SCI时时刷

search
CSF Aβ40 and P-tau181 might differentiate atypical from typical AD phenotypes: preliminary evidence
CSF Aβ40 and P-tau181 might differentiate atypical from typical AD phenotypes: preliminary evidence
Objectives. This study aimed at testing whether CSF levels of amyloid β42 (Aβ42), Aβ40, total tau and phosphorylated tau (...
Association between Gut Microbiota with Mild Cognitive Impairment and Alzheimer’s Disease in a Thai Population
Association between Gut Microbiota with Mild Cognitive Impairment and Alzheimer’s Disease in a Thai Population
Background: Mild cognitive impairment (MCI) and Alzheimer's disease (AD) are common in older adults. Much recent work ...
Frontostriatal circuits alterations associated with cognitive flexibility deterioration in Huntington's disease
Frontostriatal circuits alterations associated with cognitive flexibility deterioration in Huntington's disease
Background: Recent resting-state functional magnetic resonance imaging studies have reported abnormal functional connectiv...
Hippocampal Functional Connectivity in Parkinson’s Disease
Hippocampal Functional Connectivity in Parkinson’s Disease
Background: While the hippocampus is not part of the nigrostriatal dopaminergic pathway, influence of Parkinson’s Disease ...
Synaptic neurofilaments and GluN1-NfL interaction in experimental models of α-synucleinopathies
Synaptic neurofilaments and GluN1-NfL interaction in experimental models of α-synucleinopathies
Introduction: despite neurofilaments are mainly expressed in large caliber myelinated axons, recent evidence supports the ...
Clinical and molecular findings of intermediate allele carriers in the HTT gene from the Mexican Mestizo population
Clinical and molecular findings of intermediate allele carriers in the HTT gene from the Mexican Mestizo population
Introduction: There are reports of different clinical statuses in carriers of intermediate alleles (IAs) of CAG trinucleot...
Early Autonomic Symptoms Predict Functional Decline in Parkinson’s Disease Independent of Dopaminergic Therapy
Early Autonomic Symptoms Predict Functional Decline in Parkinson’s Disease Independent of Dopaminergic Therapy
Introduction: Parkinson’s disease (PD) has variable progression; identifying determinants of functional decline in PD is n...
Heart Rate Variability in Huntington Disease. 
A Long Term Longitudinal Study
Heart Rate Variability in Huntington Disease. A Long Term Longitudinal Study
Introduction: The aim of the study was to follow tonic and phasic autonomic nervous activity in Huntington disease (HD) mu...
Diagnostic accuracy of noun- and verb-naming tasks in detecting cognitive impairment in Parkinson’s disease
Diagnostic accuracy of noun- and verb-naming tasks in detecting cognitive impairment in Parkinson’s disease
Background. In Parkinson’s disease (PD), verb-naming tasks have been proposed as superior to noun-naming ones in detecting...
Juvenile-Onset Kufs Disease in a Chinese Consanguineous Family due to CLN6 Mutation
Juvenile-Onset Kufs Disease in a Chinese Consanguineous Family due to CLN6 Mutation
Objective: To identify the genetic cause of two cases of Kufs disease in the same family. The two affected individuals exh...
Distribution Changes of Neural Precursor Cells in the Brain Stem of Tg(SOD1*G93A)1Gur Mice
Distribution Changes of Neural Precursor Cells in the Brain Stem of Tg(SOD1*G93A)1Gur Mice
Objectives: The alteration of vimentin-containing cells (VCCs) proliferation, differentiation and migration in the brain s...
Plasma Cystatin C correlates with plasma NfL levels and predicts disease progression in Parkinson’s disease
Plasma Cystatin C correlates with plasma NfL levels and predicts disease progression in Parkinson’s disease
Introduction: Previous studies reported increased plasma levels of Cystatin C (Cys-C) in Parkinson’s disease (PD) and clai...
Neuroprotective and therapeutic effects of Tocovid and Twendee-X on Aβ oligomers-induced damage in the SH-SY5Y cell line
Neuroprotective and therapeutic effects of Tocovid and Twendee-X on Aβ oligomers-induced damage in the SH-SY5Y cell line
Background: Alzheimer’s disease (AD) is the most frequent cause of dementia among the elderly. The accumulation of amyloid...
Inflammatory cytokine levels in patients with sporadic amyotrophic lateral sclerosis
Inflammatory cytokine levels in patients with sporadic amyotrophic lateral sclerosis
Objectives In the present study, inflammatory factors, including interleukin (IL) and tumor necrosis factor-α (TNF-α) in ...
Sexuality and neurodegenerative disease: An unmet challenge for patients, care-givers and treatment.
Sexuality and neurodegenerative disease: An unmet challenge for patients, care-givers and treatment.
Background: Many factors affect sexuality in the elderly such as dementia which is a common cause of inappropriate sexual...
Cancer in Parkinson’s Disease: An Approximation to the Main Risk Factors
Cancer in Parkinson’s Disease: An Approximation to the Main Risk Factors
<b><i>Background:</i></b> Many evidences suggest a pathological link between neurodegenerative dis...
Increased intake of fast acting carbohydrates in patients with Parkinson’s Disease
Increased intake of fast acting carbohydrates in patients with Parkinson’s Disease
Background: Patients with Parkinson’s Disease (PD) regularly report an increased desire for food or beverages with high su...
Heart Rate Variability during wake and sleep in Huntington’s Disease patients. An observational, cross-sectional, cohort study.
Heart Rate Variability during wake and sleep in Huntington’s Disease patients. An observational, cross-sectional, cohort study.
Introduction Autonomic dysfunction has been reported as one of non-motor manifestations of both pre-symptomatic and manife...
Tit for tat: costly punishment in manifest Huntington’s disease
Tit for tat: costly punishment in manifest Huntington’s disease
Objective: We aimed to investigate costly punishment in patients with HD. Background: Huntington’s disease (HD) is an aut...
Cerebrospinal fluid levels of 5-hydroxyindoleacetic acid in Parkinson’s disease and atypical parkinsonian syndromes
Cerebrospinal fluid levels of 5-hydroxyindoleacetic acid in Parkinson’s disease and atypical parkinsonian syndromes
Background: Various cerebrospinal fluid (CSF) biomarkers are studied in Parkinson’s disease (PD) and atypical parkinsonian...
Cancer in Parkinson Disease: an approximation to the main risk factors
Cancer in Parkinson Disease: an approximation to the main risk factors
Abstract Background: Many evidences suggest a pathological link between neurodegenerative diseases and cancer. In fact, se...