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Outcomes of patients with Richter transformation who received no prior chemoimmunotherapy for their CLL
Outcomes of patients with Richter transformation who received no prior chemoimmunotherapy for their CLL
Competing interests A.S.K. received research funding from AstraZeneca and ...
High WEE1 expression is independently linked to poor survival in multiple myeloma
High WEE1 expression is independently linked to poor survival in multiple myeloma
Current prognostic scores in multiple myeloma (MM) currently rely on disease burden and a limited set of genomic alteratio...
Peritoneal lymphomatosis with CD5-positive diffuse large B-cell lymphoma
Peritoneal lymphomatosis with CD5-positive diffuse large B-cell lymphoma
Miyazaki K, Asano N, Yamada T, Miyawaki K, Sakai R, Igarashi T, et al. DA-EPOCH-R combined with high-dose methotrexate in ...
A novel stroma-dependent leukemia cell line from a patient with mixed-phenotype acute leukemia with Ph chromosome and PAX5 mutation
A novel stroma-dependent leukemia cell line from a patient with mixed-phenotype acute leukemia with Ph chromosome and PAX5 mutation
Mixed phenotype acute leukemia (MPAL) is a rare and aggressive form of leukemia with a poor prognosis and no established t...
A large expert-annotated single-cell peripheral blood dataset for hematological disease diagnostics
A large expert-annotated single-cell peripheral blood dataset for hematological disease diagnostics
medRxiv - The Preprint Server for Health Sciences
Clonal plasma cell proportion in the synthetic phase identifies a unique high-risk cohort in multiple myeloma
Clonal plasma cell proportion in the synthetic phase identifies a unique high-risk cohort in multiple myeloma
Risk stratification models based on cytogenetics and disease burden help identify high-risk patients with newly diagnosed ...
Effect of pre-transplant cytoreductive therapy on the outcomes of patients with MDS or secondary AML evolving from MDS undergoing allo-HSCT: a secondary analysis of an RCT
Effect of pre-transplant cytoreductive therapy on the outcomes of patients with MDS or secondary AML evolving from MDS undergoing allo-HSCT: a secondary analysis of an RCT
Allogeneic hematopoietic stem cell transplantation (allo-HSCT) remains the o...
The CD64/CD28/CD3ζ chimeric receptor reprograms T-cell metabolism and promotes T-cell persistence and immune functions while triggering antibody-independent and antibody-dependent cytotoxicity
The CD64/CD28/CD3ζ chimeric receptor reprograms T-cell metabolism and promotes T-cell persistence and immune functions while triggering antibody-independent and antibody-dependent cytotoxicity
Recent studies have shown that CD32/CD8a/CD28/CD3ζ chimeric receptor cells directly kill breast cancer cells, suggest...
Predictors of prognosis and overall survival in pediatric mucoepidermoid carcinoma of salivary glands: A systematic review
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The role of cGAS-STING in remodeling the tumor immune microenvironment induced by radiotherapy
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Karyotype evolution of myelodysplastic syndrome and acute myeloid leukemia with TP53 mutations
Karyotype evolution of myelodysplastic syndrome and acute myeloid leukemia with TP53 mutations
To clarify karyotype evolution of myelodysplastic syndrome or acute myeloid leukemia with TP53 mutations (MDS/AML-TP53), w...
Engineered oncolytic virus coated with anti-PD-1 and alendronate for ameliorating intratumoral T cell hypofunction
Engineered oncolytic virus coated with anti-PD-1 and alendronate for ameliorating intratumoral T cell hypofunction
Glioblastoma is a highly aggressive and devastating primary brain tumor that is resistant to conventional therapies. Oncol...
IHCH9033, a novel class I HDAC inhibitor, synergizes with FLT3 inhibitor and rescues quizartinib resistance in FLT3-ITD AML via enhancing DNA damage response
IHCH9033, a novel class I HDAC inhibitor, synergizes with FLT3 inhibitor and rescues quizartinib resistance in FLT3-ITD AML via enhancing DNA damage response
Despite initial success with FLT3 inhibitors (FLT3is), outcomes for FLT3-ITD acute myeloid leukemia (AML) patients remain ...
