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A crucial Fusobacterium nucleatum clade in colorectal cancer
A crucial Fusobacterium nucleatum clade in colorectal cancer
A distinct Fusobacterium nucleatum clade, Fna C2, that is dominant in the human colorectal cancer (CRC) niche has been ide...
Artificial intelligence in liver cancer — new tools for research and patient management
Artificial intelligence in liver cancer — new tools for research and patient management
Liver cancer has high incidence and mortality globally. Artificial intelligence (AI) has advanced rapidly, influencing can...
Promoting allyship to support and uplift the LGBTQIA+ community
Promoting allyship to support and uplift the LGBTQIA+ community
The lesbian, gay, bisexual, transgender, queer, intersex and asexual (LGBTQIA+) community navigates a complex social lands...
Publisher Correction: Gastrointestinal and brain barriers: unlocking gates of communication across the microbiota–gut–brain axis
Authors and AffiliationsAPC Microbiome Ireland, University College Cork, Cork, IrelandMaría R. Aburto & John F. CryanD...
The changing metabolic landscape of bile acids – keys to metabolism and immune regulation
The changing metabolic landscape of bile acids – keys to metabolism and immune regulation
Bile acids regulate nutrient absorption and mitochondrial function, they establish and maintain gut microbial community co...
New understanding of hepatobiliary MRI
New understanding of hepatobiliary MRI
Magnetic resonance imaging following injection of hepatobiliary contrast agents improves the detection of hepatocellular c...
Improving culturally safe engagement with sexual and gender minority populations
Cultural safety seeks to remediate health inequities through empowering marginalized and minoritized patient populations, ...
Tackling sorbitol intolerance
Tackling sorbitol intolerance
Sorbitol, a poorly absorbable sweetener, is catabolized by gut microbiota, mainly Clostridia. Lee et al. now elucidate the...
HCC genomic landscape in Chinese individuals
Researchers from the Chinese Liver Cancer Atlas project performed deep whole-genome sequencing of hepatocellular carcinoma...
Seladelpar in primary biliary cholangitis
In a phase III, double-blind, placebo-controlled trial, 193 patients with primary biliary cholangitis and an inadequate re...
Bacteriophages and host inflammation in IBD
Researchers analysed metagenomic data from 1,618 patients with inflammatory bowel disease (IBD) and 791 healthy individual...
Biomarker shows no clinical use in guiding treatment for Crohn’s disease
Between 29 December 2017 and 5 January 2022, in a multicentre, open-label, biomarker-stratified, interventional clinical t...
Towards unifying fatty liver nomenclature: a voice from the Middle East and North Africa
Fatty liver disease is one of the most common liver diseases in the Middle East and North Africa region, and globally. Unf...
Future direction of total neoadjuvant therapy for locally advanced rectal cancer
Future direction of total neoadjuvant therapy for locally advanced rectal cancer
Despite therapeutic advancements, disease-free survival and overall survival of patients with locally advanced rectal canc...
Cell senescence in liver diseases: pathological mechanism and theranostic opportunity
Cell senescence in liver diseases: pathological mechanism and theranostic opportunity
The liver is not oblivious to the passage of time, as ageing is a major risk factor for the development of acute and chron...
ECCO’24
ECCO’24
In February 2024, Nature Reviews Gastroenterology & Hepatology attended the 19th Congress of ECCO (ECCO’24) in Stockho...
Screening for liver fibrosis: lessons from colorectal and lung cancer screening
Screening for liver fibrosis: lessons from colorectal and lung cancer screening
Many countries have incorporated population screening programmes for cancer, such as colorectal and lung cancer, into thei...
Group 3 innate lymphoid cells in intestinal health and disease
Group 3 innate lymphoid cells in intestinal health and disease
The gastrointestinal tract is an immunologically rich organ, containing complex cell networks and dense lymphoid structure...
2023 FDA approvals in gastroenterology and hepatology
2023 FDA approvals in gastroenterology and hepatology
In 2023, the Center for Drug Evaluation and Research (CDER) of the US Food and Drug Administration (FDA) approved 55 novel...
Another renaissance for bile acid gastrointestinal microbiology
Another renaissance for bile acid gastrointestinal microbiology
The field of bile acid microbiology in the gastrointestinal tract is going through a current rebirth after a peak of activ...
Ultra-processed foods and food additives in gut health and disease
Ultra-processed foods and food additives in gut health and disease
Ultra-processed foods (UPFs) and food additives have become ubiquitous components of the modern human diet. There is incre...
Author Correction: A new era in obesity management
Authors and AffiliationsMassachusetts General Hospital, MGH Weight Center, Department of Medicine-Division of Endocrinolog...
Sugemalimab with chemotherapy for advanced ESCC
A multicentre, randomized, double-blind, phase III trial reported positive results for sugemalimab (a PDL1 antibody) plus ...
A gut–liver axis in intestinal stem cell fitness
New research demonstrates that the gut–liver axis plays a part in calibrating intestinal stem cell (ISC) expansion during ...
GLP1 agonists and risk of major adverse liver outcomes
Glucagon-like peptide 1 (GLP1) agonists could be a treatment option to reduce risk of major adverse liver outcomes (MALO) ...
Live bacterial therapeutics for detection and treatment of colorectal cancer
Live bacterial therapeutics for detection and treatment of colorectal cancer
Live microorganisms can be manipulated and engineered for colorectal cancer detection and treatment through methods such a...
Gastrointestinal and brain barriers: unlocking gates of communication across the microbiota–gut–brain axis
Gastrointestinal and brain barriers: unlocking gates of communication across the microbiota–gut–brain axis
Crosstalk between gut and brain has long been appreciated in health and disease, and the gut microbiota is a key player in...
Resmetirom proves positive for NASH with liver fibrosis
Positive phase III results have been reported for resmetirom (a thyroid hormone receptor β-selective agonist) for the trea...
HCV direct-acting antiviral therapy adherence in people who inject drugs
A new study (HERO) published in the Journal of Hepatology has investigated the association between direct-acting antiviral...
Linaclotide for functional constipation in paediatric patients: phase III results
Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obta...
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