SCI时时刷

search
+
Survival differences between patients with de novo and relapsed/progressed advanced non-small cell lung cancer without epidermal growth factor receptor mutations or anaplastic lymphoma kinase rearrangements
Survival differences between patients with de novo and relapsed/progressed advanced non-small cell lung cancer without epidermal growth factor receptor mutations or anaplastic lymphoma kinase rearrangements
We aimed to examine whether patients with de novo and relapsed/progressed stage IIIB–IV non-small cell lung cancer (...
CYD0281, a Bcl-2 BH4 domain antagonist, inhibits tumor angiogenesis and breast cancer tumor growth
CYD0281, a Bcl-2 BH4 domain antagonist, inhibits tumor angiogenesis and breast cancer tumor growth
B-cell lymphoma 2 (Bcl-2) family proteins are key regulators of apoptosis, which possess four conserved Bcl-2 homologies (...
Clinical research of the value of high-risk CTV setting on intensity-modulated radiotherapy for stage IIB-IVA cervical cancer
Clinical research of the value of high-risk CTV setting on intensity-modulated radiotherapy for stage IIB-IVA cervical cancer
This study aims to evaluate the clinical efficacy and side effects of setting up a high-risk clinical target volu...
ATF2 loss promotes 5-FU resistance in colon cancer cells via activation of the ATR-Chk1 damage response pathway
ATF2 loss promotes 5-FU resistance in colon cancer cells via activation of the ATR-Chk1 damage response pathway
The role of ATF2 in colon cancer (CC) is controversial. Recently, we reported that low ATF2 expression is characteristic o...
ARL4C is associated with epithelial-to-mesenchymal transition in colorectal cancer
ARL4C is associated with epithelial-to-mesenchymal transition in colorectal cancer
ADP-ribosylation factor-like protein 4 C (ARL4C) is a member of the ARF small GTP-binding protein subfamily. The ...
CT radiomics features of meso-esophageal fat in predicting overall survival of patients with locally advanced esophageal squamous cell carcinoma treated by definitive chemoradiotherapy
CT radiomics features of meso-esophageal fat in predicting overall survival of patients with locally advanced esophageal squamous cell carcinoma treated by definitive chemoradiotherapy
To investigate the value of CT radiomics features of meso-esophageal fat in the overall survival (OS) prediction of patien...
Outcome and prognostic factors of CBF pediatric AML patients with t(8;21) differ from patients with inv(16)
Outcome and prognostic factors of CBF pediatric AML patients with t(8;21) differ from patients with inv(16)
To explore the outcome and prognostic factors between inv(16) and t(8;21) disrupt core binding factor (CBF) in acute myelo...
Circulating tumor cells (CTCs) and hTERT gene expression in CTCs for radiotherapy effect with lung cancer
Circulating tumor cells (CTCs) and hTERT gene expression in CTCs for radiotherapy effect with lung cancer
Circulating tumor cells (CTCs) are important biological indicators of the lung cancer prognosis, and CTC counting and typi...
Efficacy and safety of PD-1/PD-L1 inhibitors combined with anti-angiogenic therapy for the unresectable hepatocellular carcinoma and the benefit for hepatitis B virus etiology subgroup: a systematic review and meta-analysis of randomized controlled trials
Efficacy and safety of PD-1/PD-L1 inhibitors combined with anti-angiogenic therapy for the unresectable hepatocellular carcinoma and the benefit for hepatitis B virus etiology subgroup: a systematic review and meta-analysis of randomized controlled trials
Hepatocellular carcinoma (HCC) is the third leading cause of cancer-related death, worldwide. The predominant causative fa...
Delay in diagnosis and associated factors among children with cancer admitted at pediatric oncology ward, University of Gondar comprehensive specialized hospital, Ethiopia: a retrospective cross-sectional study
Delay in diagnosis and associated factors among children with cancer admitted at pediatric oncology ward, University of Gondar comprehensive specialized hospital, Ethiopia: a retrospective cross-sectional study
Delay in the diagnosis of childhood cancer is one of the major health problem that contribute to decreased survival rates ...
Fusobacterium nucleatum-derived small extracellular vesicles facilitate tumor growth and metastasis via TLR4 in breast cancer
Fusobacterium nucleatum-derived small extracellular vesicles facilitate tumor growth and metastasis via TLR4 in breast cancer
The contributive role of the microbiome in tumor progression has been reported in multiple studies, such as the Fusobacter...
Aprepitant inhibits the development and metastasis of gallbladder cancer via ROS and MAPK activation
Aprepitant inhibits the development and metastasis of gallbladder cancer via ROS and MAPK activation
Aprepitant, as a neurokinin-1 receptor (NK-1R) antagonist, originally applied for curing chemotherapy-induced nausea and v...
Cervical cancer screening utilization and its predictors among women in bench Sheko Zone, Southwest Ethiopia: using health belief model
Cervical cancer screening utilization and its predictors among women in bench Sheko Zone, Southwest Ethiopia: using health belief model
Cervical cancer is the fourth most frequently diagnosed and found to be the leading cause of cancer death in women, especi...
Study protocol of an open-label, single arm phase II trial investigating the efficacy and safety of Trifluridine/Tipiracil combined with irinotecan as a second line therapy in patients with cholangiocarcinoma (TRITICC)
Study protocol of an open-label, single arm phase II trial investigating the efficacy and safety of Trifluridine/Tipiracil combined with irinotecan as a second line therapy in patients with cholangiocarcinoma (TRITICC)
The prognosis of patients with advanced biliary tract cancer (BTC) who have progressed on gemcitabine plus cisplatin is di...
