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Influence of shear force on ex vivo expansion of hematopoietic model cells in a stirred tank bioreactor
Influence of shear force on ex vivo expansion of hematopoietic model cells in a stirred tank bioreactor
To evaluate shear stress influence on ex vivo expansion of hematopoietic cell lineages for clinical application, in this s...
Development of a universal, oriented antibody immobilization method to functionalize vascular prostheses for enhanced endothelialization for potential clinical application
Development of a universal, oriented antibody immobilization method to functionalize vascular prostheses for enhanced endothelialization for potential clinical application
Thrombosis is a common cause of vascular prosthesis failure. Antibody coating of prostheses to capture circulating endothe...
Culture of vibrating microtome tissue slices as a 3D model in biomedical research
Culture of vibrating microtome tissue slices as a 3D model in biomedical research
The basic idea behind the use of 3-dimensional (3D) tools in biomedical research is the assumption that the structures und...
Enhancing chemical and physical stability of pharmaceuticals using freeze-thaw method: challenges and opportunities for process optimization through quality by design approach
Enhancing chemical and physical stability of pharmaceuticals using freeze-thaw method: challenges and opportunities for process optimization through quality by design approach
The freeze-thaw (F/T) method is commonly employed during the processing and handling of drug substances to enhance their c...
A CRISPR interference strategy for gene expression silencing in multiple myeloma cell lines
A CRISPR interference strategy for gene expression silencing in multiple myeloma cell lines
Multiple myeloma (MM) is the second most common hematologic neoplasm which is characterized by proliferation and infiltrat...
Non-spherical gold nanoparticles enhanced fluorescence of carbon dots for norovirus-like particles detection
Non-spherical gold nanoparticles enhanced fluorescence of carbon dots for norovirus-like particles detection
Norovirus is a common pathogen that causes foodborne outbreaks every year and the increasing number of deaths caused by it...
Novel organoid construction strategy for non-involuting congenital hemangioma for drug validation
Novel organoid construction strategy for non-involuting congenital hemangioma for drug validation
Non-involuting congenital hemangiomas (NICHs) are fully formed vascular tumors at birth with distinctive clinical, radiolo...
Experimental studies from shake flasks to 3 L stirred tank bioreactor of nutrients and oxygen supply conditions to improve the growth of the avian cell line DuckCelt®-T17
Experimental studies from shake flasks to 3 L stirred tank bioreactor of nutrients and oxygen supply conditions to improve the growth of the avian cell line DuckCelt®-T17
To produce viral vaccines, avian cell lines are interesting alternatives to replace the egg-derived processes for viruses ...
Development of anti-aflatoxin B1 nanobodies from a novel mutagenesis-derived synthetic library for traditional Chinese medicine and foods safety testing
Development of anti-aflatoxin B1 nanobodies from a novel mutagenesis-derived synthetic library for traditional Chinese medicine and foods safety testing
The main commercially available methods for detecting small molecules of mycotoxins in traditional Chinese medicine (TCM) ...
Targeting the PEDV 3CL protease for identification of small molecule inhibitors: an insight from virtual screening, ADMET prediction, molecular dynamics, free energy landscape, and binding energy calculations
Targeting the PEDV 3CL protease for identification of small molecule inhibitors: an insight from virtual screening, ADMET prediction, molecular dynamics, free energy landscape, and binding energy calculations
The porcine epidemic diarrhea virus (PEDV) represents a major health issue for piglets worldwide and does significant dama...
Automated classification of urine biomarkers to diagnose pancreatic cancer using 1-D convolutional neural networks
Automated classification of urine biomarkers to diagnose pancreatic cancer using 1-D convolutional neural networks
Early diagnosis of Pancreatic Ductal Adenocarcinoma (PDAC) is the main key to surviving cancer patients. Urine proteomic b...
An efficient method for cell sheet bioengineering from rBMSCs on thermo-responsive PCL-PEG-PCL copolymer
An efficient method for cell sheet bioengineering from rBMSCs on thermo-responsive PCL-PEG-PCL copolymer
Utilizing both medium enrichment and a thermos-responsive substrate to maintain the cell-to-cell junctions and extracellul...
Melatonin and endothelial cell-loaded alginate-fibrin hydrogel promoted angiogenesis in rat cryopreserved/thawed ovaries transplanted to the heterotopic sites
Melatonin and endothelial cell-loaded alginate-fibrin hydrogel promoted angiogenesis in rat cryopreserved/thawed ovaries transplanted to the heterotopic sites
Ischemic niche can promote follicular atresia following the transplantation of cryopreserved/thawed ovaries to the heterot...
Unravelling the mechanotransduction pathways in Alzheimer’s disease
Unravelling the mechanotransduction pathways in Alzheimer’s disease
Alzheimer’s disease (AD) represents one of the most common and debilitating neurodegenerative disorders. By the end ...
