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Optimising management of moderate secondary mitral regurgitation: insights into pharmacological and interventional approaches
Optimising management of moderate secondary mitral regurgitation: insights into pharmacological and interventional approaches
Secondary mitral regurgitation (SMR) is a complex and evolving challenge in the landscape of heart failure (HF) management...
Correction: The efficacy of extraembryonic stem cells in improving blood flow within animal models of lower limb ischaemia
Correction: The efficacy of extraembryonic stem cells in improving blood flow within animal models of lower limb ischaemia
Mohamed Omer S, Krishna SM, Li J, et al. The efficacy of extraembryonic stem cells in improving blood flow within animal m...
Diagnostic accuracy of non-invasive cardiac imaging modalities in patients with a history of coronary artery disease: a meta-analysis
Diagnostic accuracy of non-invasive cardiac imaging modalities in patients with a history of coronary artery disease: a meta-analysis
WHAT IS ALREADY KNOWN ON THIS TOPICThe diagnostic performance of various non-invasive imaging techniques for detecting cor...
Effects of resveratrol on aortic growth in patients with Marfan syndrome: a single-arm open-label multicentre trial
Effects of resveratrol on aortic growth in patients with Marfan syndrome: a single-arm open-label multicentre trial
IntroductionMarfan syndrome (MFS) is an inherited connective tissue disorder caused almost exclusively by mutations in the...
Unresponsive patient with bradycardia
Unresponsive patient with bradycardia
A patient in their 60s, with a background of asthma and seizures from alcohol withdrawal was brought in via ambulance to t...
Advancing the access to cardiovascular diagnosis and treatment among women with cardiovascular disease: a joint British Cardiovascular Societies consensus document
Advancing the access to cardiovascular diagnosis and treatment among women with cardiovascular disease: a joint British Cardiovascular Societies consensus document
IntroductionGlobally, cardiovascular disease (CVD) is the leading cause of death in women.1 However, the misconception tha...
Percutaneous revascularisation in chronic coronary syndromes: when real-world data unveil the other side of the coin
Percutaneous revascularisation in chronic coronary syndromes: when real-world data unveil the other side of the coin
The optimal treatment of chronic coronary syndromes (CCS) represents to date a matter of debate as revascularisation has n...
Advancing womens cardiovascular health: an international lens on the Joint British Cardiovascular Societies consensus statement
Advancing womens cardiovascular health: an international lens on the Joint British Cardiovascular Societies consensus statement
Cardiovascular disease (CVD) remains the leading cause of death and disability for women and men worldwide. In 2021, 30% o...
Management of bicuspid aortic valve disease in the transcatheter aortic valve implantation era
Management of bicuspid aortic valve disease in the transcatheter aortic valve implantation era
In an era of rapidly expanding use of transcatheter aortic valve implantation (TAVI), the management of patients with bicu...
Management strategies and outcomes in pregnancy-related acute aortic dissection: a multicentre cohort study in China
Management strategies and outcomes in pregnancy-related acute aortic dissection: a multicentre cohort study in China
IntroductionAcute aortic dissection (AD) is a rare catastrophic cardiovascular disease but has high morbidity and mortalit...
Granulocyte colony-stimulating factor for stem cell mobilisation in acute myocardial infarction: a randomised controlled trial
Granulocyte colony-stimulating factor for stem cell mobilisation in acute myocardial infarction: a randomised controlled trial
WHAT IS ALREADY KNOWN ON THIS TOPICIn previous studies, we showed that early administration of granulocyte colony-stimulat...
Percutaneous coronary intervention plus medical therapy versus medical therapy alone in chronic coronary syndrome: a propensity score-matched analysis from the Swedish Coronary Angiography and Angioplasty Registry
Percutaneous coronary intervention plus medical therapy versus medical therapy alone in chronic coronary syndrome: a propensity score-matched analysis from the Swedish Coronary Angiography and Angioplasty Registry
WHAT IS ALREADY KNOWN ON THIS TOPICPrevious studies have shown that percutaneous coronary intervention (PCI) improves symp...
Diagnosis and management of resistant hypertension
Diagnosis and management of resistant hypertension
Resistant hypertension is a condition where blood pressure levels remain elevated above target despite changes in lifestyl...
