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Prevalence and risk of complications in untreated patients with adult growth hormone deficiency
Prevalence and risk of complications in untreated patients with adult growth hormone deficiency
Adult growth hormone deficiency (AGHD) increases the prevalence of complications, including metabolic disorder, leading to...
Reappraising prediction of surgical complexity of non-functioning pituitary adenomas after transsphenoidal surgery: the modified TRANSSPHER grade
Reappraising prediction of surgical complexity of non-functioning pituitary adenomas after transsphenoidal surgery: the modified TRANSSPHER grade
Prognostication of surgical complexity is crucial for optimizing decision-making and patient counseling in pituitary surge...
Exploring sex-specific hematological changes and their impact on quality of life in patients with prolactinoma
Exploring sex-specific hematological changes and their impact on quality of life in patients with prolactinoma
Despite prolactin´s (PRL) role in stimulating hematopoiesis, anemia is commonly observed in men with macroprolactinom...
Outcomes in surgical management of microprolactinomas: an international multi-institutional series
Outcomes in surgical management of microprolactinomas: an international multi-institutional series
Prolactinomas represent the most common pituitary adenoma subtype, the majority of which are microprolactinomas. Dopamine ...
The role of BRAF testing of Rathke’s cleft cysts to identify missed papillary craniopharyngioma
The role of BRAF testing of Rathke’s cleft cysts to identify missed papillary craniopharyngioma
The differential diagnosis of cystic sellar/suprasellar lesions includes craniopharyngioma (CP) and Rathke’s cleft c...
Hospital frailty risk score predicts postoperative outcomes after endoscopic endonasal resection of non-functioning pituitary adenomas
Hospital frailty risk score predicts postoperative outcomes after endoscopic endonasal resection of non-functioning pituitary adenomas
Frailty indices are invaluable resources in risk stratification and predicting high-value care outcomes for neurosurgical ...
Assessment of sarcopenic obesity in patients with acromegaly
Assessment of sarcopenic obesity in patients with acromegaly
Sarcopenic obesity (SO), a condition characterized by the coexistence of obesity and sarcopenia, has primarily been studie...
Medical management pathways for Cushing’s disease in pituitary tumors centers of excellence (PTCOEs)
Medical management pathways for Cushing’s disease in pituitary tumors centers of excellence (PTCOEs)
A recent update of consensus guidelines for the management of Cushing’s disease (CD) included indications for medica...
Osilodrostat improves blood pressure and glycemic control in patients with Cushing’s disease: a pooled analysis of LINC 3 and LINC 4 studies
Osilodrostat improves blood pressure and glycemic control in patients with Cushing’s disease: a pooled analysis of LINC 3 and LINC 4 studies
To evaluate the effect of osilodrostat and hypercortisolism control on blood pressure (BP) and glycemic control in patient...
Selective resection of the medial wall of the cavernous sinus in pituitary surgery: results of a prospective single center analysis
Selective resection of the medial wall of the cavernous sinus in pituitary surgery: results of a prospective single center analysis
Pituitary adenomas, despite their histologically benign nature, can severely impact patients’ quality of life due to...
Correlates of prolonged length of stay after endoscopic transsphenoidal surgery for pituitary adenomas: varying definitions and non-clinical factors
Correlates of prolonged length of stay after endoscopic transsphenoidal surgery for pituitary adenomas: varying definitions and non-clinical factors
Prolonged length of stay (PLOS) can lead to resource misallocation and higher complication risks. However, there is no con...
Sheehan syndrome: a current approach to a dormant disease
Sheehan syndrome: a current approach to a dormant disease
Sheehan syndrome (SS) is postpartum pituitary necrosis leading to severe hypopituitarism. Severe bleeding during delivery ...
Relationship between plasma urea and copeptin in response to arginine stimulation in healthy adults, patients with vasopressin deficiency and primary polydipsia
Relationship between plasma urea and copeptin in response to arginine stimulation in healthy adults, patients with vasopressin deficiency and primary polydipsia
Arginine infusion stimulates copeptin secretion, a surrogate marker of arginine vasopressin (AVP), thereby serving as a di...
Impact of insurance on outcomes of patients undergoing endoscopic transsphenoidal surgery for non-functional pituitary adenomas: a single institution study
Impact of insurance on outcomes of patients undergoing endoscopic transsphenoidal surgery for non-functional pituitary adenomas: a single institution study
Uninsured and underinsured patients face notable healthcare disparities in neurosurgery, but limited literature exists on ...
