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Neighborhood environment associations with cognitive function and structural brain measures in older African Americans
Neighborhood environment associations with cognitive function and structural brain measures in older African Americans
Since older adults spend significant time in their neighborhood environment, environmental factors such as neighborhood so...
Dystonia caused by ANO3 variants is due to attenuated Ca2+ influx by ORAI1
Dystonia caused by ANO3 variants is due to attenuated Ca2+ influx by ORAI1
Dystonia is a common neurological hyperkinetic movement disorder that can be caused by mutations in anoctamin 3 (ANO3, TME...
Understanding the dynamics driving obesity in socioeconomically deprived urban neighbourhoods: an expert-based systems map
Understanding the dynamics driving obesity in socioeconomically deprived urban neighbourhoods: an expert-based systems map
Over the past decades, the prevalence of obesity among adults has rapidly increased, particularly in socioeconomically dep...
Multimorbidity clusters and their associations with health-related quality of life in two UK cohorts
Multimorbidity clusters and their associations with health-related quality of life in two UK cohorts
Identifying clusters of multiple long-term conditions (MLTCs), also known as multimorbidity, and their associated burden m...
Association between pre-pregnancy maternal stress and small for gestational age: a population-based retrospective cohort study
Association between pre-pregnancy maternal stress and small for gestational age: a population-based retrospective cohort study
Maternal stress is a potential factor affecting fetal growth, but it is unknown whether it directly affects fetal growth r...
Investigating the causal effects of childhood and adulthood adiposity on later life mental health outcome: a Mendelian randomization study
Investigating the causal effects of childhood and adulthood adiposity on later life mental health outcome: a Mendelian randomization study
Obesity particularly during childhood is considered a global public health crisis and has been linked with later life heal...
Changes in sarcopenia and incident cardiovascular disease in prospective cohorts
Changes in sarcopenia and incident cardiovascular disease in prospective cohorts
Previous studies have identified sarcopenia as a significant risk factor for cardiovascular disease (CVD). However, these ...
Global, regional and national burden due to retinoblastoma in children aged younger than 10 years from 1990 to 2021
Global, regional and national burden due to retinoblastoma in children aged younger than 10 years from 1990 to 2021
Retinoblastoma (RB), an aggressive intraocular malignancy, significantly adds to the global disease burden in early childh...
Impaired pulmonary function increases the risk of gout: evidence from a large cohort study in the UK Biobank
Impaired pulmonary function increases the risk of gout: evidence from a large cohort study in the UK Biobank
Pulmonary function is increasingly recognized as a key factor in metabolic diseases. However, its link to gout risk remain...
A meta-analysis and systematic review of myocardial infarction-induced cardiomyocyte proliferation in adult mouse heart
A meta-analysis and systematic review of myocardial infarction-induced cardiomyocyte proliferation in adult mouse heart
The proliferation capacity of adult cardiomyocytes is very limited in the normal adult mammalian heart. Previous studies i...
Single-cell analysis reveals the loss of FABP4-positive proliferating valvular endothelial cells relates to functional mitral regurgitation
Single-cell analysis reveals the loss of FABP4-positive proliferating valvular endothelial cells relates to functional mitral regurgitation
Functional mitral regurgitation (MR) is a common form of mitral valve dysfunction that often persists even after surgical ...
The potential impact of inflammation on the lipid paradox in patients with acute myocardial infarction: a multicenter study
The potential impact of inflammation on the lipid paradox in patients with acute myocardial infarction: a multicenter study
Low-density lipoprotein cholesterol (LDL-C) is a well-recognized risk factor for cardiovascular diseases. However, several...
Risk of mortality between warfarin and direct oral anticoagulants: population-based cohort studies
Risk of mortality between warfarin and direct oral anticoagulants: population-based cohort studies
Direct oral anticoagulants (DOACs) have been reported to be associated with a higher risk of mortality compared with an ol...
Physiological measures variability and risks of heart disease and stroke: evidence from three cohort studies
Physiological measures variability and risks of heart disease and stroke: evidence from three cohort studies
The overall effect of long-term variability in physiological measures on cardiovascular health of older adults and the und...
The burden and clinical trajectory of immune checkpoint inhibitor-induced endocrinopathies: an 8-year experience
The burden and clinical trajectory of immune checkpoint inhibitor-induced endocrinopathies: an 8-year experience
Immune checkpoint inhibitors (ICIs) have revolutionized the management of cancer patients, but the emergence of ICI-relate...
Cognitive benefits of folic acid supplementation during pregnancy track with epigenetic changes at an imprint regulator
Cognitive benefits of folic acid supplementation during pregnancy track with epigenetic changes at an imprint regulator
The human ZFP57 gene is a major regulator of imprinted genes, maintaining DNA methylation marks that distinguish parent-of...
Clinical research framework proposal for ketogenic metabolic therapy in glioblastoma
Clinical research framework proposal for ketogenic metabolic therapy in glioblastoma
Glioblastoma (GBM) is the most aggressive primary brain tumor in adults, with a universally lethal prognosis despite maxim...
Efficacy of melatonin for prolonged disorders of consciousness: a double-blind, randomized clinical trial
Efficacy of melatonin for prolonged disorders of consciousness: a double-blind, randomized clinical trial
Sleep is essential for the recovery of patients with disorders of consciousness (DoC). However, few approaches targeting s...
Impact of HIV exposure without infection on hospital course and mortality among young children in sub-Saharan Africa: a multi-site cohort study
Impact of HIV exposure without infection on hospital course and mortality among young children in sub-Saharan Africa: a multi-site cohort study
Although mortality risk associated with HIV is well described, HIV-exposed uninfected (HEU) young children are also at inc...