Zanubrutinib in Japanese treatment-naive and relapsed/refractory patients with Waldenström macroglobulinemia and CLL/SLL
Zanubrutinib in Japanese treatment-naive and relapsed/refractory patients with Waldenström macroglobulinemia and CLL/SLL
Zanubrutinib is a selective second-generation Bruton tyrosine kinase inhibitor approved in various B-cell malignancies glo...
T-cell lymphoproliferative disorder with a STAT3 mutation causing a lymphocytic variant of hypereosinophilic-like syndrome without eosinophilia
T-cell lymphoproliferative disorder with a STAT3 mutation causing a lymphocytic variant of hypereosinophilic-like syndrome without eosinophilia
Lymphocytic variant of hypereosinophilic syndrome (LV-HES) is a rare T-cell lymphoproliferative disorder characterized by ...
Unraveling the link between cholesterol and immune system in cancer: From biological mechanistic insights to clinical evidence. A narrative review
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Performance of CpG-oligonucleotide DSP30 and interleukin-2 in the cytogenetic study of mature B-cell neoplasms: A systematic review and meta-analysis
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Clinical practice guidelines for management of disseminated intravascular coagulation in Japan 2024: significance of guidelines developed for each underlying disease
Clinical practice guidelines for management of disseminated intravascular coagulation in Japan 2024: significance of guidelines developed for each underlying disease
Disseminated intravascular coagulation (DIC) is a severe condition characterized by systemic, persistent activation of coa...
Bispecific Antibody Therapy for Lymphoma
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Correction: A simplified, two-factor clinical prognostic scoring system for patients with newly diagnosed Hodgkins Lymphoma
Open Access This article is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4....
Decitabine with etoposide is effective in TP53 mutated myeloid tumors via overcoming differentiation block
Decitabine with etoposide is effective in TP53 mutated myeloid tumors via overcoming differentiation block
Myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML) represent a...
CAR-macrophages targets CD26 to eliminate chronic myeloid leukemia stem cells
CAR-macrophages targets CD26 to eliminate chronic myeloid leukemia stem cells
Chronic myeloid leukemia stem cells (CML-LSCs), which exhibit resistance to tyrosine kinase inhibitors (TKIs), are the lea...
Distinct response to IL-1β blockade in liver- and lung-specific metastasis mouse models of pancreatic cancer with heterogeneous tumor microenvironments
Distinct response to IL-1β blockade in liver- and lung-specific metastasis mouse models of pancreatic cancer with heterogeneous tumor microenvironments
Pancreatic ductal adenocarcinoma (PDAC) is characterized by a heterogeneous tumor microenvironment (TME). The mechanism by...
Revolutionizing prostate cancer therapy: Artificial intelligence – Based nanocarriers for precision diagnosis and treatment
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Endocrinological toxicities related to immunotherapy combinations for advanced renal cell carcinoma: Practical expert-based management recommendations
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CAR T-cell therapy landscape in pediatric, adolescent and young adult oncology – A comprehensive analysis of clinical trials
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CD3/CD20/CD45 negative leukemia cutis
CD3/CD20/CD45 negative leukemia cutis
A 56-year-old male presented to the clinic with complaints of multiple skin lesions. A complete blood count (CBC) was not ...
Future directions in the evaluation and management of newly diagnosed metastatic cancer
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Molecular features and clinical actionability of gene fusions in colorectal cancer
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Efficacy and safety of the thiotepa–busulfan conditioning regimen as for autologous stem cell transplantation in relapsed/refractory systemic diffuse large B cell lymphoma: a single-center retrospective study
Efficacy and safety of the thiotepa–busulfan conditioning regimen as for autologous stem cell transplantation in relapsed/refractory systemic diffuse large B cell lymphoma: a single-center retrospective study
High-dose chemotherapy followed by autologous stem cell transplantation (ASCT) is a standard treatment for relapsed diffus...
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