Treatment of acromegaly-induced diabetes: an updated proposal
Treatment of acromegaly-induced diabetes: an updated proposal
Acromegaly-induced diabetes presents unique features due to the direct effects of excess growth hormone (GH) and insulin-l...
Empty sella syndrome: an update
Empty sella syndrome: an update
Empty sella is characterized by a flattened profile of the pituitary gland that represents in most cases only a radiologic...
Sellar and perisellar meningiomas: effects on pituitary function in a Spanish cohort observational study
Sellar and perisellar meningiomas: effects on pituitary function in a Spanish cohort observational study
Studies focused on the effects of sellar and/or perisellar (S/PS) meningiomas on pituitary function are scarce. The primar...
Inflammation of adenohypophysis is commonly associated with headache in surgically managed Rathke’s cleft cysts
Inflammation of adenohypophysis is commonly associated with headache in surgically managed Rathke’s cleft cysts
Rathke’s cleft cysts (RCC) are present in up to 20% of autopsy studies but only a minority necessitate surgical trea...
Can we predict the risk of venous thromboembolism in patients with Cushing’s syndrome: a nationwide cohort analysis
Can we predict the risk of venous thromboembolism in patients with Cushing’s syndrome: a nationwide cohort analysis
Patients with Cushing’s syndrome (CS) have an increased venous thromboembolism (VTE) risk with most studies focusing...
The diagnostic value of prolactin adjustment in bilateral inferior petrosal sinus sampling for differentiating Cushing’s disease from the ectopic ACTH syndrome: a systematic review and meta-analysis
The diagnostic value of prolactin adjustment in bilateral inferior petrosal sinus sampling for differentiating Cushing’s disease from the ectopic ACTH syndrome: a systematic review and meta-analysis
Adrenocorticotropin (ACTH)-dependent Cushing’s syndrome can arise from a pituitary tumour (Cushing’s disease) ...
Effects of growth hormone replacement therapy in childhood-onset craniopharyngioma: an updated systematic review and meta-analysis
Effects of growth hormone replacement therapy in childhood-onset craniopharyngioma: an updated systematic review and meta-analysis
Craniopharyngiomas (CPs) often lead to growth hormone deficiency (GHD) in children. Growth hormone replacement therapy (GH...
IGF-I levels during standard Lanreotide dose predicts biochemical outcome of high-frequency regimen in acromegaly
IGF-I levels during standard Lanreotide dose predicts biochemical outcome of high-frequency regimen in acromegaly
First-generation somatostatin receptor ligands (fg-SRLs) are the cornerstone of acromegaly treatment. Additional benefits ...
Substance P and Neurokinin-1 receptor are overexpressed in adamantinomatous craniopharyngioma than in the pituitary gland
Substance P and Neurokinin-1 receptor are overexpressed in adamantinomatous craniopharyngioma than in the pituitary gland
Human adamantinomatous craniopharyngioma (ACP) is a brain tumor that originates at the base of the skull and shows aggress...
Management policy for postoperative acromegaly patients with normal IGF-1 and high GH levels on oral glucose tests
Management policy for postoperative acromegaly patients with normal IGF-1 and high GH levels on oral glucose tests
Acromegaly patients occasionally achieve either of the remission criterion of IGF-1 or GH level postoperatively; however, ...
Novel approach to bone comorbidity in resistant acromegaly
Novel approach to bone comorbidity in resistant acromegaly
Active acromegaly may lead to irreversible complications. Among them, acromegaly osteopathy and fragility (vertebral and h...
Hypopituitarism and COVID-19
Hypopituitarism and COVID-19
This review aims to collect and examine recent research findings regarding hypopituitarism and COVID-19, focusing on the v...
Modern approach to bone comorbidity in prolactinoma
Modern approach to bone comorbidity in prolactinoma
Prolactinomas account for more than half of pituitary adenomas, and besides their clinical impact on fertility and gonadal...
Cushing’s syndrome and COVID-19
Cushing’s syndrome and COVID-19
This review aims to present current data on the course of COVID-19 in patients with Cushing syndrome (CS) and discuss trea...
Approach to the patient with controlled acromegaly and acromegalic arthropathy: clinical diagnosis and management
Approach to the patient with controlled acromegaly and acromegalic arthropathy: clinical diagnosis and management
Following the description of an illustrative case of a 70-year-old female patient with longstanding active acromegaly and ...
Growth hormone and bone: a basic perspective
Growth hormone and bone: a basic perspective
Growth hormone is fundamental for growth during childhood and for maintaining bone mass and homeostasis in the adults. GH ...
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