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The interplay between cardiac dyads and mitochondria regulated the calcium handling in cardiomyocytes
The interplay between cardiac dyads and mitochondria regulated the calcium handling in cardiomyocytes
Calcium mishandling and mitochondrial dysfunction have been increasingly recognized as significant factors involved in the...
Critical periods in Drosophila neural network development: Importance to network tuning and therapeutic potential
Critical periods in Drosophila neural network development: Importance to network tuning and therapeutic potential
Critical periods are phases of heightened plasticity that occur during the development of neural networks. Beginning with ...
Autonomic imbalance and atrial ectopic activity—a pathophysiological and clinical view
Autonomic imbalance and atrial ectopic activity—a pathophysiological and clinical view
The heart is one of the most richly innervated organs and the impact of the complex cardiac autonomic network on atrial el...
Resting and exercise metabolic characteristics in obese children with insulin resistance
Resting and exercise metabolic characteristics in obese children with insulin resistance
Purpose: This study aimed to explore the characteristics of resting energy expenditure (REE) and lipid metabolism during i...
Validation of a simplified-geometry model of inhaled formoterol pharmacodynamics in asthmatic patients
Validation of a simplified-geometry model of inhaled formoterol pharmacodynamics in asthmatic patients
PharmacoKinetics (PK) and PharmacoDynamics (PD) mathematical models of inhaled bronchodilators represent useful tools for ...
Measurements on the external load acting on aquatic resistance fins during flexion/extension movements using a robotic joint
Measurements on the external load acting on aquatic resistance fins during flexion/extension movements using a robotic joint
Aquatic resistance training has been proven to be beneficial to many people, in particular those struggling with degenerat...
Heart rate reduction as a marker to optimize carvedilol treatment and enhance myocardial recovery in pediatric dilated cardiomyopathy
Heart rate reduction as a marker to optimize carvedilol treatment and enhance myocardial recovery in pediatric dilated cardiomyopathy
Introduction: An elevated heart rate is associated with an increased risk of death or cardiac transplant in children with ...
Endothelial deletion of the cytochrome P450 reductase leads to cardiac remodelling
Endothelial deletion of the cytochrome P450 reductase leads to cardiac remodelling
The cytochrome P450 reductase (POR) transfers electrons to all microsomal cytochrome P450 enzymes (CYP450) thereby driving...
Targeted differential photostimulation alters reproductive activities of domestic birds
Targeted differential photostimulation alters reproductive activities of domestic birds
Modern poultry production systems use environmentally controlled houses providing only artificial illumination. The role o...
Effects of kinesio taping therapy on gait and surface electromyography in stroke patients with hemiplegia
Effects of kinesio taping therapy on gait and surface electromyography in stroke patients with hemiplegia
Background: The application of Kinesio Taping (KT) on the lower extremity of stroke patients can improve the quality of so...
A deep feature fusion network for fetal state assessment
A deep feature fusion network for fetal state assessment
CTG (cardiotocography) has consistently been used to diagnose fetal hypoxia. It is susceptible to identifying the average ...
Effects of functional training on sprinting, jumping, and functional movement in athletes: A systematic review
Effects of functional training on sprinting, jumping, and functional movement in athletes: A systematic review
This systematic review aims to illuminate the effects of functional training on sprinting, jumping, and functional movemen...
Metabolic effects of alternate-day fasting in males with obesity with or without type 2 diabetes
Metabolic effects of alternate-day fasting in males with obesity with or without type 2 diabetes
Alternate-day fasting induces oscillations in energy stores. We hypothesized that repeated oscillations increases insulin ...
Modeling ameloblast-matrix interactions using 3D cell culture
Modeling ameloblast-matrix interactions using 3D cell culture
The distinct morphology adopted by ameloblasts during amelogenesis is highly stage specific and involved intimately with t...
Cerebral multimodality monitoring in adult neurocritical care patients with acute brain injury: A narrative review
Cerebral multimodality monitoring in adult neurocritical care patients with acute brain injury: A narrative review
Cerebral multimodality monitoring (MMM) is, even with a general lack of Class I evidence, increasingly recognized as a too...
Red blood cell proteomics reveal remnant protein biosynthesis and folding pathways in PIEZO1-related hereditary xerocytosis
Red blood cell proteomics reveal remnant protein biosynthesis and folding pathways in PIEZO1-related hereditary xerocytosis
Hereditary xerocytosis is a dominant red cell membrane disorder characterized by an increased leak of potassium from the i...
Molecular insights into the axon guidance molecules Sidestep and Beaten path
Molecular insights into the axon guidance molecules Sidestep and Beaten path
The transmembrane protein Sidestep (Side) functions as a substrate-bound attractant for motor axons in Drosophila. Outgrow...
Study on potential markers for diagnosis of renal cell carcinoma by serum untargeted metabolomics based on UPLC-MS/MS
Study on potential markers for diagnosis of renal cell carcinoma by serum untargeted metabolomics based on UPLC-MS/MS
Objective: Renal cell carcinoma (RCC) is the most common malignancy of the kidney. However, there is no reliable biomarker...
Transcription factor GATA6 promotes migration of human coronary artery smooth muscle cells in vitro
Transcription factor GATA6 promotes migration of human coronary artery smooth muscle cells in vitro
Vascular smooth muscle cell plasticity plays a pivotal role in the pathophysiology of vascular diseases. Despite compellin...
Glucose transporters GLUT1, GLUT3, and GLUT4 have different effects on osteoblast proliferation and metabolism
Glucose transporters GLUT1, GLUT3, and GLUT4 have different effects on osteoblast proliferation and metabolism
Bone is an active tissue that undergoes constant remodeling. Bone formation requires energy and one of the energy sources ...
Energy metabolic shift contributes to the phenotype modulation of maturation stage ameloblasts
Energy metabolic shift contributes to the phenotype modulation of maturation stage ameloblasts
Maturation stage ameloblasts (M-ABs) are responsible for terminal enamel mineralization in teeth and undergo characteristi...
Evaluation of the transverse aortic constriction model in ICR and C57BL/6J mice
Evaluation of the transverse aortic constriction model in ICR and C57BL/6J mice
Transverse aortic constriction (TAC) is a frequently used model to investigate pressure overload-induced progressive heart...
The effect of dobutamine on ocular blood flow of healthy adults: A 3D pseudocontinuous aterial spin labelling study
The effect of dobutamine on ocular blood flow of healthy adults: A 3D pseudocontinuous aterial spin labelling study
Purpose: Ocular blood flow (OBF) is an important risk factor for incidence, prevalence and progression of some ocular diso...
Manipulating plasma thyroid hormone levels alters development of endothermy and ventilation in nestling red-winged blackbirds
Manipulating plasma thyroid hormone levels alters development of endothermy and ventilation in nestling red-winged blackbirds
Thyroid hormones are key regulators of development and metabolism in vertebrates. During the nestling period, young of alt...
Skeletal muscle metabolism and contraction performance regulation by teneurin C-terminal-associated peptide-1
Skeletal muscle metabolism and contraction performance regulation by teneurin C-terminal-associated peptide-1
Skeletal muscle regulation is responsible for voluntary muscular movement in vertebrates. The genes of two essential prote...