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Nanogap traps for passive bacteria concentration and single-point confocal Raman spectroscopy
Nanogap traps for passive bacteria concentration and single-point confocal Raman spectroscopy
A microfluidic device enabling the isolation and concentration of bacteria for analysis by confocal Raman spectroscopy is ...
On-chip dielectrophoretic device for cancer cell manipulation: A numerical and artificial neural network study
On-chip dielectrophoretic device for cancer cell manipulation: A numerical and artificial neural network study
Breast cancer, as one of the most frequent types of cancer in women, imposes large financial and human losses annually. MC...
Recent advances in label-free optical, electrochemical, and electronic biosensors for glioma biomarkers
Recent advances in label-free optical, electrochemical, and electronic biosensors for glioma biomarkers
Gliomas are the most commonly occurring primary brain tumor with poor prognosis and high mortality rate. Currently, the di...
Steering particles via micro-actuation of chemical gradients using model predictive control
Steering particles via micro-actuation of chemical gradients using model predictive control
Biological systems rely on chemical gradients to direct motion through both chemotaxis and signaling, but synthetic approa...
Herringbone micromixers for particle filtration
Herringbone micromixers for particle filtration
Herringbone micromixers are a powerful tool for introducing advection into microfluidic systems. While these mixers are ty...
Cell counting and velocity algorithms for hydrodynamic study of unsteady biological flows in micro-channels
Cell counting and velocity algorithms for hydrodynamic study of unsteady biological flows in micro-channels
In this paper, the combination of two algorithms, a cell counting algorithm and a velocity algorithm based on a Digital Pa...
Universal pre-mixing dry-film stickers capable of retrofitting existing microfluidics
Universal pre-mixing dry-film stickers capable of retrofitting existing microfluidics
Integrating microfluidic mixers into lab-on-a-chip devices remains challenging yet important for numerous applications inc...
Recent advances in microfluidic-based cancer immunotherapy-on-a-chip strategies
Recent advances in microfluidic-based cancer immunotherapy-on-a-chip strategies
Despite several extraordinary improvements in cancer immunotherapy, its therapeutic effectiveness against many distinct ca...
Microinjection in C. elegans by direct penetration of elastomeric membranes
Microinjection in C. elegans by direct penetration of elastomeric membranes
The nematode worm C. elegans is widely used in basic and translational research. The creation of transgenic strains by inj...
Paper-based evaporation concentrators: Comparison of linear and radial geometries
Paper-based evaporation concentrators: Comparison of linear and radial geometries
Paper-based evaporation concentrators with linear and radial geometries are compared. A new method of finding approximate ...
3D collagen microchamber arrays for combined chemotherapy effect evaluation on cancer cell numbers and migration
3D collagen microchamber arrays for combined chemotherapy effect evaluation on cancer cell numbers and migration
Breast cancer metastasis involves complex mechanisms, particularly when patients are undergoing chemotherapy. In tissues, ...
A passive and programmable 3D paper-based microfluidic pump for variable flow microfluidic applications
A passive and programmable 3D paper-based microfluidic pump for variable flow microfluidic applications
Paper has attracted significant attention recently as a microfluidic component and platform, especially in passive pumping...
Phenotyping of rare circulating cells in the blood of non-metastatic breast cancer patients using microfluidic Labyrinth technology
Phenotyping of rare circulating cells in the blood of non-metastatic breast cancer patients using microfluidic Labyrinth technology
Label-free technologies for isolating rare circulating cells in breast cancer patients are widely available; however, they...
Surface-limited reactions for spatial control of kinesin–microtubule motility assays using indirect irradiation of an electron beam
Surface-limited reactions for spatial control of kinesin–microtubule motility assays using indirect irradiation of an electron beam
Gliding of microtubules (MTs) on kinesins has been applied to lab-on-a-chip devices, which enable autonomous transportatio...
