategy for lung injury induced by pulmonary toxicants
Lung injury has been a serious medical problem that requires new therapeutic approaches and biomarkers. Circular RNAs (cir...
Archives Of Toxicology
comment
0
thumb_up
0
Role of the complement system in kidney cell death induced by Loxosceles venom Sphingomyelinases D
Envenomation by Loxosceles spiders can result in local and systemic pathologies. Systemic loxoscelism, which can lead to d...
Archives Of Toxicology
comment
0
thumb_up
0
The estimation of acute oral toxicity (LD50) of G-series organophosphorus-based chemical warfare agents using quantitative and qualitative toxicology in silico methods
The idea of this study was the estimation of the theoretical acute toxicity (t-LD50, rat, oral dose) of organophosphorus-b...
Archives Of Toxicology
comment
0
thumb_up
0
Cytogenotoxicity and inflammatory response in liver of rats exposed to different doses of cannabis nano emulsions
Cannabis is the most used illicit substance for recreational purposes around the world. However, it has become increasingl...
Archives Of Toxicology
comment
0
thumb_up
0
Prediction of cytochrome P450-mediated bioactivation using machine learning models and in vitro validation
Cytochrome P450 (P450)-mediated bioactivation, which can lead to the hepatotoxicity through the formation of reactive meta...
Archives Of Toxicology
comment
0
thumb_up
0
Characterization of pathological changes in the olfactory system of mice exposed to methylmercury
Methylmercury (MeHg) is a well-known environmental neurotoxicant that causes severe brain disorders such as Minamata disea...
Archives Of Toxicology
comment
0
thumb_up
0
Demonstrating the reliability of in vivo metabolomics based chemical grouping: towards best practice
While grouping/read-across is widely used to fill data gaps, chemical registration dossiers are often rejected due to weak...
Archives Of Toxicology
comment
0
thumb_up
0
Flavonoids commonly induce hormetic responses
The present paper provides a new perspective of previously published findings by Siwak (Food Chem 141:1227–1241, 201...
Archives Of Toxicology
comment
0
thumb_up
0
ATF4 in cellular stress, ferroptosis, and cancer
Activating transcription factor 4 (ATF4), a member of the ATF/cAMP response element-binding (CREB) family, plays a critica...
Archives Of Toxicology
comment
0
thumb_up
0
Identification of key neuronal mechanisms triggered by dimethyl fumarate in SH-SY5Y human neuroblastoma cells through a metabolomic approach
Dimethyl fumarate (DMF) is an old drug used for psoriasis treatment that has recently been repurposed to treat relapseR...
Archives Of Toxicology
comment
0
thumb_up
0
In vitro and in vivo metabolic activation and hepatotoxicity of chlorzoxazone mediated by CYP3A
Chlorzoxazone (CZX), a benzoxazolone derivative, has been approved for the treatment of musculoskeletal disorders to relie...
Archives Of Toxicology
comment
0
thumb_up
0
Recent advances and current challenges of new approach methodologies in developmental and adult neurotoxicity testing
Adult neurotoxicity (ANT) and developmental neurotoxicity (DNT) assessments aim to understand the adverse effects and unde...
Archives Of Toxicology
comment
0
thumb_up
0
Involvement of per- and polyfluoroalkyl compounds in tumor development
Per- and polyfluoroalkyl substances (PFAS) are a large group of synthetic persistent chemicals, which are used in many ind...
Archives Of Toxicology
comment
0
thumb_up
0
Elevated aerobic glycolysis driven by p62-mTOR axis promotes arsenic-induced oncogenic phenotypes in human mammary epithelial cells
Chronic arsenic exposure is considered to increase the risk of breast cancer. p62 is a multifunctional adaptor protein tha...
Archives Of Toxicology
comment
0
thumb_up
0
Toxicokinetics of homosalate in humans after dermal application: applicability of oral-route data for exposure assessment by human biomonitoring
Homosalate (HMS) is a UV filter used in sunscreens and personal care products as a mixture of cis- and trans-isomers. Syst...
Archives Of Toxicology
comment
0
thumb_up
0
Cellular senescence gene TACC3 associated with colorectal cancer risk via genetic and DNA methylated alteration
Cell senescence genes play a vital role in the pathogenesis of colorectal cancer, a process that may involve the triggerin...
Archives Of Toxicology
comment
0
thumb_up
0
Several lines of antioxidant defense against oxidative stress: antioxidant enzymes, nanomaterials with multiple enzyme-mimicking activities, and low-molecular-weight antioxidants
Reactive oxygen species (ROS) and reactive nitrogen species (RNS) are well recognized for playing a dual role, since they ...
Archives Of Toxicology
comment
0
thumb_up
0
Use of human predictive patch test (HPPT) data for the classification of skin sensitization hazard and potency
Since the 1940s, patch tests in healthy volunteers (Human Predictive Patch Tests, HPPTs) have been used to identify chemic...
Archives Of Toxicology
comment
0
thumb_up
0
Combined use of multiparametric high-content-screening and in vitro circadian reporter assays in neurotoxicity evaluation
Accumulating evidence indicates that chronic circadian rhythm disruption is associated with the development of neurodegene...
Archives Of Toxicology
comment
0
thumb_up
0
Future in the past: paternal reprogramming of offspring phenotype and the epigenetic mechanisms
That certain preconceptual paternal exposures reprogram the developmental phenotypic plasticity in future generation(s) ha...
Archives Of Toxicology
comment
0
thumb_up
0
Circular RNA MKLN1 promotes epithelial-mesenchymal transition in pulmonary fibrosis by regulating the miR-26a/b-5p/CDK8 axis in human alveolar epithelial cells and mice models
Pulmonary fibrosis involves destruction of the lung parenchyma and extracellular matrix deposition. Effective treatments f...
Archives Of Toxicology
comment
0
thumb_up
0
Acetaminophen overdose causes a breach of the blood–bile barrier in mice but not in rats
Acetaminophen (APAP) is known to cause a breach of the blood–bile barrier in mice that, via a mechanism called futil...
Archives Of Toxicology
comment
0
thumb_up
0
Integrated data from intravital imaging and HPLC–MS/MS analysis reveal large interspecies differences in AFB1 metabolism in mice and rats
Large interspecies differences between rats and mice concerning the hepatotoxicity and carcinogenicity of aflatoxin B1 (AF...
Archives Of Toxicology
comment
0
thumb_up
0
The acute toxicity of Novichok's degradation products using quantitative and qualitative toxicology in silico methods
The emergence of Novichok agents, potent organophosphorus nerve agents, has spurred the demand for advanced analytical met...
Archives Of Toxicology
comment
0
thumb_up
0
YES1 as a potential target to overcome drug resistance in EGFR-deregulated non-small cell lung cancer
Epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitors (TKIs) such as gefitinib and osimertinib have primarily...
Archives Of Toxicology
comment
0
thumb_up
0
阅读更多
Modal title
×
Modal title
×
分享
登入
Global News and Health Forum
Join Now!
馬上登入
記住我
忘記密碼?
或者使用
Linkedin