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Advanced biomanufacturing and evaluation of adeno-associated virus
Advanced biomanufacturing and evaluation of adeno-associated virus
Recombinant adeno-associated virus (rAAV) has been developed as a safe and effective gene delivery vehicle to treat rare g...
The progressive trend of modeling and drug screening systems of breast cancer bone metastasis
The progressive trend of modeling and drug screening systems of breast cancer bone metastasis
Bone metastasis is considered as a considerable challenge for breast cancer patients. Various in vitro and in vivo models ...
Kinematic movement and balance parameter analysis in neurological gait disorders
Kinematic movement and balance parameter analysis in neurological gait disorders
Neurological gait disorders are mainly classified based on clinical observation, and therefore difficult to objectify or q...
An engineered ligand-responsive Csy4 endoribonuclease controls transgene expression from Sendai virus vectors
An engineered ligand-responsive Csy4 endoribonuclease controls transgene expression from Sendai virus vectors
Viral vectors are attractive gene delivery vehicles because of their broad tropism, high transduction efficiency, and dura...
Tissue engineering RPE sheet derived from hiPSC-RPE cell spheroids supplemented with Y-27632 and RepSox
Tissue engineering RPE sheet derived from hiPSC-RPE cell spheroids supplemented with Y-27632 and RepSox
Retinal pigment epithelium (RPE) cell therapy is a promising way to treat many retinal diseases. However, obtaining transp...
Stable, neuron-specific gene expression in the mouse brain
Stable, neuron-specific gene expression in the mouse brain
Gene delivery to, and expression in, the mouse brain is important for understanding gene functions in brain development an...
An ovalbumin fusion strategy to increase recombinant protein secretion in chicken eggs
An ovalbumin fusion strategy to increase recombinant protein secretion in chicken eggs
Maternal secretion of recombinant proteins into chicken eggs may provide a viable approach for pharmaceutical production b...
Optimization of a recombinant BlaR-CTD protein formulation using the response surface methodology
Optimization of a recombinant BlaR-CTD protein formulation using the response surface methodology
The sequence of a carboxy-terminal of the β-lactam sensor-transducer protein (BlaR-CTD) from Bacillus licheniformis A...
3D-printed PCL@BG scaffold integrated with SDF-1α-loaded hydrogel for enhancing local treatment of bone defects
3D-printed PCL@BG scaffold integrated with SDF-1α-loaded hydrogel for enhancing local treatment of bone defects
The long-term nonunion of bone defects is always a difficult problem in orthopaedics treatment. Artificial bone implants m...
3D printed zirconia used as dental materials: a critical review
3D printed zirconia used as dental materials: a critical review
In view of its high mechanical performance, outstanding aesthetic qualities, and biological stability, zirconia has been w...
Microfluidic device for enhancement and analysis of osteoblast differentiation in three-dimensional cell cultures
Microfluidic device for enhancement and analysis of osteoblast differentiation in three-dimensional cell cultures
Three-dimensional (3D) cell cultures are to date the gold standard in biomedical research fields due to their enhanced bio...
Challenges and progress of neurodrug: bioactivities, production and delivery strategies of nerve growth factor protein
Challenges and progress of neurodrug: bioactivities, production and delivery strategies of nerve growth factor protein
Nerve growth factor (NGF) is a vital cytokine that plays a crucial role in the development and regeneration of the nervous...
Research progress of biomimetic materials in oral medicine
Research progress of biomimetic materials in oral medicine
Biomimetic materials are able to mimic the structure and functional properties of native tissues especially natural oral t...
Preparation and in vitro evaluation of biological agents based on Zinc-laponite- curcumin incorporated in alginate hydrogel
Preparation and in vitro evaluation of biological agents based on Zinc-laponite- curcumin incorporated in alginate hydrogel
Due to their outstanding structures and properties, three-dimensional (3D) hydrogels and nanoparticles have been widely st...
Antler stem cell-derived exosomes promote regenerative wound healing via fibroblast-to-myofibroblast transition inhibition
Antler stem cell-derived exosomes promote regenerative wound healing via fibroblast-to-myofibroblast transition inhibition
The typical outcome of mammalian wound healing is scarring, a fibrotic process mediated by myofibroblast aggregation. Perf...
Engineered live bacteria as disease detection and diagnosis tools
Engineered live bacteria as disease detection and diagnosis tools
Sensitive and minimally invasive medical diagnostics are essential to the early detection of diseases, monitoring their pr...
Novel ultra-stretchable and self-healing crosslinked poly (ethylene oxide)-cationic guar gum hydrogel
Novel ultra-stretchable and self-healing crosslinked poly (ethylene oxide)-cationic guar gum hydrogel
Hydrogels are three-dimensional structures with specific features that render them useful for biomedical applications, suc...
The lyophilized chloroplasts store synthetic DARPin G3 as bioactive encapsulated organelles
The lyophilized chloroplasts store synthetic DARPin G3 as bioactive encapsulated organelles
The high cost of fermentation, purification, cold storage and transportation, short shelf life, and sterile delivery metho...