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Anaesthesia for neurosurgery
Neurosurgery encompasses a wide range of intracranial and spinal procedures with evolving areas in awake craniotomies, fun...
Anaesthesia in the MRI unit
Magnetic resonance imaging (MRI) is a widely available imaging modality providing high-resolution images of soft tissues. ...
An updated review on the principles of intraoperative neurophysiological monitoring and the anaesthetic considerations
It is known that any surgery to the nervous system poses risks to neural structures and their surrounding structures. Thes...
Pharmacological and pathological modulation of cerebral physiology
Homeostatic mechanisms exist to enable the supply of oxygen and glucose for cerebral metabolism and neuronal function. In ...
Anaesthesia for awake craniotomy
Awake craniotomy enables intraoperative assessment of a patient's neurological status. It is most commonly performed for t...
Acute management of ischaemic stroke
An acute ischaemic stroke (AIS) is a non-specific state of brain injury with neuronal dysfunction, which has several patho...
A clinical approach to coma: neurological assessment of the comatose patient
Coma, from the Greek ‘deep sleep’ or ‘trance’, is a state of profound unrousable unresponsiveness in which the patient lie...
The management of spontaneous primary intracerebral haemorrhage
Intracerebral haemorrhage (ICH) accounts for around 10–20% of all strokes and results from a variety of disorders. ICH is ...
Prion diseases
The prion diseases, or transmissible spongiform encephalopathies (TSEs), are a group of neurodegenerative diseases. They a...
Ion channels, receptors, agonists and antagonists
This article describes the physiology of ion channels and the principal molecular mechanisms responsible for modulating th...
Therapeutic hypothermia and acute brain injury
The potential benefits of therapeutic hypothermia (TH) have been recognized for decades; however, despite a strong scienti...
Applied cerebral physiology
The brain is an exquisitely sensitive organ, requiring a constant supply of blood, oxygen, and glucose to function. Cerebr...
Anaesthesia for neurointerventional radiology
Neurointerventional radiology (NIR) for the diagnosis and treatment of neurological conditions has undergone significant a...
Regional anaesthesia for ophthalmic surgery
Available online 25 October 2022AbstractOphthalmic surgery can be conducted under local anaesthesia (LA), with techniques ...
Tracheal intubation
Available online 17 October 2022AbstractTracheal intubation is the act of placing a tube into the trachea thus enabling ox...
Perioperative management of allergic risks
Available online 13 October 2022AbstractHypersensitivity reactions are abnormal adverse reactions to stimuli that are usua...
Neuromuscular function and transmission
Available online 13 October 2022AbstractUnderstanding the biological processes and mechanisms underlying neuromuscular fun...
Perioperative management of the older patient
Available online 7 October 2022AbstractWith an ageing population, anaesthetists have increasing importance in taking care ...
Eye signs in anaesthesia and intensive care
Available online 4 October 2022AbstractOphthalmology can be unfamiliar territory for the anaesthetist and intensivist. Thi...
Data, information, knowledge, wisdom and understanding
Available online 4 October 2022AbstractThe digital age commenced in the mid-20th century and since we have seen approximat...
General anaesthesia for ophthalmic surgery
Available online 4 October 2022AbstractThe majority of ophthalmic surgeries are performed as day cases under topical or re...
Anaesthesia for eye surgery in paediatrics
Available online 4 October 2022AbstractIn contrast to adult practice, the majority of paediatric eye surgery is performed ...
Ocular anatomy and physiology relevant to anaesthesia
Available online 4 October 2022AbstractAn understanding of the anatomy of the orbit is essential for performing regional a...
Physiology of ageing
Available online 4 October 2022AbstractThe impact that ageing has on organisms is a complex interaction between the proces...
Postoperative pulmonary complications and their prevention
Available online 5 October 2022AbstractPostoperative pulmonary complications are common. Despite advances in perioperative...
Care of the eye during anaesthesia and intensive care
Available online 5 October 2022AbstractThis article describes care of the eye through a period of potential vulnerability,...
Privacy, confidentiality, and security of healthcare information
Available online 5 October 2022AbstractPatients must trust doctors, their decisions and actions; this confidence extends t...
Pathophysiology of respiratory disease and its significance to anaesthesia
Available online 5 October 2022AbstractSignificant changes occur in the respiratory system during anaesthesia. The changes...
Chemical casualties – a clinical overview
Chemical weapons are a diverse range of substances that can be used to cause intentional death or harm through their toxic...
Extracorporeal support of the respiratory system
Available online 22 September 2022AbstractExtracorporeal membrane oxygenation (ECMO) support of the respiratory system has...