Health, burnout and well-being of UK cardiology trainees: insights from the British Junior Cardiologists Association Survey
Health, burnout and well-being of UK cardiology trainees: insights from the British Junior Cardiologists Association Survey
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Response to: Correspondence on 'Long-term prognosis of low high-sensitivity cardiac troponin T in the emergency department compared with the general population by Sikandari et al
Response to: Correspondence on 'Long-term prognosis of low high-sensitivity cardiac troponin T in the emergency department compared with the general population by Sikandari et al
We thank Sikandari et al for their comments regarding the long-term prognosis of patients with chest pain who present in t...
Correspondence on 'Long-term prognosis of low high-sensitivity cardiac troponin T in the emergency department compared with the general population by Cyon et al
Correspondence on 'Long-term prognosis of low high-sensitivity cardiac troponin T in the emergency department compared with the general population by Cyon et al
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Decoding proteins in cardiometabolic disease: the power and challenges of proteomics
Decoding proteins in cardiometabolic disease: the power and challenges of proteomics
Circulating proteins are the result of genetically inherited predispositions to diseases and the influences of environment...
Universal definition of myocardial infarction: what must we know? What is next?
Universal definition of myocardial infarction: what must we know? What is next?
In the beginning of the 20th century, the first reports of the clinical manifestations of myocardial infarction (MI) appea...
Treating iron deficiency in patients with heart failure: what, why, when, how, where and who
Treating iron deficiency in patients with heart failure: what, why, when, how, where and who
I keep six honest serving-men(They taught me all I knew);Their names are What and Why and When and How and Where and Who.-...
A rare case of atrial flutter and a cystic mass in the left atrium
A rare case of atrial flutter and a cystic mass in the left atrium
Clinical introductionA woman is her 60s with no medical history presented to the hospital with palpitations and occasional...
Associations between circulating proteins and cardiometabolic diseases: a systematic review and meta-analysis of observational and Mendelian randomisation studies
Associations between circulating proteins and cardiometabolic diseases: a systematic review and meta-analysis of observational and Mendelian randomisation studies
The overview of analytical approaches and key findings were presented in figure 1. The literature search generated 14 932 ...
Emerging role of incretin-based therapy as first-line antihypertensives in obesity
Emerging role of incretin-based therapy as first-line antihypertensives in obesity
Obesity is a major global health issue and a leading cause of premature death. The prevalence of obesity has been rising f...
From urinary proteomic signature to individualised pharmacotherapy
From urinary proteomic signature to individualised pharmacotherapy
As the number of patients suffering from heart failure is constantly rising worldwide, optimised medical treatment is indi...
Circulating biomarkers of myocardial remodelling: current developments and clinical applications
Circulating biomarkers of myocardial remodelling: current developments and clinical applications
Myocardial remodelling, entailing cellular and molecular changes in the different components of the cardiac tissue in resp...
Too fast, too furious
Too fast, too furious
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Tirzepatide and blood pressure reduction: stratified analyses of the SURMOUNT-1 randomised controlled trial
Tirzepatide and blood pressure reduction: stratified analyses of the SURMOUNT-1 randomised controlled trial
IntroductionHypertension persists as a leading contributor to global disability and premature death. The Global Burden of ...
Urinary proteomic signature of mineralocorticoid receptor antagonism by spironolactone: evidence from the HOMAGE trial
Urinary proteomic signature of mineralocorticoid receptor antagonism by spironolactone: evidence from the HOMAGE trial
WHAT IS ALREADY KNOWN ON THIS TOPICSpironolactone reduces plasma markers reflecting collagen-1 synthesis and decreases myo...
Differential effects of balloon pulmonary angioplasty on chronic thromboembolic pulmonary disease
Differential effects of balloon pulmonary angioplasty on chronic thromboembolic pulmonary disease
IntroductionIn recent years, the treatment of chronic thromboembolic pulmonary hypertension (CTEPH) has seen remarkable pr...
Pulmonary arterial hypertension in congenital heart disease
Pulmonary arterial hypertension in congenital heart disease
LEARNING OBJECTIVESReview the diagnostic pathway for pulmonary arterial hypertension (PAH) in congenital heart disease (CH...
Age-stratified patterns in clinical presentation, treatment and outcomes in acute pericarditis: a retrospective cohort study
Age-stratified patterns in clinical presentation, treatment and outcomes in acute pericarditis: a retrospective cohort study
WHAT IS ALREADY KNOWN ON THIS TOPICWHAT THIS STUDY ADDSThe study emphasises the crucial role of age in the clinical presen...
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