Analysis of stromal PDGFR-β and α-SMA expression and their clinical relevance in brain metastases of breast cancer patients
Analysis of stromal PDGFR-β and α-SMA expression and their clinical relevance in brain metastases of breast cancer patients
Breast cancer brain metastasis (BCBM) is a growing therapeutic challenge and clinical concern. Stromal cancer-associated f...
Real-world practice of conversion surgery for unresectable hepatocellular carcinoma - a single center data of 26 consecutive patients
Real-world practice of conversion surgery for unresectable hepatocellular carcinoma - a single center data of 26 consecutive patients
To understand the proportion of uHCC (unresectable hepatocellular carcinoma) patients who achieve successful conversion re...
CCL19/CCR7 drives regulatory T cell migration and indicates poor prognosis in gastric cancer
CCL19/CCR7 drives regulatory T cell migration and indicates poor prognosis in gastric cancer
Gastric cancer is associated with significant morbidity and mortality in the world. Blocking programmed cell death protein...
Correction: Depletion of SOD2 enhances nasopharyngeal carcinoma cell radiosensitivity via ferroptosis induction modulated by DHODH inhibition
Correction: Depletion of SOD2 enhances nasopharyngeal carcinoma cell radiosensitivity via ferroptosis induction modulated by DHODH inhibition
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, whi...
Apatinib plus etoposide in pretreated patients with advanced triple-negative breast cancer: a phase II trial
Apatinib plus etoposide in pretreated patients with advanced triple-negative breast cancer: a phase II trial
Treatment options for pretreated triple-negative breast cancer (TNBC) are limited. This study aimed to evaluate the effica...
Correction: Shikonin inhibits cancer cell cycling by targeting Cdc25s
Correction: Shikonin inhibits cancer cell cycling by targeting Cdc25s
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, whi...
Estrogen receptor beta expression in triple negative breast cancers is not associated with recurrence or survival
Estrogen receptor beta expression in triple negative breast cancers is not associated with recurrence or survival
Triple negative BCa (TNBC) is defined by a lack of expression of estrogen (ERα), progesterone (PgR) receptors and hum...
PD-L1 stimulation can promote proliferation and survival of leukemic cells by influencing glucose and fatty acid metabolism in acute myeloid leukemia
PD-L1 stimulation can promote proliferation and survival of leukemic cells by influencing glucose and fatty acid metabolism in acute myeloid leukemia
Leukemic cell metabolism plays significant roles in their proliferation and survival. These metabolic adaptations are unde...
ACSL4 serves as a novel prognostic biomarker correlated with immune infiltration in Cholangiocarcinoma
ACSL4 serves as a novel prognostic biomarker correlated with immune infiltration in Cholangiocarcinoma
Cholangiocarcinoma (CHOL) is the second most common primary hepatic malignant tumor, following hepatocellular carcinoma (H...
Preoperative chemoradiotherapy using tegafur/uracil, oral leucovorin, and irinotecan (TEGAFIRI) followed by oxaliplatin-based chemotherapy as total neoadjuvant therapy for locally advanced rectal cancer: the study protocol for a phase II trial
Preoperative chemoradiotherapy using tegafur/uracil, oral leucovorin, and irinotecan (TEGAFIRI) followed by oxaliplatin-based chemotherapy as total neoadjuvant therapy for locally advanced rectal cancer: the study protocol for a phase II trial
Total neoadjuvant therapy (TNT) is a novel treatment strategy that is an alternative to preoperative chemoradiotherapy (CR...
Post-progression treatment in cancer randomized trials: a cross-sectional study of trials leading to FDA approval and published trials between 2018 and 2020
Post-progression treatment in cancer randomized trials: a cross-sectional study of trials leading to FDA approval and published trials between 2018 and 2020
Suboptimal treatment upon progression may affect overall survival (OS) results in oncology randomized controlled trials (R...
A randomized trial to evaluate the effects of a supervised exercise program on insomnia in patients with non-metastatic breast cancer undergoing chemotherapy: design of the FATSOMCAN study
A randomized trial to evaluate the effects of a supervised exercise program on insomnia in patients with non-metastatic breast cancer undergoing chemotherapy: design of the FATSOMCAN study
Up to 70% of breast cancer patients report symptoms of insomnia during and after treatment. Despite the ubiquity of insomn...
A comprehensive analysis of different types of databases reveals that CDH1 mRNA and E-cadherin protein are not downregulated in most carcinoma tissues and carcinoma cell lines
A comprehensive analysis of different types of databases reveals that CDH1 mRNA and E-cadherin protein are not downregulated in most carcinoma tissues and carcinoma cell lines
The CDH1 gene codes for the epithelial-cadherin (E-cad) protein, which is embedded in the plasma membrane of epithelial ce...
The impact of the COVID-19 pandemic restrictions on the health care utilization of cancer patients
The impact of the COVID-19 pandemic restrictions on the health care utilization of cancer patients
COVID-19 has impacted both society and medical care. While Germany entered the first lockdown in spring 2020, the PIKKO st...
ARHGAP39 is a prognostic biomarker involved in immune infiltration in breast cancer
ARHGAP39 is a prognostic biomarker involved in immune infiltration in breast cancer
Current studies on the role of ARHGAP39 mainly focused on its effect on neurodevelopment. However, there are few studies o...
Tumor–stroma ratio predicts prognosis and PD-L1 expression in hepatocellular carcinoma
Tumor–stroma ratio predicts prognosis and PD-L1 expression in hepatocellular carcinoma
With the in-depth research on the tumor microenvironment, the tumor stroma is considered to play a leading role in maligna...
阅读更多
format_indent_increase