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Reactions of lipid hydroperoxides and how they may contribute to ferroptosis sensitivity
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Finding ways into the cytosol: Peptide-mediated approaches for delivering proteins into cells
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Recent applications of fluorescence correlation spectroscopy in live cells
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RNA nanotechnology on the horizon: Self-assembly, chemical modifications, and functional applications
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Recent advances in engineering microorganisms for the production of natural food colorants
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The non-catalytic domains of O-GlcNAc cycling enzymes present new opportunities for function-specific control
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Probing metalloenzyme dynamics in living systems: Contemporary advances in fluorescence imaging tools and applications
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Site-specific bioconjugation and nuclear imaging
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Molecular anchoring and fluorescent labeling in animals compatible with tissue clearing for 3D imaging
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New reactions by pyridoxal phosphate-dependent enzymes
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Specific signaling by nicotinamide adenine dinucleotide oxidases – Role of their site of action
Specific signaling by nicotinamide adenine dinucleotide oxidases – Role of their site of action
Nicotinamide adenine dinucleotide (NADPH) oxidases are a family of enzymes responsible for generating superoxide anions (O...
Biosynthesis of isonitrile lipopeptides
Biosynthesis of isonitrile lipopeptides
Isonitrile-containing natural products isolated from bacteria, fungi, sponges, and plants have attracted wide attention in...
Multinuclear non-heme iron dependent oxidative enzymes (MNIOs) involved in unusual peptide modifications
Multinuclear non-heme iron dependent oxidative enzymes (MNIOs) involved in unusual peptide modifications
Multinuclear non-heme iron dependent oxidative enzymes (MNIOs), formerly known as domain of unknown function 692 (DUF692),...
New analytical methods focusing on polar metabolite analysis in mass spectrometry and NMR-based metabolomics
New analytical methods focusing on polar metabolite analysis in mass spectrometry and NMR-based metabolomics
Following in the footsteps of genomics and proteomics, metabolomics has revolutionised the way we investigate and understa...
F420-dependent transformations in biosynthesis of secondary metabolites
F420-dependent transformations in biosynthesis of secondary metabolites
Cofactor F420 has been historically known as the “methanogenic redox cofactor”. It is now recognised that F420 has essenti...
Lanthanide-dye hybrid luminophores for advanced NIR-II bioimaging
Lanthanide-dye hybrid luminophores for advanced NIR-II bioimaging
In vivo luminescence imaging employs the contrast generated by photoluminescent agents (known as luminophores) to visualiz...
Oxygen-transfer reactions by enzymatic flavin-N5 oxygen adducts—Oxidation is not a must
Oxygen-transfer reactions by enzymatic flavin-N5 oxygen adducts—Oxidation is not a must
Flavoenzymes catalyze numerous redox reactions including the transfer of an O2-derived oxygen atom to organic substrates, ...
Novel types of RiPP-modifying enzymes
Novel types of RiPP-modifying enzymes
Novel discoveries in natural product biosynthesis reveal hidden bioactive compounds and expand our knowledge in enzymology...
Peroxynitrite: a multifaceted oxidizing and nitrating metabolite
Peroxynitrite: a multifaceted oxidizing and nitrating metabolite
Volume 80, June 2024, 102459Author links open overlay panel, , Highlights•Peroxynitrite is a highly reactive oxidant forme...
Recent advances in photoaffinity labeling strategies to capture Glycan–Protein interactions
Recent advances in photoaffinity labeling strategies to capture Glycan–Protein interactions
Glycans decorate all cells and are critical mediators of cellular processes through recognition by glycan-binding proteins...
Functions and mechanisms of enzymes assembling lignans and norlignans
Functions and mechanisms of enzymes assembling lignans and norlignans
Lignans and norlignans are distributed throughout the plant kingdom and exhibit diverse chemical structures and biological...
Towards chemoenzymatic labeling strategies for profiling protein glycosylation
Towards chemoenzymatic labeling strategies for profiling protein glycosylation
Protein glycosylation is a class of prevalent modification of proteins involved in multiple biological functions [1, 2, 3]...
Recent advances in minimal fluorescent probes for optical imaging
Recent advances in minimal fluorescent probes for optical imaging
Fluorescent probes have revolutionized biological imaging by enabling the real-time visualization of cellular processes un...
Advances in the understanding and exploitation of carbohydrate-active enzymes
Advances in the understanding and exploitation of carbohydrate-active enzymes
KeywordsCarbohydrate-active enzymesActivity-based probesGlycoside hydrolasesGlycosyltransferasesGlycansChemoenzymatic synt...
Advances in understanding and exploiting Siglec–glycan interactions
Advances in understanding and exploiting Siglec–glycan interactions
Siglecssialic-acid-binding immunoglobulin-type lectinsSAMPself-associated molecular patternITIMimmunoreceptor-tyrosine-bas...
Chemical biology tools to probe bacterial glycans
Chemical biology tools to probe bacterial glycans
Bacterial cells are covered by a complex carbohydrate coat of armor that allows bacteria to thrive in a range of environme...
Chemical toolbox to interrogate Heparanase-1 activity
Chemical toolbox to interrogate Heparanase-1 activity
Heparanase-1 (HPSE-1), an endo-β-d-glucuronidase, is the only known enzyme that cleaves heparan sulfate (HS) [1,2]. The HP...
Fluorogenic polymethine dyes by intramolecular cyclization
Fluorogenic polymethine dyes by intramolecular cyclization
KeywordsFluorogenicityCarbocyaninesPolymethine dyesTurn-on probesIntramolecular cyclizationsSelf-labeling protein tagsSmal...