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Kidney and Mortality Outcomes Associated with Ondansetron in Critically Ill Patients
Kidney and Mortality Outcomes Associated with Ondansetron in Critically Ill Patients
Background: Ondansetron is a preferred anti-emetic in critical care to treat nausea and vomiting, and has historically bee...
The Growth of Palliative Practice and End of Life Care in an Academic Teaching Intensive Care Unit
The Growth of Palliative Practice and End of Life Care in an Academic Teaching Intensive Care Unit
ObjectiveDying in the intensive care unit (ICU) has changed over the last twenty years due to increased utilization of pal...
Recent Advances in Bedside Device-Based Early Detection of Sepsis
Recent Advances in Bedside Device-Based Early Detection of Sepsis
Early detection of sepsis is challenging to achieve with current diagnostic methods, leading to expenditures of $27 billio...
Assessment of Safety of Remdesivir in Covid −19 Patients with Estimated Glomerular Filtration Rate (eGFR) < 30 ml/min per 1.73 m^2
Assessment of Safety of Remdesivir in Covid −19 Patients with Estimated Glomerular Filtration Rate (eGFR) < 30 ml/min per 1.73 m^2
PurposeSafety of remdesivir in patients with renal impairment is unknown. Incidence of liver injury secondary to remdesivi...
The Continuing Effect of COVID-19 Pandemic on Physical Well-Being and Mental Health of ICU Healthcare Workers in Turkey: A Single-Centre Cross-Sectional Later-Phase Study
The Continuing Effect of COVID-19 Pandemic on Physical Well-Being and Mental Health of ICU Healthcare Workers in Turkey: A Single-Centre Cross-Sectional Later-Phase Study
BackgroundThis study aimed to evaluate the effect of COVID-19 pandemic on physical well-being and mental health of ICU hea...
Association of Surge Conditions with Mortality Among Critically Ill Patients with COVID-19
Association of Surge Conditions with Mortality Among Critically Ill Patients with COVID-19
ObjectiveTo determine whether surge conditions were associated with increased mortality.DesignMulticenter cohort study.Set...
Intensive Care Unit Sedation Practices at a Large, Tertiary Academic Center
Intensive Care Unit Sedation Practices at a Large, Tertiary Academic Center
BackgroundSedatives are frequently administered in an ICU and are often dependent on patient population and ICU type. Thes...
Family Outcomes After the Pediatric Intensive Care Unit: A Scoping Review
Family Outcomes After the Pediatric Intensive Care Unit: A Scoping Review
BackgroundIntensivists are increasingly attuned to the postdischarge outcomes experienced by families because patient reco...
Long-Term Follow up of Renal and Other Acute Organ Failure in Survivors of Critical Illness Due to Covid-19
Long-Term Follow up of Renal and Other Acute Organ Failure in Survivors of Critical Illness Due to Covid-19
BackgroundLittle is known about the long-term health sequelae and outcomes of various organ failures in ICU survivors of C...
Diagnostic Sensitivity of Plasma Endothelin-1 for Cerebral Vasospasm After Subarachnoid Hemorrhage, a Multicentre Double-Blind Study
Diagnostic Sensitivity of Plasma Endothelin-1 for Cerebral Vasospasm After Subarachnoid Hemorrhage, a Multicentre Double-Blind Study
The purpose of this study is to establish the diagnostic sensitivity of Endothelin-1 for risk stratification and screening...
Bag-Mask Ventilation Versus Apneic Oxygenation During Tracheal Intubation in Critically Ill Adults: A Secondary Analysis of 2 Randomized Trials
Bag-Mask Ventilation Versus Apneic Oxygenation During Tracheal Intubation in Critically Ill Adults: A Secondary Analysis of 2 Randomized Trials
Background: Hypoxemia is common during tracheal intubation in intensive care units. To prevent hypoxemia during intubation...
Needs Assessment Survey Identifying Research Processes Which may be Improved by Automation or Artificial Intelligence: ICU Community Modeling and Artificial Intelligence to Improve Efficiency (ICU-Comma)
Needs Assessment Survey Identifying Research Processes Which may be Improved by Automation or Artificial Intelligence: ICU Community Modeling and Artificial Intelligence to Improve Efficiency (ICU-Comma)
BackgroundCritical care research in Canada is conducted primarily in academically-affiliated intensive care units with est...
Analysis of Intent and Reason for Oncologic Therapy Administration in Cancer Patients Admitted to the Intensive Care Unit
Analysis of Intent and Reason for Oncologic Therapy Administration in Cancer Patients Admitted to the Intensive Care Unit
PurposeTo investigate the intent of, and reason for, administration of oncologic therapies in the intensive care unit (ICU...
High- Versus Low-Dose Dexamethasone for the Treatment of COVID-19-Related Acute Respiratory Distress Syndrome: A Multicenter, Randomized Open-Label Clinical Trial
High- Versus Low-Dose Dexamethasone for the Treatment of COVID-19-Related Acute Respiratory Distress Syndrome: A Multicenter, Randomized Open-Label Clinical Trial
ObjectiveTo determine whether high-dose dexamethasone increases the number of ventilator-free days (VFD) among patients wi...
External Validation of the Cardiac Surgery Score in a Quaternary Hospital in the United States of America
External Validation of the Cardiac Surgery Score in a Quaternary Hospital in the United States of America
BackgroundThe Cardiac Surgery Score (CASUS) was developed to assist in predicting post-cardiac surgery mortality using par...
