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Frontline Ph-negative B-cell precursor acute lymphoblastic leukemia treatment and the emerging role of blinatumomab
Frontline Ph-negative B-cell precursor acute lymphoblastic leukemia treatment and the emerging role of blinatumomab
This narrative review seeks to summarize chemotherapeutic regimens commonly used for patients with newly diagnosed Philade...
What have we learned about TP53-mutated acute myeloid leukemia?
What have we learned about TP53-mutated acute myeloid leukemia?
TP53 is a tumor suppressor gene frequently mutated in human cancers and is generally associated with poor outcomes. TP53 m...
Association between early anti-cytomegalovirus therapy and the incidence of chronic graft-versus-host disease
Association between early anti-cytomegalovirus therapy and the incidence of chronic graft-versus-host disease
Ganciclovir and foscarnet are two representative anti-cytomegalovirus (CMV) agents. A previous regional study revealed a l...
Impact of TP53 mutation on genetic and cellular hierarchy profile in complex karyotype AML/MDS with increased blasts
Impact of TP53 mutation on genetic and cellular hierarchy profile in complex karyotype AML/MDS with increased blasts
Complex karyotype (CK), occurring in 10–15% of adult acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS) cases...
Natural killer cell biology and therapy in multiple myeloma: challenges and opportunities
Natural killer cell biology and therapy in multiple myeloma: challenges and opportunities
Despite therapeutic advancements, multiple myeloma (MM) remains incurable. NK cells have emerged as a promising option for...
High-throughput screening for optimizing adoptive T cell therapies
High-throughput screening for optimizing adoptive T cell therapies
Adoptive T cell therapy is a pivotal strategy in cancer immunotherapy, demonstrating potent clinical efficacy. However, it...
Iron deficiency and phlebotomy in patients with polycythemia vera
Iron deficiency and phlebotomy in patients with polycythemia vera
Polycythemia vera (PV) is a myeloproliferative neoplasm that is associated with an elevated risk of thrombosis. Treatment ...