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Phenotype Compensation in Reproductive ADAM Gene Family: A Case Study with ADAM27 Knockout Mouse
Background: A disintegrin and metalloproteinase (ADAM) cell surface proteins are expressed in different cells and are invo...
MiR-582 down-regulates Lissencephaly-1(LIS1) via P-Akt and MMP-2 to inhibit cholangiocarcinoma cell proliferation and invasion
Background:Cholangiocarcinoma is a primary malignant tumor, and its progression involves oncogene activation, tumor suppre...
Co-Expression Network Analysis of Soybean Transcriptome Identify Hub Genes Under Saline-Alkaline and Water Deficit Stress
Background: Soybean is an important oilseed crop that its development and production are affected by environmental stresse...
Impact of NOX4 knockout by CRISPR/Cas9 on the MCF-7, HCA-7 and UM-RC-6 cancer cells
Background: The second most common cause of mortality is cancer. Increased NOX4 expression is linked to cancer development...
Phenotype Compensation in Reproductive ADAM Gene Family: A Case Study with ADAM27 Knock-Out Mice
Background: A disintegrin and metalloproteinase (ADAM) cell surface proteins are expressed in different cells and are invo...
Fabrication and Characterization of pcDNA3.1(+) Location within Chitosan/Nanoparticles Complexes for Enhanced Gene Delivery
Background: Chitosan nanoparticles (CSNP) are becoming a popular alternative for delivering nucleic acids to tissues for g...
Acceleration of Yeast Autolysis by Addition of Fatty Acids, Ethanol and Alkaline Protease
Background: Autolysate products from yeast origin are very interesting for food, feed, cosmetic, pharmaceutical, and ferme...
Growth of Spirulina Maxima in an Optimized Concentric Internal Tube Photobioreactor
Background: Microalgae have the potential to generate high-value products. The design of photobioreactors (PBRs), in which...
The HLA rs9267649 and CYP24A1 rs2248359 Variants are Associated with Multiple Sclerosis: A Study on Iranian Population
Background: Studies have shown that MS results from synergism between genetic and environmental factors. As a genetic fact...
Ectopic expression of OCT4B1 Decreases Fertility Rate and Changes Sperm Parameters in Transgenic Mice
Background: The octamer-binding transcription factor-4 (OCT4) is known as an established important regulator of pluripoten...
A Novel Multi-Epitope ‎Edible Vaccine Candidate for Newcastle Disease Virus: In Silico Approach
Background: Newcastle disease, is one of the most important illnesses in the aviculture industry which shows a constant th...
The Gene manipulation and cellular immunotherapy combination in the treatment of cancer
The immune system is linked to the tumors from tumor formation to the tumor’s development and metastasis. So, the interest...
A Novel Multi-Epitope ‎Edible Vaccine Candidate for Newcastle Disease Virus: In Silico Approach
Background: Newcastle disease, is one of the most important illnesses in the aviculture industry which shows a constant th...
DGRanker: Cancer Driver Gene detection in Human Transcriptional Regulatory Network
Cancer is a group of diseases that have received much attention in biological research because of its high mortality rate ...
Bioremoval and Detoxification of Anthracene by a Halophilic Laccase From Alkalibacillus salilacus
Background: Polycyclic Aromatic Hydrocarbons (PAHs) as resistant compounds in the environment has received much attention ...
Epigenetic Alteration of DOK7 Gene CpG Island in Blood Leukocyte of Patients with Gastric Cancer and Intestinal Metaplasia
Background: Intestinal metaplasia (IM) is a benign lesion with no serious concern for patients' health. On the ot...
Rapid isolation of gastric adenocarcinoma cancer stem cells as a target for autologous dendritic cell-based immunotherapy-
Gastric cancer (GC) is one of the malignant neoplasms with a high death rate in the world. Cancer stem cells (CSCs) are a ...