Delirium in a Tertiary Pediatric Cardiac Intensive Care Unit: Risk Factors and Outcomes
Delirium in a Tertiary Pediatric Cardiac Intensive Care Unit: Risk Factors and Outcomes
ObjectiveDelirium is an increasingly recognized hospital complication associated with poorer outcomes in critically ill ch...
Patterns of Delirium in a Pediatric Intensive Care Unit and Associations With Noise Pollution
Patterns of Delirium in a Pediatric Intensive Care Unit and Associations With Noise Pollution
ObjectiveDelirium is a common problem in the Pediatric Intensive Care Unit (PICU) and is associated with increased length ...
Reverse Bayesian Implications of p-Values Reported in Critical Care Randomized Trials
Reverse Bayesian Implications of p-Values Reported in Critical Care Randomized Trials
BackgroundMisinterpretations of the p-value in null-hypothesis statistical testing are common. We aimed to determine the i...
Five-Year Outcomes After Implementing a Pain, Agitation, and Delirium Protocol in a Mixed Intensive Care Unit
Five-Year Outcomes After Implementing a Pain, Agitation, and Delirium Protocol in a Mixed Intensive Care Unit
Objective: Assess for continued improvements in patient outcomes after updating our institutional sedation and analgesia p...
Thrombosis and Bleeding After Implementation of an Intermediate-Dose Prophylactic Anticoagulation Protocol in ICU Patients With COVID-19: A Multicenter Screening Study
Thrombosis and Bleeding After Implementation of an Intermediate-Dose Prophylactic Anticoagulation Protocol in ICU Patients With COVID-19: A Multicenter Screening Study
Thrombosis and bleeding after implementation of an intermediate-dose prophylactic anticoagulation protocol in intensive ca...
Effect of Premorbid Beta-Blockers on Mortality in Patients With Sepsis: A Systematic Review and Meta-Analysis
Effect of Premorbid Beta-Blockers on Mortality in Patients With Sepsis: A Systematic Review and Meta-Analysis
ObjectiveThe aim of this study was to conduct a systematic review and meta-analysis to investigate the impact of premorbid...
Latin American Consensus on the Management of Sepsis in Children: Sociedad Latinoamericana de Cuidados Intensivos Pediátricos [Latin American Pediatric Intensive Care Society] (SLACIP) Task Force: Executive Summary
Latin American Consensus on the Management of Sepsis in Children: Sociedad Latinoamericana de Cuidados Intensivos Pediátricos [Latin American Pediatric Intensive Care Society] (SLACIP) Task Force: Executive Summary
1. Martischang, R, Pires, D, Masson-Roy, S, et al. Promoting and sustaining a historical and global effort to prevent seps...
Shock Index, Modified Shock Index and MELD as Predictors of Mortality for Critically Ill Patients With Liver Disease
Shock Index, Modified Shock Index and MELD as Predictors of Mortality for Critically Ill Patients With Liver Disease
1. Everhart, JE, Ruhl, CE. Burden of digestive diseases in the United States part III: liver, biliary tract, and pancreas....
Outcomes of Continuous Renal Replacement Therapy in a Community Health System
Outcomes of Continuous Renal Replacement Therapy in a Community Health System
ObjectiveContinuous renal replacement therapy (CRRT) is commonly used in critically ill, hemodynamically unstable patients...
Use of High-Flow Nasal Cannula in Patients With Pneumonia and Hypoxemic Respiratory Failure at Altitudes Above 2600 m: What Is the Best Predictor of Success?
Use of High-Flow Nasal Cannula in Patients With Pneumonia and Hypoxemic Respiratory Failure at Altitudes Above 2600 m: What Is the Best Predictor of Success?
Introduction: The use of high-flow nasal cannulas (HFNC) in patients with hypoxemic ventilatory failure reduces the need f...
Posttraumatic Stress Namong Pediatric Critical Care Physicians in the United States in Association with Coronavirus Disease 2019 Patient Care Experiences
Posttraumatic Stress Namong Pediatric Critical Care Physicians in the United States in Association with Coronavirus Disease 2019 Patient Care Experiences
Posttraumatic stress among pediatric critical care physicians in the United States in association with coronavirus disease...
Impact of Underlying Congestive Heart Failure on In-Hospital Outcomes in Patients with Septic Shock
Impact of Underlying Congestive Heart Failure on In-Hospital Outcomes in Patients with Septic Shock
Purpose: Septic shock (SS) manifests with profound circulatory and cellular metabolism abnormalities and has a high in-hos...
ST-Elevation Myocardial Infarction Among Septic Shock and Coronary Interventions: A National Emergency Database Study
ST-Elevation Myocardial Infarction Among Septic Shock and Coronary Interventions: A National Emergency Database Study
ObjectiveTo study coronary interventions and mortality among patients with ST-elevated myocardial infarction (STEMI) who w...
Reactivation of EBV and CMV in Severe COVID-19—Epiphenomena or Trigger of Hyperinflammation in Need of Treatment? A Large Case Series of Critically ill Patients
Reactivation of EBV and CMV in Severe COVID-19—Epiphenomena or Trigger of Hyperinflammation in Need of Treatment? A Large Case Series of Critically ill Patients
BackgroundReactivation of viruses such as Epstein-Barr virus (EBV) and cytomegalovirus (CMV) are common in critically ill ...
Temporal Trends in the Microbiological Characteristics of Sepsis in the United States: A Population Based Study
Temporal Trends in the Microbiological Characteristics of Sepsis in the United States: A Population Based Study
BackgroundEpidemiologic studies are needed for monitoring population-level trends in sepsis. This study examines sepsis-ca...
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