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Child Opportunity Index and clinical characteristics at diabetes diagnosis in youth: type 1 diabetes versus type 2 diabetes
WHAT IS ALREADY KNOWN ON THIS TOPICIndividual-level and neighborhood-level social determinants of health are increasingly ...
Genetic risk of type 2 diabetes modifies the association between lifestyle and glycemic health at 5 years postpartum among high-risk women
WHAT IS ALREADY KNOWN ON THIS TOPICWomen with gestational diabetes are at a 10-fold risk of developing type 2 diabetes.Hea...
Circulating metabolomic markers in association with overall burden of microvascular complications in type 1 diabetes
WHAT IS ALREADY KNOWN ON THIS TOPICSeveral circulating metabolites have been associated with the presence and progression ...
Role of kidney function on Nrf2 mRNA levels in type 2 diabetes
WHAT IS ALREADY KNOWN ON THIS TOPICHOW THIS STUDY MIGHT AFFECT RESEARCH, PRACTICE OR POLICYIntroductionDiabetic kidney dis...
Influence of diabetes and other risk factors on in-hospital mortality following kidney transplantation: an analysis of the Spanish National Hospital Discharge Database from 2016 to 2020
IntroductionDiabetes is one of the leading causes of end-stage renal disease, which results in a high risk of cardiovascul...
Gastric emptying during and following resolution of moderate diabetic ketoacidosis in type 1 diabetes: a case series
WHAT IS ALREADY KNOWN ON THIS TOPICHOW THIS STUDY MIGHT AFFECT RESEARCH, PRACTICE OR POLICYIntroductionGastroparesis, defi...
Characterization of the zebrafish as a model of ATP-sensitive potassium channel hyperinsulinism
IntroductionCongenital hyperinsulinism (HI) is the leading cause of persistent hypoglycemia in infants. Currently, more th...
A static glucose-stimulated insulin secretion (sGSIS) assay that is significantly predictive of time to diabetes reversal in the human islet bioassay
WHAT IS ALREADY KNOWN ON THIS TOPICHOW THIS STUDY MIGHT AFFECT RESEARCH, PRACTICE OR POLICYIntroductionThe last decades ha...
Pilot feasibility and efficacy of a strategy to sustain A1C improvement among diverse adults with type 2 diabetes completing a diabetes care management program
WHAT IS ALREADY KNOWN ON THIS TOPICSubstantial evidence exists supporting the positive impact of diabetes care management ...
Role of perirenal adiposity in renal dysfunction among CKD individuals with or without diabetes: a Japanese cross-sectional study
IntroductionDiabetes-related kidney changes often lead to chronic kidney disease (CKD), also known as diabetic kidney dise...
Cost-effectiveness analysis of two interventions to promote physical activity in a multiethnic population at high risk of diabetes: an economic evaluation of the 48-month PROPELS randomized controlled trial
WHAT IS ALREADY KNOWN ON THIS TOPICWHAT THIS STUDY ADDSWe found that neither intervention tested in PROPELS was cost-effec...
Landscape of pharmacogenetic variants associated with non-insulin antidiabetic drugs in the Indian population
IntroductionType 2 diabetes is epidemic in India, affecting over 101 million patients1 and recording the highest increase ...
Loneliness and the risk of type 2 diabetes
IntroductionLoneliness has been associated with adverse physical and psychological health outcomes such as depression and ...
Colonic epithelial hypoxia remains constant during the progression of diabetes in male UC Davis type 2 diabetes mellitus rats
WHAT IS ALREADY KNOWN ON THIS TOPICType 2 diabetes has been associated with an abnormal gut microbiota in several rodent m...
External validation and application of the Diabetes Population Risk Tool (DPoRT) for prediction of type 2 diabetes onset in the US population
IntroductionThe prevalence of diabetes has increased over the last several decades in all regions of the world.1 2 In the ...
Postprandial glucose variability and clusters of sex hormones, liver enzymes, and cardiometabolic factors in a South African cohort of African ancestry
WHAT IS ALREADY KNOWN ON THIS TOPICThere is high inter-individual variability in postprandial glucose (PPG) in response to...
Longitudinal changes in diet quality and food intake before and after diabetes awareness in American adults: the Coronary Artery Risk Development in Young Adults (CARDIA) study
IntroductionA high-quality plant-based diet with limited sweetened beverages during early life reduces the risk for gainin...
Variation in the relationship between fasting glucose and HbA1c: implications for the diagnosis of diabetes in different age and ethnic groups
WHAT IS ALREADY KNOWN ON THIS TOPICHOW THIS STUDY MIGHT AFFECT RESEARCH, PRACTICE, OR POLICYData indicate that HbA1c measu...
Greater persistence and adherence to basal insulin therapy is associated with lower healthcare utilization and medical costs in patients with type 2 diabetes: a retrospective database analysis
Plain language summarySome people with type 2 diabetes use insulin to manage their blood sugar, but many struggle to take ...
MicroRNA-5010-5p ameliorates high-glucose induced inflammation in renal tubular epithelial cells by modulating the expression of PPP2R2D
IntroductionChronic kidney disease (CKD) is a public health concern that affects approximately one-tenth of the global pop...
Omentin associates with serum metabolite profiles indicating lower diabetes risk: KORA F4 Study
WHAT IS ALREADY KNOWN ON THIS TOPICWHAT THIS STUDY ADDSSerum omentin levels associate with multiple metabolites, including...
Review of the direct and indirect effects of hyperglycemia on the HPA axis in T2DM and the co-occurrence of depression
IntroductionThe nervous, endocrine and immune systems work together to maintain physiological homeostasis during stress ch...
Predictive biomarkers of rapidly developing insulin deficiency in children with type 1 diabetes
IntroductionType 1 diabetes is caused by islet autoimmunity and declining insulin secretion. Environmental factors contrib...
Use of machine learning to identify characteristics associated with severe hypoglycemia in older adults with type 1 diabetes: a post-hoc analysis of a case-control study
IntroductionOlder adults with type 1 diabetes are a growing population within the USA.1 Although hypoglycemia is a concern...
Access to telehealth and changes in diabetes care patterns during the pandemic: evidence from a large integrated health system in the Southeast USA
IntroductionTo reduce the risk of diabetes-related complications including diabetic retinopathy, nephropathy, neuropathy, ...
Cancer risk according to fasting blood glucose trajectories: a population-based cohort study
IntroductionDiabetes represents an important problem for socioeconomic and public healthcare systems on a global scale, an...
Enhanced prediction of abnormal glucose tolerance using an extended non-invasive risk score incorporating routine renal biochemistry
WHAT IS ALREADY KNOWN ON THIS TOPICWHAT THIS STUDY ADDSType 2 diabetes can be prevented but a 75 g oral glucose tolerance ...
Racial differences in measures of glycemia in the Vitamin D and Type 2 Diabetes (D2d) Study: a secondary analysis of a randomized trial
WHAT IS ALREADY KNOWN ON THIS TOPICPrevious studies have found that the relationships between glucose and A1c vary between...
Association between lower extremity arterial calcification and coronary arterial calcification in a population at increased risk of cardiovascular disease
BackgroundArterial calcification in any arterial wall accounts for a threefold to fourfold increased risk of cardiovascula...
Burden of impaired awareness of hypoglycemia in people with diabetes undergoing hemodialysis
WHAT IS ALREADY KNOWN ON THIS TOPICLimited information exists regarding the occurrence of impaired awareness of hypoglycem...
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