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APOL1 nephropathy – a population genetics success story
APOL1 nephropathy – a population genetics success story
Purpose of review More than a decade ago, apolipoprotein L1 (APOL1) risk alleles designated G1 an
Phosphate sensing in health and disease
Phosphate sensing in health and disease
Purpose of review Disruptions of phosphate homeostasis are associated with a multitude of disease
New therapeutic perspectives for vascular and valvular calcifications in chronic kidney disease
New therapeutic perspectives for vascular and valvular calcifications in chronic kidney disease
Purpose of review Vascular and valvular calcification are associated with cardiovascular morbidit
Mitochondrial bioenergetics: coupling of transport to tubular mitochondrial metabolism
Mitochondrial bioenergetics: coupling of transport to tubular mitochondrial metabolism
Purpose of review Renal tubules have robust active transport and mitochondrial metabolism, which
New tools to study renal fibrogenesis
New tools to study renal fibrogenesis
Purpose of review Kidney fibrosis is a key pathological aspect and outcome of chronic kidney dise
The role of hypoxia in chronic kidney disease: a nuanced perspective
The role of hypoxia in chronic kidney disease: a nuanced perspective
Purpose of review This review critically examines the role of hypoxia in chronic kidney disease (
A molecular journey on the pathogenesis of primary hyperoxaluria
A molecular journey on the pathogenesis of primary hyperoxaluria
Purpose of review Primary hyperoxalurias (PHs) are rare disorders caused by the deficit of liver
Thiazides for kidney stone recurrence prevention
Thiazides for kidney stone recurrence prevention
Purpose of review Kidney stones are the most common condition affecting the kidney, and character
Lysine and salt-sensitive hypertension
Lysine and salt-sensitive hypertension
Purpose of review Salt-sensitive (SS) hypertension and its associated kidney damage have been ext
Skeletal parathyroid hormone hyporesponsiveness: a neglected, but clinically relevant reality in chronic kidney disease
Skeletal parathyroid hormone hyporesponsiveness: a neglected, but clinically relevant reality in chronic kidney disease
Purpose of review Defining the optimal parathyroid hormone (PTH) target in chronic kidney disease
Integrating the patient voice: patient-centred and equitable clinical risk prediction for kidney health and disease
Integrating the patient voice: patient-centred and equitable clinical risk prediction for kidney health and disease
Purpose of review Personalized approaches to care are increasingly common in clinical nephrology.
Fibroblast growth factor 23 is pumping iron: C-terminal-fibroblast growth factor 23 cleaved peptide and its function in iron metabolism
Fibroblast growth factor 23 is pumping iron: C-terminal-fibroblast growth factor 23 cleaved peptide and its function in iron metabolism
Purpose of review Iron deficiency regulates the production of the bone-derived phosphaturic hormo
New insights into renal calcium-sensing receptor activation
New insights into renal calcium-sensing receptor activation
Purpose of review Activation of the calcium-sensing receptor (CASR) in the parathyroid gland supp
Rare genetic disorders that impair parathyroid hormone synthesis, secretion, or bioactivity provide insights into the diagnostic utility of different parathyroid hormone assays
Rare genetic disorders that impair parathyroid hormone synthesis, secretion, or bioactivity provide insights into the diagnostic utility of different parathyroid hormone assays
Purpose of review Parathyroid hormone (PTH) is the major peptide hormone regulator of blood calci
New guidelines and therapeutic updates for the management of lupus nephritis
New guidelines and therapeutic updates for the management of lupus nephritis
Purpose of review Systemic lupus erythematosus (SLE) can be a devastating condition, striking you
Novel indications for referral and care for simultaneous liver kidney transplant recipients
Novel indications for referral and care for simultaneous liver kidney transplant recipients
Purpose of review Kidney dysfunction is challenging in liver transplant candidates to determine w
Deep learning applications for kidney histology analysis
Deep learning applications for kidney histology analysis
Purpose of review Nephropathology is increasingly incorporating computational methods to enhance
IgA vasculitis nephritis: insights from kidney biopsies
IgA vasculitis nephritis: insights from kidney biopsies
Purpose of review To present findings indicating the value of kidney biopsy in assessing prognosi
Biopsy-based transcriptomics in the diagnosis of kidney transplant rejection
Biopsy-based transcriptomics in the diagnosis of kidney transplant rejection
Purpose of review The last year has seen considerable progress in translational research explorin
New therapies for immunoglobulin A nephropathy: what's the standard of care in 2023?
New therapies for immunoglobulin A nephropathy: what's the standard of care in 2023?
Purpose of review As the most common primary glomerulonephritis, immunoglobulin A (IgA) nephropat
Has the time come for age-adapted glomerular filtration rate criteria to define chronic kidney disease: how soon is now?
Has the time come for age-adapted glomerular filtration rate criteria to define chronic kidney disease: how soon is now?
Purpose of review The conventional definition of chronic kidney disease (CKD) primarily relies on
Emerging evidence for glucagon-like peptide-1 agonists in slowing chronic kidney disease progression
Emerging evidence for glucagon-like peptide-1 agonists in slowing chronic kidney disease progression
Purpose of review Diabetic kidney disease continues to increase, and several novel therapeutic ag
Cystatin C should be routinely available for estimating kidney function
Cystatin C should be routinely available for estimating kidney function
Purpose of review In this report, we summarize why the availability of cystatin C is important ac
A basic solution for a complex problem: does treatment of metabolic acidosis slow CKD progression?
A basic solution for a complex problem: does treatment of metabolic acidosis slow CKD progression?
Purpose of this review Metabolic acidosis is frequently encountered in patients with chronic kidn
Prediction models for earlier stages of chronic kidney disease
Prediction models for earlier stages of chronic kidney disease
Purpose of review Identifying patients with risk of developing progressive chronic kidney disease
Alport syndrome and Alport kidney diseases – elucidating the disease spectrum
Alport syndrome and Alport kidney diseases – elucidating the disease spectrum
Purpose of review With the latest classification, variants in three collagen IV genes, COL4A3, CO
The genetics of cystinuria – an update and critical reevaluation
The genetics of cystinuria – an update and critical reevaluation
Purpose of review We aimed to critically evaluate how the establishment of genotype-based treatme
Predictive models in chronic kidney disease: essential tools in clinical practice
Predictive models in chronic kidney disease: essential tools in clinical practice
Purpose of review The integration of risk prediction in managing chronic kidney disease (CKD) is
Let's stop talking about ‘citrate toxicity’
Let's stop talking about ‘citrate toxicity’
Purpose of review Continuous renal replacement therapy (CRRT) is a vital medical intervention use
Kidney function assessment in the geriatric population
Kidney function assessment in the geriatric population
Purpose of review Kidney function declines with normal aging. But it also declines with the progr
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