Transfer of blocker-based qPCR reactions for DNA methylation analysis into a microfluidic LoC system using thermal modeling
Transfer of blocker-based qPCR reactions for DNA methylation analysis into a microfluidic LoC system using thermal modeling
Changes in the DNA methylation landscape are associated with many diseases like cancer. Therefore, DNA methylation analysi...
Scalable large-area mesh-structured microfluidic gradient generator for drug testing applications
Scalable large-area mesh-structured microfluidic gradient generator for drug testing applications
Microfluidic concentration gradient generators are useful in drug testing, drug screening, and other cellular applications...
Hematocrit skewness along sequential bifurcations within a microfluidic network induces significant changes in downstream red blood cell partitioning
Hematocrit skewness along sequential bifurcations within a microfluidic network induces significant changes in downstream red blood cell partitioning
There has been a wealth of research conducted regarding the partitioning of red blood cells (RBCs) at bifurcations within ...
I-LIFT (image-based laser-induced forward transfer) platform for manipulating encoded microparticles
I-LIFT (image-based laser-induced forward transfer) platform for manipulating encoded microparticles
Encoded microparticles have great potential in small-volume multiplexed assays. It is important to link the micro-level as...
Laser induced graphanized microfluidic devices
Laser induced graphanized microfluidic devices
With the advent of cyber-physical system-based automation and intelligence, the development of flexible and wearable devic...
Cell pairing for biological analysis in microfluidic devices
Cell pairing for biological analysis in microfluidic devices
Cell pairing at the single-cell level usually allows a few cells to contact or seal in a single chamber and provides high-...
Liver-on-a-chip: Considerations, advances, and beyond
Liver-on-a-chip: Considerations, advances, and beyond
The liver is the largest internal organ in the human body with largest mass of glandular tissue. Modeling the liver has be...
Water-in-water droplet microfluidics: A design manual
Water-in-water droplet microfluidics: A design manual
Droplet microfluidics is utilized in a wide range of applications in biomedicine and biology. Applications include rapid b...
Microfluidic-assisted fiber production: Potentials, limitations, and prospects
Microfluidic-assisted fiber production: Potentials, limitations, and prospects
Besides the conventional fiber production methods, microfluidics has emerged as a promising approach for the engineered sp...
Mechanical characterization of isolated mitochondria under conditions of oxidative stress
Mechanical characterization of isolated mitochondria under conditions of oxidative stress
Mechanical properties have been proven to be a pivotal parameter to enhance our understanding of living systems. While res...
Brain organoid-on-a-chip: A next-generation human brain avatar for recapitulating human brain physiology and pathology
Brain organoid-on-a-chip: A next-generation human brain avatar for recapitulating human brain physiology and pathology
Neurodegenerative diseases and neurodevelopmental disorders have become increasingly prevalent; however, the development o...
Nanoextraction based on surface nanodroplets for chemical preconcentration and determination
Nanoextraction based on surface nanodroplets for chemical preconcentration and determination
Liquid-liquid extraction based on surface nanodroplets, namely nanoextraction, can continuously extract and enrich target ...
Design of a flexing organ-chip to model in situ loading of the intervertebral disc
Design of a flexing organ-chip to model in situ loading of the intervertebral disc
The leading cause of disability of all ages worldwide is severe lower back pain. To address this untreated epidemic, furth...
DNA fragmentation in a steady shear flow
DNA fragmentation in a steady shear flow
We have determined the susceptibility of T4 DNA (166 kilobase pairs, kbp) to fragmentation under steady shear in a cone-an...
Biphasic flow dynamics and polarized mass transportation in branched hepatic sinusoids
Biphasic flow dynamics and polarized mass transportation in branched hepatic sinusoids
In fatty liver diseases, such as liver fibrosis and liver cirrhosis, blood flow in hepatic sinusoids, an elementary buildi...
Integration of hydrogels into microfluidic devices with porous membranes as scaffolds enables their drying and reconstitution
Integration of hydrogels into microfluidic devices with porous membranes as scaffolds enables their drying and reconstitution
Hydrogels are a critical component of many microfluidic devices. They have been used in cell culture applications, biosens...
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