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Temporal analysis of skeletal muscle remodeling post hindlimb ischemia reveals intricate autophagy regulation
Temporal analysis of skeletal muscle remodeling post hindlimb ischemia reveals intricate autophagy regulation
Hind limb ischemia (HLI) is the most severe form of peripheral arterial disease, associated with a substantial reduction o...
Role of noncoding RNAs in pancreatic ductal adenocarcinoma associated cachexia
Role of noncoding RNAs in pancreatic ductal adenocarcinoma associated cachexia
Cachexia is an acute syndrome that is very commonly observed in patients with cancer. Cachexia is the number one cause of ...
Squamous cell carcinoma of the tongue: subtypes and morphological features affecting prognosis
Squamous cell carcinoma of the tongue: subtypes and morphological features affecting prognosis
Squamous cell carcinoma (SCC) is the most common histological type of mobile tongue carcinoma. The incidence of mobile ton...
LncRNA NEAT1 accelerates renal fibrosis progression via targeting miR-31 and modulating RhoA/ROCK signal pathway
LncRNA NEAT1 accelerates renal fibrosis progression via targeting miR-31 and modulating RhoA/ROCK signal pathway
Renal fibrosis is the final pathway for chronic kidney disease to end-stage renal failure. Non-coding RNAs have been repor...
Atherosclerosis and Endothelial Mechanotransduction: Current Knowledge and Models for Future Research
Atherosclerosis and Endothelial Mechanotransduction: Current Knowledge and Models for Future Research
Endothelium health is essential to the regulation of physiological vascular functions. Because of the critical capability ...
Long non-coding RNA LINC01882 ameliorates aGVHD via skewing CD4+ T Cells differentiation towards Treg cells
Long non-coding RNA LINC01882 ameliorates aGVHD via skewing CD4+ T Cells differentiation towards Treg cells
Acute graft-versus-host disease (aGVHD) is a severe T cell-mediated immune response after allogeneic hematopoietic stem ce...
Altered intramuscular network of lipid droplets and mitochondria in type 2 diabetes
Altered intramuscular network of lipid droplets and mitochondria in type 2 diabetes
Excessive storage of lipid droplets (LDs) in skeletal muscles is a hallmark of type 2 diabetes. However, LD morphology dis...
Getting sweeter - New evidence for glucose transporters in specific cell types of the airway?
Getting sweeter - New evidence for glucose transporters in specific cell types of the airway?
New technologies such as single cell RNA sequencing (scRNAseq) has enabled identification of the mRNA transcripts expresse...
PCM1 labelling reveals myonuclear and nuclear dynamics in skeletal muscle across species.
PCM1 labelling reveals myonuclear and nuclear dynamics in skeletal muscle across species.
Myonuclei transcriptionally regulate muscle fibres during homeostasis and adaptation to exercise. Their cellular location ...
Hypoxia as a Regulator of Tumor Stroma and Metastasis
Hypoxia as a Regulator of Tumor Stroma and Metastasis
Metastasis is the leading cause of mortality in most cancer patients. Despite its clinical importance, mechanistic underpi...
Muscle plasticity is influenced by renal function and caloric intake through the FGF23-vitamin D axis
Muscle plasticity is influenced by renal function and caloric intake through the FGF23-vitamin D axis
Skeletal muscle, the main metabolic engine in the body of vertebrates, is endowed with great plasticity. The association b...
Red Light-Green Light: T-cell Trafficking in Cardiac and Vascular Inflammation
Red Light-Green Light: T-cell Trafficking in Cardiac and Vascular Inflammation
Extravasation of T cells from the bloodstream into inflamed tissues requires interactions between T cells and vascular end...
Therapeutic potential of antimicrobial peptides for treatment of wound infection
Therapeutic potential of antimicrobial peptides for treatment of wound infection
Healing of cutaneous wounds is a fundamental process required to re-establish tissue integrity, repair skin barrier functi...
Bi-directional sensitivity of CALHM1 channel to protons from both sides of plasma membrane
Bi-directional sensitivity of CALHM1 channel to protons from both sides of plasma membrane
Calcium homeostasis modulator 1 (CALHM1), a newly discovered voltage-dependent nonselective ion channel, has drawn attenti...
The basement membrane in epidermal polarity, stemness and regeneration
The basement membrane in epidermal polarity, stemness and regeneration
The epidermis is a specialized epithelium that constitutes the outermost layer of the skin, and it provides a protective b...
Tripartite motif-containing protein 32 (TRIM32) regulates Ca2+ movement in skeletal muscle
Tripartite motif-containing protein 32 (TRIM32) regulates Ca2+ movement in skeletal muscle
Mutations in tripartite motif-containing protein 32 (TRIM32), especially in NHL repeats, have been found in skeletal muscl...
Identification of underexplored mesenchymal and vascular-related cell populations in human skeletal muscle
Identification of underexplored mesenchymal and vascular-related cell populations in human skeletal muscle
Skeletal muscle repair and maintenance are directly and indirectly supported by stromal populations such as vascular cells...
Chemokine Physiology in Cancer
Chemokine Physiology in Cancer
Chemokines are chemotactic cytokines whose canonical functions govern movement of receptor expressing cells along chemical...