Early introduction of 3D modeling modules promotes the development of simulation skills in downstream biomedical engineering curricula
Early introduction of 3D modeling modules promotes the development of simulation skills in downstream biomedical engineering curricula
Recent advancements in additive manufacturing have made 3D design a desirable skill in combating the historically slow dev...
Rapid, simple, and effective strategy to produce monoclonal antibodies targeting protein structures using hybridoma technology
Rapid, simple, and effective strategy to produce monoclonal antibodies targeting protein structures using hybridoma technology
Monoclonal antibodies are essential in life science research and developing antibody drugs and test drugs. Various methods...
An in vitro culture platform for studying the effect of collective cell migration on spatial self-organization within induced pluripotent stem cell colonies
An in vitro culture platform for studying the effect of collective cell migration on spatial self-organization within induced pluripotent stem cell colonies
Human induced pluripotent stem cells (hiPSCs) provide an in vitro system to identify the impact of cell behavior on the ea...
Recent advances in modified poly (lactic acid) as tissue engineering materials
Recent advances in modified poly (lactic acid) as tissue engineering materials
As an emerging science, tissue engineering and regenerative medicine focus on developing materials to replace, restore or ...
Antioxidant activities in relation to the transport of heavy metals from the soil to different parts of Betula pendula (Roth.)
Antioxidant activities in relation to the transport of heavy metals from the soil to different parts of Betula pendula (Roth.)
Birch is a tree with a common occurrence in the environment and its organs are used in the form of herbal material. An imp...
Multilayered blow-spun vascular prostheses with luminal surfaces in Nano/Micro range: the influence on endothelial cell and platelet adhesion
Multilayered blow-spun vascular prostheses with luminal surfaces in Nano/Micro range: the influence on endothelial cell and platelet adhesion
In this study, two types of polyurethane-based cylindrical multilayered grafts with internal diameters ≤ ...
Dynamic interaction of injected liquid jet with skin layer interfaces revealed by microsecond imaging of optically cleared ex vivo skin tissue model
Dynamic interaction of injected liquid jet with skin layer interfaces revealed by microsecond imaging of optically cleared ex vivo skin tissue model
Needle-free jet injection (NFJI) systems enable a controlled and targeted delivery of drugs into skin tissue. However, a s...
Customized biofilm device for antibiofilm and antibacterial screening of newly developed nanostructured silver and zinc coatings
Customized biofilm device for antibiofilm and antibacterial screening of newly developed nanostructured silver and zinc coatings
Bacterial colonisation on implantable device surfaces is estimated to cause more than half of healthcare-associated infect...
Exosome-mediated crosstalk between epithelial cells amplifies the cell injury cascade in CaOx stone formation
Exosome-mediated crosstalk between epithelial cells amplifies the cell injury cascade in CaOx stone formation
Calcium oxalate (CaOx) stone disease is found worldwide. To explore the role of exosomes as a mediator of intercellular cr...
Prospective use of amniotic mesenchymal stem cell metabolite products for tissue regeneration
Prospective use of amniotic mesenchymal stem cell metabolite products for tissue regeneration
Chronic disease can cause tissue and organ damage constituting the largest obstacle to therapy which, in turn, reduces pat...
Assessing the capabilities of 2D fluorescence monitoring in microtiter plates with data-driven modeling for secondary substrate limitation experiments of Hansenula polymorpha
Assessing the capabilities of 2D fluorescence monitoring in microtiter plates with data-driven modeling for secondary substrate limitation experiments of Hansenula polymorpha
Non-invasive online fluorescence monitoring in high-throughput microbioreactors is a well-established method to accelerate...
Therapeutic angiogenesis and tissue revascularization in ischemic vascular disease
Therapeutic angiogenesis and tissue revascularization in ischemic vascular disease
Ischemic vascular disease is a major healthcare problem. The keys to treatment lie in vascular regeneration and restoratio...
LIFTOSCOPE: development of an automated AI-based module for time-effective and contactless analysis and isolation of cells in microtiter plates
LIFTOSCOPE: development of an automated AI-based module for time-effective and contactless analysis and isolation of cells in microtiter plates
The cultivation, analysis, and isolation of single cells or cell cultures are fundamental to modern biological and medical...
CD146 expression profile in human skin and pre-vascularized dermo-epidermal skin substitutes in vivo
CD146 expression profile in human skin and pre-vascularized dermo-epidermal skin substitutes in vivo
CD146 is a cell adhesion molecule whose expression profile in human skin has not yet been elucidated. Here, we characteriz...
Research progress on black phosphorus hybrids hydrogel platforms for biomedical applications
Research progress on black phosphorus hybrids hydrogel platforms for biomedical applications
Hydrogels, also known as three-dimensional, flexible, and polymer networks, are composed of natural and/or synthetic polym...
RN-Autoencoder: Reduced Noise Autoencoder for classifying imbalanced cancer genomic data
RN-Autoencoder: Reduced Noise Autoencoder for classifying imbalanced cancer genomic data
In the current genomic era, gene expression datasets have become one of the main tools utilized in cancer classification. ...
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